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2-amino-3- ketobutyrate coenzyme A ligase Threonine/serine transporter tdcC Aspartate aminotransferase Lysine- sensitive aspartokinase 3 Aspartate- semialdehyde dehydrogenase Bifunctional aspartokinase/homoserine dehydrogenase 2 Bifunctional aspartokinase/homoserine dehydrogenase 1 Homoserine kinase Threonine synthase serine/threonine protein kinase L-threonine 3-dehydrogenase 2-amino-3- ketobutyrate coenzyme A ligase Aminomalonic acid L-Threonine L-Threonine H + H + L-Glutamic acid Oxalacetic acid L-Aspartic acid Oxoglutaric acid ATP ADP L-Aspartyl-4- phosphate NADPH H + P i NADP L-Aspartate- semialdehyde H + NADPH NADP L-Homoserine ATP ADP H + O- Phosphohomoserine H 2 O P i L-Threonine ATP ADP Hydrogen ion NAD H + NADH L-2-Amino-3- oxobutanoic acid CoA Acetyl-CoA Glycine Pyridoxal 5'-phosphate Calcium Fe2+ Zinc (II) ion Pyridoxal 5'-phosphate a [protein]-(L- serine/L- threonine) a [protein]-(L- serine/L- threonine) phosphate TCA Cycle
kbl tdcC aspC lysC asd metL thrA thrB thrC rdoA tdh kbl Aminomalonic acid L-Threonine L-Threonine Hydrogen Ion Hydrogen Ion L-Glutamic acid Oxalacetic acid L-Aspartic acid Oxoglutaric acid Adenosine triphosphate Adenosine diphosphate L-Aspartyl-4- phosphate NADPH Hydrogen Ion Phosphate NADP L-Aspartate- semialdehyde Hydrogen Ion NADPH NADP L-Homoserine Adenosine triphosphate Adenosine diphosphate Hydrogen Ion O- Phosphohomoserine Water Phosphate L-Threonine Adenosine triphosphate Adenosine diphosphate Hydrogen ion NAD Hydrogen Ion NADH L-2-Amino-3- oxobutanoic acid Coenzyme A Acetyl-CoA Glycine a [protein]-(L- serine/L- threonine) a [protein]-(L- serine/L- threonine) phosphate TCA Cycle