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Pathways

PathWhiz ID Pathway Meta Data

PW000038

Pw000038 View Pathway
metabolic

Taurine and Hypotaurine Metabolism

Homo sapiens
There is an organic acid known as Taurine, which is a derivative product of sulfhydryl amino acid (which contains sulfur), as well as cysteine. The synthesis or metabolism in mammalian systems of this acid transpires within the pancreas in such a fashion that it utilizes a pathway known as the cysteine sulfinic acid pathway. To put this process in context, its occurrence is often seen in vivo, in hepatocytes, and is fundamental in the cyclical process of recovering bile acids from the intenstine, turning them back into salts and returning them to the bile. In essence the cysteine pathway induces a sulfhydryl group to be oxidized, creating cysteine sulfinic acid, by utilizing the appropriate enzymes (ie cysteine dioxygenase). This new acid undergoes decarboxylation creating a new compound: hypotaurine. This process goes on as Taurine now is subjected to conjugation vis a vis its amino terminal group. This includes acids such as chenodeoxycholic acid and cholic acid, and in turn the formation of bile salts occurs. Moreover, this entire process can be catalyzed via bile acid and a special amino acid N-acetyltransferase.

PW145503

Pw145503 View Pathway
drug action

Taurine Drug Metabolism Action Pathway

Homo sapiens

PW392234

Pw392234 View Pathway
metabolic

Taurine Metabolism

Escherichia coli 536
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.

PW392239

Pw392239 View Pathway
metabolic

Taurine Metabolism

Escherichia coli APEC O1
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.

PW392258

Pw392258 View Pathway
metabolic

Taurine Metabolism

Escherichia coli HS
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.

PW390283

Pw390283 View Pathway
metabolic

Taurine Metabolism

Halococcus morrhuae DSM 1307
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.

PW387944

Pw387944 View Pathway
metabolic

Taurine Metabolism

Parabacteroides goldsteinii dnLKV18
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.

PW389642

Pw389642 View Pathway
metabolic

Taurine Metabolism

Neisseria elongata subsp. glycolytica ATCC 29315
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.

PW389700

Pw389700 View Pathway
metabolic

Taurine Metabolism

Campylobacter gracilis RM3268
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.

PW389995

Pw389995 View Pathway
metabolic

Taurine Metabolism

Haemophilus sputorum CCUG 13788
Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide.