PathWhiz

PathWhiz ID	Pathway	Meta Data
PW145888 View Pathway	drug action Radium Ra 223 dichloride Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:54 Last Updated: October 07, 2023 at 16:54
PW122522 View Pathway	disease RAGE Signalling Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Abu Sufiyan Chhipa Created On: June 06, 2019 at 05:33 Last Updated: June 06, 2019 at 05:33
PW144603 View Pathway	drug action Raloxifene Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:00 Last Updated: October 07, 2023 at 14:00
PW127483 View Pathway	drug action Raltegravir Action Pathway Homo sapiens Raltegravir is an antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals. Raltegravir is transported into the infected cell then transported into the nucleus via importin nuclear transporter.The viral RNA is injected into the cell then transcribed into viral DNA via reverse transcriptase. It is then transported into the nucleus where it is integrated into the host DNA. Raltegravir inhibits HIV integrase which prevents the viral DNA from being integrated into the host DNA. This prevents viral replication and further progression of the virus. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: March 15, 2023 at 11:37 Last Updated: March 15, 2023 at 11:37
PW132514 View Pathway	metabolic Raltegravir Drug Metabolism Homo sapiens Raltegravir is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Raltegravir passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 22:12 Last Updated: September 21, 2023 at 22:12
PW145818 View Pathway	drug action Raltegravir Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:44 Last Updated: October 07, 2023 at 16:44
PW127897 View Pathway	drug action Raltitrexed Action Pathway Homo sapiens Raltitrexed is a folate analog that is used in the treatment of colorectal cancer, that is an inhibitor of thymidylate synthase. Inhibiting thymidylate synthase stops the proliferation of cancer cells, as it stops the production and formation of purines and pyrimidines needed for DNA replication. Once transported into the cells through a reduced folate carrier it is polyglutamated by folylpolyglutamate synthetase to further enhance the inhibitory action. There are some side effects that may occur such as pale skin, trouble breathing, bleeding, bruising, fatigue, chest pains, chills, cough, fever and issues with gastrointestinal issues. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Selena Created On: June 16, 2023 at 11:22 Last Updated: June 16, 2023 at 11:22
PW144421 View Pathway	drug action Raltitrexed Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:36 Last Updated: October 07, 2023 at 13:36
PW132531 View Pathway	metabolic Ramelteon Drug Metabolism Homo sapiens Ramelteon is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Ramelteon passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 22:17 Last Updated: September 21, 2023 at 22:17
PW145078 View Pathway	drug action Ramelteon Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:02 Last Updated: October 07, 2023 at 15:02