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PW386029

Pw386029 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Escherichia coli (strain ATCC 55124 / KO11)
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 16:41

Last Updated: December 10, 2024 at 16:41

PW684275

Pw684275 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Halococcus morrhuae DSM 1307
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 09:31

Last Updated: December 10, 2024 at 09:31

PW385139

Pw385139 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

[Bacteroides] pectinophilus ATCC 43243
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 09:19

Last Updated: December 10, 2024 at 09:19

PW385109

Pw385109 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Vibrio fluvialis PG41
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 08:53

Last Updated: December 10, 2024 at 08:53

PW385133

Pw385133 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Subdoligranulum variabile DSM 15176
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 09:14

Last Updated: December 10, 2024 at 09:14

PW384749

Pw384749 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Megasphaera elsdenii DSM 20460
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 03:40

Last Updated: December 10, 2024 at 03:40

PW684239

Pw684239 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Bacteroides finegoldii DSM 17565
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 04:35

Last Updated: December 10, 2024 at 04:35

PW684241

Pw684241 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Bacteroides xylanisolvens SD CC 1b
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 04:52

Last Updated: December 10, 2024 at 04:52

PW684238

Pw684238 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Bacteroides fluxus YIT 12057
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 04:35

Last Updated: December 10, 2024 at 04:35

PW384843

Pw384843 View Pathway
metabolic

Biosynthesis of Siderophore Group Nonribosomal Peptides

Bacteroides sp. 2_2_4
2,3-Dihydroxybenzoate is created from chorismate through isochorismate and 2,3-dihydroxy-2,3-dihydrobenzoate. The biosynthesis of 2,3-dihydroxybenzoate starts from chorismate being converted into isochorismate through isochorismate synthase entC. The N-terminal isochorismate lyase domain of EntB adds hydrogen to the pyruvate group of isochorismate to create 2,3-dihydro-2,3-dihydroxybenzoate. this latter compound to 2,3-dihydroxybenzoate is then converted by the catalyzation of EntA dehydrogenase. This compound then interacts with L-serine and ATP through the enterobactin synthase protein complex resulting in the production of enterobactin. Enterobactin is exported into the periplasmic space through the enterobactin exporter entS. Enterobactin is then exported into the environment through the outer membrane protein TolC. In the environment, enterobactin reacts with iron to produce ferric enterobactin. It is then imported into the periplasmic space through a ferric enterobactin outer membrane transport complex. Ferric enterobactin continues it's journey and enters the cytoplasm via a ferric enterobactin ABC transporter. Once inside the cytoplasm, ferric enterobactin spontaneously releases the iron ion from the enterobactin. Alternatively, it can react with water through an enterochelin esterase resulting in the release of 2,3-dihydroxybenzoylserine, Fe3+, and hydrogen ions.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 10, 2024 at 04:57

Last Updated: December 10, 2024 at 04:57