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Pathway Description
Pancreas Function
Homo sapiens
Physiological Pathway
The pancreas is crucial in many organisms for properly converting food into usable fuel to be used by cells. It acts as part of the digestive system for a majority of its function as it is connected to the stomach and provides digestive enzymes to the partly digested food brought in by the stomach. The pancreas also serves as an endocrine component, by creating hormones to regulate blood sugar. Insulin, a hormone created by the pancreas (beta cells), acts to lower blood sugar, which is very important as it allows cells in the body to use sugar without inducing hyperglycaemia.
References
Pancreas Function References
Roder PV, Wu B, Liu Y, Han W: Pancreatic regulation of glucose homeostasis. Exp Mol Med. 2016 Mar 11;48:e219. doi: 10.1038/emm.2016.6.
Pubmed: 26964835
Gaisano HY, Macdonald PE, Vranic M: Glucagon secretion and signaling in the development of diabetes. Front Physiol. 2012 Sep 4;3:349. doi: 10.3389/fphys.2012.00349. eCollection 2012.
Pubmed: 22969729
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