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Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Azithromycin PIS2M1 Azithromycin PIS2M1 Azithromycin PIS1M1 Azithromycin PIS1M1 Azithromycin Azithromycin Azithromycin PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Azithromycin undergoes metabolism to give Azithromycin PIS1M1, Azithromycin PIS1M2 and Azithromycin PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown CYP3A4 CYP3A4 CYP3A4 Azithromycin PIS2M1 Azithromycin PIS2M1 Azithromycin PIS1M1 Azithromycin PIS1M1 Azithromycin Azithromycin Azithromycin PIS1M2 Urinary Excretion and/or Bile duct Excretion