Loading Pathway...
CHEBI:16015 ChEBI C5H11NO2 L-Valine 117.07898 2.0 30572 ChemSpider 6022 PubChem-compound SMILES N[C@@H](CS)C(O)=O 937 ChemSpider CYS BioCyc 1.0 ReactionCatalysis2655 ACTIVATION ReactionCatalysis2654 ACTIVATION ReactionCatalysis2657 ACTIVATION ReactionCatalysis2656 ACTIVATION Uncharacterized aminotransferase yfbQ SMILES O 50 ChemSpider ReactionCatalysis2653 ACTIVATION HMDB0003364 HMDB P0A6J8 UniProt Branched-chain-amino-acid aminotransferase HMDB0000538 HMDB glutamate-pyruvate aminotransferase ATP BioCyc SubPathwayInteraction83622 SubPathway83622Reaction SubPathwayReaction C3H7NO2 D-Alanine 89.047676 SubPathwayInteraction83627 SubPathwayReaction SubPathway83627Reaction CHEBI:17594 ChEBI P09053 UniProt H4N Ammonium 18.034374 cysteine desulfurase 1.0 1.0 64234 ChemSpider 48 ChemSpider 51 PubChem-compound Pyruvic acid ADP BioCyc C3H4O3 Pyruvic acid 88.016045 P0A6J5 UniProt 2.0 6287 PubChem-compound D-alanine--D-alanine ligase B 1.0 D-Alanine SubPathwayInput an [L-cysteine desulfurase] L-cysteine persulfide D-Alanine 5742 ChemSpider CHEBI:17561 ChEBI SubPathwayInteraction83636 SubPathwayReaction SubPathway83636Reaction GO:0005829 GENE ONTOLOGY 759-05-7 CAS Alanine racemase, biosynthetic D-amino acid dehydrogenase Valine Transaminase C5H6O5 Oxoglutaric acid 146.02153 C5H8O3 alpha-Ketoisovaleric acid 116.04734 L-Valine 2.0 5735 ChemSpider SubPathwayInteraction83640 SubPathway83640Reaction SubPathwayReaction O4P Phosphate 94.95342 D-alanine--D-alanine ligase A C6H12N2O3 D-Alanyl-D-alanine 160.0848 5862 PubChem-compound 4650 PubChem-compound Alanine racemase, catabolic 1.0 D-amino acid dehydrogenase small subunit 2-KETO-ISOVALERATE BioCyc 1.0 Valine--pyruvate aminotransferase Ammonium PW000785 PathWhiz P07862 UniProt CHEBI:16977 ChEBI HMDB0000208 HMDB 236-TRICHLOROHYDROQUINONE BioCyc C00472 KEGG Compound Cytosol 218 ChemSpider Adenosine triphosphate HMDB0000574 HMDB L-Glutamic acid Quinone SMILES [O-]P([O-])([O-])=O ReactionCatalysis3706 ACTIVATION SMILES OC(=O)CCC(=O)C(O)=O SMILES CC(C)C(=O)C(O)=O CHEBI:30915 ChEBI D-ALANINE BioCyc C00009 KEGG Compound C00008 KEGG Compound 2.0 SMILES C[C@@H](N)C(=O)N[C@H](C)C(O)=O HMDB0001429 HMDB L-ALPHA-ALANINE BioCyc C00001 KEGG Compound Uncharacterized aminotransferase yfbQ 56-41-7 CAS 1.0 CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound 1031 ChemSpider HMDB0001310 HMDB 6050 ChemSpider GLT BioCyc 49 PubChem-compound Glycolysis and Pyruvate Dehydrogenase SubPathway Alanine racemase, biosynthetic Pyruvic acid SubPathwayInput Cysteine desulfurase Peptidoglycan Biosynthesis I SubPathway C00133 KEGG Compound C01342 KEGG Compound SMILES C[C@H](N)C(O)=O CHEBI:28938 ChEBI 5950 PubChem-compound 5957 PubChem-compound L-Glutamate Metabolism SubPathway L-Alanine Metabolism 562 TAXONOMY C00022 KEGG Compound 56-65-5 CAS C00141 KEGG Compound 5653 ChemSpider L-Glutamic acid SubPathwayInput 338-69-2 CAS C00026 KEGG Compound C00025 KEGG Compound 4573916 ChemSpider Adenosine diphosphate HMDB0000243 HMDB 1.0 D-alanine ligase C10H15N5O10P2 Adenosine diphosphate 427.02942 1.0 Cysteine Biosynthesis SubPathway SMP0000924 SMPDB CHEBI:16414 ChEBI D-amino acid dehydrogenase small subunit C6H6O2 Hydroquinone 110.03678 D-alanine--D-alanine ligase A 52-90-4 CAS CPD-8587 BioCyc SMP0000807 SMPDB CHEBI:16530 ChEBI 328-50-7 CAS HMDB0002434 HMDB Water C00041 KEGG Compound Uncharacterized aminotransferase yfdZ HMDB0000019 HMDB P0AB80 UniProt 1.0 1.0 5460362 PubChem-compound HMDB0001341 HMDB Cysteine desulfurase SMP0000810 SMPDB P0A6B4 UniProt SMP0000811 SMPDB P0A6B7 UniProt CHEBI:15570 ChEBI SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 764 ChemSpider HMDB0000148 HMDB 14798-03-9 CAS 1.0 1.0 CHEBI:15422 ChEBI 785 PubChem-compound SMP0000821 SMPDB Escherichia coli 1.0 7732-18-5 CAS SMILES CC(C)[C@H](N)C(O)=O 72-18-4 CAS 127-17-3 CAS C00183 KEGG Compound C6H4O2 Quinone 108.021126 56-86-0 CAS CHEBI:16509 ChEBI 6.0 Reaction3732 false L-Alanine → D-Alanine LEFT_TO_RIGHT C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound SMILES [NH4+] C10H16N5O13P3 Adenosine triphosphate 506.99576 4489 ChemSpider SMILES C[C@@H](N)C(O)=O 1.0 CPD-8130 BioCyc Hydroquinone CHEBI:16761 ChEBI Alanine racemase, catabolic SMILES CC(=O)C(O)=O 71080 PubChem-compound 123-31-9 CAS 6.3.2.4 false 6.3.2.4 Adenosine triphosphate + 2 D-Alanine → Adenosine diphosphate + D-Alanyl-D-alanine + Phosphate LEFT_TO_RIGHT HMDB0000161 HMDB PW000789 PathWhiz PW000788 PathWhiz 923-16-0 CAS CHEBI:16576 ChEBI 962 PubChem-compound P29012 UniProt L-alanine racemase C3H7NO2 L-Alanine 89.047676 2-KETOGLUTARATE BioCyc 5800 ChemSpider L-Alanine SubPathwayInteraction83651 SubPathway83651Reaction SubPathwayReaction D-Alanyl-D-alanine Branched-chain-amino-acid aminotransferase Phosphate C00993 KEGG Compound 1.0 2.8.1.7 false 2.8.1.7 L-Cysteine + an [L-cysteine desulfurase] L-cysteine persulfide → L-Alanine + an [L-cysteine desulfurase] L-cysteine persulfide LEFT_TO_RIGHT 2.6.1.66 false 2.6.1.66 L-Valine + Pyruvic acid → L-Alanine + alpha-Ketoisovaleric acid LEFT_TO_RIGHT 2.6.1.2 false 2.6.1.2 L-Glutamic acid + Pyruvic acid → L-Alanine + Oxoglutaric acid LEFT_TO_RIGHT Oxoglutaric acid 1.0 alpha-Ketoisovaleric acid SMILES O=C1C=CC(=O)C=C1 CHEBI:32816 ChEBI SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0002111 HMDB 2.6.1.42 false 2.6.1.42 L-Glutamic acid + alpha-Ketoisovaleric acid → L-Valine + Oxoglutaric acid LEFT_TO_RIGHT 1.4.99.1 false 1.4.99.1 D-Alanine + Quinone + Water → Ammonium + Hydroquinone + Pyruvic acid LEFT_TO_RIGHT CHEBI:15377 ChEBI L-Cysteine SubPathwayOutput D-Alanyl-D-alanine SubPathwayInput 14265-44-2 CAS PYRUVATE BioCyc 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Uncharacterized aminotransferase yfdZ D-alanine--D-alanine ligase B VAL BioCyc 1.0 1.0 SMILES OC1=CC=C(O)C=C1 HMDB0003459 HMDB PW000800 PathWhiz C3H7NO2S L-Cysteine 121.01975 16741146 PubChem-compound C00097 KEGG Compound C00530 KEGG Compound H2O Water 18.010565 P77434 UniProt 1060 PubChem-compound 1061 PubChem-compound HMDB0041827 HMDB ReactionCatalysis2480 ACTIVATION L-Alanine 106-51-4 CAS 2.0 D-ALA-D-ALA BioCyc Valine--pyruvate aminotransferase HMDB0000883 HMDB PW000906 PathWhiz P0A959 UniProt an [L-cysteine desulfurase] L-cysteine persulfide D-alanine--D- alanine ligase B D-alanine--D- alanine ligase A Uncharacterized aminotransferase yfdZ Uncharacterized aminotransferase yfbQ Valine-- pyruvate aminotransferase Branched- chain-amino- acid aminotransferase D-amino acid dehydrogenase small subunit Cysteine desulfurase Alanine racemase, catabolic Alanine racemase, biosynthetic D-Alanine D-Alanyl-D- alanine Pyruvic acid L-Cysteine Pyruvic acid L-Glutamic acid ATP ADP P i L-Glutamic acid Oxoglutaric acid L-Alanine L-Valine Pyruvic acid alpha- Ketoisovaleric acid alpha- Ketoisovaleric acid Oxoglutaric acid H 2 O Quinone Ammonium Hydroquinone an [L-cysteine desulfurase] L-cysteine persulfide an [L-cysteine desulfurase] L-cysteine persulfide Peptidoglycan Biosynthesis I Glycolysis and Pyruvate Dehydrogenase Cysteine Biosynthesis Glycolysis and Pyruvate Dehydrogenase L-Glutamate Metabolism
CHEBI:16015 ChEBI C5H11NO2 L-Valine 117.07898 2.0 30572 ChemSpider 6022 PubChem-compound SMILES N[C@@H](CS)C(O)=O 937 ChemSpider CYS BioCyc 1.0 ReactionCatalysis2655 ACTIVATION ReactionCatalysis2654 ACTIVATION ReactionCatalysis2657 ACTIVATION ReactionCatalysis2656 ACTIVATION Uncharacterized aminotransferase yfbQ SMILES O 50 ChemSpider ReactionCatalysis2653 ACTIVATION HMDB0003364 HMDB P0A6J8 UniProt Branched-chain-amino-acid aminotransferase HMDB0000538 HMDB glutamate-pyruvate aminotransferase ATP BioCyc SubPathwayInteraction83622 SubPathway83622Reaction SubPathwayReaction C3H7NO2 D-Alanine 89.047676 SubPathwayInteraction83627 SubPathwayReaction SubPathway83627Reaction CHEBI:17594 ChEBI P09053 UniProt H4N Ammonium 18.034374 cysteine desulfurase 1.0 1.0 64234 ChemSpider 48 ChemSpider 51 PubChem-compound Pyruvic acid ADP BioCyc C3H4O3 Pyruvic acid 88.016045 P0A6J5 UniProt 2.0 6287 PubChem-compound D-alanine--D-alanine ligase B 1.0 D-Alanine SubPathwayInput an [L-cysteine desulfurase] L-cysteine persulfide D-Alanine 5742 ChemSpider CHEBI:17561 ChEBI SubPathwayInteraction83636 SubPathwayReaction SubPathway83636Reaction GO:0005829 GENE ONTOLOGY 759-05-7 CAS Alanine racemase, biosynthetic D-amino acid dehydrogenase Valine Transaminase C5H6O5 Oxoglutaric acid 146.02153 C5H8O3 alpha-Ketoisovaleric acid 116.04734 L-Valine 2.0 5735 ChemSpider SubPathwayInteraction83640 SubPathway83640Reaction SubPathwayReaction O4P Phosphate 94.95342 D-alanine--D-alanine ligase A C6H12N2O3 D-Alanyl-D-alanine 160.0848 5862 PubChem-compound 4650 PubChem-compound Alanine racemase, catabolic 1.0 D-amino acid dehydrogenase small subunit 2-KETO-ISOVALERATE BioCyc 1.0 Valine--pyruvate aminotransferase Ammonium PW000785 PathWhiz P07862 UniProt CHEBI:16977 ChEBI HMDB0000208 HMDB 236-TRICHLOROHYDROQUINONE BioCyc C00472 KEGG Compound Cytosol 218 ChemSpider Adenosine triphosphate HMDB0000574 HMDB L-Glutamic acid Quinone SMILES [O-]P([O-])([O-])=O ReactionCatalysis3706 ACTIVATION SMILES OC(=O)CCC(=O)C(O)=O SMILES CC(C)C(=O)C(O)=O CHEBI:30915 ChEBI D-ALANINE BioCyc C00009 KEGG Compound C00008 KEGG Compound 2.0 SMILES C[C@@H](N)C(=O)N[C@H](C)C(O)=O HMDB0001429 HMDB L-ALPHA-ALANINE BioCyc C00001 KEGG Compound Uncharacterized aminotransferase yfbQ 56-41-7 CAS 1.0 CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound 1031 ChemSpider HMDB0001310 HMDB 6050 ChemSpider GLT BioCyc 49 PubChem-compound Glycolysis and Pyruvate Dehydrogenase SubPathway Alanine racemase, biosynthetic Pyruvic acid SubPathwayInput Cysteine desulfurase Peptidoglycan Biosynthesis I SubPathway C00133 KEGG Compound C01342 KEGG Compound SMILES C[C@H](N)C(O)=O CHEBI:28938 ChEBI 5950 PubChem-compound 5957 PubChem-compound L-Glutamate Metabolism SubPathway L-Alanine Metabolism 562 TAXONOMY C00022 KEGG Compound 56-65-5 CAS C00141 KEGG Compound 5653 ChemSpider L-Glutamic acid SubPathwayInput 338-69-2 CAS C00026 KEGG Compound C00025 KEGG Compound 4573916 ChemSpider Adenosine diphosphate HMDB0000243 HMDB 1.0 D-alanine ligase C10H15N5O10P2 Adenosine diphosphate 427.02942 1.0 Cysteine Biosynthesis SubPathway SMP0000924 SMPDB CHEBI:16414 ChEBI D-amino acid dehydrogenase small subunit C6H6O2 Hydroquinone 110.03678 D-alanine--D-alanine ligase A 52-90-4 CAS CPD-8587 BioCyc SMP0000807 SMPDB CHEBI:16530 ChEBI 328-50-7 CAS HMDB0002434 HMDB Water C00041 KEGG Compound Uncharacterized aminotransferase yfdZ HMDB0000019 HMDB P0AB80 UniProt 1.0 1.0 5460362 PubChem-compound HMDB0001341 HMDB Cysteine desulfurase SMP0000810 SMPDB P0A6B4 UniProt SMP0000811 SMPDB P0A6B7 UniProt CHEBI:15570 ChEBI SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 764 ChemSpider HMDB0000148 HMDB 14798-03-9 CAS 1.0 1.0 CHEBI:15422 ChEBI 785 PubChem-compound SMP0000821 SMPDB Escherichia coli 1.0 7732-18-5 CAS SMILES CC(C)[C@H](N)C(O)=O 72-18-4 CAS 127-17-3 CAS C00183 KEGG Compound C6H4O2 Quinone 108.021126 56-86-0 CAS CHEBI:16509 ChEBI 6.0 Reaction3732 false L-Alanine → D-Alanine LEFT_TO_RIGHT C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound SMILES [NH4+] C10H16N5O13P3 Adenosine triphosphate 506.99576 4489 ChemSpider SMILES C[C@@H](N)C(O)=O 1.0 CPD-8130 BioCyc Hydroquinone CHEBI:16761 ChEBI Alanine racemase, catabolic SMILES CC(=O)C(O)=O 71080 PubChem-compound 123-31-9 CAS 6.3.2.4 false 6.3.2.4 Adenosine triphosphate + 2 D-Alanine → Adenosine diphosphate + D-Alanyl-D-alanine + Phosphate LEFT_TO_RIGHT HMDB0000161 HMDB PW000789 PathWhiz PW000788 PathWhiz 923-16-0 CAS CHEBI:16576 ChEBI 962 PubChem-compound P29012 UniProt L-alanine racemase C3H7NO2 L-Alanine 89.047676 2-KETOGLUTARATE BioCyc 5800 ChemSpider L-Alanine SubPathwayInteraction83651 SubPathway83651Reaction SubPathwayReaction D-Alanyl-D-alanine Branched-chain-amino-acid aminotransferase Phosphate C00993 KEGG Compound 1.0 2.8.1.7 false 2.8.1.7 L-Cysteine + an [L-cysteine desulfurase] L-cysteine persulfide → L-Alanine + an [L-cysteine desulfurase] L-cysteine persulfide LEFT_TO_RIGHT 2.6.1.66 false 2.6.1.66 L-Valine + Pyruvic acid → L-Alanine + alpha-Ketoisovaleric acid LEFT_TO_RIGHT 2.6.1.2 false 2.6.1.2 L-Glutamic acid + Pyruvic acid → L-Alanine + Oxoglutaric acid LEFT_TO_RIGHT Oxoglutaric acid 1.0 alpha-Ketoisovaleric acid SMILES O=C1C=CC(=O)C=C1 CHEBI:32816 ChEBI SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0002111 HMDB 2.6.1.42 false 2.6.1.42 L-Glutamic acid + alpha-Ketoisovaleric acid → L-Valine + Oxoglutaric acid LEFT_TO_RIGHT 1.4.99.1 false 1.4.99.1 D-Alanine + Quinone + Water → Ammonium + Hydroquinone + Pyruvic acid LEFT_TO_RIGHT CHEBI:15377 ChEBI L-Cysteine SubPathwayOutput D-Alanyl-D-alanine SubPathwayInput 14265-44-2 CAS PYRUVATE BioCyc 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Uncharacterized aminotransferase yfdZ D-alanine--D-alanine ligase B VAL BioCyc 1.0 1.0 SMILES OC1=CC=C(O)C=C1 HMDB0003459 HMDB PW000800 PathWhiz C3H7NO2S L-Cysteine 121.01975 16741146 PubChem-compound C00097 KEGG Compound C00530 KEGG Compound H2O Water 18.010565 P77434 UniProt 1060 PubChem-compound 1061 PubChem-compound HMDB0041827 HMDB ReactionCatalysis2480 ACTIVATION L-Alanine 106-51-4 CAS 2.0 D-ALA-D-ALA BioCyc Valine--pyruvate aminotransferase HMDB0000883 HMDB PW000906 PathWhiz P0A959 UniProt an [L-cysteine desulfurase] L-cysteine persulfide ddlB ddlA yfdZ yfbQ avtA ilvE dadA iscS dadX alr D-Alanine D-Alanyl-D- alanine Pyruvic acid L-Cysteine Pyruvic acid L-Glutamic acid Adenosine triphosphate Adenosine diphosphate Phosphate L-Glutamic acid Oxoglutaric acid L-Alanine L-Valine Pyruvic acid alpha- Ketoisovaleric acid alpha- Ketoisovaleric acid Oxoglutaric acid Water Quinone Ammonium Hydroquinone an [L-cysteine desulfurase] L-cysteine persulfide an [L-cysteine desulfurase] L-cysteine persulfide Peptidoglycan Biosynthesis I Glycolysis and Pyruvate Dehydrogenase Cysteine Biosynthesis Glycolysis and Pyruvate Dehydrogenase L-Glutamate Metabolism