Loader
Loading Pathway...
Unknown Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Midodrine Midodrine Midodrine PIS1M1 Midodrine PIS1M2 Esmolol PIS1M3 Midodrine PIS1M1 Midodrine PIS1M2 Esmolol PIS1M3 Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Sildenafil undergoes metabolism to give Sildenafil PIS1M1, Sildenafil PIS1M2 and Sildenafil PIS1M3.
Endoplasmic Reticulum Unknown Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 Midodrine Midodrine Midodrine PIS1M1 Midodrine PIS1M2 Esmolol PIS1M3 Midodrine PIS1M1 Midodrine PIS1M2 Esmolol PIS1M3 Urinary Excretion and/or Bile duct Excretion