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Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Vindesine PIS2M1 Vindesine PIS2M1 Vindesine PIS1M1 Vindesine PIS1M1 Vindesine Vindesine Vindesine PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Vindesine undergoes metabolism to give Vindesine PIS1M1, Vindesine PIS1M2 and Vindesine PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown CYP3A4 CYP3A4 CYP3A4 Vindesine PIS2M1 Vindesine PIS2M1 Vindesine PIS1M1 Vindesine PIS1M1 Vindesine Vindesine Vindesine PIS1M2 Urinary Excretion and/or Bile duct Excretion