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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Sotalol PIS1M1 Sotalol PIS1M2 Sotalol Sotalol Sotalol PIS1M1 Sotalol PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Sotalol undergoes metabolism to give Sotalol PIS1M1 and Sotalol PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Sotalol PIS1M1 Sotalol PIS1M2 Sotalol Sotalol Sotalol PIS1M1 Sotalol PIS1M2 Urinary Excretion and/or Bile duct Excretion