PathWhiz

PathWhiz ID	Pathway	Meta Data
PW457262 View Pathway	metabolic PRPP Biosynthesis Veillonella atypica ACS-049-V-Sch6 The biosynthesis of phosphoribosyl pyrophosphate begins as a product of the pentose phosphate and D-ribose 5-phosphate interaction. When catalyzed with a phosphopentomutase, the product is a ribose 1-phosphate. Ribose 1-phosphate can interact spontaneously with ATP resulting in a release of hydrogen ion, ADP and a ribose 1,5-biphosphate. Ribose 1,5-biphosphate is then phosphorylated through a ribose 1,5-bisphosphokinase resulting in the release of ADP and phosphoribosyl pyrophosphate. Phosphoribosyl pyrophosphate will then participate in the purine nucleotides de novo biosynthesis pathway. Alternatively pentose phosphate and D-ribose 5-phosphate's interaction can be phosphorylated through an ATP driven ribose-phosphate diphosphokinase resulting in a release of a hydrogen ion, an AMP and a phosphoribosyl pyrophosphate which will again participate in the purine nucleotides de novo biosynthesis pathway. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: January 17, 2025 at 10:41 Last Updated: January 17, 2025 at 10:41
PW146622 View Pathway	drug action Proxibarbal Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 18:39 Last Updated: October 07, 2023 at 18:39
PW132492 View Pathway	metabolic Proxibarbal Drug Metabolism Homo sapiens Proxibarbal is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Proxibarbal passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 22:04 Last Updated: September 21, 2023 at 22:04
PW176124 View Pathway	metabolic Protriptyline Predicted Metabolism Pathway new Homo sapiens Metabolites of Protriptyline are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 14:08 Last Updated: November 29, 2023 at 14:08
PW144470 View Pathway	drug action Protriptyline Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:42 Last Updated: October 07, 2023 at 13:42
PW145815 View Pathway	drug action Protokylol Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:44 Last Updated: October 07, 2023 at 16:44
PW064773 View Pathway	signaling Protocadherin Fat 1 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: June 20, 2018 at 03:13 Last Updated: June 20, 2018 at 03:13
PW146150 View Pathway	drug action Protirelin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:31 Last Updated: October 07, 2023 at 17:31
PW146548 View Pathway	drug action Protionamide Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 18:28 Last Updated: October 07, 2023 at 18:28
PW120704 View Pathway	protein Protein Synthesis: Valine Rattus norvegicus Protein synthesis is an essential life process that builds the important large amino acid macromolecules that function as enzymes, antibodies, and cellular structural components. Although synthesis begins with the transcription of DNA into RNA, this pathway depicts the reactions that occur during translation. Transcribed messenger RNA (mRNA), which contains the genetic code to direct protein synthesis, is transported out of the nucleus and becomes bound to ribosomes in the cytoplasm or endoplasmic reticulum. The amino acids required to assemble polypeptide chains are delivered to the ribosomes using transfer RNA (tRNA). Each tRNA molecule has both a binding site for a specific amino acid and a three-nucleotide sequence called the anticodon that forms three complementary base pairs with an mRNA codon. Charging or loading the appropriate amino acid onto its tRNA is carried out by an aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase. This enzyme catalyzes the esterification of an amino acid to one of all its compatible tRNAs to form an aminoacyl-tRNA. Each of the twenty amino acids has a corresponding aa-tRNA made by a specific aminoacyl-tRNA synthetase. Ribosomes match the anticodons of the charged tRNA molecules with successive codons of the mRNA. After a match is found, the ribosome transfers the amino acid from the matching tRNA onto the growing peptide chain via a reaction termed peptide condensation, and the tRNAs, no longer carrying amino acids, are released. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Carin Li Created On: September 10, 2018 at 14:54 Last Updated: September 10, 2018 at 14:54