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Pyrazinamidase/nicotinamidase Nicotinate phosphoribosyltransferase NMN amidohydrolase Nicotinate- nucleotide adenylyltransferase NH(3)-dependent NAD(+) synthetase Transcriptional regulator nadR Transcriptional regulator nadR NAD H 2 O H + AMP β-nicotinamide D- ribonucleotide H 2 O H + D-ribofuranose 5-phosphate Niacinamide H 2 O Ammonium Nicotinic acid H 2 O ATP Phosphoribosyl pyrophosphate P i ADP PP i nicotinate β-D- ribonucleotide H 2 O Ammonium nicotinate β-D- ribonucleotide ATP H + PP i Nicotinic acid adenine dinucleotide H 2 O L-Glutamine ATP H + AMP PP i L-Glutamic acid NAD β-nicotinamide D- ribonucleotide H 2 O P i Nicotinamide riboside ATP ADP H + β-nicotinamide D- ribonucleotide ATP H + PP i NAD NADP H 2 O P i NAD NAD Biosynthesis
pncA pncB pncC nadD nadE nadR nadR NAD Water Hydrogen Ion Adenosine monophosphate β-nicotinamide D- ribonucleotide Water Hydrogen Ion D-ribofuranose 5-phosphate Niacinamide Water Ammonium Nicotinic acid Water Adenosine triphosphate Phosphoribosyl pyrophosphate Phosphate Adenosine diphosphate Pyrophosphate nicotinate β-D- ribonucleotide Water Ammonium nicotinate β-D- ribonucleotide Adenosine triphosphate Hydrogen Ion Pyrophosphate Nicotinic acid adenine dinucleotide Water L-Glutamine Adenosine triphosphate Hydrogen Ion Adenosine monophosphate Pyrophosphate L-Glutamic acid NAD β-nicotinamide D- ribonucleotide Water Phosphate Nicotinamide riboside Adenosine triphosphate Adenosine diphosphate Hydrogen Ion β-nicotinamide D- ribonucleotide Adenosine triphosphate Hydrogen Ion Pyrophosphate NAD NADP Water Phosphate NAD NAD Biosynthesis