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3-methyl-2- oxobutanoate dehydrogenase (Lipoamide) E1-alpha chain 3-methyl-2- oxobutanoate dehydrogenase (Lipoamide) E1-alpha chain Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Acyl-CoA dehydrogenase Fatty acid oxidation complex alpha-subunit Unknown Dehydrogenase Aldehyde dehydrogenase Acyl-CoA synthetase, long-chain fatty-acid:CoA ligase methylmalonyl-CoA mutase Branched-chain- amino-acid aminotransferase Thiamine pyrophosphate Succinyl-CoA α-Ketoisovaleric acid 2-Methyl-1- hydroxypropyl- ThPP CO2 Lipoamide Thiamine pyrophosphate S-(2- Methylpropionyl)- dihydrolipoamide- E CoA Isobutyryl-CoA Dihydrolipoamide Acceptor Methacrylyl-CoA Reduced acceptor H2O (S)-3- Hydroxyisobutyryl- CoA H2O (S)-3- Hydroxyisobutyric acid CoA NAD (S)-Methylmalonic acid semialdehyde NADH H+ NAD H2O Methylmalonic acid NADH H+ CoA ATP AMP Diphosphoric acid Methylmalonyl-CoA L-Valine NADP H2O NH3 NADPH H+ TCA Cycle Cytoplasm Gram-Negative Bacteria Periplasmic Space Outer Membrane Inner Membrane
bkdA bkdA bkdC fadE4 fadB1 Unknown SAVERM_1542 aldH fadD13 mcmB ilvE Thiamine pyrophosphate Succinyl-CoA α-Ketoisovaleric acid 2-Methyl-1- hydroxypropyl- ThPP Carbon dioxide Lipoamide Thiamine pyrophosphate S-(2- Methylpropionyl)- dihydrolipoamide- E Coenzyme A Isobutyryl-CoA Dihydrolipoamide Acceptor Methacrylyl-CoA Reduced acceptor Water (S)-3- Hydroxyisobutyryl- CoA Water (S)-3- Hydroxyisobutyric acid Coenzyme A NAD (S)-Methylmalonic acid semialdehyde NADH Hydrogen Ion NAD Water Methylmalonic acid NADH Hydrogen Ion Coenzyme A Adenosine triphosphate Adenosine monophosphate Diphosphoric acid Methylmalonyl-CoA L-Valine NADP Water Ammonia NADPH Hydrogen Ion TCA Cycle