PathWhiz ID | Pathway | Meta Data |
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PW000714View Pathway |
drug action
Abacavir Action PathwayHomo sapiens
Abacavir (also known as Ziagen or Epzicom) is an antiviral agent that is used for treating HIV/AID. Cellular enzyme converts abacavir to its activate metabolite, carbovir triphosphate, for inhibiting HIV-1 reverse transcriptase (RT) by competing with dGTP, which is the natural substrate of RT. Without HIV-1 reverse transcriptase, complementary DNA (cDNA) could not be generated; therefore, viral DNA couldn't be completed.
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Creator: WishartLab Created On: June 23, 2014 at 06:10 Last Updated: June 23, 2014 at 06:10 |
PW123594View Pathway |
AarginineHomo sapiens
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Creator: Guest: Anonymous Created On: September 17, 2019 at 03:22 Last Updated: September 17, 2019 at 03:22 |
PW064722View Pathway |
signaling
AAHomo sapiens
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Creator: Guest: Anonymous Created On: April 19, 2018 at 08:57 Last Updated: April 19, 2018 at 08:57 |
PW123596View Pathway |
signaling
A20 mechanism pathway 1560515737 1568969187Homo sapiens
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Creator: Guest: Anonymous Created On: September 20, 2019 at 02:46 Last Updated: September 20, 2019 at 02:46 |
PW122528View Pathway |
signaling
A20 mechanism pathway 1560515737Homo sapiens
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Creator: Guest: Anonymous Created On: June 14, 2019 at 07:35 Last Updated: June 14, 2019 at 07:35 |
PW012863View Pathway |
signaling
A20 mechanism pathwayHomo sapiens
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Creator: Guest: Anonymous Created On: November 16, 2016 at 00:18 Last Updated: November 16, 2016 at 00:18 |
PW128481View Pathway |
drug action
a Action PathwayHomo sapiens
Human thrombin is a platelet-activating factor also known under the brand names Artiss, Evarrest, Evicel, Evithrom, Tachosil, Tisseel and Vistaseal. Human thrombin is purified human thrombin, a highly specific serine protease that acts on fibrinogen to fibrin, leading to the formation of a blood clot. It also acts on coagulation factor XIII to activate it and establish cross-linking of fibrin producing a clot. It is used as a topical application to a surgical site to minimize bleeding. Human thrombin is metabolized the same way as endogenous thrombin, inactivated by plasma inhibitors.
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Creator: Selena Created On: August 30, 2023 at 20:25 Last Updated: August 30, 2023 at 20:25 |
PW122161View Pathway |
physiological
aAndrographolide
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Creator: Guest: Anonymous Created On: September 19, 2018 at 07:07 Last Updated: September 19, 2018 at 07:07 |
PW064708View Pathway |
disease
aBacteria
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Creator: Guest: Anonymous Created On: March 29, 2018 at 01:51 Last Updated: March 29, 2018 at 01:51 |
PW124259View Pathway |
protein
aHomo sapiens
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Creator: Guest: Anonymous Created On: October 20, 2020 at 23:11 Last Updated: October 20, 2020 at 23:11 |