PathWhiz

PathWhiz ID	Pathway	Meta Data
PW146029 View Pathway	drug action Technetium Tc-99m pyrophosphate Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:14 Last Updated: October 07, 2023 at 17:14
PW132252 View Pathway	metabolic Technetium Tc-99m sestamibi Drug Metabolism Homo sapiens Technetium Tc-99m sestamibi is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Technetium Tc-99m sestamibi passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 20:24 Last Updated: September 21, 2023 at 20:24
PW146026 View Pathway	drug action Technetium Tc-99m sestamibi Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:14 Last Updated: October 07, 2023 at 17:14
PW132255 View Pathway	metabolic Technetium Tc-99m succimer Drug Metabolism Homo sapiens Technetium Tc-99m succimer is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Technetium Tc-99m succimer passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 20:25 Last Updated: September 21, 2023 at 20:25
PW146153 View Pathway	drug action Technetium Tc-99m succimer Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:32 Last Updated: October 07, 2023 at 17:32
PW146135 View Pathway	drug action Technetium Tc-99m sulfur colloid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:29 Last Updated: October 07, 2023 at 17:29
PW132262 View Pathway	metabolic Technetium Tc-99m tetrofosmin Drug Metabolism Homo sapiens Technetium Tc-99m tetrofosmin is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Technetium Tc-99m tetrofosmin passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 20:27 Last Updated: September 21, 2023 at 20:27
PW146025 View Pathway	drug action Technetium Tc-99m tetrofosmin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:14 Last Updated: October 07, 2023 at 17:14
PW146057 View Pathway	drug action Technetium Tc-99m tilmanocept Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:18 Last Updated: October 07, 2023 at 17:18
PW127608 View Pathway	drug action Tecovirimat Action Pathway Homo sapiens Tecovirimat (Tpoxx) is an antiviral used in the treatment of smallpox, monkeypox and cowpox. In fact, this drug is effective against all orthopoxviruses, including vaccinia, cowpox, ectromelia, rabbitpox, monkeypox and variola virus (smallpox). Tecovirimat was approved by the FDA in July 2018. Tecovirimal is an inhibitor of the P37 protein (VP37 envelope-wrapping protein)) of the orthopoxvirus. This protein is essential to form the wrapping complex of mature virions with late endosomal membranes by interacting with proteins such as Rab9 GTPase and TIP47.. The P37 protein is encoded by a highly conserved gene in all members of the orthopoxvirus genus. When Tecovirimat binds P37, this protein can not interact with the Rab9 GTPase and TIP47, which are components of late endosome-derived transport vesicles. In consequence, there is no formation of the wrapping complex for enveloped virions. This drug is available as an oral tablet and an intravenous formulation. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: May 15, 2023 at 12:12 Last Updated: May 15, 2023 at 12:12