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Branched-chain amino acid transport system 2 carrier protein Threonine dehydratase biosynthetic Acetolactate synthase isozyme 2 large subunit Acetolactate synthase isozyme 2 small subunit Acetolactate synthase isozyme 1 large subunit Acetolactate synthase isozyme 1 small subunit Acetolactate synthase isozyme 3 large subunit Acetolactate synthase isozyme 3 small subunit Ketol-acid reductoisomerase Dihydroxy-acid dehydratase Branched- chain-amino- acid aminotransferase High-affinity branched-chain amino acid transport ATP-binding protein livF High-affinity branched-chain amino acid transport ATP-binding protein livG High-affinity branched-chain amino acid transport system permease protein livH High-affinity branched-chain amino acid transport system permease protein livM Leu/Ile/Val- binding protein L-Isoleucine L-Isoleucine Na + Na + L-Threonine H + H 2 O (2Z)-2- aminobut-2- enoate 2- iminobutanoate H 2 O H + Ammonium 2-Ketobutyric acid H + Pyruvic acid CO 2 (S)-2-Aceto- 2- hydroxybutanoic acid NADPH H + NADP (R) 2,3- Dihydroxy-3- methylvalerate H 2 O 3-Methyl-2- oxovaleric acid L-Glutamic acid Oxoglutaric acid L-Isoleucine 2-Keto-3- methyl- valerate L-Isoleucine ATP H 2 O L-Isoleucine ADP P i H + Threonine Biosynthesis
brnQ ilvA ilvG ilvM ilvB ilvN ilvI ilvH ilvC ilvD ilvE livF livG livH livM livJ L-Isoleucine L-Isoleucine Sodium Sodium L-Threonine Hydrogen Ion Water (2Z)-2- aminobut-2- enoate 2- iminobutanoate Water Hydrogen Ion Ammonium 2-Ketobutyric acid Hydrogen Ion Pyruvic acid Carbon dioxide (S)-2-Aceto- 2- hydroxybutanoic acid NADPH Hydrogen Ion NADP (R) 2,3- Dihydroxy-3- methylvalerate Water 3-Methyl-2- oxovaleric acid L-Glutamic acid Oxoglutaric acid L-Isoleucine 2-Keto-3- methyl- valerate L-Isoleucine Adenosine triphosphate Water L-Isoleucine Adenosine diphosphate Phosphate Hydrogen Ion Threonine Biosynthesis