PathWhiz

Pathway Description

Pyruvate Decarboxylation to Acetyl-CoA

Fusobacterium varium ATCC 27725

Metabolic Pathway

The multi-enzyme complex catalyze three reactions that constitute a cycle, which is an essential source of acetyl-CoA. Pyruvate dehydrogenase E1 and dihydrolipoyllysine-residue acetyltransferase catalyzes pyruvic acid to acetyl-CoA and CO2. Acetyl-CoA is required for the TCA cycle. Lipoamide dehydrogenase reduces NAD+ to NADH.

References

Pyruvate Decarboxylation to Acetyl-CoA References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from PW002083

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		Acetyl-CoA
		Carbon dioxide
		Coenzyme A
		Hydrogen Ion
		NAD
		NADH
		Pyruvic acid

Visualize Protein Data

		Mercury(II) reductase family protein
		Transketolase, thiamine diphosphate binding domain protein
		Unknown

Clear

Downloads

SVG Image

Simple SVG Image

Greyscale SVG Image

BioPAX

SBGN

SBML

PWML

PNG Image

All files (.zip)

Settings