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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Ziprasidone PIS1M1 Ziprasidone PIS1M2 Ziprasidone Ziprasidone Ziprasidone PIS1M1 Ziprasidone PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Ziprasidone undergoes metabolism to give Ziprasidone PIS1M1 and Ziprasidone PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Ziprasidone PIS1M1 Ziprasidone PIS1M2 Ziprasidone Ziprasidone Ziprasidone PIS1M1 Ziprasidone PIS1M2 Urinary Excretion and/or Bile duct Excretion