Loader
Loading Pathway...
Unknown Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Tolfenamic acid Tolfenamic acid Tolfenamic acid PIS1M2 Tolfenamic acid PIS1M3 Tolfenamic acid PIS1M3 Tolfenamic acid PIS2M1 Tolfenamic acid PIS2M1 Tolfenamic acid PIS1M1 Tolfenamic acid PIS1M2 Heme Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Tolfenamic acid undergoes metabolism to give Tolfenamic acid PIS1M1, Tolfenamic acid PIS1M2, Tolfenamic acid PIS1M3 and Tolfenamic acid PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 CYP3A4 Tolfenamic acid Tolfenamic acid Tolfenamic acid PIS1M2 Tolfenamic acid PIS1M3 Tolfenamic acid PIS1M3 Tolfenamic acid PIS2M1 Tolfenamic acid PIS2M1 Tolfenamic acid PIS1M1 Tolfenamic acid PIS1M2 Urinary Excretion and/or Bile duct Excretion