PathWhiz

PathWhiz ID	Pathway	Meta Data
PW124480 View Pathway	metabolic Acetonitrile Metabolism Homo sapiens Methyl cyanide (acetonitrile) is metabolized to citrate, succinate, fumarate, malate, glutamate, pyrrolidonecarboxylic acid and aspartate. Non-radioactive acetamide and acetate compete with 14C from methyl cyanide, and [2-14C]acetate and [2-14C]methyl cyanide are metabolized at similar rates, giving identical products. This evidence, combined with the inhibitory effect of fluoroacetate and arsenite on methyl cyanide metabolism, indicates that the pathway is: methyl cyanide leads to acetamide leads to acetate leads to tricarboxylic acid-cycle intermediates. The pathway was investigated in a species of Pseudomonas (group III; N.C.I.B. 10477), but comparison of labelling patterns suggests that it also exists in several higher plants. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Anastasija Petrovic Created On: January 25, 2021 at 21:30 Last Updated: January 25, 2021 at 21:30
PW144668 View Pathway	drug action Acetohydroxamic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:10 Last Updated: October 07, 2023 at 14:10
PW132160 View Pathway	metabolic Acetohydroxamic acid Drug Metabolism Homo sapiens Acetohydroxamic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Acetohydroxamic acid passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 19:45 Last Updated: September 21, 2023 at 19:45
PW144539 View Pathway	drug action Acetohexamide Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:51 Last Updated: October 07, 2023 at 13:51
PW145526 View Pathway	drug action Acetic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:00 Last Updated: October 07, 2023 at 16:00
PW132172 View Pathway	metabolic Acetic acid Drug Metabolism Homo sapiens Acetic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Acetic acid passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 19:55 Last Updated: September 21, 2023 at 19:55
PW122272 View Pathway	metabolic acetic acid 1540693663 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: October 27, 2018 at 20:27 Last Updated: October 27, 2018 at 20:27
PW144925 View Pathway	drug action Acetazolamide Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:43 Last Updated: October 07, 2023 at 14:43
PW123646 View Pathway	metabolic Acetate Metabolism 1573342891 Escherichia coli BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: November 09, 2019 at 16:41 Last Updated: November 09, 2019 at 16:41
PW002090 View Pathway	metabolic Acetate Metabolism Escherichia coli The acetate biosynthesis starts with acetyl-CoA reacting with phosphate through a phosphate acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate. The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of a diphosphate, an AMP and an acetyl-CoA. Acetyl-CoA can be biosynthesized by acetoacetate reacting with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and an acetoacetyl-CoA. The acetoacetyl-CoA reacts with an acetyl-CoA acetyltransferase resulting in the release of an coenzyme A and 2 acetyl-CoA BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: October 13, 2015 at 15:14 Last Updated: October 13, 2015 at 15:14