PathWhiz

PathWhiz ID	Pathway	Meta Data
PW000093 View Pathway	disease Canavan Disease Homo sapiens Canavan Disease (Canavan-Van Bogaert-Bertrand Disease; Aminoacylase 2 Deficiency; Spongy Degeneration of the Central Nervous System; Aspartoacylase Deficiency; ASP Deficiency; ACY2 Deficiency; ASPA) is a rare autosomal recessive disease caused by a defect in the ASPA gene which codes for aspartoacylase. A deficiency in this enzyme results in accumulation of N-Acetyl-L-aspartic acid in plasma, spinal fluid, and urine. Symptoms, which present at birth, include myclonus, irritability, hypotonia, motor retardation, and poor head control. The neurological complications are due to demyelination of neurons and leukodystrophy. Premature death often results, though lithium citrate can be used as a treatment. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: August 01, 2013 at 15:52 Last Updated: August 01, 2013 at 15:52
PW121937 View Pathway	disease Canavan Disease Rattus norvegicus Canavan Disease (Canavan-Van Bogaert-Bertrand Disease; Aminoacylase 2 Deficiency; Spongy Degeneration of the Central Nervous System; Aspartoacylase Deficiency; ASP Deficiency; ACY2 Deficiency; ASPA) is a rare autosomal recessive disease caused by a defect in the ASPA gene which codes for aspartoacylase. A deficiency in this enzyme results in accumulation of N-Acetyl-L-aspartic acid in plasma, spinal fluid, and urine. Symptoms, which present at birth, include myclonus, irritability, hypotonia, motor retardation, and poor head control. The neurological complications are due to demyelination of neurons and leukodystrophy. Premature death often results, though lithium citrate can be used as a treatment. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: September 10, 2018 at 15:51 Last Updated: September 10, 2018 at 15:51
PW127346 View Pathway	disease Canavan Disease Homo sapiens Canavan Disease (Canavan-Van Bogaert-Bertrand Disease; Aminoacylase 2 Deficiency; Spongy Degeneration of the Central Nervous System; Aspartoacylase Deficiency; ASP Deficiency; ACY2 Deficiency; ASPA) is a rare autosomal recessive disease caused by a defect in the ASPA gene which codes for aspartoacylase. A deficiency in this enzyme results in accumulation of N-Acetyl-L-aspartic acid in plasma, spinal fluid, and urine. Symptoms, which present at birth, include myclonus, irritability, hypotonia, motor retardation, and poor head control. The neurological complications are due to demyelination of neurons and leukodystrophy. Premature death often results, though lithium citrate can be used as a treatment. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: December 13, 2022 at 16:24 Last Updated: December 13, 2022 at 16:24
PW121712 View Pathway	disease Canavan Disease Mus musculus Canavan Disease (Canavan-Van Bogaert-Bertrand Disease; Aminoacylase 2 Deficiency; Spongy Degeneration of the Central Nervous System; Aspartoacylase Deficiency; ASP Deficiency; ACY2 Deficiency; ASPA) is a rare autosomal recessive disease caused by a defect in the ASPA gene which codes for aspartoacylase. A deficiency in this enzyme results in accumulation of N-Acetyl-L-aspartic acid in plasma, spinal fluid, and urine. Symptoms, which present at birth, include myclonus, irritability, hypotonia, motor retardation, and poor head control. The neurological complications are due to demyelination of neurons and leukodystrophy. Premature death often results, though lithium citrate can be used as a treatment. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: September 10, 2018 at 15:49 Last Updated: September 10, 2018 at 15:49
PW145882 View Pathway	drug action Canagliflozin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:53 Last Updated: October 07, 2023 at 16:53
PW176363 View Pathway	metabolic Camphor Predicted Metabolism Pathway Homo sapiens Metabolites of Camphor are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: December 07, 2023 at 15:49 Last Updated: December 07, 2023 at 15:49
PW145498 View Pathway	drug action Camphor Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:56 Last Updated: October 07, 2023 at 15:56
PW123600 View Pathway	signaling cAMP signalling Bos taurus BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: September 24, 2019 at 03:36 Last Updated: September 24, 2019 at 03:36
PW126957 View Pathway	metabolic Camellia nitidissima triterpenoid biosynthesis 1653525001 Camellia nitidissima Camellia nitidissima is common traditional ethnic medicine in Guangxi, which takes effect by clearing away heat and toxic materials and diuretic detumescence. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: May 25, 2022 at 18:30 Last Updated: May 25, 2022 at 18:30
PW126956 View Pathway	metabolic Camellia nitidissima triterpenoid biosynthesis 1653524811 Camellia nitidissima Camellia nitidissima is common traditional ethnic medicine in Guangxi, which takes effect by clearing away heat and toxic materials and diuretic detumescence. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: May 25, 2022 at 18:26 Last Updated: May 25, 2022 at 18:26