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HMDB01586 HMDB 6022 PubChem-compound 1.0 923 PubChem-compound Phosphocarrier protein HPr 937 ChemSpider Galactose-1-phosphate uridylyltransferase HMDB00250 HMDB 2956-16-3 CAS 1.0 388476 ChemSpider ReactionCoupledTransportCatalysis172 ACTIVATION HMDB01341 HMDB Glucose-specific phosphotransferase enzyme IIA component UDP-glucose 4-epimerase LACTOSE BioCyc 1.0 Reaction3557 true alpha-D-glucose-1-phosphate ↔ Glucose 1-phosphate REVERSIBLE Reaction3556 false α-D-glucose 6-phosphate → alpha-D-glucose-1-phosphate LEFT_TO_RIGHT 1.0 Reaction3555 true β-D-glucose 1-phosphate ↔ Glucose 1-phosphate REVERSIBLE 6133 PubChem-compound 58238 ChemSpider SMILES O[C@H]1O[C@H](OP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O C00446 KEGG Compound H Hydrogen ion 1.007825 1.0 alpha-D-glucose-1-phosphate Transport361 false Alpha-Lactose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 388480 ChemSpider ATP BioCyc 26502 ChemSpider HMDB00143 HMDB PTS system glucose-specific EIICB component 559142 ChemSpider Lithium HMDB05949 HMDB C6H13O9P alpha-D-glucose-1-phosphate 260.02972 P0AA04 UniProt 1.0 5742 ChemSpider ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc HMDB59597 HMDB 1.0 C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 53477679 PubChem-compound 1.0 133-89-1 CAS C00221 KEGG Compound C00103 KEGG Compound 1010 ChemSpider Aldose 1-epimerase 439165 PubChem-compound 1.0 PPI BioCyc 1.0 BiologicalState109 C6H13O9P Galactose 1-phosphate 260.02972 ReactionCatalysis3260 ACTIVATION Hydrogen Ion 59-56-3 CAS Cytosol UTP--glucose-1-phosphate uridylyltransferase_ 388311 ChemSpider glucose PTS permease Adenosine triphosphate 1.0 Galactokinase 10239175 PubChem-compound Phosphoglucomutase-1 5.4.2.6 false 5.4.2.6 Beta-D-Glucose 6-phosphate → β-D-glucose 1-phosphate LEFT_TO_RIGHT 1.0 Transport399 false Beta-D-Galactose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Lithium C00008 KEGG Compound SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O HMDB00588 HMDB Hydrogen Ion 389538 ChemSpider C00243 KEGG Compound C00001 KEGG Compound C01330 KEGG Compound CHEBI:18361 ChEBI Glucokinase C00002 KEGG Compound Phosphocarrier protein HPr P0A6V8 UniProt GLC-1-P BioCyc C6H12O6 Alpha-D-Glucose 180.06339 Hydrogen ion 84571 PubChem-compound 388538 ChemSpider C00013 KEGG Compound 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT Galactose-proton symporter ReactionCoupledTransport133 false Alpha-D-Glucose + HPr - phosphorylated → HPr + α-D-glucose 6-phosphate LEFT_TO_RIGHT 562 TAXONOMY H Hydrogen Ion 1.007825 C00029 KEGG Compound 59-23-4 CAS ReactionCoupledTransportCatalysis167 ACTIVATION Putative beta-phosphoglucomutase 56-65-5 CAS Lactose permease 1.0 1.0 Galactose 1-phosphate C00267 KEGG Compound 2.0 Melibiose carrier protein 1.0 CHEBI:29101 ChEBI 899 ChemSpider Li Lithium 7.016004 Water 123912 PubChem-compound Beta-D-Galactose 492-61-5 CAS PTS system glucose-specific EIICB component SMILES [O-]P([O-])(=O)OP([O-])([O-])=O P0AEP1 UniProt HMDB00302 HMDB P0AEP3 UniProt Uridine diphosphategalactose SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O MELIBIOSE BioCyc 1.0 Beta-D-Galactose C00052 KEGG Compound 1.0 C6H12O6 Beta-D-Galactose 180.06339 HMDB00538 HMDB Transport403 false Melibiose (→), Lithium (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport402 false Melibiose (→), Sodium (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT UTP BioCyc Transport401 false Melibiose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 17341-25-2 CAS 64689 PubChem-compound 5903 ChemSpider ALPHA-N-DIACETYLNEURAMINYL-23-BETA-D-ETC BioCyc CHEBI:28061 ChEBI 18068 PubChem-compound CHEBI:16077 ChEBI 7732-18-5 CAS 1.0 110443 ChemSpider SMILES OC[C@H]1O[C@H](OC[C@H]2OC(O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 3.2.1.22 false 3.2.1.22 Melibiose + Water → Beta-D-Glucose + D-Galactose LEFT_TO_RIGHT 2.7.1.2 false 2.7.1.2 Adenosine triphosphate + Beta-D-Glucose → Adenosine diphosphate + Beta-D-Glucose 6-phosphate + Hydrogen ion LEFT_TO_RIGHT Reaction3296 false Galactose 1-phosphate + Uridine diphosphate glucose → Glucose 1-phosphate + Uridine diphosphategalactose LEFT_TO_RIGHT 1.0 492-62-6 CAS C10H16N5O13P3 Adenosine triphosphate 506.99576 HMDB00645 HMDB 1.0 P0A6T3 UniProt HMDB00516 HMDB CHEBI:28053 ChEBI 17341-24-1 CAS 962 PubChem-compound Beta-D-Glucose 5800 ChemSpider SMILES OC1OC(COP([O-])([O-])=C)C(O)C(O)C1O C00075 KEGG Compound Sodium C05402 KEGG Compound SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O C00080 KEGG Compound PW000819 PathWhiz Periplasmic Space 1.0 C01172 KEGG Compound SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O SMILES O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O C12H22O11 Alpha-Lactose 342.1162 58-64-0 CAS C6H13O9P Glucose 1-phosphate 260.02972 1.0 71358 ChemSpider 2255-14-3 CAS 1.0 644102 PubChem-compound C15H24N2O17P2 Uridine diphosphategalactose 566.055 C15473 KEGG Compound Glucose 1-phosphate Alpha-Lactose Glucose-specific phosphotransferase enzyme IIA component Aldose 1-epimerase H2O Water 18.010565 ReactionCatalysis2914 ACTIVATION galactose metabolism SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O Na Sodium 22.989769 P06720 UniProt Alpha-galactosidase ReactionCatalysis2915 ACTIVATION ReactionCatalysis2918 ACTIVATION CHEBI:58601 ChEBI ReactionCatalysis2919 ACTIVATION ReactionCatalysis2921 ACTIVATION ReactionCatalysis2923 ACTIVATION UTP--glucose-1-phosphate uridylyltransferase_ TransportCatalysis307 ACTIVATION CHEBI:15903 ChEBI SMILES OC[C@H]1O[C@H](O[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O Alpha-Lactose UDP-GLACTOSE BioCyc alpha-galactosidase Galactokinase 1.0 63-42-3 CAS SMILES O Glucokinase Beta-D-Galactose C12H22O11 Melibiose 342.1162 Pyrophosphate C6H12O6 Beta-D-Glucose 180.06339 SMILES [Na+] GALACTOSE-1P BioCyc SMP00839 SMPDB CHEBI:58225 ChEBI 1.0 Melibiose ADP BioCyc SMP00841 SMPDB SMILES [Li+] 1038 PubChem-compound Alpha-D-Glucose GO:0005829 GENE ONTOLOGY Lactose permease Melibiose Beta-D-Glucose CHEBI:15713 ChEBI CHEBI:58247 ChEBI GO:0070258 GENE ONTOLOGY SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O TransportCatalysis347 ACTIVATION PW000821 PathWhiz TransportCatalysis346 ACTIVATION TransportCatalysis345 ACTIVATION TransportCatalysis343 ACTIVATION alpha-D-glucose 6 phosphate 2.7.7.9 false 2.7.7.9 Glucose 1-phosphate + Hydrogen Ion + Uridine triphosphate → Pyrophosphate + Uridine diphosphate glucose LEFT_TO_RIGHT Reaction2946 true β-D-glucose 6-phosphate → α-D-glucose 6-phosphate LEFT_TO_RIGHT 5.4.2.2 false 5.4.2.2 alpha-D-glucose 6 phosphate → α-D-glucose 1-phosphate LEFT_TO_RIGHT Beta-galactosidase CHEBI:57684 ChEBI 1.0 C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc C9H15N2O15P3 Uridine triphosphate 483.96854 1.0 β-galactosidase 585-99-9 CAS UDP-glucose 4-epimerase CHEBI:36219 ChEBI galactose-1-phosphate uridylyltransferase 28486 PubChem-compound D-Galactose 7296-64-2 CAS CHEBI:67119 ChEBI UDP-glucose 4-epimerase β-D-glucose 6-phosphate Galactose-1-phosphate uridylyltransferase α-D-glucose 6-phosphate 2.0 α-D-glucose 1-phosphate P69783 UniProt Inner Membrane P69786 UniProt 1.0 CHEBI:49713 ChEBI 2.0 1.0 P09147 UniProt P09148 UniProt C7H13O8P β-D-glucose 6-phosphate 256.0359 C6H11O9P α-D-glucose 6-phosphate 258.01517 α-D-glucose 1-phosphate O7P2 Pyrophosphate 173.91193 Uridine diphosphate glucose 5957 PubChem-compound GO:0005620 GENE ONTOLOGY Uridine triphosphate Beta-D-Glucose 6-phosphate C6H13O9P alpha-D-glucose 6 phosphate 260.02972 SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O SMILES OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O 1.0 Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 P36871 UniProt 3.2.1.23 false 3.2.1.23 Alpha-Lactose + Water → Beta-D-Galactose + Beta-D-Glucose LEFT_TO_RIGHT CHEBI:17925 ChEBI Reaction2954 false Beta-D-Galactose → D-Galactose LEFT_TO_RIGHT 5.1.3.2 false 5.1.3.2 Uridine diphosphate glucose ↔ Uridine diphosphategalactose REVERSIBLE 2.7.1.6 false 2.7.1.6 Adenosine triphosphate + D-Galactose → Adenosine diphosphate + Galactose 1-phosphate + Hydrogen Ion LEFT_TO_RIGHT β-D-glucose 1-phosphate 76293 ChemSpider 14000-31-8 CAS 1.0 440658 PubChem-compound C00962 KEGG Compound Phosphoglucomutase-1 HMDB03498 HMDB 1.0 CHEBI:27667 ChEBI 1.0 α-D-glucose 6-phosphate 439427 PubChem-compound P77366 UniProt HMDB03345 HMDB GALACTOSE BioCyc CHEBI:15422 ChEBI Alpha-galactosidase C6H12O6 D-Galactose 180.06339 Gluconeogenesis from L-malic acid SubPathway Alpha-Lactose CHEBI:17719 ChEBI LI%2b BioCyc CHEBI:17973 ChEBI C5H9O9P β-D-glucose 1-phosphate 243.99951 SubPathwayInteraction1515 SubPathwayReaction SubPathway1515Reaction C00984 KEGG Compound Galactose-proton symporter CHEBI:16761 ChEBI ReactionCatalysis3259 ACTIVATION 17069 ChemSpider ReactionCatalysis3258 ACTIVATION CHEBI:17665 ChEBI P0A9C3 UniProt Putative beta-phosphoglucomutase HMDB03449 HMDB Beta-D-Glucose 6-phosphate Melibiose carrier protein 1.0 1.0 HMDB02111 HMDB 439357 PubChem-compound ReactionCatalysis3546 ACTIVATION 439353 PubChem-compound CHEBI:15377 ChEBI Sodium CHEBI:15378 ChEBI SMILES [H+] SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB00186 HMDB 1.0 79025 PubChem-compound P00722 UniProt 2.0 SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O 4.0 ReactionCatalysis3321 ACTIVATION 63-39-8 CAS SMILES [H+] 1.0 HMDB00048 HMDB Hydrogen Ion 1.0 HMDB00285 HMDB Melibiose HMDB00286 HMDB Beta-galactosidase SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 P02920 UniProt P02921 UniProt SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O Lactose permease Galactose- proton symporter Melibiose carrier protein Melibiose carrier protein Melibiose carrier protein Phosphoglucomutase- 1 UTP--glucose- 1-phosphate uridylyltransferase_ UDP-glucose 4-epimerase UTP--glucose- 1-phosphate uridylyltransferase_ Galactokinase Aldose 1-epimerase Beta- galactosidase Galactose-1- phosphate uridylyltransferase Glucokinase Alpha- galactosidase Putative beta- phosphoglucomutase Phosphoglucomutase- 1 Phosphocarrier protein HPr Phosphocarrier protein HPr PTS system glucose- specific EIICB component Glucose- specific phosphotransferase enzyme IIA component Phosphocarrier protein HPr Phosphocarrier protein HPr PTS system glucose- specific EIICB component Glucose- specific phosphotransferase enzyme IIA component Alpha-Lactose Alpha-Lactose H + H + Beta-D- Galactose Beta-D- Galactose H + H + Melibiose Melibiose H + H + Melibiose Na + Na + Melibiose Lithium Lithium β-D-glucose 6-phosphate α-D-glucose 6-phosphate alpha-D-glucose 6 phosphate α-D-glucose 1-phosphate Glucose 1-phosphate Uridine triphosphate H + PP i Uridine diphosphate glucose Uridine diphosphate glucose Uridine diphosphategalactose Glucose 1-phosphate Uridine triphosphate H + PP i D-Galactose ATP ADP H + Galactose 1-phosphate Beta-D- Galactose H 2 O Beta-D-Glucose Uridine diphosphate glucose Uridine diphosphategalactose Glucose 1-phosphate Beta-D-Glucose ATP Hydrogen ion ADP Beta-D-Glucose 6-phosphate H 2 O D-Galactose Beta-D-Glucose Beta-D-Glucose 6-phosphate β-D-glucose 1-phosphate Glucose 1-phosphate α-D-glucose 6-phosphate alpha-D- glucose-1- phosphate Glucose 1-phosphate Alpha-D-Glucose Beta-D-Glucose Gluconeogenesis from L-malic acid
HMDB01586 HMDB 6022 PubChem-compound 1.0 923 PubChem-compound Phosphocarrier protein HPr 937 ChemSpider Galactose-1-phosphate uridylyltransferase HMDB00250 HMDB 2956-16-3 CAS 1.0 388476 ChemSpider ReactionCoupledTransportCatalysis172 ACTIVATION HMDB01341 HMDB Glucose-specific phosphotransferase enzyme IIA component UDP-glucose 4-epimerase LACTOSE BioCyc 1.0 Reaction3557 true alpha-D-glucose-1-phosphate ↔ Glucose 1-phosphate REVERSIBLE Reaction3556 false α-D-glucose 6-phosphate → alpha-D-glucose-1-phosphate LEFT_TO_RIGHT 1.0 Reaction3555 true β-D-glucose 1-phosphate ↔ Glucose 1-phosphate REVERSIBLE 6133 PubChem-compound 58238 ChemSpider SMILES O[C@H]1O[C@H](OP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O C00446 KEGG Compound H Hydrogen ion 1.007825 1.0 alpha-D-glucose-1-phosphate Transport361 false Alpha-Lactose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 388480 ChemSpider ATP BioCyc 26502 ChemSpider HMDB00143 HMDB PTS system glucose-specific EIICB component 559142 ChemSpider Lithium HMDB05949 HMDB C6H13O9P alpha-D-glucose-1-phosphate 260.02972 P0AA04 UniProt 1.0 5742 ChemSpider ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc HMDB59597 HMDB 1.0 C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 53477679 PubChem-compound 1.0 133-89-1 CAS C00221 KEGG Compound C00103 KEGG Compound 1010 ChemSpider Aldose 1-epimerase 439165 PubChem-compound 1.0 PPI BioCyc 1.0 BiologicalState109 Escherichia coli, Inner Membrane C6H13O9P Galactose 1-phosphate 260.02972 ReactionCatalysis3260 ACTIVATION Hydrogen Ion 59-56-3 CAS Cytosol UTP--glucose-1-phosphate uridylyltransferase_ 388311 ChemSpider glucose PTS permease Adenosine triphosphate 1.0 Galactokinase 10239175 PubChem-compound Phosphoglucomutase-1 5.4.2.6 false 5.4.2.6 Beta-D-Glucose 6-phosphate → β-D-glucose 1-phosphate LEFT_TO_RIGHT 1.0 Transport399 false Beta-D-Galactose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Lithium C00008 KEGG Compound SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O HMDB00588 HMDB Hydrogen Ion 389538 ChemSpider C00243 KEGG Compound C00001 KEGG Compound C01330 KEGG Compound CHEBI:18361 ChEBI Glucokinase C00002 KEGG Compound Phosphocarrier protein HPr P0A6V8 UniProt GLC-1-P BioCyc C6H12O6 Alpha-D-Glucose 180.06339 Hydrogen ion 84571 PubChem-compound 388538 ChemSpider C00013 KEGG Compound 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT Galactose-proton symporter ReactionCoupledTransport133 false Alpha-D-Glucose + HPr - phosphorylated → HPr + α-D-glucose 6-phosphate LEFT_TO_RIGHT 562 TAXONOMY H Hydrogen Ion 1.007825 C00029 KEGG Compound 59-23-4 CAS ReactionCoupledTransportCatalysis167 ACTIVATION Putative beta-phosphoglucomutase 56-65-5 CAS Lactose permease 1.0 1.0 Galactose 1-phosphate C00267 KEGG Compound 2.0 Melibiose carrier protein 1.0 CHEBI:29101 ChEBI 899 ChemSpider Li Lithium 7.016004 Water 123912 PubChem-compound Beta-D-Galactose 492-61-5 CAS PTS system glucose-specific EIICB component SMILES [O-]P([O-])(=O)OP([O-])([O-])=O P0AEP1 UniProt HMDB00302 HMDB P0AEP3 UniProt Uridine diphosphategalactose SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O MELIBIOSE BioCyc 1.0 Beta-D-Galactose C00052 KEGG Compound 1.0 C6H12O6 Beta-D-Galactose 180.06339 HMDB00538 HMDB Transport403 false Melibiose (→), Lithium (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport402 false Melibiose (→), Sodium (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT UTP BioCyc Transport401 false Melibiose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 17341-25-2 CAS 64689 PubChem-compound 5903 ChemSpider ALPHA-N-DIACETYLNEURAMINYL-23-BETA-D-ETC BioCyc CHEBI:28061 ChEBI 18068 PubChem-compound CHEBI:16077 ChEBI 7732-18-5 CAS 1.0 110443 ChemSpider SMILES OC[C@H]1O[C@H](OC[C@H]2OC(O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 3.2.1.22 false 3.2.1.22 Melibiose + Water → Beta-D-Glucose + D-Galactose LEFT_TO_RIGHT 2.7.1.2 false 2.7.1.2 Adenosine triphosphate + Beta-D-Glucose → Adenosine diphosphate + Beta-D-Glucose 6-phosphate + Hydrogen ion LEFT_TO_RIGHT Reaction3296 false Galactose 1-phosphate + Uridine diphosphate glucose → Glucose 1-phosphate + Uridine diphosphategalactose LEFT_TO_RIGHT 1.0 492-62-6 CAS C10H16N5O13P3 Adenosine triphosphate 506.99576 HMDB00645 HMDB 1.0 P0A6T3 UniProt HMDB00516 HMDB CHEBI:28053 ChEBI 17341-24-1 CAS 962 PubChem-compound Beta-D-Glucose 5800 ChemSpider SMILES OC1OC(COP([O-])([O-])=C)C(O)C(O)C1O C00075 KEGG Compound Sodium C05402 KEGG Compound SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O C00080 KEGG Compound PW000819 PathWhiz Periplasmic Space 1.0 C01172 KEGG Compound SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O SMILES O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O C12H22O11 Alpha-Lactose 342.1162 58-64-0 CAS C6H13O9P Glucose 1-phosphate 260.02972 1.0 71358 ChemSpider 2255-14-3 CAS 1.0 644102 PubChem-compound C15H24N2O17P2 Uridine diphosphategalactose 566.055 C15473 KEGG Compound Glucose 1-phosphate Alpha-Lactose Glucose-specific phosphotransferase enzyme IIA component Aldose 1-epimerase H2O Water 18.010565 ReactionCatalysis2914 ACTIVATION galactose metabolism SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O Na Sodium 22.989769 P06720 UniProt Alpha-galactosidase ReactionCatalysis2915 ACTIVATION ReactionCatalysis2918 ACTIVATION CHEBI:58601 ChEBI ReactionCatalysis2919 ACTIVATION ReactionCatalysis2921 ACTIVATION ReactionCatalysis2923 ACTIVATION UTP--glucose-1-phosphate uridylyltransferase_ TransportCatalysis307 ACTIVATION CHEBI:15903 ChEBI SMILES OC[C@H]1O[C@H](O[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O Alpha-Lactose UDP-GLACTOSE BioCyc alpha-galactosidase Galactokinase 1.0 63-42-3 CAS SMILES O Glucokinase Beta-D-Galactose C12H22O11 Melibiose 342.1162 Pyrophosphate C6H12O6 Beta-D-Glucose 180.06339 SMILES [Na+] GALACTOSE-1P BioCyc http://identifiers.org/smpdb/SMP00839 SMPDB CHEBI:58225 ChEBI 1.0 Melibiose ADP BioCyc http://identifiers.org/smpdb/SMP00841 SMPDB SMILES [Li+] 1038 PubChem-compound Alpha-D-Glucose GO:0005829 GENE ONTOLOGY Lactose permease Melibiose Beta-D-Glucose CHEBI:15713 ChEBI CHEBI:58247 ChEBI GO:0070258 GENE ONTOLOGY SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O TransportCatalysis347 ACTIVATION PW000821 PathWhiz TransportCatalysis346 ACTIVATION TransportCatalysis345 ACTIVATION TransportCatalysis343 ACTIVATION alpha-D-glucose 6 phosphate 2.7.7.9 false 2.7.7.9 Glucose 1-phosphate + Hydrogen Ion + Uridine triphosphate → Pyrophosphate + Uridine diphosphate glucose LEFT_TO_RIGHT Reaction2946 true β-D-glucose 6-phosphate → α-D-glucose 6-phosphate LEFT_TO_RIGHT 5.4.2.2 false 5.4.2.2 alpha-D-glucose 6 phosphate → α-D-glucose 1-phosphate LEFT_TO_RIGHT Beta-galactosidase CHEBI:57684 ChEBI 1.0 C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc C9H15N2O15P3 Uridine triphosphate 483.96854 1.0 β-galactosidase 585-99-9 CAS UDP-glucose 4-epimerase CHEBI:36219 ChEBI galactose-1-phosphate uridylyltransferase 28486 PubChem-compound D-Galactose 7296-64-2 CAS CHEBI:67119 ChEBI UDP-glucose 4-epimerase β-D-glucose 6-phosphate Galactose-1-phosphate uridylyltransferase α-D-glucose 6-phosphate 2.0 α-D-glucose 1-phosphate P69783 UniProt Inner Membrane P69786 UniProt 1.0 CHEBI:49713 ChEBI 2.0 1.0 P09147 UniProt P09148 UniProt C7H13O8P β-D-glucose 6-phosphate 256.0359 C6H11O9P α-D-glucose 6-phosphate 258.01517 α-D-glucose 1-phosphate O7P2 Pyrophosphate 173.91193 Uridine diphosphate glucose 5957 PubChem-compound GO:0005620 GENE ONTOLOGY Uridine triphosphate Beta-D-Glucose 6-phosphate C6H13O9P alpha-D-glucose 6 phosphate 260.02972 SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O SMILES OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O 1.0 Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 P36871 UniProt 3.2.1.23 false 3.2.1.23 Alpha-Lactose + Water → Beta-D-Galactose + Beta-D-Glucose LEFT_TO_RIGHT CHEBI:17925 ChEBI Reaction2954 false Beta-D-Galactose → D-Galactose LEFT_TO_RIGHT 5.1.3.2 false 5.1.3.2 Uridine diphosphate glucose ↔ Uridine diphosphategalactose REVERSIBLE 2.7.1.6 false 2.7.1.6 Adenosine triphosphate + D-Galactose → Adenosine diphosphate + Galactose 1-phosphate + Hydrogen Ion LEFT_TO_RIGHT β-D-glucose 1-phosphate 76293 ChemSpider 14000-31-8 CAS 1.0 440658 PubChem-compound C00962 KEGG Compound Phosphoglucomutase-1 HMDB03498 HMDB 1.0 CHEBI:27667 ChEBI 1.0 α-D-glucose 6-phosphate 439427 PubChem-compound P77366 UniProt HMDB03345 HMDB GALACTOSE BioCyc CHEBI:15422 ChEBI Alpha-galactosidase Gluconeogenesis from L-malic acid SubPathway C6H12O6 D-Galactose 180.06339 Alpha-Lactose CHEBI:17719 ChEBI LI%2b BioCyc CHEBI:17973 ChEBI C5H9O9P β-D-glucose 1-phosphate 243.99951 SubPathwayInteraction1515 SubPathwayReaction SubPathway1515Reaction C00984 KEGG Compound Galactose-proton symporter CHEBI:16761 ChEBI ReactionCatalysis3259 ACTIVATION 17069 ChemSpider ReactionCatalysis3258 ACTIVATION CHEBI:17665 ChEBI P0A9C3 UniProt Putative beta-phosphoglucomutase HMDB03449 HMDB Beta-D-Glucose 6-phosphate Melibiose carrier protein 1.0 1.0 HMDB02111 HMDB 439357 PubChem-compound ReactionCatalysis3546 ACTIVATION 439353 PubChem-compound CHEBI:15377 ChEBI Sodium CHEBI:15378 ChEBI SMILES [H+] SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB00186 HMDB 1.0 79025 PubChem-compound P00722 UniProt 2.0 SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O 4.0 ReactionCatalysis3321 ACTIVATION 63-39-8 CAS SMILES [H+] 1.0 HMDB00048 HMDB Hydrogen Ion 1.0 HMDB00285 HMDB Melibiose HMDB00286 HMDB Beta-galactosidase SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 P02920 UniProt P02921 UniProt SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O