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P0ABQ2 UniProt D-Glucaric acid 17215925 ChemSpider 6022 PubChem-compound 2553-59-5 CAS HMDB00139 HMDB C23H38N7O17P3S Acetyl-CoA 809.1258 2-Dehydro-3-deoxy-D-glucarate 937 ChemSpider HMDB01341 HMDB Reaction3674 false 2-Phosphoglyceric acid ↔ Phosphoenolpyruvic acid + Water REVERSIBLE NADH phosphoenolpyruvate synthetase 58 ChemSpider 439153 PubChem-compound enolase 1.0 SMILES O pyruvate kinase C10H14N5O7P Adenosine monophosphate 347.06308 1.0 Glucarate dehydratase 473-81-4 CAS Reaction3675 false Adenosine triphosphate + Pyruvic acid + Water → Adenosine monophosphate + 2 Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid LEFT_TO_RIGHT CHEBI:16027 ChEBI NAD Pyruvate kinase I ATP BioCyc 1005 PubChem-compound 5-dehydro-4-deoxy-D-glucarate(2−) HMDB00263 HMDB 1122 PubChem-compound 1.2.4.1 false 1.2.4.1 Coenzyme A + NAD + Pyruvic acid → Acetyl-CoA + Carbon dioxide + NADH LEFT_TO_RIGHT 1.0 6816 PubChem-compound 1.0 Pyruvic acid SMILES OC(C(O)C(O)C(O)=O)C(O)C(O)=O CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 59 PubChem-compound ReactionCatalysis2542 ACTIVATION 388334 ChemSpider 1.0 53-59-8 CAS 1.0 C6H6O7 5-dehydro-4-deoxy-D-glucarate(2−) 190.01135 HMDB01206 HMDB 1.0 5742 ChemSpider 1038 PubChem-compound CHEBI:16474 ChEBI GO:0005829 GENE ONTOLOGY Pyruvate kinase II 440165 PubChem-compound HMDB59597 HMDB 274 ChemSpider Adenosine monophosphate C6H10O8 Galactaric acid 210.03757 HMDB00902 HMDB P0AD61 UniProt CHEBI:16908 ChEBI P39829 UniProt HMDB00243 HMDB 5858 ChemSpider C6H8O7 2-Dehydro-3-deoxy-D-glucarate 192.02701 O4P Phosphate 94.95342 CHEBI:32398 ChEBI Acetyl-CoA NADPH 1.0 1010 ChemSpider HMDB00362 HMDB 1.0 2-Phosphoglyceric acid SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Reaction5867 false D-Glucaric acid → 2-Dehydro-3-deoxy-D-glucarate + Water LEFT_TO_RIGHT ReactionCatalysis5833 ACTIVATION NADP C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 C3H7O7P 2-Phosphoglyceric acid 185.99294 1.0 138-08-9 CAS P0AES2 UniProt 1.0 1.0 NADPH BioCyc HMDB01423 HMDB Hydrogen Ion HMDB00217 HMDB D-galactarate dehydratase Cytosol Enolase Adenosine triphosphate 58-68-4 CAS Glucarate dehydratase SMILES [O-]P([O-])([O-])=O SMILES O[C@@H]([C@@H](O)[C@H](O)C(O)=O)[C@@H](O)C(O)=O 124-38-9 CAS PW000779 PathWhiz TransportCatalysis399 ACTIVATION TransportCatalysis398 ACTIVATION Glyceric acid TransportCatalysis397 ACTIVATION HMDB00221 HMDB C00009 KEGG Compound C00008 KEGG Compound C00006 KEGG Compound CHEBI:18009 ChEBI C00001 KEGG Compound 439194 PubChem-compound C00005 KEGG Compound C00004 KEGG Compound CHEBI:18367 ChEBI C00003 KEGG Compound 1032 ChemSpider TCA cycle SubPathway 1031 ChemSpider C00002 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O SMILES OCC(OP(O)(O)=O)C(O)=O SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O D-Glucaric acid HMDB01429 HMDB 526-99-8 CAS 2-hydroxy-3-oxopropionate reductase 53-57-6 CAS SMP00802 SMPDB 2.7.1.165 false 2.7.1.165 Adenosine triphosphate + Glyceric acid → 2-Phosphoglyceric acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT C21H28N7O14P2 NAD 664.11694 4.1.2.20 false 4.1.2.20 5-dehydro-4-deoxy-D-glucarate(2−) → Pyruvic acid + Tartronate semialdehyde LEFT_TO_RIGHT Reaction2727 false Hydrogen Ion + NADPH + Tartronate semialdehyde → Glyceric acid + NADP LEFT_TO_RIGHT SubPathwayInteraction1664 SubPathway1664Reaction SubPathwayReaction C00011 KEGG Compound SMILES O=C=O C00010 KEGG Compound Probable glucarate transporter C00258 KEGG Compound 1.0 1.0 ReactionCatalysis2634 ACTIVATION NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound Probable galactarate transporter 4.2.1.40 false 4.2.1.40 D-Glucaric acid → 5-dehydro-4-deoxy-D-glucarate(2−) + Water LEFT_TO_RIGHT GO:0005620 GENE ONTOLOGY 4.2.1.42 false 4.2.1.42 Galactaric acid → 5-dehydro-4-deoxy-D-glucarate(2−) + Water LEFT_TO_RIGHT CHEBI:24344 ChEBI TransportCatalysis396 ACTIVATION H Hydrogen Ion 1.007825 HMDB29881 HMDB C00022 KEGG Compound Unknown 56-65-5 CAS 53-84-9 CAS C00020 KEGG Compound SMP00816 SMPDB Pyruvate kinase II 3037582 PubChem-compound Unknown C00024 KEGG Compound Adenosine diphosphate 587 ChemSpider C3H5O6P Phosphoenolpyruvic acid 167.98238 C10H15N5O10P2 Adenosine diphosphate 427.02942 2.0 2301286 ChemSpider 1.0 1.0 Phosphoenolpyruvic acid Q46916 UniProt 1.0 SMILES O[C@@H](CC(=O)C([O-])=O)[C@@H](O)C([O-])=O Glycerate kinase 2 Phosphoenolpyruvate synthase SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc 5-keto-4-deoxy-D-glucarate aldolase 5682 ChemSpider Unknown SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Water AMP BioCyc 1090 ChemSpider SMILES [H][C@](O)(CC(=O)C(O)=O)[C@]([H])(O)C(O)=O D-glucarate and D-galactarate degradation CO-A BioCyc D-galactarate dehydratase 5675 ChemSpider 72-89-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A 2-hydroxy-3-oxopropionate reductase C21H36N7O16P3S Coenzyme A 767.11523 PHOSPHO-ENOL-PYRUVATE BioCyc HMDB00538 HMDB 24.0 SMILES OC(=O)C(=C)OP(O)(O)=O CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS 1.0 388299 ChemSpider CHEBI:16992 ChEBI C01146 KEGG Compound ReactionCatalysis2710 ACTIVATION 61-19-8 CAS P21599 UniProt P23538 UniProt SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 ReactionCatalysis2711 ACTIVATION 127-17-3 CAS 1.0 ReactionCatalysis2714 ACTIVATION C3H6O4 Glyceric acid 106.02661 ReactionCatalysis2713 ACTIVATION Galactaric acid ReactionCatalysis2715 ACTIVATION P0AA81 UniProt 2.7.1.40 false 2.7.1.40 Adenosine diphosphate + Hydrogen Ion + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid LEFT_TO_RIGHT C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 PW000795 PathWhiz Probable glucarate transporter CHEBI:16526 ChEBI 4.0 Probable galactarate transporter 1.0 87-73-0 CAS CHEBI:16761 ChEBI C3H4O4 Tartronate semialdehyde 104.010956 SMILES CC(=O)C(O)=O P23524 UniProt P23522 UniProt C00074 KEGG Compound Tartronate semialdehyde HMDB01967 HMDB HMDB00639 HMDB 962 PubChem-compound Unknown Unknown CHEBI:17305 ChEBI C00879 KEGG Compound 5800 ChemSpider 392413 ChemSpider Galactaric acid 2480-77-5 CAS 1.0 CO2 Carbon dioxide 43.98983 Phosphate 5893 PubChem-compound 1.0 HMDB02111 HMDB C00080 KEGG Compound 4.0 Periplasmic Space Pyruvate dehydrogenase complex Pyruvate kinase I 1.0 607 PubChem-compound SMILES OC[C@@H](O)C(O)=O 1.0 CHEBI:32816 ChEBI CHEBI:1139229 ChEBI ReactionCatalysis3662 ACTIVATION ReactionCatalysis3663 ACTIVATION CHEBI:15377 ChEBI C00767 KEGG Compound CHEBI:15378 ChEBI SMILES [H+] CHEBI:44897 ChEBI 14265-44-2 CAS PYRUVATE BioCyc Phosphoenolpyruvate synthase Glycerate kinase 2 5-keto-4-deoxy-D-glucarate aldolase 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 60.0 5886 PubChem-compound Unknown 1.0 SMILES OC(C=O)C(O)=O 280 PubChem-compound Galactaric acid 2.0 HMDB01487 HMDB HMDB06938 HMDB 444493 PubChem-compound 6083 PubChem-compound 2-PG BioCyc CHEBI:30852 ChEBI 22833512 PubChem-compound ACETYL-COA BioCyc 60.0 H2O Water 18.010565 NADH BioCyc NAD BioCyc 2.0 1060 PubChem-compound Transport462 false D-Glucaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT HMDB00045 HMDB 1061 PubChem-compound Transport464 false Galactaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport463 false D-Glucaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Carbon dioxide CHEBI:15351 ChEBI CHEBI:42819 ChEBI Enolase 980 ChemSpider C6H10O8 D-Glucaric acid 210.03757 D-Glucaric acid 85-61-0 CAS P0A6P9 UniProt Transport465 false Galactaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Probable galactarate transporter Probable glucarate transporter Probable galactarate transporter Probable glucarate transporter D-galactarate dehydratase Glucarate dehydratase 5-keto-4- deoxy-D- glucarate aldolase 2-hydroxy-3- oxopropionate reductase Glycerate kinase 2 Unknown Unknown Unknown Enolase Pyruvate kinase I Pyruvate kinase II Phosphoenolpyruvate synthase Glucarate dehydratase D-Glucaric acid D-Glucaric acid D-Glucaric acid D-Glucaric acid Galactaric acid Galactaric acid Galactaric acid Galactaric acid Galactaric acid H 2 O 5-dehydro-4- deoxy-D- glucarate(2−) D-Glucaric acid H 2 O Pyruvic acid Tartronate semialdehyde H + NADPH NADP Glyceric acid ATP H + ADP 2- Phosphoglyceric acid CoA NAD Acetyl-CoA CO 2 NADH H 2 O Phosphoenolpyruvic acid ADP H + ATP Pyruvic acid H 2 O ATP AMP P i H + Phosphoenolpyruvic acid H 2 O 2-Dehydro-3- deoxy-D- glucarate TCA cycle Unknown
P0ABQ2 UniProt D-Glucaric acid 17215925 ChemSpider 6022 PubChem-compound 2553-59-5 CAS HMDB00139 HMDB C23H38N7O17P3S Acetyl-CoA 809.1258 2-Dehydro-3-deoxy-D-glucarate 937 ChemSpider HMDB01341 HMDB Reaction3674 false 2-Phosphoglyceric acid ↔ Phosphoenolpyruvic acid + Water REVERSIBLE NADH phosphoenolpyruvate synthetase 58 ChemSpider 439153 PubChem-compound enolase 1.0 SMILES O pyruvate kinase C10H14N5O7P Adenosine monophosphate 347.06308 1.0 Glucarate dehydratase 473-81-4 CAS Reaction3675 false Adenosine triphosphate + Pyruvic acid + Water → Adenosine monophosphate + 2 Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid LEFT_TO_RIGHT CHEBI:16027 ChEBI NAD Pyruvate kinase I ATP BioCyc 1005 PubChem-compound 5-dehydro-4-deoxy-D-glucarate(2−) HMDB00263 HMDB 1122 PubChem-compound 1.2.4.1 false 1.2.4.1 Coenzyme A + NAD + Pyruvic acid → Acetyl-CoA + Carbon dioxide + NADH LEFT_TO_RIGHT 1.0 6816 PubChem-compound 1.0 Pyruvic acid SMILES OC(C(O)C(O)C(O)=O)C(O)C(O)=O CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 59 PubChem-compound ReactionCatalysis2542 ACTIVATION 388334 ChemSpider 1.0 53-59-8 CAS 1.0 C6H6O7 5-dehydro-4-deoxy-D-glucarate(2−) 190.01135 HMDB01206 HMDB 1.0 5742 ChemSpider 1038 PubChem-compound CHEBI:16474 ChEBI GO:0005829 GENE ONTOLOGY Pyruvate kinase II 440165 PubChem-compound HMDB59597 HMDB 274 ChemSpider Adenosine monophosphate C6H10O8 Galactaric acid 210.03757 HMDB00902 HMDB P0AD61 UniProt CHEBI:16908 ChEBI P39829 UniProt HMDB00243 HMDB 5858 ChemSpider C6H8O7 2-Dehydro-3-deoxy-D-glucarate 192.02701 O4P Phosphate 94.95342 CHEBI:32398 ChEBI Acetyl-CoA NADPH 1.0 1010 ChemSpider HMDB00362 HMDB 1.0 2-Phosphoglyceric acid SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Reaction5867 false D-Glucaric acid → 2-Dehydro-3-deoxy-D-glucarate + Water LEFT_TO_RIGHT ReactionCatalysis5833 ACTIVATION NADP TCA cycle SubPathway C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 C3H7O7P 2-Phosphoglyceric acid 185.99294 1.0 138-08-9 CAS P0AES2 UniProt 1.0 1.0 NADPH BioCyc HMDB01423 HMDB Hydrogen Ion HMDB00217 HMDB D-galactarate dehydratase Cytosol Enolase Adenosine triphosphate 58-68-4 CAS Glucarate dehydratase SMILES [O-]P([O-])([O-])=O SMILES O[C@@H]([C@@H](O)[C@H](O)C(O)=O)[C@@H](O)C(O)=O 124-38-9 CAS PW000779 PathWhiz TransportCatalysis399 ACTIVATION TransportCatalysis398 ACTIVATION Glyceric acid TransportCatalysis397 ACTIVATION HMDB00221 HMDB C00009 KEGG Compound C00008 KEGG Compound C00006 KEGG Compound CHEBI:18009 ChEBI C00001 KEGG Compound 439194 PubChem-compound C00005 KEGG Compound C00004 KEGG Compound CHEBI:18367 ChEBI C00003 KEGG Compound 1032 ChemSpider 1031 ChemSpider C00002 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O SMILES OCC(OP(O)(O)=O)C(O)=O SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O D-Glucaric acid HMDB01429 HMDB 526-99-8 CAS 2-hydroxy-3-oxopropionate reductase 53-57-6 CAS http://identifiers.org/smpdb/SMP00802 SMPDB 2.7.1.165 false 2.7.1.165 Adenosine triphosphate + Glyceric acid → 2-Phosphoglyceric acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT C21H28N7O14P2 NAD 664.11694 4.1.2.20 false 4.1.2.20 5-dehydro-4-deoxy-D-glucarate(2−) → Pyruvic acid + Tartronate semialdehyde LEFT_TO_RIGHT Reaction2727 false Hydrogen Ion + NADPH + Tartronate semialdehyde → Glyceric acid + NADP LEFT_TO_RIGHT SubPathwayInteraction1664 SubPathway1664Reaction SubPathwayReaction C00011 KEGG Compound SMILES O=C=O C00010 KEGG Compound Probable glucarate transporter C00258 KEGG Compound 1.0 1.0 ReactionCatalysis2634 ACTIVATION NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound Probable galactarate transporter 4.2.1.40 false 4.2.1.40 D-Glucaric acid → 5-dehydro-4-deoxy-D-glucarate(2−) + Water LEFT_TO_RIGHT GO:0005620 GENE ONTOLOGY 4.2.1.42 false 4.2.1.42 Galactaric acid → 5-dehydro-4-deoxy-D-glucarate(2−) + Water LEFT_TO_RIGHT CHEBI:24344 ChEBI TransportCatalysis396 ACTIVATION H Hydrogen Ion 1.007825 HMDB29881 HMDB C00022 KEGG Compound Unknown 56-65-5 CAS 53-84-9 CAS C00020 KEGG Compound http://identifiers.org/smpdb/SMP00816 SMPDB Pyruvate kinase II 3037582 PubChem-compound Unknown C00024 KEGG Compound Adenosine diphosphate 587 ChemSpider C3H5O6P Phosphoenolpyruvic acid 167.98238 C10H15N5O10P2 Adenosine diphosphate 427.02942 2.0 2301286 ChemSpider 1.0 1.0 Phosphoenolpyruvic acid Q46916 UniProt 1.0 SMILES O[C@@H](CC(=O)C([O-])=O)[C@@H](O)C([O-])=O Glycerate kinase 2 Phosphoenolpyruvate synthase SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc 5-keto-4-deoxy-D-glucarate aldolase 5682 ChemSpider Unknown SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Water AMP BioCyc 1090 ChemSpider SMILES [H][C@](O)(CC(=O)C(O)=O)[C@]([H])(O)C(O)=O D-glucarate and D-galactarate degradation CO-A BioCyc D-galactarate dehydratase 5675 ChemSpider 72-89-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A 2-hydroxy-3-oxopropionate reductase C21H36N7O16P3S Coenzyme A 767.11523 PHOSPHO-ENOL-PYRUVATE BioCyc HMDB00538 HMDB 24.0 SMILES OC(=O)C(=C)OP(O)(O)=O CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS 1.0 388299 ChemSpider CHEBI:16992 ChEBI C01146 KEGG Compound ReactionCatalysis2710 ACTIVATION 61-19-8 CAS P21599 UniProt P23538 UniProt SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 ReactionCatalysis2711 ACTIVATION 127-17-3 CAS 1.0 ReactionCatalysis2714 ACTIVATION C3H6O4 Glyceric acid 106.02661 ReactionCatalysis2713 ACTIVATION Galactaric acid ReactionCatalysis2715 ACTIVATION P0AA81 UniProt 2.7.1.40 false 2.7.1.40 Adenosine diphosphate + Hydrogen Ion + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid LEFT_TO_RIGHT C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 PW000795 PathWhiz Probable glucarate transporter CHEBI:16526 ChEBI 4.0 Probable galactarate transporter 1.0 87-73-0 CAS CHEBI:16761 ChEBI C3H4O4 Tartronate semialdehyde 104.010956 SMILES CC(=O)C(O)=O P23524 UniProt P23522 UniProt C00074 KEGG Compound Tartronate semialdehyde HMDB01967 HMDB HMDB00639 HMDB 962 PubChem-compound Unknown Unknown CHEBI:17305 ChEBI C00879 KEGG Compound 5800 ChemSpider 392413 ChemSpider Galactaric acid 2480-77-5 CAS 1.0 CO2 Carbon dioxide 43.98983 Phosphate 5893 PubChem-compound 1.0 HMDB02111 HMDB C00080 KEGG Compound 4.0 Periplasmic Space Pyruvate dehydrogenase complex Pyruvate kinase I 1.0 607 PubChem-compound SMILES OC[C@@H](O)C(O)=O 1.0 CHEBI:32816 ChEBI CHEBI:1139229 ChEBI ReactionCatalysis3662 ACTIVATION ReactionCatalysis3663 ACTIVATION CHEBI:15377 ChEBI C00767 KEGG Compound CHEBI:15378 ChEBI SMILES [H+] CHEBI:44897 ChEBI 14265-44-2 CAS PYRUVATE BioCyc Phosphoenolpyruvate synthase Glycerate kinase 2 5-keto-4-deoxy-D-glucarate aldolase 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 60.0 5886 PubChem-compound Unknown 1.0 SMILES OC(C=O)C(O)=O 280 PubChem-compound Galactaric acid 2.0 HMDB01487 HMDB HMDB06938 HMDB 444493 PubChem-compound 6083 PubChem-compound 2-PG BioCyc CHEBI:30852 ChEBI 22833512 PubChem-compound ACETYL-COA BioCyc 60.0 H2O Water 18.010565 NADH BioCyc NAD BioCyc 2.0 1060 PubChem-compound Transport462 false D-Glucaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT HMDB00045 HMDB 1061 PubChem-compound Transport464 false Galactaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport463 false D-Glucaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Carbon dioxide CHEBI:15351 ChEBI CHEBI:42819 ChEBI Enolase 980 ChemSpider C6H10O8 D-Glucaric acid 210.03757 D-Glucaric acid 85-61-0 CAS P0A6P9 UniProt Transport465 false Galactaric acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT garP gudP garP gudP garD gudD garL garR garK Unknown Unknown Unknown eno pykF pykA ppsA gudD D-Glucaric acid D-Glucaric acid D-Glucaric acid D-Glucaric acid Galactaric acid Galactaric acid Galactaric acid Galactaric acid Galactaric acid Water 5-dehydro-4- deoxy-D- glucarate(2−) D-Glucaric acid Water Pyruvic acid Tartronate semialdehyde Hydrogen Ion NADPH NADP Glyceric acid Adenosine triphosphate Hydrogen Ion Adenosine diphosphate 2- Phosphoglyceric acid Coenzyme A NAD Acetyl-CoA Carbon dioxide NADH Water Phosphoenolpyruvic acid Adenosine diphosphate Hydrogen Ion Adenosine triphosphate Pyruvic acid Water Adenosine triphosphate Adenosine monophosphate Phosphate Hydrogen Ion Phosphoenolpyruvic acid Water 2-Dehydro-3- deoxy-D- glucarate TCA cycle