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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Terazosin Terazosin Terazosin PIS1M2 Terazosin PIS2M1 Terazosin PIS2M1 Terazosin PIS1M1 Terazosin PIS1M2 Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Terazosin undergoes metabolism to give Terazosin PIS1M1, Terazosin PIS1M2 and Terazosin PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 Terazosin Terazosin Terazosin PIS1M2 Terazosin PIS2M1 Terazosin PIS2M1 Terazosin PIS1M1 Terazosin PIS1M2 Urinary Excretion and/or Bile duct Excretion