PathWhiz

PathWhiz ID	Pathway	Meta Data
PW146741 View Pathway	drug action Acetyl sulfisoxazole Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 18:56 Last Updated: October 07, 2023 at 18:56
PW132441 View Pathway	metabolic Acetyl sulfisoxazole Drug Metabolism Homo sapiens Acetyl sulfisoxazole is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Acetyl sulfisoxazole passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 21:48 Last Updated: September 21, 2023 at 21:48
PW128457 View Pathway	drug action Acetyl sulfisoxazole Action Pathway Escherichia coli (strain K12) Acetyl sulfisoxazole is an antibacterial from the sulfanilamide drug class. It is a broad-spectrum antibiotic indicated against urinary tract infections, meningococcal meningitis, acute otitis media, inclusion conjunctivitis, toxoplasmosis, and many others. Acetyl sulfisoxazole is a synthetic bacteriostatic, meaning that it stops the bacteria from growing. This drug binds competitively to the dihydropteroate synthase enzyme. This enzyme is essential to produce dihydrofolic acid in bacteria, when it is inhibited, the bacteria cannot grow anymore because they cannot produce DNA with the folic acid. Thus drug is administered as an oral tablet. N1-acetyl sulfisoxazole is metabolized to sulfisoxazole by digestive enzymes in the gastrointestinal tract and is absorbed as sulfisoxazole (the active compound). BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: August 29, 2023 at 12:52 Last Updated: August 29, 2023 at 12:52
PW124173 View Pathway	metabolic acetyl CoA production by PDH and Krebs cycle human metabolic pathway of acetyl CoA production by PDH and Krebs cycle BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: September 22, 2020 at 15:42 Last Updated: September 22, 2020 at 15:42
PW145155 View Pathway	drug action Acetophenazine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:11 Last Updated: October 07, 2023 at 15:11
PW124480 View Pathway	metabolic Acetonitrile Metabolism Homo sapiens Methyl cyanide (acetonitrile) is metabolized to citrate, succinate, fumarate, malate, glutamate, pyrrolidonecarboxylic acid and aspartate. Non-radioactive acetamide and acetate compete with 14C from methyl cyanide, and [2-14C]acetate and [2-14C]methyl cyanide are metabolized at similar rates, giving identical products. This evidence, combined with the inhibitory effect of fluoroacetate and arsenite on methyl cyanide metabolism, indicates that the pathway is: methyl cyanide leads to acetamide leads to acetate leads to tricarboxylic acid-cycle intermediates. The pathway was investigated in a species of Pseudomonas (group III; N.C.I.B. 10477), but comparison of labelling patterns suggests that it also exists in several higher plants. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Anastasija Petrovic Created On: January 25, 2021 at 21:30 Last Updated: January 25, 2021 at 21:30
PW144668 View Pathway	drug action Acetohydroxamic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:10 Last Updated: October 07, 2023 at 14:10
PW132160 View Pathway	metabolic Acetohydroxamic acid Drug Metabolism Homo sapiens Acetohydroxamic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Acetohydroxamic acid passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 19:45 Last Updated: September 21, 2023 at 19:45
PW144539 View Pathway	drug action Acetohexamide Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:51 Last Updated: October 07, 2023 at 13:51
PW145526 View Pathway	drug action Acetic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:00 Last Updated: October 07, 2023 at 16:00