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CHEBI:16015 ChEBI 1.0 30572 ChemSpider 7722-84-1 CAS L-aspartate oxidase 937 ChemSpider HMDB00250 HMDB Adenosine monophosphate SMILES OO SMILES O C7H5NO4 Quinolinic acid 167.02185 C10H14N5O7P Adenosine monophosphate 347.06308 Quinolinate synthase A 145043 ChemSpider CHEBI:16027 ChEBI HMDB00148 HMDB CHEBI:50616 ChEBI 1.0 ATP BioCyc 5961 PubChem-compound HMDB01473 HMDB CHEBI:17111 ChEBI H4N Ammonium 18.034374 C3H7O6P Dihydroxyacetone phosphate 169.99803 559142 ChemSpider 165491 PubChem-compound CHEBI:15846 ChEBI HMDB00232 HMDB 2.0 5746 ChemSpider 5745 ChemSpider C03722 KEGG Compound 5742 ChemSpider 1038 PubChem-compound SMP00849 SMPDB L-ASPARTATE BioCyc 952 ChemSpider GO:0005829 GENE ONTOLOGY 7540-64-9 CAS HMDB59597 HMDB 274 ChemSpider HMDB00902 HMDB CHEBI:18304 ChEBI 5858 ChemSpider Pyrophosphate O4P Phosphate 94.95342 CHEBI:16240 ChEBI 1010 ChemSpider PW000829 PathWhiz HMDB41827 HMDB PPI BioCyc 2.0 C11H15NO9P nicotinate beta-D-ribonucleotide 336.04843 C00119 KEGG Compound BiologicalState108 CHEBI:15763 ChEBI 1.0 PW000787 PathWhiz Nicotinate-nucleotide pyrophosphorylase [carboxylating] C5H10N2O3 L-Glutamine 146.06914 C00111 KEGG Compound Carbon dioxide Cytosol CPD-6641 BioCyc Nicotinate-nucleotide pyrophosphorylase [carboxylating] Iminoaspartic acid 1.0 218 ChemSpider ReactionCatalysis2974 ACTIVATION ReactionCatalysis2976 ACTIVATION ReactionCatalysis2975 ACTIVATION C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 SMILES [O-]P([O-])([O-])=O ReactionCatalysis2978 ACTIVATION ReactionCatalysis2977 ACTIVATION ReactionCatalysis2979 ACTIVATION 1.0 124-38-9 CAS IMINOASPARTATE BioCyc C00009 KEGG Compound 1037 ChemSpider C00007 KEGG Compound P11458 UniProt 796 PubChem-compound Hydrogen Ion C00001 KEGG Compound 1.0 CHEBI:18361 ChEBI CHEBI:18367 ChEBI 1032 ChemSpider C00003 KEGG Compound C00002 KEGG Compound NH(3)-dependent NAD(+) synthetase GLN BioCyc HMDB01429 HMDB GLT BioCyc 57-04-5 CAS 1.0 C21H28N7O14P2 NAD 664.11694 44367445 PubChem-compound SMP00809 SMPDB C00011 KEGG Compound SMILES O=C=O C01342 KEGG Compound 7339 PubChem-compound CHEBI:28938 ChEBI C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 QUINOLINATE BioCyc Nicotinate-nucleotide adenylyltransferase 6.3.1.5 false 6.3.1.5 Adenosine triphosphate + Ammonium + Nicotinic acid adenine dinucleotide → Adenosine monophosphate + Hydrogen Ion + NAD + Pyrophosphate LEFT_TO_RIGHT 6.3.1.5 false 6.3.1.5 Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water → Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate LEFT_TO_RIGHT 2.7.7.18 false 2.7.7.18 Adenosine triphosphate + Hydrogen Ion + nicotinate beta-D-ribonucleotide → Nicotinic acid adenine dinucleotide + Pyrophosphate LEFT_TO_RIGHT 5957 PubChem-compound 562 TAXONOMY H Hydrogen Ion 1.007825 1.0 SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]4=CC=CC(=C4)C(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS C00027 KEGG Compound L-Glutamic acid C00025 KEGG Compound nicotinate beta-D-ribonucleotide Adenosine triphosphate SMILES N[C@@H](CC(O)=O)C(O)=O 2.4.2.19 false 2.4.2.19 Hydrogen Ion + Phosphoribosyl pyrophosphate + Quinolinic acid → Carbon dioxide + Pyrophosphate + nicotinate beta-D-ribonucleotide LEFT_TO_RIGHT 2.5.1.72 false 2.5.1.72 Dihydroxyacetone phosphate + Iminoaspartic acid → Phosphate + Quinolinic acid + 2 Water LEFT_TO_RIGHT Reaction3007 false L-Aspartic acid + Oxygen → Hydrogen Ion + Hydrogen peroxide + Iminoaspartic acid LEFT_TO_RIGHT HMDB03125 HMDB CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O C05840 KEGG Compound 5682 ChemSpider Dihydroxyacetone phosphate AMP BioCyc HYDROGEN-PEROXIDE BioCyc 108822 ChemSpider SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS Aspartate metabolism SubPathway C00049 KEGG Compound 648 ChemSpider 56-85-9 CAS 763 ChemSpider 7062 ChemSpider SubPathwayInteraction1184 SubPathwayReaction SubPathway1184Reaction P18843 UniProt 14798-03-9 CAS 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)[N+]1=CC=CC(=C1)C(O)=O HMDB00538 HMDB 2.0 1.0 784 PubChem-compound CHEBI:15422 ChEBI C4H5NO4 Iminoaspartic acid 131.02185 668 PubChem-compound C00857 KEGG Compound HMDB00191 HMDB 121992 PubChem-compound quinolinate phosphoribosyltransferase 7732-18-5 CAS 89-00-9 CAS 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 O2 Oxygen 31.98983 SMILES OC(=O)C1=CC=CN=C1C(O)=O 56-86-0 CAS Water C5H9NO4 L-Glutamic acid 147.05316 HMDB01179 HMDB 33032 PubChem-compound NAD SMILES [NH4+] HMDB00641 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 DIHYDROXY-ACETONE-PHOSPHATE BioCyc CHEBI:16526 ChEBI 1.0 CHEBI:17053 ChEBI C00064 KEGG Compound P10902 UniProt 1.0 7782-44-7 CAS P0A752 UniProt SMILES OCC(=O)COP(O)(O)=O HMDB01967 HMDB Nicotinic acid adenine dinucleotide 1.0 962 PubChem-compound 2.0 1.0 quinolinate synthase Hydrogen peroxide CO2 Carbon dioxide 43.98983 5893 PubChem-compound HMDB02111 HMDB C00080 KEGG Compound 6450-77-7 CAS SMILES O=O 1.0 SMILES N[C@@H](CCC(O)=O)C(O)=O CHEBI:15377 ChEBI CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] 79067-61-1 CAS 14265-44-2 CAS CHEBI:16108 ChEBI Quinolinic acid NH(3)-dependent NAD(+) synthetase SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O C21H27N6O15P2 Nicotinic acid adenine dinucleotide 665.10095 Phosphate Oxygen C01185 KEGG Compound 280 PubChem-compound Phosphoribosyl pyrophosphate HMDB59646 HMDB C4H7NO4 L-Aspartic acid 133.0375 CHEBI:16675 ChEBI NAD synthetase, NH3-dependent 644102 PubChem-compound L-Glutamine 6083 PubChem-compound 16741146 PubChem-compound L-aspartate oxidase SMILES N[C@@H](CCC(N)=O)C(O)=O PRPP BioCyc Nicotinate-nucleotide adenylyltransferase NAD biosynthesis L-Aspartic acid CHEBI:18050 ChEBI H2O2 Hydrogen peroxide 34.005478 H2O Water 18.010565 SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O Ammonium 1.0 NAD BioCyc HMDB01377 HMDB HMDB00045 HMDB 1061 PubChem-compound P30011 UniProt 977 PubChem-compound 1.0 56-84-8 CAS HMDB00280 HMDB Quinolinate synthase A HMDB01131 HMDB 1.0 1.0 1066 PubChem-compound 1.0 SMILES OC(=O)CC(=N)C(O)=O DEAMIDO-NAD BioCyc 13628208 ChemSpider L-aspartate oxidase Quinolinate synthase A Nicotinate- nucleotide pyrophosphorylase [carboxylating] Nicotinate- nucleotide adenylyltransferase NH(3)-dependent NAD(+) synthetase NH(3)-dependent NAD(+) synthetase L-Aspartic acid O 2 H 2 O 2 H + Iminoaspartic acid Dihydroxyacetone phosphate P i H 2 O Quinolinic acid H + Phosphoribosyl pyrophosphate CO 2 PP i nicotinate beta-D- ribonucleotide ATP H + PP i Nicotinic acid adenine dinucleotide H 2 O L-Glutamine ATP H + AMP PP i L-Glutamic acid NAD ATP Ammonium H + AMP PP i NAD Aspartate metabolism
CHEBI:16015 ChEBI 1.0 30572 ChemSpider 7722-84-1 CAS L-aspartate oxidase 937 ChemSpider HMDB00250 HMDB Adenosine monophosphate SMILES OO SMILES O C7H5NO4 Quinolinic acid 167.02185 C10H14N5O7P Adenosine monophosphate 347.06308 Quinolinate synthase A 145043 ChemSpider CHEBI:16027 ChEBI HMDB00148 HMDB CHEBI:50616 ChEBI 1.0 ATP BioCyc 5961 PubChem-compound HMDB01473 HMDB CHEBI:17111 ChEBI H4N Ammonium 18.034374 C3H7O6P Dihydroxyacetone phosphate 169.99803 559142 ChemSpider 165491 PubChem-compound CHEBI:15846 ChEBI HMDB00232 HMDB 2.0 5746 ChemSpider 5745 ChemSpider C03722 KEGG Compound 5742 ChemSpider 1038 PubChem-compound http://identifiers.org/smpdb/SMP00849 SMPDB L-ASPARTATE BioCyc 952 ChemSpider GO:0005829 GENE ONTOLOGY 7540-64-9 CAS HMDB59597 HMDB 274 ChemSpider HMDB00902 HMDB CHEBI:18304 ChEBI 5858 ChemSpider Pyrophosphate O4P Phosphate 94.95342 CHEBI:16240 ChEBI 1010 ChemSpider PW000829 PathWhiz HMDB41827 HMDB PPI BioCyc 2.0 C11H15NO9P nicotinate beta-D-ribonucleotide 336.04843 Aspartate metabolism SubPathway C00119 KEGG Compound BiologicalState108 Escherichia coli, Cytosol CHEBI:15763 ChEBI 1.0 PW000787 PathWhiz Nicotinate-nucleotide pyrophosphorylase [carboxylating] C5H10N2O3 L-Glutamine 146.06914 C00111 KEGG Compound Carbon dioxide Cytosol CPD-6641 BioCyc Nicotinate-nucleotide pyrophosphorylase [carboxylating] Iminoaspartic acid 1.0 218 ChemSpider ReactionCatalysis2974 ACTIVATION ReactionCatalysis2976 ACTIVATION ReactionCatalysis2975 ACTIVATION C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 SMILES [O-]P([O-])([O-])=O ReactionCatalysis2978 ACTIVATION ReactionCatalysis2977 ACTIVATION ReactionCatalysis2979 ACTIVATION 1.0 124-38-9 CAS IMINOASPARTATE BioCyc C00009 KEGG Compound 1037 ChemSpider C00007 KEGG Compound P11458 UniProt 796 PubChem-compound Hydrogen Ion C00001 KEGG Compound 1.0 CHEBI:18361 ChEBI CHEBI:18367 ChEBI 1032 ChemSpider C00003 KEGG Compound C00002 KEGG Compound NH(3)-dependent NAD(+) synthetase GLN BioCyc HMDB01429 HMDB GLT BioCyc 57-04-5 CAS 1.0 C21H28N7O14P2 NAD 664.11694 44367445 PubChem-compound http://identifiers.org/smpdb/SMP00809 SMPDB C00011 KEGG Compound SMILES O=C=O C01342 KEGG Compound 7339 PubChem-compound CHEBI:28938 ChEBI C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 QUINOLINATE BioCyc Nicotinate-nucleotide adenylyltransferase 6.3.1.5 false 6.3.1.5 Adenosine triphosphate + Ammonium + Nicotinic acid adenine dinucleotide → Adenosine monophosphate + Hydrogen Ion + NAD + Pyrophosphate LEFT_TO_RIGHT 6.3.1.5 false 6.3.1.5 Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water → Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate LEFT_TO_RIGHT 2.7.7.18 false 2.7.7.18 Adenosine triphosphate + Hydrogen Ion + nicotinate beta-D-ribonucleotide → Nicotinic acid adenine dinucleotide + Pyrophosphate LEFT_TO_RIGHT 5957 PubChem-compound 562 TAXONOMY H Hydrogen Ion 1.007825 1.0 SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]4=CC=CC(=C4)C(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS C00027 KEGG Compound L-Glutamic acid C00025 KEGG Compound nicotinate beta-D-ribonucleotide Adenosine triphosphate SMILES N[C@@H](CC(O)=O)C(O)=O 2.4.2.19 false 2.4.2.19 Hydrogen Ion + Phosphoribosyl pyrophosphate + Quinolinic acid → Carbon dioxide + Pyrophosphate + nicotinate beta-D-ribonucleotide LEFT_TO_RIGHT 2.5.1.72 false 2.5.1.72 Dihydroxyacetone phosphate + Iminoaspartic acid → Phosphate + Quinolinic acid + 2 Water LEFT_TO_RIGHT Reaction3007 false L-Aspartic acid + Oxygen → Hydrogen Ion + Hydrogen peroxide + Iminoaspartic acid LEFT_TO_RIGHT HMDB03125 HMDB CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O C05840 KEGG Compound 5682 ChemSpider Dihydroxyacetone phosphate AMP BioCyc HYDROGEN-PEROXIDE BioCyc 108822 ChemSpider SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS C00049 KEGG Compound 648 ChemSpider 56-85-9 CAS 763 ChemSpider 7062 ChemSpider SubPathwayInteraction1184 SubPathwayReaction SubPathway1184Reaction P18843 UniProt 14798-03-9 CAS 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)[N+]1=CC=CC(=C1)C(O)=O HMDB00538 HMDB 2.0 1.0 784 PubChem-compound CHEBI:15422 ChEBI C4H5NO4 Iminoaspartic acid 131.02185 668 PubChem-compound C00857 KEGG Compound HMDB00191 HMDB 121992 PubChem-compound quinolinate phosphoribosyltransferase 7732-18-5 CAS 89-00-9 CAS 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 O2 Oxygen 31.98983 SMILES OC(=O)C1=CC=CN=C1C(O)=O 56-86-0 CAS Water C5H9NO4 L-Glutamic acid 147.05316 HMDB01179 HMDB 33032 PubChem-compound NAD SMILES [NH4+] HMDB00641 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 DIHYDROXY-ACETONE-PHOSPHATE BioCyc CHEBI:16526 ChEBI 1.0 CHEBI:17053 ChEBI C00064 KEGG Compound P10902 UniProt 1.0 7782-44-7 CAS P0A752 UniProt SMILES OCC(=O)COP(O)(O)=O HMDB01967 HMDB Nicotinic acid adenine dinucleotide 1.0 962 PubChem-compound 2.0 1.0 quinolinate synthase Hydrogen peroxide CO2 Carbon dioxide 43.98983 5893 PubChem-compound HMDB02111 HMDB C00080 KEGG Compound 6450-77-7 CAS SMILES O=O 1.0 SMILES N[C@@H](CCC(O)=O)C(O)=O CHEBI:15377 ChEBI CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] 79067-61-1 CAS 14265-44-2 CAS CHEBI:16108 ChEBI Quinolinic acid NH(3)-dependent NAD(+) synthetase SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O C21H27N6O15P2 Nicotinic acid adenine dinucleotide 665.10095 Phosphate Oxygen C01185 KEGG Compound 280 PubChem-compound Phosphoribosyl pyrophosphate HMDB59646 HMDB C4H7NO4 L-Aspartic acid 133.0375 CHEBI:16675 ChEBI NAD synthetase, NH3-dependent 644102 PubChem-compound L-Glutamine 6083 PubChem-compound 16741146 PubChem-compound L-aspartate oxidase SMILES N[C@@H](CCC(N)=O)C(O)=O PRPP BioCyc Nicotinate-nucleotide adenylyltransferase NAD biosynthesis L-Aspartic acid CHEBI:18050 ChEBI H2O2 Hydrogen peroxide 34.005478 H2O Water 18.010565 SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O Ammonium 1.0 NAD BioCyc HMDB01377 HMDB HMDB00045 HMDB 1061 PubChem-compound P30011 UniProt 977 PubChem-compound 1.0 56-84-8 CAS HMDB00280 HMDB Quinolinate synthase A HMDB01131 HMDB 1.0 1.0 1066 PubChem-compound 1.0 SMILES OC(=O)CC(=N)C(O)=O DEAMIDO-NAD BioCyc 13628208 ChemSpider nadB nadA nadC nadD nadE nadE L-Aspartic acid Oxygen Hydrogen peroxide Hydrogen Ion Iminoaspartic acid Dihydroxyacetone phosphate Phosphate Water Quinolinic acid Hydrogen Ion Phosphoribosyl pyrophosphate Carbon dioxide Pyrophosphate nicotinate beta-D- ribonucleotide Adenosine triphosphate Hydrogen Ion Pyrophosphate Nicotinic acid adenine dinucleotide Water L-Glutamine Adenosine triphosphate Hydrogen Ion Adenosine monophosphate Pyrophosphate L-Glutamic acid NAD Adenosine triphosphate Ammonium Hydrogen Ion Adenosine monophosphate Pyrophosphate NAD Aspartate metabolism