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Pathways

PathWhiz ID Pathway Meta Data

PW000074

Pw000074 View Pathway
disease

5-Oxoprolinuria

Homo sapiens
5-Oxoprolinuria (5-Oxoprolinase deficiency) is a result of a defect in the gamma-glutamyl cycle due to either 5-oxoprolinase or glutathione synthetase deficiency. In the case of glutathione synthetase deficiency, the glycine is not incorporated into gamma-glutamylcysteine. In the case of 5-oxoprolinase, however, pyroglutamic acid accumulates. Symptoms include anemia, mental retardation, metabolic acidosis, respiratory distress and urolithiasis.

PW127179

Pw127179 View Pathway
disease

5-Oxoprolinuria

Homo sapiens
5-Oxoprolinuria (5-Oxoprolinase deficiency) is a result of a defect in the gamma-glutamyl cycle due to either 5-oxoprolinase or glutathione synthetase deficiency. In the case of glutathione synthetase deficiency, the glycine is not incorporated into gamma-glutamylcysteine. In the case of 5-oxoprolinase, however, pyroglutamic acid accumulates. Symptoms include anemia, mental retardation, metabolic acidosis, respiratory distress and urolithiasis.

PW121697

Pw121697 View Pathway
disease

5-Oxoprolinuria

Mus musculus
5-Oxoprolinuria (5-Oxoprolinase deficiency) is a result of a defect in the gamma-glutamyl cycle due to either 5-oxoprolinase or glutathione synthetase deficiency. In the case of glutathione synthetase deficiency, the glycine is not incorporated into gamma-glutamylcysteine. In the case of 5-oxoprolinase, however, pyroglutamic acid accumulates. Symptoms include anemia, mental retardation, metabolic acidosis, respiratory distress and urolithiasis.

PW146992

Pw146992 View Pathway
metabolic

9-cis-Retinoic acid Drug Metabolism Pathway

Homo sapiens

PW122161

Pw122161 View Pathway
physiological

a

Andrographolide

PW064708

Pw064708 View Pathway
disease

a

Bacteria

PW124259

Pw124259 View Pathway
protein

a

Homo sapiens

PW012863

Pw012863 View Pathway
signaling

A20 mechanism pathway

Homo sapiens

PW122528

Pw122528 View Pathway
signaling

A20 mechanism pathway 1560515737

Homo sapiens

PW123596

Pw123596 View Pathway
signaling

A20 mechanism pathway 1560515737 1568969187

Homo sapiens