
PathWhiz ID | Pathway | Meta Data |
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PW000038 |
Taurine and Hypotaurine MetabolismHomo sapiens
There is an organic acid known as Taurine, which is a derivative product of sulfhydryl amino acid (which contains sulfur), as well as cysteine. The synthesis or metabolism in mammalian systems of this acid transpires within the pancreas in such a fashion that it utilizes a pathway known as the cysteine sulfinic acid pathway.
To put this process in context, its occurrence is often seen in vivo, in hepatocytes, and is fundamental in the cyclical process of recovering bile acids from the intenstine, turning them back into salts and returning them to the bile.
In essence the cysteine pathway induces a sulfhydryl group to be oxidized, creating cysteine sulfinic acid, by utilizing the appropriate enzymes (ie cysteine dioxygenase). This new acid undergoes decarboxylation creating a new compound: hypotaurine. This process goes on as Taurine now is subjected to conjugation vis a vis its amino terminal group. This includes acids such as chenodeoxycholic acid and cholic acid, and in turn the formation of bile salts occurs.
Moreover, this entire process can be catalyzed via bile acid and a special amino acid N-acetyltransferase.
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Creator: WishartLab Created On: August 01, 2013 at 13:54 Last Updated: August 01, 2013 at 13:54 |
PW145503 |
drug action
Taurine Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 15:57 Last Updated: October 07, 2023 at 15:57 |
PW392234 |
Taurine MetabolismEscherichia coli 536
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 13, 2024 at 22:16 Last Updated: December 13, 2024 at 22:16 |
PW392239 |
Taurine MetabolismEscherichia coli APEC O1
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 13, 2024 at 22:19 Last Updated: December 13, 2024 at 22:19 |
PW392258 |
Taurine MetabolismEscherichia coli HS
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 13, 2024 at 22:26 Last Updated: December 13, 2024 at 22:26 |
PW390283 |
Taurine MetabolismHalococcus morrhuae DSM 1307
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 12, 2024 at 14:17 Last Updated: December 12, 2024 at 14:17 |
PW387944 |
Taurine MetabolismParabacteroides goldsteinii dnLKV18
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 11, 2024 at 16:06 Last Updated: December 11, 2024 at 16:06 |
PW389642 |
Taurine MetabolismNeisseria elongata subsp. glycolytica ATCC 29315
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 12, 2024 at 07:34 Last Updated: December 12, 2024 at 07:34 |
PW389700 |
Taurine MetabolismCampylobacter gracilis RM3268
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 12, 2024 at 08:17 Last Updated: December 12, 2024 at 08:17 |
PW389995 |
Taurine MetabolismHaemophilus sputorum CCUG 13788
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.
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Creator: Julia Wakoli Created On: December 12, 2024 at 11:26 Last Updated: December 12, 2024 at 11:26 |