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Mitochondrial
pyruvate
carrier 1
Pyruvate
dehydrogenase
complex
Citrate synthase,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
beta,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
gamma,
mitochondrial
Oxoglutarate
dehydrogenase
complex
Succinyl-CoA
ligase
Fumarate
hydratase,
mitochondrial
Pyruvate
carboxylase,
mitochondrial
Succinate
dehydrogenase
Aconitate
hydratase,
mitochondrial
Aconitate
hydratase,
mitochondrial
Pyruvic acid
Oxalacetic acid
Fumaric acid
Succinic acid
FADH2
Oxoglutaric acid
Acetyl-CoA
Pyruvic acid
CoA
NAD
CO2
NADH
H2 O
Citric acid
CoA
Isocitric acid
NAD
CO2
NADH
H+
NAD
CoA
Succinyl-CoA
NADH
H+
CO2
Pi
GDP
CoA
GTP
L-Malic acid
H2 O
NAD
NADH
H+
ATP
HCO3 -
ADP
Pi
Q
FAD
QH2
cis-Aconitic acid
H2 O
H2 O
Thiamine
pyrophosphate
Lipoamide
FAD
Magnesium
Thiamine
pyrophosphate
Lipoamide
FAD
Biotin
Manganese
4Fe-4S
4Fe-4S
Gluconeogenesis
Glycolysis
Pyruvate
Metabolism
Malate-
Aspartate
Shuttle
Gluconeogenesis
Alanine
Metabolism
Aspartate
Metabolism
Pyruvate
Metabolism
Aspartate
Metabolism
Tyrosine
Metabolism
Arginine and
Proline
Metabolism
Urea Cycle
Propanoate
Metabolism
Mitochondrial
Electron
Transport Chain
Malate-
Aspartate
Shuttle
Glutamate
Metabolism
Alanine
Metabolism
Gluconeogenesis
Glucose-Alanine
Cycle
Valine,
Leucine, and
Isoleucine
Degradation
Tryptophan
Metabolism
Pyruvate
Metabolism
Fatty Acid
Metabolism
Ketone Body
Metabolism
Lysine
Degradation
Oxidation of
Branched-Chain
Fatty Acids
Propanoate
Metabolism
Isocitrate
dehydrogenase
[NAD] subunit
alpha,
mitochondrial
Inner mitochondrial membrane
Mitochondrial intermembrane
space
Cytosol
Mitochondrial matrix
Mitochondrion
Intracellular Space
Inner mitochondrial membrane
Outer mitochondrial membrane