PathWhiz

PathWhiz ID	Pathway	Meta Data
PW000188 View Pathway	disease UMP Synthase Deficiency (Orotic Aciduria) Homo sapiens Orotic aciduria, also known as UMP synthase deficiency, is an autosomal recessive disorder of pyrimidine metabolism caused by a defective uridine monophosphate synthetase (UMPS). UMPS is a multifunctional protein which carries out the functions of both orotate phosphoribosyltransferase (OPRT) and orotidine 5'-phosphate decarboxylase (ODC). UMPS catalyzes the conversion of orotic acid into uridine monophosphate (UMP) which is a nucleotide incorporated into ribonucleic acid (RNA). This disease is characterized by a very large accumulation of orotic acid in the urine, occasionally causing urinary obstruction. Symptoms of the disease include megaloblastic anemia as well as retarded growth and development. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: August 19, 2013 at 12:05 Last Updated: August 19, 2013 at 12:05
PW127284 View Pathway	disease UMP Synthase Deficiency (Orotic Aciduria) Homo sapiens Orotic aciduria, also known as UMP synthase deficiency, is an autosomal recessive disorder of pyrimidine metabolism caused by a defective uridine monophosphate synthetase (UMPS). UMPS is a multifunctional protein which carries out the functions of both orotate phosphoribosyltransferase (OPRT) and orotidine 5'-phosphate decarboxylase (ODC). UMPS catalyzes the conversion of orotic acid into uridine monophosphate (UMP) which is a nucleotide incorporated into ribonucleic acid (RNA). This disease is characterized by a very large accumulation of orotic acid in the urine, occasionally causing urinary obstruction. Symptoms of the disease include megaloblastic anemia as well as retarded growth and development. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: November 29, 2022 at 16:03 Last Updated: November 29, 2022 at 16:03
PW132278 View Pathway	metabolic Undecoylium chloride iodine complex Drug Metabolism Homo sapiens Undecoylium chloride iodine complex is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Undecoylium chloride iodine complex passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 20:35 Last Updated: September 21, 2023 at 20:35
PW146123 View Pathway	drug action Undecoylium chloride iodine complex Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:28 Last Updated: October 07, 2023 at 17:28
PW146241 View Pathway	drug action Undecylenic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:45 Last Updated: October 07, 2023 at 17:45
PW123869 View Pathway	metabolic Unico ajajaj Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Johann Created On: April 24, 2020 at 15:38 Last Updated: April 24, 2020 at 15:38
PW145826 View Pathway	drug action Unoprostone Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:45 Last Updated: October 07, 2023 at 16:45
PW132444 View Pathway	metabolic Upadacitinib Drug Metabolism Homo sapiens Upadacitinib is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Upadacitinib passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 21:49 Last Updated: September 21, 2023 at 21:49
PW146906 View Pathway	drug action Upadacitinib Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 19:19 Last Updated: October 07, 2023 at 19:19
PW123957 View Pathway	signaling UPR Mus musculus UPR BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: July 03, 2020 at 15:45 Last Updated: July 03, 2020 at 15:45