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CHEBI:16015 ChEBI HMDB00254 HMDB Glutamate/aspartate transport system permease protein gltK HMDB00134 HMDB 6022 PubChem-compound 923 PubChem-compound 937 ChemSpider CHEBI:16134 ChEBI HMDB01341 HMDB P69910 UniProt 110-17-8 CAS 50 ChemSpider 1.0 Glutamate decarboxylase alpha 1.0 HMDB00148 HMDB P0AC38 UniProt OXALACETIC_ACID BioCyc Glutamate synthase [NADPH] small chain ATP BioCyc Glutamate/aspartate periplasmic-binding protein H4N Ammonium 18.034374 1.0 Glutamate synthase [NADPH] large chain P69908 UniProt Transport369 false L-Glutamic acid (→), Sodium (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 1.0 5746 ChemSpider 1.0 5745 ChemSpider Transport371 false Hydrogen Ion (→), L-Glutamic acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 5742 ChemSpider L-ASPARTATE BioCyc Glutamate/aspartate transport system permease protein gltJ CHEBI:16474 ChEBI Glutamate decarboxylase beta HMDB59597 HMDB Aerobic C4-dicarboxylate transport protein 945 ChemSpider Proton glutamate symport protein Glutamine synthetase 1010 ChemSpider 2.0 HMDB41827 HMDB Glutamate/aspartate transport ATP-binding protein gltL 23724570 PubChem-compound BiologicalState109 1.0 5105-96-4 CAS Ammonium ReactionCoupledTransportCatalysis136 ACTIVATION C5H10N2O3 L-Glutamine 146.06914 Hydrogen Ion SubPathwayInteraction1527 SubPathway1527Reaction SubPathwayReaction HMDB00217 HMDB SubPathwayInteraction1526 SubPathwayReaction SubPathway1526Reaction Cytosol Adenosine triphosphate SUC BioCyc Glutamine transport ATP-binding protein glnQ CHEBI:49260 ChEBI HMDB00208 HMDB C00009 KEGG Compound HMDB00221 HMDB C00008 KEGG Compound HMDB00223 HMDB C00006 KEGG Compound HMDB00588 HMDB 1.0 CHEBI:18009 ChEBI P0ABN5 UniProt Hydrogen Ion C00001 KEGG Compound C00122 KEGG Compound C01330 KEGG Compound ReactionCoupledTransportCatalysis141 ACTIVATION P0A6W0 UniProt C00005 KEGG Compound Glutamate/aspartate transport ATP-binding protein gltL CPD-9000 BioCyc CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound ReactionCoupledTransport107 false Adenosine triphosphate + L-Glutamine + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamine + Phosphate LEFT_TO_RIGHT Anaerobic C4-dicarboxylate transporter dcuC Anaerobic C4-dicarboxylate transporter dcuB HMDB01429 HMDB ReactionCoupledTransport102 false Adenosine triphosphate + L-Glutamic acid + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamic acid + Phosphate LEFT_TO_RIGHT 44367445 PubChem-compound C01342 KEGG Compound C00011 KEGG Compound glutaminase 1 C00014 KEGG Compound NAD(P) BioCyc glutaminase 2 562 TAXONOMY P0ABP1 UniProt H Hydrogen Ion 1.007825 P09832 UniProt P0ABP4 UniProt P09831 UniProt L-Glutamine 56-65-5 CAS Glutamate/aspartate periplasmic-binding protein L-Glutamic acid 1.0 C00026 KEGG Compound C00025 KEGG Compound ReactionCatalysis5119 ACTIVATION 1.0 CHEBI:29101 ChEBI Glutamine transport system permease protein glnP P0AAG3 UniProt C00036 KEGG Compound 899 ChemSpider 328-50-7 CAS Water SMILES OC(=O)CCC(O)=O 2.0 C15767 KEGG Compound P0AFR2 UniProt C00042 KEGG Compound C00049 KEGG Compound 56-85-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Anaerobic C4-dicarboxylate transporter dcuA HMDB00538 HMDB 17341-25-2 CAS 10197150 ChemSpider P0AEQ3 UniProt P0AEQ6 UniProt FUM BioCyc SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS CHEBI:18012 ChEBI Aspartate ammonia-lyase Glutamine transport system permease protein glnP AMMONIA BioCyc SMILES N 56-86-0 CAS HMDB00641 HMDB P0AER3 UniProt C10H16N5O13P3 Adenosine triphosphate 506.99576 P0AER5 UniProt CHEBI:17053 ChEBI 1.0 P0AER8 UniProt C00064 KEGG Compound Sodium/glutamate symport carrier protein Glutamate/aspartate transport system permease protein gltK L-Glutamic acid Glutamate/aspartate transport system permease protein gltJ HMDB01967 HMDB 962 PubChem-compound 5800 ChemSpider glutamine ABC transporter 4.0 Sodium CO2 Carbon dioxide 43.98983 SMILES N[C@@H](CCC(=O)NCCCC(O)=O)C(O)=O Phosphate C00080 KEGG Compound Periplasmic Space Oxoglutaric acid TransportCatalysis317 ACTIVATION TransportCatalysis315 ACTIVATION SMILES N[C@@H](CCC(O)=O)C(O)=O 14265-44-2 CAS 58-64-0 CAS Putative sulfate transporter ychM Glutamine transport ATP-binding protein glnQ L-Aspartic acid 1.0 Transport448 false Fumaric acid (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C4H7NO4 L-Aspartic acid 133.0375 Transport447 false Fumaric acid (→), Succinic acid (←) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport446 false Fumaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Fumaric acid Glutamine synthetase 22833512 PubChem-compound CHEBI:18050 ChEBI H2O Water 18.010565 Proton glutamate symport protein Aerobic C4-dicarboxylate transport protein Na Sodium 22.989769 L-Glutamic acid Carbon dioxide 56-84-8 CAS 21865667 ChemSpider 970 PubChem-compound SMILES OC(=O)\C=C\C(O)=O P0A830 UniProt 1.0 Adenosine diphosphate Reaction5146 false Hydrogen Ion + L-Glutamic acid → 4-(Glutamylamino) butanoate + Carbon dioxide LEFT_TO_RIGHT 1.0 30572 ChemSpider 17215925 ChemSpider C4H4O5 Oxalacetic acid 132.00587 L-Glutamine aspartate ammonia-lyase aspartate transaminase dicarboxylate transporter ReactionCatalysis2659 ACTIVATION ReactionCatalysis2658 ACTIVATION 21883788 PubChem-compound SMILES O H3N Ammonia 17.026548 SMILES [Na+] 5961 PubChem-compound SMP00959 SMPDB 1.0 1.0 328-42-7 CAS 51 PubChem-compound ReactionCatalysis2660 ACTIVATION Succinic acid ADP BioCyc ReactionCatalysis2662 ACTIVATION ReactionCatalysis2661 ACTIVATION P00370 UniProt 53-59-8 CAS 1038 PubChem-compound glutamate / aspartate ABC transporter glutamate decarboxylase 2.0 GO:0005829 GENE ONTOLOGY Ammonia 274 ChemSpider C5H6O5 Oxoglutaric acid 146.02153 NADP-specific glutamate dehydrogenase 1.0 Aspartate aminotransferase O4P Phosphate 94.95342 Oxalacetic acid NADPH GO:0070258 GENE ONTOLOGY NADP C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 PW000942 PathWhiz NADPH BioCyc Fumaric acid 218 ChemSpider 217 ChemSpider L-Glutamic acid SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O CHEBI:30915 ChEBI 124-38-9 CAS PW000779 PathWhiz Hydrogen Ion 4-(Glutamylamino) butanoate Inner Membrane SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O Fumaric acid 1.0 GLN BioCyc GLT BioCyc 7664-41-7 CAS C4H4O4 Fumaric acid 116.010956 Anaerobic C4-dicarboxylate transporter dcuA 53-57-6 CAS TransportCatalysis385 ACTIVATION Glutamate decarboxylase alpha 1.0 TransportCatalysis384 ACTIVATION SMP00802 SMPDB TransportCatalysis383 ACTIVATION CHEBI:15741 ChEBI 1.0 1.0 Glutamate synthase [NADPH] large chain Glutamate synthase [NADPH] small chain SMILES O=C=O CHEBI:28938 ChEBI 222 PubChem-compound 1110 PubChem-compound Sodium/glutamate symport carrier protein Aspartate ammonia-lyase 5957 PubChem-compound L-glutamate metabolism GO:0005620 GENE ONTOLOGY C4H6O4 Succinic acid 118.02661 1.0 SMP00810 SMPDB SMP00811 SMPDB Glutamate decarboxylase beta Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 SMILES N[C@@H](CC(O)=O)C(O)=O glutaminase Glutamine-binding periplasmic protein Adenosine triphosphate CPD-8587 BioCyc Putative sulfate transporter ychM Phosphate P37902 UniProt 1.0 5675 ChemSpider 1078 ChemSpider pyrimidine metabolism SubPathway 14798-03-9 CAS Water CHEBI:15422 ChEBI SubPathwayInteraction1505 SubPathway1505Reaction SubPathwayReaction HMDB00191 HMDB C9H16N2O5 4-(Glutamylamino) butanoate 232.10593 Anaerobic C4-dicarboxylate transporter dcuC Anaerobic C4-dicarboxylate transporter dcuB 1.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound SMILES [NH4+] P10346 UniProt 1.0 CHEBI:16526 ChEBI glutaminase 1 glutaminase 2 1.0 CHEBI:16761 ChEBI TCA cycle SubPathway L-alanine metabolism SubPathway P21345 UniProt Succinic acid PW000789 PathWhiz 3.5.1.2 false 3.5.1.2 L-Glutamine + Water → Ammonia + L-Glutamic acid LEFT_TO_RIGHT PW000788 PathWhiz 2-KETOGLUTARATE BioCyc P0A9C5 UniProt HMDB00051 HMDB 1.0 1.0 HMDB02111 HMDB 110-15-6 CAS HMDB12161 HMDB 1.0 Reaction2669 false Hydrogen Ion + L-Glutamine + NADPH + Oxoglutaric acid → 2 L-Glutamic acid + NADP LEFT_TO_RIGHT Reaction2667 false L-Glutamic acid + Oxalacetic acid → L-Aspartic acid + Oxoglutaric acid LEFT_TO_RIGHT Reaction2668 false L-Aspartic acid → Ammonium + Fumaric acid LEFT_TO_RIGHT Reaction2665 false Adenosine triphosphate + Ammonium + L-Glutamic acid → Adenosine diphosphate + Hydrogen Ion + L-Glutamine + Phosphate LEFT_TO_RIGHT Reaction2666 false Ammonium + Hydrogen Ion + NADPH + Oxoglutaric acid → L-Glutamic acid + NADP + Water LEFT_TO_RIGHT P77454 UniProt CHEBI:15377 ChEBI Sodium CHEBI:15378 ChEBI SMILES [H+] NADP-specific glutamate dehydrogenase Glutamine-binding periplasmic protein SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound 1.0 1.0 280 PubChem-compound CHEBI:30744 ChEBI 2.0 16741146 PubChem-compound Aspartate aminotransferase SMILES N[C@@H](CCC(N)=O)C(O)=O glutamate synthase 1.0 1.0 1061 PubChem-compound Hydrogen Ion 1.0 P00509 UniProt 1.0 ReactionCatalysis2481 ACTIVATION Putative sulfate transporter ychM Anaerobic C4- dicarboxylate transporter dcuC Anaerobic C4- dicarboxylate transporter dcuA Anaerobic C4- dicarboxylate transporter dcuB Aerobic C4- dicarboxylate transport protein Sodium/glutamate symport carrier protein Proton glutamate symport protein Glutamine synthetase glutaminase 2 glutaminase 1 NADP-specific glutamate dehydrogenase Aspartate aminotransferase Aspartate ammonia-lyase Glutamate synthase [NADPH] large chain Glutamate synthase [NADPH] small chain Glutamate decarboxylase beta Glutamate decarboxylase alpha Glutamate/aspartate transport ATP-binding protein gltL Glutamate/aspartate transport system permease protein gltK Glutamate/aspartate transport system permease protein gltJ Glutamate/aspartate periplasmic- binding protein Glutamine transport ATP-binding protein glnQ Glutamine transport system permease protein glnP Glutamine- binding periplasmic protein Glutamine transport ATP-binding protein glnQ Glutamine transport system permease protein glnP Glutamine- binding periplasmic protein Fumaric acid Fumaric acid Fumaric acid Fumaric acid Succinic acid Succinic acid Fumaric acid Fumaric acid H + H + L-Glutamic acid L-Glutamic acid Na + Na + H + H + L-Glutamic acid L-Glutamic acid L-Glutamic acid ATP Ammonium L-Glutamine H + ADP P i L-Glutamine H 2 O NH 3 Oxoglutaric acid NADPH Ammonium H + H 2 O NADP L-Glutamic acid Oxalacetic acid L-Aspartic acid Oxoglutaric acid Fumaric acid Ammonium L-Glutamine Oxoglutaric acid NADPH H + NADP H + CO 2 4- (Glutamylamino) butanoate L-Glutamic acid ATP H 2 O ADP P i H + L-Glutamic acid L-Glutamine ATP H 2 O ADP P i H + L-Glutamine L-Glutamine ATP H 2 O ADP P i H + L-Glutamine Glutaric acid pyrimidine metabolism TCA cycle
CHEBI:16015 ChEBI HMDB00254 HMDB Glutamate/aspartate transport system permease protein gltK HMDB00134 HMDB 6022 PubChem-compound 923 PubChem-compound 937 ChemSpider CHEBI:16134 ChEBI HMDB01341 HMDB P69910 UniProt 110-17-8 CAS 50 ChemSpider 1.0 Glutamate decarboxylase alpha 1.0 HMDB00148 HMDB P0AC38 UniProt OXALACETIC_ACID BioCyc Glutamate synthase [NADPH] small chain ATP BioCyc Glutamate/aspartate periplasmic-binding protein H4N Ammonium 18.034374 1.0 Glutamate synthase [NADPH] large chain P69908 UniProt Transport369 false L-Glutamic acid (→), Sodium (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 1.0 5746 ChemSpider 1.0 5745 ChemSpider Transport371 false Hydrogen Ion (→), L-Glutamic acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 5742 ChemSpider L-ASPARTATE BioCyc Glutamate/aspartate transport system permease protein gltJ CHEBI:16474 ChEBI Glutamate decarboxylase beta HMDB59597 HMDB Aerobic C4-dicarboxylate transport protein 945 ChemSpider Proton glutamate symport protein Glutamine synthetase 1010 ChemSpider 2.0 HMDB41827 HMDB Glutamate/aspartate transport ATP-binding protein gltL 23724570 PubChem-compound BiologicalState109 Escherichia coli, Inner Membrane 1.0 5105-96-4 CAS Ammonium ReactionCoupledTransportCatalysis136 ACTIVATION C5H10N2O3 L-Glutamine 146.06914 Hydrogen Ion SubPathwayInteraction1527 SubPathway1527Reaction SubPathwayReaction HMDB00217 HMDB SubPathwayInteraction1526 SubPathwayReaction SubPathway1526Reaction Cytosol Adenosine triphosphate SUC BioCyc Glutamine transport ATP-binding protein glnQ CHEBI:49260 ChEBI HMDB00208 HMDB C00009 KEGG Compound HMDB00221 HMDB C00008 KEGG Compound HMDB00223 HMDB C00006 KEGG Compound HMDB00588 HMDB 1.0 CHEBI:18009 ChEBI P0ABN5 UniProt Hydrogen Ion C00001 KEGG Compound C00122 KEGG Compound C01330 KEGG Compound ReactionCoupledTransportCatalysis141 ACTIVATION P0A6W0 UniProt C00005 KEGG Compound Glutamate/aspartate transport ATP-binding protein gltL CPD-9000 BioCyc CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound ReactionCoupledTransport107 false Adenosine triphosphate + L-Glutamine + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamine + Phosphate LEFT_TO_RIGHT Anaerobic C4-dicarboxylate transporter dcuC Anaerobic C4-dicarboxylate transporter dcuB HMDB01429 HMDB ReactionCoupledTransport102 false Adenosine triphosphate + L-Glutamic acid + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamic acid + Phosphate LEFT_TO_RIGHT 44367445 PubChem-compound C01342 KEGG Compound C00011 KEGG Compound glutaminase 1 C00014 KEGG Compound NAD(P) BioCyc glutaminase 2 562 TAXONOMY P0ABP1 UniProt H Hydrogen Ion 1.007825 P09832 UniProt P0ABP4 UniProt P09831 UniProt L-Glutamine 56-65-5 CAS Glutamate/aspartate periplasmic-binding protein L-Glutamic acid 1.0 C00026 KEGG Compound C00025 KEGG Compound ReactionCatalysis5119 ACTIVATION 1.0 CHEBI:29101 ChEBI Glutamine transport system permease protein glnP P0AAG3 UniProt C00036 KEGG Compound 899 ChemSpider 328-50-7 CAS Water SMILES OC(=O)CCC(O)=O 2.0 C15767 KEGG Compound P0AFR2 UniProt C00042 KEGG Compound C00049 KEGG Compound 56-85-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Anaerobic C4-dicarboxylate transporter dcuA HMDB00538 HMDB 17341-25-2 CAS 10197150 ChemSpider P0AEQ3 UniProt P0AEQ6 UniProt FUM BioCyc SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS CHEBI:18012 ChEBI Aspartate ammonia-lyase Glutamine transport system permease protein glnP AMMONIA BioCyc SMILES N 56-86-0 CAS HMDB00641 HMDB P0AER3 UniProt C10H16N5O13P3 Adenosine triphosphate 506.99576 P0AER5 UniProt CHEBI:17053 ChEBI 1.0 P0AER8 UniProt C00064 KEGG Compound Sodium/glutamate symport carrier protein Glutamate/aspartate transport system permease protein gltK L-Glutamic acid Glutamate/aspartate transport system permease protein gltJ HMDB01967 HMDB 962 PubChem-compound 5800 ChemSpider glutamine ABC transporter 4.0 Sodium CO2 Carbon dioxide 43.98983 SMILES N[C@@H](CCC(=O)NCCCC(O)=O)C(O)=O Phosphate C00080 KEGG Compound Periplasmic Space Oxoglutaric acid TransportCatalysis317 ACTIVATION TransportCatalysis315 ACTIVATION SMILES N[C@@H](CCC(O)=O)C(O)=O 14265-44-2 CAS 58-64-0 CAS Putative sulfate transporter ychM Glutamine transport ATP-binding protein glnQ L-Aspartic acid 1.0 Transport448 false Fumaric acid (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C4H7NO4 L-Aspartic acid 133.0375 Transport447 false Fumaric acid (→), Succinic acid (←) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport446 false Fumaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Fumaric acid Glutamine synthetase 22833512 PubChem-compound CHEBI:18050 ChEBI H2O Water 18.010565 Proton glutamate symport protein Aerobic C4-dicarboxylate transport protein Na Sodium 22.989769 L-Glutamic acid Carbon dioxide 56-84-8 CAS 21865667 ChemSpider 970 PubChem-compound SMILES OC(=O)\C=C\C(O)=O P0A830 UniProt 1.0 Adenosine diphosphate Reaction5146 false Hydrogen Ion + L-Glutamic acid → 4-(Glutamylamino) butanoate + Carbon dioxide LEFT_TO_RIGHT 1.0 30572 ChemSpider 17215925 ChemSpider C4H4O5 Oxalacetic acid 132.00587 L-Glutamine aspartate ammonia-lyase aspartate transaminase dicarboxylate transporter ReactionCatalysis2659 ACTIVATION ReactionCatalysis2658 ACTIVATION 21883788 PubChem-compound SMILES O H3N Ammonia 17.026548 SMILES [Na+] 5961 PubChem-compound http://identifiers.org/smpdb/SMP00959 SMPDB 1.0 1.0 328-42-7 CAS 51 PubChem-compound ReactionCatalysis2660 ACTIVATION Succinic acid ADP BioCyc ReactionCatalysis2662 ACTIVATION ReactionCatalysis2661 ACTIVATION P00370 UniProt 53-59-8 CAS 1038 PubChem-compound glutamate / aspartate ABC transporter glutamate decarboxylase 2.0 GO:0005829 GENE ONTOLOGY Ammonia 274 ChemSpider C5H6O5 Oxoglutaric acid 146.02153 NADP-specific glutamate dehydrogenase 1.0 Aspartate aminotransferase O4P Phosphate 94.95342 Oxalacetic acid NADPH GO:0070258 GENE ONTOLOGY NADP TCA cycle SubPathway C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 PW000942 PathWhiz L-alanine metabolism SubPathway NADPH BioCyc Fumaric acid 218 ChemSpider 217 ChemSpider L-Glutamic acid SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O CHEBI:30915 ChEBI 124-38-9 CAS PW000779 PathWhiz Hydrogen Ion 4-(Glutamylamino) butanoate Inner Membrane SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O Fumaric acid 1.0 GLN BioCyc GLT BioCyc 7664-41-7 CAS C4H4O4 Fumaric acid 116.010956 Anaerobic C4-dicarboxylate transporter dcuA 53-57-6 CAS TransportCatalysis385 ACTIVATION Glutamate decarboxylase alpha 1.0 TransportCatalysis384 ACTIVATION http://identifiers.org/smpdb/SMP00802 SMPDB TransportCatalysis383 ACTIVATION CHEBI:15741 ChEBI 1.0 1.0 Glutamate synthase [NADPH] large chain Glutamate synthase [NADPH] small chain SMILES O=C=O CHEBI:28938 ChEBI 222 PubChem-compound 1110 PubChem-compound Sodium/glutamate symport carrier protein Aspartate ammonia-lyase 5957 PubChem-compound L-glutamate metabolism GO:0005620 GENE ONTOLOGY C4H6O4 Succinic acid 118.02661 1.0 http://identifiers.org/smpdb/SMP00810 SMPDB http://identifiers.org/smpdb/SMP00811 SMPDB Glutamate decarboxylase beta Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 SMILES N[C@@H](CC(O)=O)C(O)=O glutaminase Glutamine-binding periplasmic protein Adenosine triphosphate CPD-8587 BioCyc Putative sulfate transporter ychM Phosphate P37902 UniProt 1.0 5675 ChemSpider 1078 ChemSpider 14798-03-9 CAS Water CHEBI:15422 ChEBI SubPathwayInteraction1505 SubPathway1505Reaction SubPathwayReaction HMDB00191 HMDB C9H16N2O5 4-(Glutamylamino) butanoate 232.10593 Anaerobic C4-dicarboxylate transporter dcuC Anaerobic C4-dicarboxylate transporter dcuB 1.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound SMILES [NH4+] P10346 UniProt 1.0 CHEBI:16526 ChEBI glutaminase 1 glutaminase 2 1.0 CHEBI:16761 ChEBI P21345 UniProt Succinic acid PW000789 PathWhiz 3.5.1.2 false 3.5.1.2 L-Glutamine + Water → Ammonia + L-Glutamic acid LEFT_TO_RIGHT PW000788 PathWhiz pyrimidine metabolism SubPathway 2-KETOGLUTARATE BioCyc P0A9C5 UniProt HMDB00051 HMDB 1.0 1.0 HMDB02111 HMDB 110-15-6 CAS HMDB12161 HMDB 1.0 Reaction2669 false Hydrogen Ion + L-Glutamine + NADPH + Oxoglutaric acid → 2 L-Glutamic acid + NADP LEFT_TO_RIGHT Reaction2667 false L-Glutamic acid + Oxalacetic acid → L-Aspartic acid + Oxoglutaric acid LEFT_TO_RIGHT Reaction2668 false L-Aspartic acid → Ammonium + Fumaric acid LEFT_TO_RIGHT Reaction2665 false Adenosine triphosphate + Ammonium + L-Glutamic acid → Adenosine diphosphate + Hydrogen Ion + L-Glutamine + Phosphate LEFT_TO_RIGHT Reaction2666 false Ammonium + Hydrogen Ion + NADPH + Oxoglutaric acid → L-Glutamic acid + NADP + Water LEFT_TO_RIGHT P77454 UniProt CHEBI:15377 ChEBI Sodium CHEBI:15378 ChEBI SMILES [H+] NADP-specific glutamate dehydrogenase Glutamine-binding periplasmic protein SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound 1.0 1.0 280 PubChem-compound CHEBI:30744 ChEBI 2.0 16741146 PubChem-compound Aspartate aminotransferase SMILES N[C@@H](CCC(N)=O)C(O)=O glutamate synthase 1.0 1.0 1061 PubChem-compound Hydrogen Ion 1.0 P00509 UniProt 1.0 ReactionCatalysis2481 ACTIVATION ychM dcuC dcuA dcuB dctA gltS gltP glnA glsB glsA gdhA aspC aspA gltB gltD gadB gadA gltL gltK gltJ gltI glnQ glnP glnH glnQ glnP glnH Fumaric acid Fumaric acid Fumaric acid Fumaric acid Succinic acid Succinic acid Fumaric acid Fumaric acid Hydrogen Ion Hydrogen Ion L-Glutamic acid L-Glutamic acid Sodium Sodium Hydrogen Ion Hydrogen Ion L-Glutamic acid L-Glutamic acid L-Glutamic acid Adenosine triphosphate Ammonium L-Glutamine Hydrogen Ion Adenosine diphosphate Phosphate L-Glutamine Water Ammonia Oxoglutaric acid NADPH Ammonium Hydrogen Ion Water NADP L-Glutamic acid Oxalacetic acid L-Aspartic acid Oxoglutaric acid Fumaric acid Ammonium L-Glutamine Oxoglutaric acid NADPH Hydrogen Ion NADP Hydrogen Ion Carbon dioxide 4- (Glutamylamino) butanoate L-Glutamic acid Adenosine triphosphate Water Adenosine diphosphate Phosphate Hydrogen Ion L-Glutamic acid L-Glutamine Adenosine triphosphate Water Adenosine diphosphate Phosphate Hydrogen Ion L-Glutamine L-Glutamine Adenosine triphosphate Water Adenosine diphosphate Phosphate Hydrogen Ion L-Glutamine Glutaric acid pyrimidine metabolism TCA cycle