PathWhiz ID | Pathway | Meta Data |
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PW132278View Pathway |
Undecoylium chloride iodine complex Drug MetabolismHomo sapiens
Undecoylium chloride iodine complex is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Undecoylium chloride iodine complex passes through the liver and is then excreted from the body mainly through the kidney.
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Creator: Ray Kruger Created On: September 21, 2023 at 20:35 Last Updated: September 21, 2023 at 20:35 |
PW146123View Pathway |
drug action
Undecoylium chloride iodine complex Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:28 Last Updated: October 07, 2023 at 17:28 |
PW146241View Pathway |
drug action
Undecylenic acid Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:45 Last Updated: October 07, 2023 at 17:45 |
PW123869View Pathway |
Unico ajajajHomo sapiens
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Creator: Johann Created On: April 24, 2020 at 15:38 Last Updated: April 24, 2020 at 15:38 |
PW145826View Pathway |
drug action
Unoprostone Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 16:45 Last Updated: October 07, 2023 at 16:45 |
PW132444View Pathway |
Upadacitinib Drug MetabolismHomo sapiens
Upadacitinib is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Upadacitinib passes through the liver and is then excreted from the body mainly through the kidney.
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Creator: Ray Kruger Created On: September 21, 2023 at 21:49 Last Updated: September 21, 2023 at 21:49 |
PW146906View Pathway |
drug action
Upadacitinib Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 19:19 Last Updated: October 07, 2023 at 19:19 |
PW123957View Pathway |
signaling
UPRMus musculus
UPR
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Creator: Guest: Anonymous Created On: July 03, 2020 at 15:45 Last Updated: July 03, 2020 at 15:45 |
PW002026View Pathway |
Uracil Degradation IIIEscherichia coli
Uracil is a pyrimidine nucleobase found in RNA, and can be used as a source of nitrogen for E. coli. There are at least three pathways through which uracil is degraded. This one begins with uracil, which originates from purine degradation. The putative monooxygenase enzyme rutA catalyzes the breakdown of uracil into peroxyaminoacrylate, using FMNH2 as a cofactor. Peroxyaminoacrylate is then broken down into both carbamic acid and 3-aminoacrylate following the addition of a water molecule by the putative isochorismatase family protein rutB. Carbamic acid can then spontaneously, with the addition of a hydrogen ion, split into an ammonium ion and a molecule of carbon dioxide. 3-aminoacrylate, on the other hand, is catalyzed by the UPF0076 protein rutC to form 2-aminoacrylic acid. This compound enters into a reaction catalyzed by protein rutD, which adds a water molecule and hydrogen ion and forms malonic semialdehyde with ammonium being a byproduct. Finally, the putative NADH dehydrogenase/NAD(P)H nitroreductase rutE complex converts malonic semialdehyde into hydroxypropionic acid, which is then used to form other necessary chemicals. The ammonium ions produced will be the important source of nitrogen for the bacteria.
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Creator: Ana Marcu Created On: October 01, 2015 at 14:20 Last Updated: October 01, 2015 at 14:20 |
PW123529View Pathway |
Uracil Degradation IIIPseudomonas aeruginosa
Uracil is a pyrimidine nucleobase found in RNA, and can be used as a source of nitrogen for E. coli. There are at least three pathways through which uracil is degraded. This one begins with uracil, which originates from purine degradation. The putative monooxygenase enzyme rutA catalyzes the breakdown of uracil into peroxyaminoacrylate, using FMNH2 as a cofactor. Peroxyaminoacrylate is then broken down into both carbamic acid and 3-aminoacrylate following the addition of a water molecule by the putative isochorismatase family protein rutB. Carbamic acid can then spontaneously, with the addition of a hydrogen ion, split into an ammonium ion and a molecule of carbon dioxide. 3-aminoacrylate, on the other hand, is catalyzed by the UPF0076 protein rutC to form 2-aminoacrylic acid. This compound enters into a reaction catalyzed by protein rutD, which adds a water molecule and hydrogen ion and forms malonic semialdehyde with ammonium being a byproduct. Finally, the putative NADH dehydrogenase/NAD(P)H nitroreductase rutE complex converts malonic semialdehyde into hydroxypropionic acid, which is then used to form other necessary chemicals. The ammonium ions produced will be the important source of nitrogen for the bacteria.
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Creator: Ana Marcu Created On: August 12, 2019 at 22:26 Last Updated: August 12, 2019 at 22:26 |