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CHEBI:16015 ChEBI 30572 ChemSpider 1.0 7722-84-1 CAS C4H4O5 Oxalacetic acid 132.00587 adenylosuccinate synthase 937 ChemSpider aspartate ammonia-lyase aspartate carbamoyltransferase argininosuccinate synthase 6267 PubChem-compound CHEBI:16134 ChEBI asparagine synthetase II HMDB0003125 HMDB Adenosine monophosphate 1.0 110-17-8 CAS 21883788 PubChem-compound HMDB0000536 HMDB SMILES O SMILES OO C10H18N4O6 Argininosuccinic acid 290.12262 H3N Ammonia 17.026548 C6H14N4O2 L-Arginine 174.11168 C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate 50 ChemSpider C00327 KEGG Compound CHEBI:16027 ChEBI P0AC38 UniProt 6992098 PubChem-compound C5H6N2O5 N-carbamoyl-L-aspartate 174.02876 HMDB0000538 HMDB 6.0 OXALACETIC_ACID BioCyc 1.0 ATP BioCyc 5961 PubChem-compound Citrulline 1.0 1.0 328-42-7 CAS 1.0 131-99-7 CAS 51 PubChem-compound 559142 ChemSpider 2.0 ReactionCatalysis2660 ACTIVATION 1.0 CHEBI:17202 ChEBI NAD Biosynthesis SubPathway 8582 PubChem-compound 5746 ChemSpider 5745 ChemSpider 5742 ChemSpider ASN BioCyc Argininosuccinate synthase Argininosuccinic acid 1.0 L-ASPARTATE BioCyc 952 ChemSpider Aspartate carbamoyltransferase catalytic chain GO:0005829 GENE ONTOLOGY Ammonia L-Arginine Adenosine monophosphate C5H6O5 Oxoglutaric acid 146.02153 5858 ChemSpider ARG BioCyc 1.0 Ammonia Aspartate aminotransferase L-CITRULLINE BioCyc Pyrophosphate O4P Phosphate 94.95342 Oxalacetic acid CHEBI:16240 ChEBI 945 ChemSpider 6830 PubChem-compound 16950 PubChem-compound C10H15N5O11P2 Guanosine diphosphate 443.02432 6031 ChemSpider 1.0 PW000829 PathWhiz PPI BioCyc Adenylosuccinate synthetase 21960964 PubChem-compound 1.0 P0A6E4 UniProt P11447 UniProt adenylosuccinate lyase 2 PW000787 PathWhiz C10H16N5O14P3 Guanosine triphosphate 522.99066 1.0 Fumaric acid C5H10N2O3 L-Glutamine 146.06914 Aspartate--ammonia ligase Adenylsuccinic acid HMDB0000208 HMDB Cytosol CPD-6641 BioCyc 1.0 217 ChemSpider SMP0000849 SMPDB Adenosine triphosphate P22106 UniProt L-Glutamic acid Aspartate carbamoyltransferase regulatory chain SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O Oxygen CHEBI:30915 ChEBI PW000779 PathWhiz C00009 KEGG Compound C00007 KEGG Compound beta-Alanine Metabolism SubPathway 1.0 PW000896 PathWhiz C00001 KEGG Compound C00122 KEGG Compound HMDB0001429 HMDB 19046-78-7 CAS CHEBI:18361 ChEBI SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 CHEBI:18367 ChEBI 1032 ChemSpider aspartate transaminase 1.0 C00002 KEGG Compound HMDB0000223 HMDB GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc Fumaric acid GLN BioCyc GLT BioCyc 7664-41-7 CAS C4H4O4 Fumaric acid 116.010956 6.0 Aspartate Metabolism 1.0 N-carbamoyl-L-aspartate Aspartate--ammonia ligase C6H13N3O3 Citrulline 175.09569 Oxoglutaric acid 372-75-8 CAS C03406 KEGG Compound 44367445 PubChem-compound 1.0 4.0 TCA Cycle SubPathway C00130 KEGG Compound 222 PubChem-compound HMDB0000904 HMDB C00014 KEGG Compound C00013 KEGG Compound 4.0 SMILES N[C@@H](CC(N)=O)C(O)=O 8264 ChemSpider HMDB0001201 HMDB O7P2 Pyrophosphate 173.91193 Aspartate ammonia-lyase P0A786 UniProt ReactionCatalysis2635 ACTIVATION SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CNC2=O ReactionCatalysis2636 ACTIVATION 6082 ChemSpider ReactionCatalysis2639 ACTIVATION 5957 PubChem-compound ReactionCatalysis2638 ACTIVATION 562 TAXONOMY CHEBI:15996 ChEBI L-Asparagine L-Glutamine Argininosuccinate synthase Asparagine synthetase B [glutamine-hydrolyzing] 56-65-5 CAS C00020 KEGG Compound C00027 KEGG Compound L-Glutamic acid Aspartate carbamoyltransferase catalytic chain C00026 KEGG Compound C00025 KEGG Compound Guanosine triphosphate ReactionCatalysis2644 ACTIVATION ReactionCatalysis2643 ACTIVATION ReactionCatalysis2645 ACTIVATION Adenosine triphosphate Adenylosuccinate lyase SMILES N[C@@H](CC(O)=O)C(O)=O 16059 ChemSpider ReactionCatalysis2642 ACTIVATION ReactionCatalysis2641 ACTIVATION P0AB89 UniProt 1.0 SMP0000802 SMPDB SMILES N[C@@H](CCCNC(N)=O)C(O)=O SMP0000809 SMPDB CPD-8587 BioCyc C00152 KEGG Compound Adenylosuccinate synthetase 9367 ChemSpider C00036 KEGG Compound C00035 KEGG Compound CHEBI:15682 ChEBI HMDB0000134 HMDB Aspartate carbamoyltransferase regulatory chain 328-50-7 CAS Water AMP BioCyc Hydrogen peroxide Oxalacetic acid SubPathwayInput HYDROGEN-PEROXIDE BioCyc IMP BioCyc HMDB0000250 HMDB SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS asparagine synthetase P0A7D4 UniProt CHEBI:17196 ChEBI C00044 KEGG Compound C00049 KEGG Compound C03794 KEGG Compound 56-85-9 CAS 763 ChemSpider 1.0 HMDB0000148 HMDB L-aspartate oxidase 1.0 1.0 1.0 2.0 784 PubChem-compound 10197150 ChemSpider CHEBI:15422 ChEBI 2.0 Reaction2649 false Adenosine triphosphate + Citrulline + L-Aspartic acid → Adenosine monophosphate + Argininosuccinic acid + Pyrophosphate LEFT_TO_RIGHT FUM BioCyc Escherichia coli SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS CHEBI:18012 ChEBI 61-19-8 CAS Aspartate ammonia-lyase SMILES N[C@@H](CCCNC(N)=N)C(O)=O SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 1.0 Argininosuccinate lyase O2 Oxygen 31.98983 Aspartate aminotransferase SMILES N[C@@H](CCCNC(=N)N[C@@H](CC(O)=O)C(O)=O)C(O)=O C00062 KEGG Compound AMMONIA BioCyc SMILES N 56-86-0 CAS 28782 PubChem-compound 6.3.4.4 false 6.3.4.4 Guanosine triphosphate + Inosinic acid + L-Aspartic acid → Adenylsuccinic acid + Guanosine diphosphate + Phosphate LEFT_TO_RIGHT 1.4.3.16 false 1.4.3.16 L-Aspartic acid + Oxygen + Water → Ammonia + Hydrogen peroxide + Oxalacetic acid LEFT_TO_RIGHT 4.3.1.1 false 4.3.1.1 L-Aspartic acid → Ammonia + Fumaric acid LEFT_TO_RIGHT 6.3.5.4 false 6.3.5.4 Adenosine triphosphate + L-Aspartic acid + L-Glutamine + Water → Adenosine monophosphate + L-Asparagine + L-Glutamic acid + Pyrophosphate LEFT_TO_RIGHT C5H9NO4 L-Glutamic acid 147.05316 6.3.1.1 false 6.3.1.1 Adenosine triphosphate + Ammonia + L-Aspartic acid → Adenosine monophosphate + L-Asparagine + Pyrophosphate LEFT_TO_RIGHT 33032 PubChem-compound P0A7F3 UniProt C10H16N5O13P3 Adenosine triphosphate 506.99576 C14H18N5O11P Adenylsuccinic acid 463.07404 1.0 CHEBI:17053 ChEBI 1.0 C00064 KEGG Compound 8977 PubChem-compound P10902 UniProt 7782-44-7 CAS 2387-71-5 CAS HMDB0001377 HMDB HMDB0000045 HMDB HMDB0000168 HMDB 1.0 962 PubChem-compound Guanosine diphosphate 2-KETOGLUTARATE BioCyc Asparagine synthetase B [glutamine-hydrolyzing] 4.0 8630 ChemSpider Phosphate 1.0 389122 ChemSpider SubPathwayInteraction83538 SubPathway83538Reaction SubPathwayReaction SMILES O=O 1.0 HMDB0000051 HMDB Reaction2667 false L-Glutamic acid + Oxalacetic acid → L-Aspartic acid + Oxoglutaric acid LEFT_TO_RIGHT C4H8N2O3 L-Asparagine 132.0535 HMDB0002111 HMDB SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0000052 HMDB CHEBI:15919 ChEBI HMDB0000175 HMDB CHEBI:15377 ChEBI CHEBI:15379 ChEBI 14265-44-2 CAS CHEBI:16467 ChEBI CHEBI:16349 ChEBI 6569 ChemSpider C10H13N4O8P Inosinic acid 348.0471 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CN=C2NC(CC(O)=O)C(O)=O CHEBI:17552 ChEBI GTP BioCyc 2.1.3.2 false 2.1.3.2 L-Aspartic acid → N-carbamoyl-L-aspartate LEFT_TO_RIGHT Adenylsuccinic acid 4.3.2.2 false 4.3.2.2 Adenylsuccinic acid → Adenosine monophosphate + Fumaric acid LEFT_TO_RIGHT 1.0 L-Aspartic acid CHEBI:30744 ChEBI C4H7NO4 L-Aspartic acid 133.0375 P00963 UniProt HMDB0001273 HMDB 4.3.2.1 false 4.3.2.1 Argininosuccinic acid → Fumaric acid + L-Arginine LEFT_TO_RIGHT 644102 PubChem-compound SubPathwayInteraction83554 SubPathway83554Reaction SubPathwayReaction 6083 PubChem-compound SubPathwayInteraction83551 SubPathwayReaction SubPathway83551Reaction L-aspartate oxidase SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 Inosinic acid SMILES N[C@@H](CCC(N)=O)C(O)=O L-Aspartic acid SubPathwayInput 440122 PubChem-compound CHEBI:18050 ChEBI 1.0 H2O Water 18.010565 H2O2 Hydrogen peroxide 34.005478 L-Asparagine HMDB0000191 HMDB 1.0 86-01-1 CAS 1061 PubChem-compound 977 PubChem-compound 74-79-3 CAS SMILES OC(=N)NC(CC([O-])=O)C([O-])=O 56-84-8 CAS HMDB0000517 HMDB 970 PubChem-compound Argininosuccinate lyase Adenylosuccinate lyase SMP0000915 SMPDB SMILES OC(=O)\C=C\C(O)=O HMDB0000641 HMDB 1.0 P00509 UniProt 70-47-3 CAS 146-91-8 CAS 1.0 2.0 Asparagine synthetase B [glutamine- hydrolyzing] L-aspartate oxidase Aspartate ammonia-lyase Adenylosuccinate synthetase Argininosuccinate synthase Argininosuccinate lyase Aspartate carbamoyltransferase regulatory chain Aspartate carbamoyltransferase catalytic chain Aspartate aminotransferase Aspartate-- ammonia ligase Adenylosuccinate lyase Oxalacetic acid L-Aspartic acid ATP L-Glutamine H 2 O AMP PP i L-Asparagine L-Glutamic acid H 2 O O 2 NH 3 H 2 O 2 Fumaric acid NH 3 GTP Inosinic acid GDP P i Adenylsuccinic acid ATP Citrulline PP i AMP Argininosuccinic acid Fumaric acid L-Arginine N-carbamoyl- L-aspartate L-Glutamic acid Oxoglutaric acid ATP NH 3 AMP PP i AMP TCA Cycle NAD Biosynthesis beta-Alanine Metabolism
CHEBI:16015 ChEBI 30572 ChemSpider 1.0 7722-84-1 CAS C4H4O5 Oxalacetic acid 132.00587 adenylosuccinate synthase 937 ChemSpider aspartate ammonia-lyase aspartate carbamoyltransferase argininosuccinate synthase 6267 PubChem-compound CHEBI:16134 ChEBI asparagine synthetase II HMDB0003125 HMDB Adenosine monophosphate 1.0 110-17-8 CAS 21883788 PubChem-compound HMDB0000536 HMDB SMILES O SMILES OO C10H18N4O6 Argininosuccinic acid 290.12262 H3N Ammonia 17.026548 C6H14N4O2 L-Arginine 174.11168 C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate 50 ChemSpider C00327 KEGG Compound CHEBI:16027 ChEBI P0AC38 UniProt 6992098 PubChem-compound C5H6N2O5 N-carbamoyl-L-aspartate 174.02876 HMDB0000538 HMDB 6.0 OXALACETIC_ACID BioCyc 1.0 ATP BioCyc 5961 PubChem-compound Citrulline 1.0 1.0 328-42-7 CAS 1.0 131-99-7 CAS 51 PubChem-compound 559142 ChemSpider 2.0 ReactionCatalysis2660 ACTIVATION 1.0 CHEBI:17202 ChEBI NAD Biosynthesis SubPathway 8582 PubChem-compound 5746 ChemSpider 5745 ChemSpider 5742 ChemSpider ASN BioCyc Argininosuccinate synthase Argininosuccinic acid 1.0 L-ASPARTATE BioCyc 952 ChemSpider Aspartate carbamoyltransferase catalytic chain GO:0005829 GENE ONTOLOGY Ammonia L-Arginine Adenosine monophosphate C5H6O5 Oxoglutaric acid 146.02153 5858 ChemSpider ARG BioCyc 1.0 Ammonia Aspartate aminotransferase L-CITRULLINE BioCyc Pyrophosphate O4P Phosphate 94.95342 Oxalacetic acid CHEBI:16240 ChEBI 945 ChemSpider 6830 PubChem-compound 16950 PubChem-compound C10H15N5O11P2 Guanosine diphosphate 443.02432 6031 ChemSpider 1.0 PW000829 PathWhiz PPI BioCyc Adenylosuccinate synthetase 21960964 PubChem-compound 1.0 P0A6E4 UniProt P11447 UniProt adenylosuccinate lyase 2 PW000787 PathWhiz C10H16N5O14P3 Guanosine triphosphate 522.99066 1.0 Fumaric acid C5H10N2O3 L-Glutamine 146.06914 Aspartate--ammonia ligase Adenylsuccinic acid HMDB0000208 HMDB Cytosol CPD-6641 BioCyc 1.0 217 ChemSpider SMP0000849 SMPDB Adenosine triphosphate P22106 UniProt L-Glutamic acid Aspartate carbamoyltransferase regulatory chain SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O Oxygen CHEBI:30915 ChEBI PW000779 PathWhiz C00009 KEGG Compound C00007 KEGG Compound beta-Alanine Metabolism SubPathway 1.0 PW000896 PathWhiz C00001 KEGG Compound C00122 KEGG Compound HMDB0001429 HMDB 19046-78-7 CAS CHEBI:18361 ChEBI SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 CHEBI:18367 ChEBI 1032 ChemSpider aspartate transaminase 1.0 C00002 KEGG Compound HMDB0000223 HMDB GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc Fumaric acid GLN BioCyc GLT BioCyc 7664-41-7 CAS C4H4O4 Fumaric acid 116.010956 6.0 Aspartate Metabolism 1.0 N-carbamoyl-L-aspartate Aspartate--ammonia ligase C6H13N3O3 Citrulline 175.09569 Oxoglutaric acid 372-75-8 CAS C03406 KEGG Compound 44367445 PubChem-compound 1.0 4.0 TCA Cycle SubPathway C00130 KEGG Compound 222 PubChem-compound HMDB0000904 HMDB C00014 KEGG Compound C00013 KEGG Compound 4.0 SMILES N[C@@H](CC(N)=O)C(O)=O 8264 ChemSpider HMDB0001201 HMDB O7P2 Pyrophosphate 173.91193 Aspartate ammonia-lyase P0A786 UniProt ReactionCatalysis2635 ACTIVATION SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CNC2=O ReactionCatalysis2636 ACTIVATION 6082 ChemSpider ReactionCatalysis2639 ACTIVATION 5957 PubChem-compound ReactionCatalysis2638 ACTIVATION 562 TAXONOMY CHEBI:15996 ChEBI L-Asparagine L-Glutamine Argininosuccinate synthase Asparagine synthetase B [glutamine-hydrolyzing] 56-65-5 CAS C00020 KEGG Compound C00027 KEGG Compound L-Glutamic acid Aspartate carbamoyltransferase catalytic chain C00026 KEGG Compound C00025 KEGG Compound Guanosine triphosphate ReactionCatalysis2644 ACTIVATION ReactionCatalysis2643 ACTIVATION ReactionCatalysis2645 ACTIVATION Adenosine triphosphate Adenylosuccinate lyase SMILES N[C@@H](CC(O)=O)C(O)=O 16059 ChemSpider ReactionCatalysis2642 ACTIVATION ReactionCatalysis2641 ACTIVATION P0AB89 UniProt 1.0 SMP0000802 SMPDB SMILES N[C@@H](CCCNC(N)=O)C(O)=O SMP0000809 SMPDB CPD-8587 BioCyc C00152 KEGG Compound Adenylosuccinate synthetase 9367 ChemSpider C00036 KEGG Compound C00035 KEGG Compound CHEBI:15682 ChEBI HMDB0000134 HMDB Aspartate carbamoyltransferase regulatory chain 328-50-7 CAS Water AMP BioCyc Hydrogen peroxide Oxalacetic acid SubPathwayInput HYDROGEN-PEROXIDE BioCyc IMP BioCyc HMDB0000250 HMDB SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS asparagine synthetase P0A7D4 UniProt CHEBI:17196 ChEBI C00044 KEGG Compound C00049 KEGG Compound C03794 KEGG Compound 56-85-9 CAS 763 ChemSpider 1.0 HMDB0000148 HMDB L-aspartate oxidase 1.0 1.0 1.0 2.0 784 PubChem-compound 10197150 ChemSpider CHEBI:15422 ChEBI 2.0 Reaction2649 false Adenosine triphosphate + Citrulline + L-Aspartic acid → Adenosine monophosphate + Argininosuccinic acid + Pyrophosphate LEFT_TO_RIGHT FUM BioCyc Escherichia coli SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS CHEBI:18012 ChEBI 61-19-8 CAS Aspartate ammonia-lyase SMILES N[C@@H](CCCNC(N)=N)C(O)=O SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 1.0 Argininosuccinate lyase O2 Oxygen 31.98983 Aspartate aminotransferase SMILES N[C@@H](CCCNC(=N)N[C@@H](CC(O)=O)C(O)=O)C(O)=O C00062 KEGG Compound AMMONIA BioCyc SMILES N 56-86-0 CAS 28782 PubChem-compound 6.3.4.4 false 6.3.4.4 Guanosine triphosphate + Inosinic acid + L-Aspartic acid → Adenylsuccinic acid + Guanosine diphosphate + Phosphate LEFT_TO_RIGHT 1.4.3.16 false 1.4.3.16 L-Aspartic acid + Oxygen + Water → Ammonia + Hydrogen peroxide + Oxalacetic acid LEFT_TO_RIGHT 4.3.1.1 false 4.3.1.1 L-Aspartic acid → Ammonia + Fumaric acid LEFT_TO_RIGHT 6.3.5.4 false 6.3.5.4 Adenosine triphosphate + L-Aspartic acid + L-Glutamine + Water → Adenosine monophosphate + L-Asparagine + L-Glutamic acid + Pyrophosphate LEFT_TO_RIGHT C5H9NO4 L-Glutamic acid 147.05316 6.3.1.1 false 6.3.1.1 Adenosine triphosphate + Ammonia + L-Aspartic acid → Adenosine monophosphate + L-Asparagine + Pyrophosphate LEFT_TO_RIGHT 33032 PubChem-compound P0A7F3 UniProt C10H16N5O13P3 Adenosine triphosphate 506.99576 C14H18N5O11P Adenylsuccinic acid 463.07404 1.0 CHEBI:17053 ChEBI 1.0 C00064 KEGG Compound 8977 PubChem-compound P10902 UniProt 7782-44-7 CAS 2387-71-5 CAS HMDB0001377 HMDB HMDB0000045 HMDB HMDB0000168 HMDB 1.0 962 PubChem-compound Guanosine diphosphate 2-KETOGLUTARATE BioCyc Asparagine synthetase B [glutamine-hydrolyzing] 4.0 8630 ChemSpider Phosphate 1.0 389122 ChemSpider SubPathwayInteraction83538 SubPathway83538Reaction SubPathwayReaction SMILES O=O 1.0 HMDB0000051 HMDB Reaction2667 false L-Glutamic acid + Oxalacetic acid → L-Aspartic acid + Oxoglutaric acid LEFT_TO_RIGHT C4H8N2O3 L-Asparagine 132.0535 HMDB0002111 HMDB SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0000052 HMDB CHEBI:15919 ChEBI HMDB0000175 HMDB CHEBI:15377 ChEBI CHEBI:15379 ChEBI 14265-44-2 CAS CHEBI:16467 ChEBI CHEBI:16349 ChEBI 6569 ChemSpider C10H13N4O8P Inosinic acid 348.0471 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CN=C2NC(CC(O)=O)C(O)=O CHEBI:17552 ChEBI GTP BioCyc 2.1.3.2 false 2.1.3.2 L-Aspartic acid → N-carbamoyl-L-aspartate LEFT_TO_RIGHT Adenylsuccinic acid 4.3.2.2 false 4.3.2.2 Adenylsuccinic acid → Adenosine monophosphate + Fumaric acid LEFT_TO_RIGHT 1.0 L-Aspartic acid CHEBI:30744 ChEBI C4H7NO4 L-Aspartic acid 133.0375 P00963 UniProt HMDB0001273 HMDB 4.3.2.1 false 4.3.2.1 Argininosuccinic acid → Fumaric acid + L-Arginine LEFT_TO_RIGHT 644102 PubChem-compound SubPathwayInteraction83554 SubPathway83554Reaction SubPathwayReaction 6083 PubChem-compound SubPathwayInteraction83551 SubPathwayReaction SubPathway83551Reaction L-aspartate oxidase SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 Inosinic acid SMILES N[C@@H](CCC(N)=O)C(O)=O L-Aspartic acid SubPathwayInput 440122 PubChem-compound CHEBI:18050 ChEBI 1.0 H2O Water 18.010565 H2O2 Hydrogen peroxide 34.005478 L-Asparagine HMDB0000191 HMDB 1.0 86-01-1 CAS 1061 PubChem-compound 977 PubChem-compound 74-79-3 CAS SMILES OC(=N)NC(CC([O-])=O)C([O-])=O 56-84-8 CAS HMDB0000517 HMDB 970 PubChem-compound Argininosuccinate lyase Adenylosuccinate lyase SMP0000915 SMPDB SMILES OC(=O)\C=C\C(O)=O HMDB0000641 HMDB 1.0 P00509 UniProt 70-47-3 CAS 146-91-8 CAS 1.0 2.0 asnB nadB aspA purA argG argH pyrI pyrB aspC asnA purB Oxalacetic acid L-Aspartic acid Adenosine triphosphate L-Glutamine Water Adenosine monophosphate Pyrophosphate L-Asparagine L-Glutamic acid Water Oxygen Ammonia Hydrogen peroxide Fumaric acid Ammonia Guanosine triphosphate Inosinic acid Guanosine diphosphate Phosphate Adenylsuccinic acid Adenosine triphosphate Citrulline Pyrophosphate Adenosine monophosphate Argininosuccinic acid Fumaric acid L-Arginine N-carbamoyl- L-aspartate L-Glutamic acid Oxoglutaric acid Adenosine triphosphate Ammonia Adenosine monophosphate Pyrophosphate Adenosine monophosphate TCA Cycle NAD Biosynthesis beta-Alanine Metabolism