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CHEBI:16015 ChEBI 30572 ChemSpider 1.0 6022 PubChem-compound P27278 UniProt 937 ChemSpider HMDB00250 HMDB HMDB01341 HMDB Nicotinic acid Adenosine monophosphate NH(3)-dependent NAD(+) synthetase SMILES O C03150 KEGG Compound 13554 ChemSpider C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate 1.0 CHEBI:16027 ChEBI 145043 ChemSpider HMDB00148 HMDB C5H9O8P D-ribofuranose 5-phosphate 228.00461 NAD ATP BioCyc 5961 PubChem-compound H4N Ammonium 18.034374 CHEBI:17111 ChEBI beta-nicotinamide D-ribonucleotide 1.0 1.0 559142 ChemSpider 165491 PubChem-compound CHEBI:15846 ChEBI NAD salvage ADP BioCyc CHEBI:15940 ChEBI 53-59-8 CAS 5746 ChemSpider 1.0 5742 ChemSpider 1038 PubChem-compound SMP00849 SMPDB Transcriptional regulator nadR GO:0005829 GENE ONTOLOGY SMILES NC(=O)C1=CC=CN=C1 7540-64-9 CAS HMDB59597 HMDB Adenosine monophosphate HMDB00902 HMDB Nicotinate-nucleotide adenylyltransferase Pyrazinamidase/nicotinamidase 5858 ChemSpider CHEBI:18304 ChEBI PW000830 PathWhiz Pyrophosphate O4P Phosphate 94.95342 1010 ChemSpider SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O PW000829 PathWhiz HMDB41827 HMDB NADP PPI BioCyc nicotinate beta-D-ribonucleotide 938 PubChem-compound SMP00850 SMPDB C11H16N2O8P beta-nicotinamide D-ribonucleotide 335.06442 936 PubChem-compound C11H15NO9P nicotinate beta-D-ribonucleotide 336.04843 C21H29N7O17P3 NADP 744.08325 beta-nicotinamide D-ribonucleotide C00119 KEGG Compound BiologicalState108 1.0 Nicotinic acid Ammonium CHEBI:15763 ChEBI 1.0 Hydrogen Ion C5H10N2O3 L-Glutamine 146.06914 1.0 HMDB00217 HMDB Cytosol 218 ChemSpider 1.0 1.0 NAD biosynthesis SubPathway Adenosine triphosphate L-Glutamic acid C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 Nicotinate phosphoribosyltransferase SMILES [O-]P([O-])([O-])=O ReactionCatalysis2978 ACTIVATION 1.0 C00009 KEGG Compound C00008 KEGG Compound C00006 KEGG Compound 1.0 Hydrogen Ion CHEBI:18009 ChEBI C00001 KEGG Compound 1.0 CHEBI:18361 ChEBI CHEBI:18367 ChEBI 4.0 C00003 KEGG Compound CHEBI:17154 ChEBI 1032 ChemSpider C00002 KEGG Compound NH(3)-dependent NAD(+) synthetase SubPathwayInteraction1650 SubPathwayReaction SubPathway1650Reaction P21369 UniProt SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O ReactionCatalysis2985 ACTIVATION ReactionCatalysis2984 ACTIVATION 1.0 GLN BioCyc HMDB01429 HMDB GLT BioCyc ReactionCatalysis2981 ACTIVATION ReactionCatalysis2980 ACTIVATION ReactionCatalysis2983 ACTIVATION ReactionCatalysis2982 ACTIVATION C21H28N7O14P2 NAD 664.11694 C01342 KEGG Compound C00253 KEGG Compound CHEBI:28938 ChEBI 7339 PubChem-compound 913 ChemSpider D-ribofuranose 5-phosphate 911 ChemSpider C00013 KEGG Compound Reaction3014 true Water + beta-nicotinamide D-ribonucleotide → D-ribofuranose 5-phosphate + Hydrogen Ion + Niacinamide LEFT_TO_RIGHT Reaction3013 true NAD + Water → Adenosine monophosphate + 2 Hydrogen Ion + beta-nicotinamide D-ribonucleotide LEFT_TO_RIGHT Pyrazinamidase/nicotinamidase O7P2 Pyrophosphate 173.91193 Nicotinate-nucleotide adenylyltransferase 6.3.1.5 false 6.3.1.5 Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water → Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate LEFT_TO_RIGHT NAD(P) BioCyc C6H5NO2 Nicotinic acid 123.03203 5957 PubChem-compound CHEBI:14648 ChEBI Reaction3019 false NADP + Water → NAD + Phosphate LEFT_TO_RIGHT 2.7.7.18 false 2.7.7.18 Adenosine triphosphate + Hydrogen Ion + nicotinate beta-D-ribonucleotide → Nicotinic acid adenine dinucleotide + Pyrophosphate LEFT_TO_RIGHT 3.5.1.42 false 3.5.1.42 Water + beta-nicotinamide D-ribonucleotide → Ammonium + nicotinate beta-D-ribonucleotide LEFT_TO_RIGHT 562 TAXONOMY 6.3.4.21 false 6.3.4.21 Adenosine triphosphate + Nicotinic acid + Phosphoribosyl pyrophosphate + Water → Adenosine diphosphate + Phosphate + Pyrophosphate + nicotinate beta-D-ribonucleotide LEFT_TO_RIGHT 3.5.1.- false 3.5.1.- Niacinamide + Water → Ammonium + Nicotinic acid LEFT_TO_RIGHT P0A6G3 UniProt H Hydrogen Ion 1.007825 1.0 SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]4=CC=CC(=C4)C(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 L-Glutamine 56-65-5 CAS 53-84-9 CAS C00020 KEGG Compound C00025 KEGG Compound Adenosine diphosphate nicotinate beta-D-ribonucleotide Adenosine triphosphate 14181 PubChem-compound C10H15N5O10P2 Adenosine diphosphate 427.02942 HMDB01406 HMDB 1.0 1.0 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O C00153 KEGG Compound CPD-8587 BioCyc 2.0 5682 ChemSpider C6H6N2O Niacinamide 122.04801 AMP BioCyc Water CHEBI:52742 ChEBI 108822 ChemSpider SMILES OC(=O)C1=CN=CC=C1 2.0 Nicotinate phosphoribosyltransferase SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS 1.0 5675 ChemSpider 56-85-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 7062 ChemSpider Reaction3023 false Adenosine triphosphate + Hydrogen Ion + beta-nicotinamide D-ribonucleotide → NAD + Pyrophosphate LEFT_TO_RIGHT 1.0 2.7.7.1 false 2.7.7.1 Adenosine triphosphate + Nicotinamide riboside → Adenosine diphosphate + Hydrogen Ion + beta-nicotinamide D-ribonucleotide LEFT_TO_RIGHT Adenosine diphosphate P18843 UniProt Reaction3021 false Water + beta-nicotinamide D-ribonucleotide → Nicotinamide riboside + Phosphate LEFT_TO_RIGHT 14798-03-9 CAS NMN amidohydrolase Nicotinamide riboside HMDB00538 HMDB SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)[N+]1=CC=CC(=C1)C(O)=O SMILES [H][C@]1(COP(O)(O)=O)O[C@@]([H])([N+]2=CC=CC(=C2)C(O)=N)[C@]([H])(O)[C@]1([H])O 1.0 C11H15N2O5 Nicotinamide riboside 255.0981 CHEBI:15422 ChEBI C00857 KEGG Compound 121992 PubChem-compound 7732-18-5 CAS NIACINAMIDE BioCyc 1.0 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 NICOTINAMIDE_RIBOSE BioCyc Niacinamide 56-86-0 CAS Water C5H9NO4 L-Glutamic acid 147.05316 HMDB01179 HMDB 33032 PubChem-compound NAD SMILES [NH4+] HMDB00641 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 59-67-6 CAS C00064 KEGG Compound CHEBI:16761 ChEBI P0A752 UniProt 1.0 962 PubChem-compound 388956 ChemSpider 5800 ChemSpider HMDB00855 HMDB Phosphate 5893 PubChem-compound 1.0 HMDB02111 HMDB C00080 KEGG Compound 6450-77-7 CAS 1.0 SMILES N[C@@H](CCC(O)=O)C(O)=O 1341-23-7 CAS CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound 1.0 C21H27N6O15P2 Nicotinic acid adenine dinucleotide 665.10095 Phosphate Transcriptional regulator nadR 1.0 1.0 C01185 KEGG Compound Phosphoribosyl pyrophosphate HMDB59646 HMDB HMDB59645 HMDB NAD synthetase, NH3-dependent CHEBI:15927 ChEBI Nicotinic acid adenine dinucleotide HMDB01488 HMDB 644102 PubChem-compound 6083 PubChem-compound 16741146 PubChem-compound SMILES N[C@@H](CCC(N)=O)C(O)=O NMN amidohydrolase PRPP BioCyc P18133 UniProt CHEBI:18050 ChEBI H2O Water 18.010565 SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O NadR DNA-binding transcriptional repressor and NMN adenylyltransferase NAD BioCyc HMDB00045 HMDB 1061 PubChem-compound SMILES OC1OC(COP([O-])([O-])=O)C(O)C1O HMDB00280 HMDB 1.0 NIACINE BioCyc DEAMIDO-NAD BioCyc 98-92-0 CAS 439924 PubChem-compound Pyrazinamidase/nicotinamidase Nicotinate phosphoribosyltransferase NMN amidohydrolase Nicotinate- nucleotide adenylyltransferase NH(3)-dependent NAD(+) synthetase Transcriptional regulator nadR Transcriptional regulator nadR NAD H 2 O H + AMP beta- nicotinamide D- ribonucleotide H 2 O H + D-ribofuranose 5-phosphate Niacinamide H 2 O Ammonium Nicotinic acid H 2 O ATP Phosphoribosyl pyrophosphate P i ADP PP i nicotinate beta-D- ribonucleotide H 2 O Ammonium nicotinate beta-D- ribonucleotide ATP H + PP i Nicotinic acid adenine dinucleotide H 2 O L-Glutamine ATP H + AMP PP i L-Glutamic acid NAD beta- nicotinamide D- ribonucleotide H 2 O P i Nicotinamide riboside ATP ADP H + beta- nicotinamide D- ribonucleotide ATP H + PP i NAD NADP H 2 O P i NAD NAD biosynthesis
CHEBI:16015 ChEBI 30572 ChemSpider 1.0 6022 PubChem-compound P27278 UniProt 937 ChemSpider HMDB00250 HMDB HMDB01341 HMDB Nicotinic acid Adenosine monophosphate NH(3)-dependent NAD(+) synthetase SMILES O C03150 KEGG Compound 13554 ChemSpider C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate 1.0 CHEBI:16027 ChEBI 145043 ChemSpider HMDB00148 HMDB C5H9O8P D-ribofuranose 5-phosphate 228.00461 NAD ATP BioCyc 5961 PubChem-compound H4N Ammonium 18.034374 CHEBI:17111 ChEBI beta-nicotinamide D-ribonucleotide 1.0 1.0 559142 ChemSpider 165491 PubChem-compound CHEBI:15846 ChEBI NAD salvage ADP BioCyc CHEBI:15940 ChEBI 53-59-8 CAS 5746 ChemSpider 1.0 5742 ChemSpider 1038 PubChem-compound http://identifiers.org/smpdb/SMP00849 SMPDB Transcriptional regulator nadR GO:0005829 GENE ONTOLOGY SMILES NC(=O)C1=CC=CN=C1 7540-64-9 CAS HMDB59597 HMDB Adenosine monophosphate HMDB00902 HMDB Nicotinate-nucleotide adenylyltransferase Pyrazinamidase/nicotinamidase 5858 ChemSpider CHEBI:18304 ChEBI PW000830 PathWhiz Pyrophosphate O4P Phosphate 94.95342 1010 ChemSpider SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O PW000829 PathWhiz HMDB41827 HMDB NADP PPI BioCyc nicotinate beta-D-ribonucleotide 938 PubChem-compound http://identifiers.org/smpdb/SMP00850 SMPDB C11H16N2O8P beta-nicotinamide D-ribonucleotide 335.06442 936 PubChem-compound C11H15NO9P nicotinate beta-D-ribonucleotide 336.04843 C21H29N7O17P3 NADP 744.08325 beta-nicotinamide D-ribonucleotide C00119 KEGG Compound BiologicalState108 Escherichia coli, Cytosol 1.0 Nicotinic acid Ammonium CHEBI:15763 ChEBI 1.0 Hydrogen Ion C5H10N2O3 L-Glutamine 146.06914 1.0 HMDB00217 HMDB Cytosol 218 ChemSpider 1.0 1.0 Adenosine triphosphate L-Glutamic acid C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 Nicotinate phosphoribosyltransferase SMILES [O-]P([O-])([O-])=O ReactionCatalysis2978 ACTIVATION 1.0 C00009 KEGG Compound C00008 KEGG Compound C00006 KEGG Compound 1.0 Hydrogen Ion CHEBI:18009 ChEBI C00001 KEGG Compound 1.0 CHEBI:18361 ChEBI CHEBI:18367 ChEBI 4.0 C00003 KEGG Compound CHEBI:17154 ChEBI 1032 ChemSpider C00002 KEGG Compound NH(3)-dependent NAD(+) synthetase SubPathwayInteraction1650 SubPathwayReaction SubPathway1650Reaction P21369 UniProt SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O ReactionCatalysis2985 ACTIVATION ReactionCatalysis2984 ACTIVATION 1.0 GLN BioCyc HMDB01429 HMDB GLT BioCyc ReactionCatalysis2981 ACTIVATION ReactionCatalysis2980 ACTIVATION ReactionCatalysis2983 ACTIVATION ReactionCatalysis2982 ACTIVATION C21H28N7O14P2 NAD 664.11694 C01342 KEGG Compound C00253 KEGG Compound CHEBI:28938 ChEBI 7339 PubChem-compound 913 ChemSpider D-ribofuranose 5-phosphate 911 ChemSpider C00013 KEGG Compound Reaction3014 true Water + beta-nicotinamide D-ribonucleotide → D-ribofuranose 5-phosphate + Hydrogen Ion + Niacinamide LEFT_TO_RIGHT Reaction3013 true NAD + Water → Adenosine monophosphate + 2 Hydrogen Ion + beta-nicotinamide D-ribonucleotide LEFT_TO_RIGHT Pyrazinamidase/nicotinamidase O7P2 Pyrophosphate 173.91193 Nicotinate-nucleotide adenylyltransferase 6.3.1.5 false 6.3.1.5 Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water → Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate LEFT_TO_RIGHT NAD(P) BioCyc C6H5NO2 Nicotinic acid 123.03203 5957 PubChem-compound CHEBI:14648 ChEBI Reaction3019 false NADP + Water → NAD + Phosphate LEFT_TO_RIGHT 2.7.7.18 false 2.7.7.18 Adenosine triphosphate + Hydrogen Ion + nicotinate beta-D-ribonucleotide → Nicotinic acid adenine dinucleotide + Pyrophosphate LEFT_TO_RIGHT 3.5.1.42 false 3.5.1.42 Water + beta-nicotinamide D-ribonucleotide → Ammonium + nicotinate beta-D-ribonucleotide LEFT_TO_RIGHT 562 TAXONOMY 6.3.4.21 false 6.3.4.21 Adenosine triphosphate + Nicotinic acid + Phosphoribosyl pyrophosphate + Water → Adenosine diphosphate + Phosphate + Pyrophosphate + nicotinate beta-D-ribonucleotide LEFT_TO_RIGHT 3.5.1.- false 3.5.1.- Niacinamide + Water → Ammonium + Nicotinic acid LEFT_TO_RIGHT P0A6G3 UniProt H Hydrogen Ion 1.007825 1.0 SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]4=CC=CC(=C4)C(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 L-Glutamine 56-65-5 CAS 53-84-9 CAS C00020 KEGG Compound C00025 KEGG Compound Adenosine diphosphate nicotinate beta-D-ribonucleotide Adenosine triphosphate 14181 PubChem-compound C10H15N5O10P2 Adenosine diphosphate 427.02942 HMDB01406 HMDB 1.0 1.0 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O C00153 KEGG Compound CPD-8587 BioCyc 2.0 5682 ChemSpider C6H6N2O Niacinamide 122.04801 AMP BioCyc Water CHEBI:52742 ChEBI 108822 ChemSpider SMILES OC(=O)C1=CN=CC=C1 2.0 Nicotinate phosphoribosyltransferase SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS 1.0 5675 ChemSpider 56-85-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 7062 ChemSpider Reaction3023 false Adenosine triphosphate + Hydrogen Ion + beta-nicotinamide D-ribonucleotide → NAD + Pyrophosphate LEFT_TO_RIGHT 1.0 2.7.7.1 false 2.7.7.1 Adenosine triphosphate + Nicotinamide riboside → Adenosine diphosphate + Hydrogen Ion + beta-nicotinamide D-ribonucleotide LEFT_TO_RIGHT Adenosine diphosphate P18843 UniProt Reaction3021 false Water + beta-nicotinamide D-ribonucleotide → Nicotinamide riboside + Phosphate LEFT_TO_RIGHT 14798-03-9 CAS NMN amidohydrolase Nicotinamide riboside HMDB00538 HMDB SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)[N+]1=CC=CC(=C1)C(O)=O SMILES [H][C@]1(COP(O)(O)=O)O[C@@]([H])([N+]2=CC=CC(=C2)C(O)=N)[C@]([H])(O)[C@]1([H])O 1.0 C11H15N2O5 Nicotinamide riboside 255.0981 CHEBI:15422 ChEBI C00857 KEGG Compound 121992 PubChem-compound 7732-18-5 CAS NIACINAMIDE BioCyc 1.0 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 NICOTINAMIDE_RIBOSE BioCyc Niacinamide 56-86-0 CAS Water C5H9NO4 L-Glutamic acid 147.05316 HMDB01179 HMDB 33032 PubChem-compound NAD SMILES [NH4+] HMDB00641 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 NAD biosynthesis SubPathway 59-67-6 CAS C00064 KEGG Compound CHEBI:16761 ChEBI P0A752 UniProt 1.0 962 PubChem-compound 388956 ChemSpider 5800 ChemSpider HMDB00855 HMDB Phosphate 5893 PubChem-compound 1.0 HMDB02111 HMDB C00080 KEGG Compound 6450-77-7 CAS 1.0 SMILES N[C@@H](CCC(O)=O)C(O)=O 1341-23-7 CAS CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound 1.0 C21H27N6O15P2 Nicotinic acid adenine dinucleotide 665.10095 Phosphate Transcriptional regulator nadR 1.0 1.0 C01185 KEGG Compound Phosphoribosyl pyrophosphate HMDB59646 HMDB HMDB59645 HMDB NAD synthetase, NH3-dependent CHEBI:15927 ChEBI Nicotinic acid adenine dinucleotide HMDB01488 HMDB 644102 PubChem-compound 6083 PubChem-compound 16741146 PubChem-compound SMILES N[C@@H](CCC(N)=O)C(O)=O NMN amidohydrolase PRPP BioCyc P18133 UniProt CHEBI:18050 ChEBI H2O Water 18.010565 SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O NadR DNA-binding transcriptional repressor and NMN adenylyltransferase NAD BioCyc HMDB00045 HMDB 1061 PubChem-compound SMILES OC1OC(COP([O-])([O-])=O)C(O)C1O HMDB00280 HMDB 1.0 NIACINE BioCyc DEAMIDO-NAD BioCyc 98-92-0 CAS 439924 PubChem-compound pncA pncB pncC nadD nadE nadR nadR NAD Water Hydrogen Ion Adenosine monophosphate beta- nicotinamide D- ribonucleotide Water Hydrogen Ion D-ribofuranose 5-phosphate Niacinamide Water Ammonium Nicotinic acid Water Adenosine triphosphate Phosphoribosyl pyrophosphate Phosphate Adenosine diphosphate Pyrophosphate nicotinate beta-D- ribonucleotide Water Ammonium nicotinate beta-D- ribonucleotide Adenosine triphosphate Hydrogen Ion Pyrophosphate Nicotinic acid adenine dinucleotide Water L-Glutamine Adenosine triphosphate Hydrogen Ion Adenosine monophosphate Pyrophosphate L-Glutamic acid NAD beta- nicotinamide D- ribonucleotide Water Phosphate Nicotinamide riboside Adenosine triphosphate Adenosine diphosphate Hydrogen Ion beta- nicotinamide D- ribonucleotide Adenosine triphosphate Hydrogen Ion Pyrophosphate NAD NADP Water Phosphate NAD NAD biosynthesis