PathWhiz

PathWhiz ID	Pathway	Meta Data
PW501115 View Pathway	metabolic Adenine and Adenosine Salvage I Citrobacter amalonaticus Y19 The salvage of adenine begins with adenine being transporter into the cytosol through a adeP hydrogen symporter. Once in the cytosol adenine is degraded by reacting with a ribose-1-phosphate through an adenosine phosphorylase resulting in the release of a phosphate and adenosine. Adenosine is then deaminated by reacting with water, a hydrogen ion and an adenosine deaminase resulting in the release of an ammonium and a inosine . Inosine then reacts with a phosphate through a inosine phosphorylase resulting in the release of a ribose 1-phosphate and a hypoxanthine. Hypoxanthine reacts with a PRPP through a hypoxanthine phosphoribosyltransferase resulting in the release of a pyrophosphate and a IMP molecule. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 05, 2025 at 10:49 Last Updated: February 05, 2025 at 10:49
PW498730 View Pathway	metabolic Adenine and Adenosine Salvage I Bacteroides caccae ATCC 43185 The salvage of adenine begins with adenine being transporter into the cytosol through a adeP hydrogen symporter. Once in the cytosol adenine is degraded by reacting with a ribose-1-phosphate through an adenosine phosphorylase resulting in the release of a phosphate and adenosine. Adenosine is then deaminated by reacting with water, a hydrogen ion and an adenosine deaminase resulting in the release of an ammonium and a inosine . Inosine then reacts with a phosphate through a inosine phosphorylase resulting in the release of a ribose 1-phosphate and a hypoxanthine. Hypoxanthine reacts with a PRPP through a hypoxanthine phosphoribosyltransferase resulting in the release of a pyrophosphate and a IMP molecule. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 04, 2025 at 15:03 Last Updated: February 04, 2025 at 15:03
PW686122 View Pathway	metabolic Adenine and Adenosine Salvage I Bacteroides sp. D20 The salvage of adenine begins with adenine being transporter into the cytosol through a adeP hydrogen symporter. Once in the cytosol adenine is degraded by reacting with a ribose-1-phosphate through an adenosine phosphorylase resulting in the release of a phosphate and adenosine. Adenosine is then deaminated by reacting with water, a hydrogen ion and an adenosine deaminase resulting in the release of an ammonium and a inosine . Inosine then reacts with a phosphate through a inosine phosphorylase resulting in the release of a ribose 1-phosphate and a hypoxanthine. Hypoxanthine reacts with a PRPP through a hypoxanthine phosphoribosyltransferase resulting in the release of a pyrophosphate and a IMP molecule. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 04, 2025 at 19:47 Last Updated: February 04, 2025 at 19:47
PW499531 View Pathway	metabolic Adenine and Adenosine Salvage I Odoribacter laneus YIT 12061 The salvage of adenine begins with adenine being transporter into the cytosol through a adeP hydrogen symporter. Once in the cytosol adenine is degraded by reacting with a ribose-1-phosphate through an adenosine phosphorylase resulting in the release of a phosphate and adenosine. Adenosine is then deaminated by reacting with water, a hydrogen ion and an adenosine deaminase resulting in the release of an ammonium and a inosine . Inosine then reacts with a phosphate through a inosine phosphorylase resulting in the release of a ribose 1-phosphate and a hypoxanthine. Hypoxanthine reacts with a PRPP through a hypoxanthine phosphoribosyltransferase resulting in the release of a pyrophosphate and a IMP molecule. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 04, 2025 at 20:20 Last Updated: February 04, 2025 at 20:20
PW498944 View Pathway	metabolic Adenine and Adenosine Salvage I Bacteroides fluxus YIT 12057 The salvage of adenine begins with adenine being transporter into the cytosol through a adeP hydrogen symporter. Once in the cytosol adenine is degraded by reacting with a ribose-1-phosphate through an adenosine phosphorylase resulting in the release of a phosphate and adenosine. Adenosine is then deaminated by reacting with water, a hydrogen ion and an adenosine deaminase resulting in the release of an ammonium and a inosine . Inosine then reacts with a phosphate through a inosine phosphorylase resulting in the release of a ribose 1-phosphate and a hypoxanthine. Hypoxanthine reacts with a PRPP through a hypoxanthine phosphoribosyltransferase resulting in the release of a pyrophosphate and a IMP molecule. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 04, 2025 at 16:29 Last Updated: February 04, 2025 at 16:29
PW495692 View Pathway	metabolic Adenine and Adenosine Salvage I Escherichia coli (strain K12 / MC4100 / BW2952) The salvage of adenine begins with adenine being transporter into the cytosol through a adeP hydrogen symporter. Once in the cytosol adenine is degraded by reacting with a ribose-1-phosphate through an adenosine phosphorylase resulting in the release of a phosphate and adenosine. Adenosine is then deaminated by reacting with water, a hydrogen ion and an adenosine deaminase resulting in the release of an ammonium and a inosine . Inosine then reacts with a phosphate through a inosine phosphorylase resulting in the release of a ribose 1-phosphate and a hypoxanthine. Hypoxanthine reacts with a PRPP through a hypoxanthine phosphoribosyltransferase resulting in the release of a pyrophosphate and a IMP molecule. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 03, 2025 at 13:39 Last Updated: February 03, 2025 at 13:39
PW686065 View Pathway	metabolic Adenine and Adenosine Salvage I Escherichia coli (strain ATCC 55124 / KO11) The salvage of adenine begins with adenine being transporter into the cytosol through a adeP hydrogen symporter. Once in the cytosol adenine is degraded by reacting with a ribose-1-phosphate through an adenosine phosphorylase resulting in the release of a phosphate and adenosine. Adenosine is then deaminated by reacting with water, a hydrogen ion and an adenosine deaminase resulting in the release of an ammonium and a inosine . Inosine then reacts with a phosphate through a inosine phosphorylase resulting in the release of a ribose 1-phosphate and a hypoxanthine. Hypoxanthine reacts with a PRPP through a hypoxanthine phosphoribosyltransferase resulting in the release of a pyrophosphate and a IMP molecule. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 03, 2025 at 14:15 Last Updated: February 03, 2025 at 14:15
PW144264 View Pathway	drug action Ademetionine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:03 Last Updated: October 07, 2023 at 13:03
PW000605 View Pathway	drug metabolism Adefovir Dipivoxil Metabolism Pathway Homo sapiens Adefovir dipivoxil is an ester prodrug of adefovir, a nucleotide analogue used in the treatment of chronic hepatitis B. Adefovir dipivoxil is taken up into the liver cell and is cleaved into adefovir by intracellular esterases. Adefovir is subsequently phosphorylated first by adenylate kinases and then by nucleoside diphosphate kinases into adefovir diphosphate. Adefovir diphosphate is an analogue of deoxyadenosine triphosphate (dATP) and competes with dATP for binding to the viral DNA polymerase and subsequent incorporation into the growing DNA strand. Once incorporated into the DNA, adefovir causes chain termination, thus preventing viral replication. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: September 11, 2013 at 22:33 Last Updated: September 11, 2013 at 22:33
PW144830 View Pathway	drug action Adefovir dipivoxil Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:31 Last Updated: October 07, 2023 at 14:31