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Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Sulfadimethoxine PIS2M1 Sulfadimethoxine PIS2M1 Sulfadimethoxine PIS1M1 Sulfadimethoxine PIS1M1 Sulfadimethoxine Sulfadimethoxine Sulfadimethoxine PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Sulfadimethoxine undergoes metabolism to give Sulfadimethoxine PIS1M1, Sulfadimethoxine PIS1M2 and Sulfadimethoxine PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown CYP3A4 CYP3A4 CYP3A4 Sulfadimethoxine PIS2M1 Sulfadimethoxine PIS2M1 Sulfadimethoxine PIS1M1 Sulfadimethoxine PIS1M1 Sulfadimethoxine Sulfadimethoxine Sulfadimethoxine PIS1M2 Urinary Excretion and/or Bile duct Excretion