Loader
Loading Pathway...
Unknown Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Zileuton Zileuton Zileuton PIS2M2 Zileuton PIS2M2 Zileuton PIS1M1 Zileuton PIS1M1 Zileuton PIS2M1 Zileuton PIS2M1 Zileuton PIS1M2 Zileuton PIS1M3 Heme Heme Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Zileuton undergoes metabolism to give Zileuton PIS1M1, Zileuton PIS1M2, Zileuton PIS1M3, Zileuton PIS1M4 and Zileuton PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 CYP3A4 CYP3A4 Zileuton Zileuton Zileuton PIS2M2 Zileuton PIS2M2 Zileuton PIS1M1 Zileuton PIS1M1 Zileuton PIS2M1 Zileuton PIS2M1 Zileuton PIS1M2 Zileuton PIS1M3 Urinary Excretion and/or Bile duct Excretion