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Unknown Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Acenocoumarol Acenocoumarol Acenocoumarol PIS1M1 Acenocoumarol PIS1M2 Acenocoumarol PIS1M3 Acenocoumarol PIS1M3 Acenocoumarol PIS1M1 Acenocoumarol PIS1M2 Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Acenocoumarol undergoes metabolism to give Acenocoumarol PIS1M1, Acenocoumarol PIS1M2 and Acenocoumarol PIS1M3.
Endoplasmic Reticulum Unknown Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 Acenocoumarol Acenocoumarol Acenocoumarol PIS1M1 Acenocoumarol PIS1M2 Acenocoumarol PIS1M3 Acenocoumarol PIS1M3 Acenocoumarol PIS1M1 Acenocoumarol PIS1M2 Urinary Excretion and/or Bile duct Excretion