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Branched-chain- amino-acid aminotransferase 3-methyl-2- oxobutanoate dehydrogenase (Lipoamide) E1-alpha chain 3-methyl-2- oxobutanoate dehydrogenase (Lipoamide) E1-alpha chain Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Acyl-CoA dehydrogenase Fatty acid oxidation complex alpha-subunit Fatty acid oxidation complex alpha-subunit 3-ketoacyl-CoA thiolase/acetyl- CoA acetyltransferase Acyl-CoA carboxylase, beta subunit Lipoamide L-Isoleucine NAD H2O NH3 NADH H+ (3S)-3-Methyl- 2-oxopentanoate Thiamine pyrophosphate 2-Methyl-1- hydroxypropyl- ThPP CO2 Thiamine pyrophosphate S-(2- Methylbutanoyl)- dihydrolipoamide CoA (S)-2- Methylbutanoyl- CoA Dihydrolipoamide Acceptor Reduced acceptor Tiglyl-CoA H2O 2-Methyl-3- hydroxybutyryl- CoA NAD 2- Methylacetoacetyl- CoA NADH H+ CoA Propionyl-CoA Acetyl-CoA CO2 Methylmalonyl-CoA Cytoplasm Gram-Negative Cell Periplasm Outer Membrane Inner Membrane Plasmid
ilvE bkdA bkdA bkdC fadE4 fadB1 fadB1 fadA8 accD4 Lipoamide L-Isoleucine NAD Water Ammonia NADH Hydrogen Ion (3S)-3-Methyl- 2-oxopentanoate Thiamine pyrophosphate 2-Methyl-1- hydroxypropyl- ThPP Carbon dioxide Thiamine pyrophosphate S-(2- Methylbutanoyl)- dihydrolipoamide Coenzyme A (S)-2- Methylbutanoyl- CoA Dihydrolipoamide Acceptor Reduced acceptor Tiglyl-CoA Water 2-Methyl-3- hydroxybutyryl- CoA NAD 2- Methylacetoacetyl- CoA NADH Hydrogen Ion Coenzyme A Propionyl-CoA Acetyl-CoA Carbon dioxide Methylmalonyl-CoA
ilvE bkdA bkdA bkdC fadE4 fadB1 fadB1 fadA8 accD4 Lipoamd Ile NAD H2O NH3 NADH H+ 3-3-M- ThiamPP 2M1ThPP CO2 ThiamPP S2MD CoA S-2-M-C DHLipoa Accep Red acc Tig-CoA H2O 2M3HC NAD 2Ma-CoA NADH H+ CoA PropCoA Ac-CoA CO2 Mal-CoA Cytoplasm Gram-Negative Cell Periplasm Outer Membrane Inner Membrane Plasmid
ilvE bkdA bkdA bkdC fadE4 fadB1 fadB1 fadA8 accD4 Lipoamd Ile NAD H2O NH3 NADH H+ 3-3-M- ThiamPP 2M1ThPP CO2 ThiamPP S2MD CoA S-2-M-C DHLipoa Accep Red acc Tig-CoA H2O 2M3HC NAD 2Ma-CoA NADH H+ CoA PropCoA Ac-CoA CO2 Mal-CoA