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L-aspartate oxidase Quinolinate synthase A Nicotinate- nucleotide pyrophosphorylase [carboxylating] Nicotinate- nucleotide adenylyltransferase NH(3)-dependent NAD(+) synthetase NH(3)-dependent NAD(+) synthetase L-Aspartic acid O 2 H 2 O 2 H + Iminoaspartic acid Dihydroxyacetone phosphate P i H 2 O Quinolinic acid H + Phosphoribosyl pyrophosphate CO 2 PP i nicotinate β-D- ribonucleotide ATP H + PP i Nicotinic acid adenine dinucleotide H 2 O L-Glutamine ATP H + AMP PP i L-Glutamic acid NAD ATP Ammonium H + AMP PP i NAD Aspartate Metabolism
nadB nadA nadC nadD nadE nadE L-Aspartic acid Oxygen Hydrogen peroxide Hydrogen Ion Iminoaspartic acid Dihydroxyacetone phosphate Phosphate Water Quinolinic acid Hydrogen Ion Phosphoribosyl pyrophosphate Carbon dioxide Pyrophosphate nicotinate β-D- ribonucleotide Adenosine triphosphate Hydrogen Ion Pyrophosphate Nicotinic acid adenine dinucleotide Water L-Glutamine Adenosine triphosphate Hydrogen Ion Adenosine monophosphate Pyrophosphate L-Glutamic acid NAD Adenosine triphosphate Ammonium Hydrogen Ion Adenosine monophosphate Pyrophosphate NAD Aspartate Metabolism