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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Amisulpride Amisulpride Amisulpride PIS1M2 Amisulpride PIS2M1 Amisulpride PIS2M1 Amisulpride PIS1M1 Amisulpride PIS1M2 Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Amisulpride undergoes metabolism to give Amisulpride PIS1M1, Amisulpride PIS1M2 and Amisulpride PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 Amisulpride Amisulpride Amisulpride PIS1M2 Amisulpride PIS2M1 Amisulpride PIS2M1 Amisulpride PIS1M1 Amisulpride PIS1M2 Urinary Excretion and/or Bile duct Excretion