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9606 TAXONOMY 962 PubChem-compound Solute carrier family 2, facilitated glucose transporter member 2 923 PubChem-compound P11168 UniProt 937 ChemSpider C00031 KEGG Compound Transport191 false D-Glucose (→) Transport: Homo sapiens, Blood Vessel to Homo sapiens, Liver, Cell LEFT_TO_RIGHT P13866 UniProt 1.0 899 ChemSpider 76293 ChemSpider HMDB02111 HMDB Sodium ReactionCatalysis1202 ACTIVATION Water 439357 PubChem-compound 63-42-3 CAS LACTOSE BioCyc TransportCatalysis95 ACTIVATION CHEBI:36219 ChEBI SMILES O TransportCatalysis94 ACTIVATION C6H12O6 D-Glucose 180.06339 P09848 UniProt D-Galactose SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O CHEBI:15377 ChEBI Transport121 false D-Glucose (→), Sodium (→) Transport: Homo sapiens, Intestine to Homo sapiens, Intestine, Epithelial Cell LEFT_TO_RIGHT Lactose Degradation C12H22O11 Alpha-Lactose 342.1162 Transport122 false D-Galactose (→), Sodium (→) Transport: Homo sapiens, Intestine to Homo sapiens, Intestine, Epithelial Cell LEFT_TO_RIGHT Lactose Synthesis SubPathway HMDB00588 HMDB C00243 KEGG Compound C00001 KEGG Compound GLC BioCyc Sodium/glucose cotransporter 1 SMILES [Na+] 388480 ChemSpider C01330 KEGG Compound Lactase-phlorizin hydrolase HMDB00186 HMDB HMDB00143 HMDB 1.0 Reaction1481 false Alpha-Lactose + Water → D-Galactose + D-Glucose LEFT_TO_RIGHT Intestine CHEBI:4167 ChEBI Lactase-phlorizin hydrolase 17341-25-2 CAS TransportCatalysis143 ACTIVATION 5793 PubChem-compound TransportCatalysis142 ACTIVATION 84571 PubChem-compound GALACTOSE BioCyc 5589 ChemSpider Sodium/glucose cotransporter 1 PW000049 PathWhiz CHEBI:28061 ChEBI 7732-18-5 CAS Alpha-Lactose SubPathwayOutput SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O C6H12O6 D-Galactose 180.06339 2280-44-6 CAS H2O Water 18.010565 D-Glucose BTO:0000648 BRENDA TISSUE ONTOLOGY SMP00444 SMPDB HMDB00122 HMDB Transport187 false D-Glucose (→) Transport: Homo sapiens, Intestine, Epithelial Cell to Homo sapiens, Blood Vessel LEFT_TO_RIGHT PW000153 PathWhiz 1.0 Transport188 false D-Galactose (→) Transport: Homo sapiens, Intestine, Epithelial Cell to Homo sapiens, Blood Vessel LEFT_TO_RIGHT Na Sodium 22.989769 SMP00457 SMPDB 1.0 59-23-4 CAS SubPathwayInteraction649 SubPathwayReaction SubPathway649Reaction C00984 KEGG Compound Solute carrier family 2, facilitated glucose transporter member 2 SMILES OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O 1.0 BiologicalState60 CHEBI:29101 ChEBI Sodium/glucose cotransporter 1 Sodium/glucose cotransporter 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Lactase- phlorizin hydrolase Sodium/potassium- transporting ATPase subunit alpha-1 Alpha-Lactose D-Glucose D-Glucose Na + Na + D-Galactose D-Galactose Na + Na + D-Galactose D-Glucose D-Glucose H 2 O ATP K + Na + ADP K + Lactose Synthesis Intestinal microvillus Intestinal Epithelial Cell Intestinal Epithelial Cell Capillary Bed Lacteal Intestinal Epithelial Cell Capillary Capillary Bed Liver Intestinal Lumen
9606 TAXONOMY 962 PubChem-compound Solute carrier family 2, facilitated glucose transporter member 2 923 PubChem-compound P11168 UniProt 937 ChemSpider C00031 KEGG Compound Transport191 false D-Glucose (→) Transport: Homo sapiens, Blood Vessel to Homo sapiens, Liver, Cell LEFT_TO_RIGHT P13866 UniProt 1.0 899 ChemSpider 76293 ChemSpider HMDB02111 HMDB Sodium ReactionCatalysis1202 ACTIVATION Water 439357 PubChem-compound 63-42-3 CAS LACTOSE BioCyc TransportCatalysis95 ACTIVATION CHEBI:36219 ChEBI SMILES O TransportCatalysis94 ACTIVATION C6H12O6 D-Glucose 180.06339 P09848 UniProt D-Galactose SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O CHEBI:15377 ChEBI Transport121 false D-Glucose (→), Sodium (→) Transport: Homo sapiens, Intestine to Homo sapiens, Intestine, Epithelial Cell LEFT_TO_RIGHT Lactose Degradation C12H22O11 Alpha-Lactose 342.1162 Transport122 false D-Galactose (→), Sodium (→) Transport: Homo sapiens, Intestine to Homo sapiens, Intestine, Epithelial Cell LEFT_TO_RIGHT Lactose Synthesis SubPathway HMDB00588 HMDB C00243 KEGG Compound C00001 KEGG Compound GLC BioCyc Sodium/glucose cotransporter 1 SMILES [Na+] 388480 ChemSpider C01330 KEGG Compound Lactase-phlorizin hydrolase HMDB00186 HMDB HMDB00143 HMDB 1.0 Reaction1481 false Alpha-Lactose + Water → D-Galactose + D-Glucose LEFT_TO_RIGHT Intestine CHEBI:4167 ChEBI Lactase-phlorizin hydrolase 17341-25-2 CAS TransportCatalysis143 ACTIVATION 5793 PubChem-compound TransportCatalysis142 ACTIVATION 84571 PubChem-compound GALACTOSE BioCyc 5589 ChemSpider Sodium/glucose cotransporter 1 PW000049 PathWhiz CHEBI:28061 ChEBI 7732-18-5 CAS Alpha-Lactose SubPathwayOutput SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O C6H12O6 D-Galactose 180.06339 2280-44-6 CAS H2O Water 18.010565 D-Glucose BTO:0000648 BRENDA TISSUE ONTOLOGY http://identifiers.org/smpdb/SMP00444 SMPDB HMDB00122 HMDB Transport187 false D-Glucose (→) Transport: Homo sapiens, Intestine, Epithelial Cell to Homo sapiens, Blood Vessel LEFT_TO_RIGHT PW000153 PathWhiz 1.0 Transport188 false D-Galactose (→) Transport: Homo sapiens, Intestine, Epithelial Cell to Homo sapiens, Blood Vessel LEFT_TO_RIGHT Na Sodium 22.989769 http://identifiers.org/smpdb/SMP00457 SMPDB 1.0 59-23-4 CAS SubPathwayInteraction649 SubPathwayReaction SubPathway649Reaction C00984 KEGG Compound Solute carrier family 2, facilitated glucose transporter member 2 SMILES OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O 1.0 BiologicalState60 Homo sapiens, Intestine CHEBI:29101 ChEBI SLC5A1 SLC5A1 SLC2A2 SLC2A2 LCT ATP1A1 Alpha-Lactose D-Glucose D-Glucose Sodium Sodium D-Galactose D-Galactose Sodium Sodium D-Galactose D-Glucose D-Glucose Water Adenosine triphosphate Potassium Sodium Adenosine diphosphate Potassium Lactose Synthesis