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Pathway Description
Asparagine Biosynthesis
Escherichia coli
Metabolic Pathway
Asparagine is an amino acid used in protein synthesis, specifically the biosynthesis of glycoproteins. In E.coli, L-asparagine can be synthesized from L-aspartic acid by either utilizing asparagine synthetase B with L-glutamine or ammonia. Both reactions are driven by ATP however the reaction with ammonia utilizes both asparagine synthetase B and aspartate-ammonia ligase.
References
Asparagine Biosynthesis References
Willis RC, Woolfolk CA: L-asparagine uptake in Escherichia coli. J Bacteriol. 1975 Sep;123(3):937-45.
Pubmed: 239925
This pathway was propagated using PathWhiz -
Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.
Propagated from PW000813
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