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Pathways

PathWhiz ID Pathway Meta Data

PW122494

Pw122494 View Pathway
metabolic

Selenocompound Metabolism

Xenopus laevis

PW075771

Pw075771 View Pathway
metabolic

Selenocompound Metabolism

Homo sapiens
Selenate is the major inorganic selenocompound found in both animal and plant tissues. Selenocysteine is the predominant selenoamino acid in tissues when inorganic selenium is given to animals. Selenomethionine is the major selenocompound found initially in animals given this selenoamino acid, but is converted with time afterwards to selenocysteine. Selenomethionine is the major selenocompound in cereal grains, grassland legumes and soybeans. Selenomethionine can also be the major selenocompound in selenium enriched yeast, but the amount can vary markedly depending upon the growth conditions.

PW146261

Pw146261 View Pathway
drug action

Selenomethionine Drug Metabolism Action Pathway

Homo sapiens

PW146137

Pw146137 View Pathway
drug action

Selenomethionine Se-75 Drug Metabolism Action Pathway

Homo sapiens

PW128107

Pw128107 View Pathway
drug action

Selexipag Action Pathway

Homo sapiens
Selexipag is a non-prostanoid prostacyclin receptor agonist, also known as Uptravi typically used to treat pulmonary arterial hypertension. Selexipag is a selective prostacyclin receptor agonist, it is administered orally and is metabolized by carboylesterase1 into its active metabolite (ACT-333679). The metabolite has a high selectivity for prostacyclin receptor that activates it and subsequent G coupled protein, Gs, that increases cAMP levels. Increased cAMP levels leads to inhibited platelet aggregation and activation.

PW146368

Pw146368 View Pathway
drug action

Selexipag Drug Metabolism Action Pathway

Homo sapiens

PW132448

Pw132448 View Pathway
metabolic

Selinexor Drug Metabolism

Homo sapiens
Selinexor is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Selinexor passes through the liver and is then excreted from the body mainly through the kidney.

PW146472

Pw146472 View Pathway
drug action

Selinexor Drug Metabolism Action Pathway

Homo sapiens

PW146936

Pw146936 View Pathway
drug action

Selpercatinib Drug Metabolism Action Pathway

Homo sapiens

PW146426

Pw146426 View Pathway
drug action

Selumetinib Drug Metabolism Action Pathway

Homo sapiens