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CHEBI:16015 ChEBI 388356 ChemSpider 6022 PubChem-compound 2.0 Phosphocarrier protein HPr C23H38N7O17P3S Acetyl-CoA 809.1258 937 ChemSpider 3-deoxy-D-manno-octulosonic-acid transferase HMDB00250 HMDB SubPathwayInteraction1561 SubPathway1561Reaction SubPathwayReaction HMDB01341 HMDB SubPathwayInteraction1562 SubPathwayReaction SubPathway1562Reaction Reaction3314 false Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate + Uridine triphosphate → Pyrophosphate + Uridine diphosphate-N-acetylglucosamine LEFT_TO_RIGHT C15H24N2O17P2 UDP-D-Galacto-1,4-furanose 566.055 1.0 2.7.7.23 false 2.7.7.23 Acetyl-CoA + Glucosamine-1P → Coenzyme A + Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate LEFT_TO_RIGHT 5.4.2.10 false 5.4.2.10 Glucosamine 6-phosphate ↔ Glucosamine-1P REVERSIBLE 6133 PubChem-compound 6131 PubChem-compound Glucosamine 6-phosphate P0AF98 UniProt Transport485 false phosphoethanolamine-Kdo2-lipid A (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Extracellular Space LEFT_TO_RIGHT 1.0 HMDB00148 HMDB P0ADV9 UniProt Lipopolysaccharide 1,2-glucosyltransferase ATP BioCyc Lipid A biosynthesis lauroyl acyltransferase CHEBI:16264 ChEBI PTS system mannose-specific EIIAB component HMDB00263 HMDB 53188-23-1 CAS Bifunctional protein glmU 1.0 4.0 P17115 UniProt 559142 ChemSpider 1.0 HMDB01109 HMDB ReactionCatalysis5256 ACTIVATION P0ADV1 UniProt P0AA04 UniProt 1.0 1.0 5746 ChemSpider HMDB01206 HMDB Lipopolysaccharide export system protein lptC P31554 UniProt ReactionCoupledTransportCatalysis198 ACTIVATION Phosphoethanolamine transferase eptB 5742 ChemSpider 439184 PubChem-compound UDP-galactopyranose mutase Lipopolysaccharide core biosynthesis protein rfaG Tetraacyldisaccharide 4'-kinase Lipopolysaccharide core heptosyltransferase rfaQ myristoyl-[acp] HMDB59597 HMDB 3.0 1.0 8140645 ChemSpider outer membrane lipopolysaccharide transport and assembly complex - LptD subunit outer membrane lipopolysaccharide transport and assembly complex - LptE subunit HMDB00124 HMDB C00105 KEGG Compound 6030 PubChem-compound 53477679 PubChem-compound 133-89-1 CAS Lipopolysaccharide core heptose(I) kinase rfaP Lipopolysaccharide heptosyltransferase 1 (3R)-3-hydroxymyristoyl-[acp] Acetyl-CoA Lipopolysaccharide 1,6-galactosyltransferase ADP-heptose--LPS heptosyltransferase 2 CHEBI:16241 ChEBI 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 3-deoxy-manno-octulosonate cytidylyltransferase Lipopolysaccharide 1,2-N-acetylglucosaminetransferase Lipopolysaccharide core heptose(II) kinase rfaY PPI BioCyc GLUCOSAMINE-1P BioCyc 440272 PubChem-compound P0ACV0 UniProt 63-37-6 CAS Reaction3565 false Fructose 6-phosphate + L-Glutamine → Glucosamine 6-phosphate + L-Glutamic acid LEFT_TO_RIGHT 138-08-9 CAS BiologicalState109 1.0 C6H14NO8P Glucosamine-1P 259.04572 1.0 HMDB01423 HMDB 2.0 1.0 Hydrogen Ion C5H10N2O3 L-Glutamine 146.06914 C00352 KEGG Compound Cytosol Adenosine triphosphate 3.6.3.- false 3.6.3.- lipid A-core + Adenosine triphosphate + Water → lipid A-core + Adenosine diphosphate + Hydrogen Ion + Phosphate LEFT_TO_RIGHT 2.0 1.0 C00009 KEGG Compound CHEBI:62000 ChEBI C6H12O6 D-Fructose 180.06339 C00008 KEGG Compound CHEBI:62001 ChEBI 3616-42-0 CAS 1.0 1.0 1.0 C00001 KEGG Compound UDP-2,3-diacylglucosamine hydrolase Arabinose 5-phosphate isomerase CTP BioCyc CHEBI:16064 ChEBI CHEBI:18361 ChEBI Lipopolysaccharide export system protein lptA CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound Phosphocarrier protein HPr 2-dehydro-3-deoxyphosphooctonate aldolase 5.4.99.9 false 5.4.99.9 UDP-α-D-galactose ↔ UDP-D-Galacto-1,4-furanose REVERSIBLE Phosphoglucosamine mutase HMDB01429 HMDB ReactionCatalysis3276 ACTIVATION ReactionCatalysis3277 ACTIVATION ReactionCatalysis3278 ACTIVATION 1.0 388775 ChemSpider CHEBI:17361 ChEBI C00010 KEGG Compound UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase FRUCTOSE-6P BioCyc ReactionCoupledTransportCatalysis150 ACTIVATION Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase CHEBI:17363 ChEBI C00013 KEGG Compound C6H14NO8P Glucosamine 6-phosphate 259.04572 Extracellular Space CHEBI:7125 ChEBI SMILES O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)C=O Protein gutQ D-GLUCOSAMINE-6-P BioCyc UDP-D-Galacto-1,4-furanose CHEBI:62004 ChEBI CHEBI:62002 ChEBI 562 TAXONOMY CHEBI:62003 ChEBI H Hydrogen Ion 1.007825 P27242 UniProt C00029 KEGG Compound glycolysis and pyruvate dehydrogenase SubPathway P27127 UniProt C01112 KEGG Compound 25244316 PubChem-compound L-Glutamine 56-65-5 CAS Glucosamine-1P Pentose Phosphate SubPathway C00025 KEGG Compound P27240 UniProt 62713 ChemSpider C00024 KEGG Compound ACET BioCyc Lipopolysaccharide 1,3-galactosyltransferase UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1.0 P27128 UniProt P27129 UniProt SMILES OC(COP([O-])([O-])=O)C(O)C(O)C(O)CC(=O)C([O-])=O SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO[C@]2([H])O[C@]([H])(CO)[C@@]([H])(OP([O-])([O-])=O)[C@]([H])(OC(=O)C[C@]([H])(O)CCCCCCCCCCC)[C@@]2([H])N=C([O-])C[C@]([H])(O)CCCCCCCCCCC)O[C@]([H])(OP(O)(O)=O)[C@]1([H])N=C([O-])C[C@]([H])(O)CCCCCCCCCCC SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO[C@]2([H])O[C@]([H])(CO[C@@]3(C[C@@]([H])(O[C@@]4(C[C@@]([H])(O)[C@@]([H])(O)[C@]([H])(O4)[C@]([H])(O)CO)C([O-])=O)[C@@]([H])(O)[C@]([H])(O3)[C@]([H])(O)CO)C([O-])=O)[C@@]([H])(OP([O-])([O-])=O)[C@]([H])(OC(=O)C[C@@]([H])(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@]2([H])N=C([O-])C[C@@]([H])(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@]([H])(OP(O)(O)=O)[C@]1([H])N=C([O-])C[C@]([H])(O)CCCCCCCCCCC SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO)O[C@@]([H])(OC[C@@]2([H])O[C@]([H])(OP(O)(O)=O)[C@]([H])(N=C([O-])C[C@]([H])(O)CCCCCCCCCCC)[C@@]([H])(OC(=O)C[C@]([H])(O)CCCCCCCCCCC)[C@]2([H])O)[C@]1([H])N=C([O-])C[C@]([H])(O)CCCCCCCCCCC SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O SMILES [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO SMILES CCCCCCCCCCC[C@@H](O)CC(=O)N[C@H]1[C@H](OC[C@H]2O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]2O)O[C@H](CO[C@@]2(C[C@@H](O)[C@@H](O)[C@H](O2)[C@H](O)CO)C([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H]1OC(=O)C[C@H](O)CCCCCCCCCCC SMILES [H][C@@](O)(CO)[C@@]1([H])O[C@@](C[C@@]([H])(O)[C@@]1([H])O)(OP(O)(=O)OC[C@@]1([H])O[C@@]([H])(N2C=CC(=N)N=C2O)[C@]([H])(O)[C@]1([H])O)C(O)=O SMILES OCC(O)C(O)C(O)C(O)CC(=O)C([O-])=O C00033 KEGG Compound 1.0 SMILES [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O[C@H]2O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO Lipid A export ATP-binding/permease protein msbA C02336 KEGG Compound SMILES CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)C(OCC2OC(OP([O-])([O-])=O)C(NC(=O)CC(O)CCCCCCCCCCC)C(OC(=O)CC(O)CCCCCCCCCCC)C2O)OC(COC2(CC(OC3(CC(O)C(O)C(O3)C(O)CO)C(C)=C)C(OC3OC(C(O)CO)C(O)C(OC4OC(C(O)CO)C(O)C(O)C4O)C3O)C(O2)C(O)CO)C([O-])=O)C1OP([O-])([O-])=O N-ACETYL-D-GLUCOSAMINE-1-P BioCyc 163687 ChemSpider 2.3.1.- false 2.3.1.- a-Kdo-(2->4)-a-Kdo-(2->6)-lipid IVA + dodecanoyl-[acp]  → (KDO)2-(lauroyl)-lipid IVA + a holo-[acyl-carrier protein] LEFT_TO_RIGHT Reaction3035 false CMP-3-deoxy-α-D-manno-octulosonate + alpha-Kdo-(2→6)-lipid IVA → Cytidine monophosphate + Hydrogen Ion + a-Kdo-(2->4)-a-Kdo-(2->6)-lipid IVA LEFT_TO_RIGHT Water 2.4.99.12 false 2.4.99.12 CMP-3-deoxy-α-D-manno-octulosonate + lipid IVA → Cytidine monophosphate + Hydrogen Ion + alpha-Kdo-(2→6)-lipid IVA LEFT_TO_RIGHT CHEBI:58603 ChEBI 2.7.7.38 false 2.7.7.38 3-deoxy-D-manno-octulosonate + Cytidine triphosphate → CMP-3-deoxy-α-D-manno-octulosonate + Pyrophosphate LEFT_TO_RIGHT lipopolysaccharide transport system 3.1.3.45 false 3.1.3.45 3-deoxy-D-manno-octulosonate 8-phosphate + Water → 3-deoxy-D-manno-octulosonate + Phosphate LEFT_TO_RIGHT P0A722 UniProt 2.5.1.55 false 2.5.1.55 D-Arabinose 5-phosphate + Phosphoenolpyruvic acid + Water → 3-deoxy-D-manno-octulosonate 8-phosphate + Phosphate LEFT_TO_RIGHT 5.3.1.13 false 5.3.1.13 D-Ribulose 5-phosphate → D-Arabinose 5-phosphate LEFT_TO_RIGHT SMILES NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O P0A725 UniProt C112H199N3O42P3 phosphoethanolamine-Kdo2-lipid A 2351.2773 SMILES [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](OP([O-])([O-])=O)[C@H](O[C@H]2O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO 2.-.-.- false 2.-.-.- ADP-L-glycero-beta-D-manno-heptose + heptosyl-Kdo2-lipid A → (heptosyl)2-Kdo2-lipid A + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 2.-.-.- false 2.-.-.- (KDO)2-lipid A + ADP-L-glycero-beta-D-manno-heptose → Adenosine diphosphate + Hydrogen Ion + heptosyl-Kdo2-lipid A LEFT_TO_RIGHT 2.3.1.- false 2.3.1.- myristoyl-[acp] + (KDO)2-(lauroyl)-lipid IVA → (KDO)2-lipid A + a holo-[acyl-carrier protein] LEFT_TO_RIGHT SMILES [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](OP([O-])([O-])=O)[C@H](O[C@H]2O[C@H]([C@@H](O)COC3O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](OP([O-])([O-])=O)[C@H](OC3O[C@H](COC4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO SMILES OC[C@H]1OC(OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO[C@]2([H])O[C@]([H])(CO[C@@]3(C[C@@]([H])(O[C@@]4(C[C@@]([H])(O)[C@@]([H])(O)[C@]([H])(O4)[C@]([H])(O)CO)C([O-])=O)[C@@]([H])(O[C@@]4([H])O[C@]([H])([C@@]([H])(O)CO)[C@@]([H])(OP([O-])([O-])=O)[C@]([H])(O[C@@]5([H])O[C@]([H])([C@@]([H])(O)COC6([H])O[C@]([H])([C@@]([H])(O)CO)[C@@]([H])(O)[C@]([H])(O)[C@]6([H])O)[C@@]([H])(OP([O-])([O-])=O)[C@]([H])(OC6([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]6([H])O)[C@]5([H])O)[C@]4([H])O)[C@]([H])(O3)[C@]([H])(O)CO)C([O-])=O)[C@@]([H])(OP([O-])([O-])=O)[C@]([H])(OC(=O)C[C@@]([H])(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@]2([H])N=C([O-])C[C@@]([H])(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@]([H])(OP(O)(O)=O)[C@]1([H])N=C([O-])C[C@]([H])(O)CCCCCCCCCCC SMILES [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](OP([O-])([O-])=O)[C@H](O[C@H]2O[C@H]([C@@H](O)COC3O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H](OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO P27300 UniProt SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO[C@]2([H])O[C@]([H])(CO[C@@]3(C[C@@]([H])(O[C@@]4(C[C@@]([H])(O)[C@@]([H])(O)[C@]([H])(O4)[C@]([H])(O)CO)C(O)O)[C@@]([H])(OC4([H])OC([H])([C@@]([H])(O)CO)[C@@]([H])(O[P+](O)(O)O)[C@]([H])(OC5([H])OC([H])([C@@]([H])(O)COC6([H])OC([H])([C@@]([H])(O)CO)[C@@]([H])(O)[C@]([H])(O)[C@]6([H])O)[C@@]([H])(O[P+](O)(O)O)[C@]([H])(OC6([H])O[C@]([H])(COC7([H])O[C@]([H])(CO)[C@]([H])(O)[C@]([H])(O)[C@@]7([H])O)[C@@]([H])(O)C([H])(OC7([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)C7([H])OC7([H])O[C@]([H])(COC8([H])OC([H])([C@@]([H])(O)CO)[C@@]([H])(O)[C@]([H])(O)[C@]8([H])O)[C@@]([H])(O)[C@]([H])(O)[C@@]7([H])O)[C@@]6([H])O)[C@]5([H])O)[C@]4([H])O)[C@]([H])(O3)[C@]([H])(O)CO)C(O)=O)[C@@]([H])(OP(O)(O)=O)[C@]([H])(OC(=O)C[C@@]([H])(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@]2([H])N=C(O)C[C@@]([H])(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@]([H])(OP(O)(O)=O)[C@]1([H])N=C(O)C[C@]([H])(O)CCCCCCCCCCC SMILES [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](OP([O-])([O-])=O)[C@H](O[C@H]2O[C@H]([C@@H](O)COC3O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](OP([O-])([O-])=O)[C@H](OC3O[C@H](COC4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@H](OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]3O)[C@@H]2O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO SMILES [H][C@@]1(O[C@@](C[C@@H](O)[C@H]1O)(O[C@@H]1C[C@@](OC[C@H]2O[C@@H](OC[C@H]3O[C@H](OP([O-])([O-])=O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]3O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2OP([O-])([O-])=O)(O[C@]([H])([C@H](O)CO)[C@@H]1O[C@H]1O[C@H]([C@@H](O)CO)[C@@H](OP([O-])([O-])=O)[C@H](O[C@H]2O[C@H]([C@@H](O)COC3O[C@H]([C@@H](O)CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](OP([O-])([O-])=O)[C@H](OC3O[C@H](COC4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@H](OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]3O)[C@@H]2O)[C@@H]1O)C([O-])=O)C([O-])=O)[C@H](O)CO C00043 KEGG Compound Mannose permease IID component Mannose permease IIC component 56-85-9 CAS HMDB00660 HMDB 3.5.1.- false 3.5.1.- UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + Water → Acetic acid + UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine LEFT_TO_RIGHT 58-97-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 2.3.1.129 false 2.3.1.129 (3R)-3-hydroxymyristoyl-[acp] + Uridine diphosphate-N-acetylglucosamine → UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + a holo-[acyl-carrier protein] LEFT_TO_RIGHT SMILES NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 PHOSPHO-ENOL-PYRUVATE BioCyc Lipid-A-disaccharide synthase HMDB00538 HMDB 2.7.1.130 false 2.7.1.130 Adenosine triphosphate + lipid A disaccharide → Adenosine diphosphate + Hydrogen Ion + lipid IVA LEFT_TO_RIGHT 2.4.1.182 false 2.4.1.182 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine → UDP + Hydrogen Ion + lipid A disaccharide LEFT_TO_RIGHT 3.6.1.54 false 3.6.1.54 UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine + Water → 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + Hydrogen Ion + Uridine 5'-monophosphate LEFT_TO_RIGHT SMILES OC(=O)C(=C)OP(O)(O)=O UTP BioCyc 2.3.1.191 false 2.3.1.191 (3R)-3-hydroxymyristoyl-[acp] + UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine → Hydrogen Ion + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine + a holo-[acyl-carrier protein] LEFT_TO_RIGHT SMILES [H][C@](O)(CO)[C@@]1([H])O[C@@]([H])(OP([O-])(=O)OP([O-])(=O)OC[C@@]2([H])O[C@@]([H])(N3C=NC4=C(N)N=CN=C34)[C@]([H])(O)[C@]2([H])O)[C@@]([H])(O)[C@@]([H])(O)[C@]1([H])O 5901 ChemSpider 5903 ChemSpider SMILES CC(O)=O C00055 KEGG Compound CHEBI:18251 ChEBI 7732-18-5 CAS CHEBI:18014 ChEBI 1.0 Lipopolysaccharide export system permease protein lptG 1.0 C00063 KEGG Compound Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 56-86-0 CAS 1.0 1.0 1.0 HMDB00641 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 445675 PubChem-compound C00064 KEGG Compound 1.0 6866-69-9 CAS SMILES CCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCCCCCC P24173 UniProt 2.4.1.56 false 2.4.1.56 ADP-L-glycero-beta-D-manno-heptose + galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate → lipid A-core + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT 2.4.1.58 false 2.4.1.58 Uridine diphosphate glucose + galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate → UDP + Hydrogen Ion + galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate LEFT_TO_RIGHT Lipopolysaccharide export system permease protein lptF 65-47-4 CAS 2.4.1.44 false 2.4.1.44 Uridine diphosphate glucose + galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate → UDP + Hydrogen Ion + galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate LEFT_TO_RIGHT 2.4.1.- false 2.4.1.- UDP-α-D-galactose + glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate → UDP + Hydrogen Ion + galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate LEFT_TO_RIGHT C00074 KEGG Compound 2.7.1.- false 2.7.1.- Adenosine triphosphate + glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate → Adenosine diphosphate + Hydrogen Ion + glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate LEFT_TO_RIGHT 2.-.-.- false 2.-.-.- ADP-L-glycero-beta-D-manno-heptose + glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate → Adenosine diphosphate + Hydrogen Ion + glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate LEFT_TO_RIGHT 2.7.1.- false 2.7.1.- Adenosine triphosphate + glucosyl-(heptosyl)2-Kdo2-lipid A → Adenosine diphosphate + Hydrogen Ion + glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate LEFT_TO_RIGHT Lipopolysaccharide export system ATP-binding protein lptB 3-deoxy-D-manno-octulosonic-acid transferase 2.4.-.- false 2.4.-.- (heptosyl)2-Kdo2-lipid A + Uridine diphosphate glucose → UDP + Hydrogen Ion + glucosyl-(heptosyl)2-Kdo2-lipid A LEFT_TO_RIGHT 1.0 962 PubChem-compound 5800 ChemSpider RIBULOSE-5P BioCyc C00199 KEGG Compound Lipopolysaccharide 1,2-glucosyltransferase C00075 KEGG Compound 4.0 Phosphate CMP BioCyc 1.0 Bifunctional protein glmU C00080 KEGG Compound CHEBI:57957 ChEBI C00085 KEGG Compound 9965052 PubChem-compound Lipid A biosynthesis lauroyl acyltransferase 8490 PubChem-compound 1.0 SMILES N[C@@H](CCC(O)=O)C(O)=O 5808 ChemSpider CHEBI:44897 ChEBI 14265-44-2 CAS 6176 PubChem-compound C5H11O8P D-Ribulose 5-phosphate 230.01915 58-64-0 CAS 1.0 Lipopolysaccharide export system protein lptC dodecanoyl-[acp]  Tetraacyldisaccharide 4'-kinase 1.0 UDP-galactopyranose mutase HMDB00618 HMDB P37661 UniProt 644102 PubChem-compound 444493 PubChem-compound 5941 ChemSpider D-Ribulose 5-phosphate 188324 PubChem-compound SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O 1.0 ACETYL-COA BioCyc CHEBI:18050 ChEBI H2O Water 18.010565 1.0 SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O TransportCatalysis417 ACTIVATION HMDB11734 HMDB UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O P37692 UniProt phosphoethanolamine-Kdo2-lipid A SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO)O[C@]([H])(OP(O)(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=CC([O-])=NC3=O)[C@]([H])(O)[C@]2([H])O)[C@]1([H])N=C(C)[O-] 1.0 UMP BioCyc SMILES CCCCCCCCCCCC(O)CC(=O)NC1C(OP([O-])([O-])=O)OC(CO)C(O)C1OC(=O)CC(O)CCCCCCCCCCC SMILES [H]C(O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO)OC([H])(OP(O)(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=CC(O)=NC3=O)[C@]([H])(O)[C@]2([H])O)[C@]1([H])N=C(O)CC([H])(O)CCCCCCCCCCC SMILES CCCCCCCCCCCC(O)CC(=O)NC1C(OP([O-])([O-])=O)OC(COC2OC(COC3(CC(OC4(CC(O)C(O)C(O4)C(O)CO)C([O-])=O)C(O)C(O3)C(O)CO)C([O-])=O)C(OP([O-])([O-])=O)C(OC(=O)CC(O)CCCCCCCCCCC)C2NC(=O)CC(O)CCCCCCCCCCC)C(O)C1OC(=O)CC(O)CCCCCCCCCCC SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@]1([H])[C@@]([H])(N)[C@@]([H])(OP(O)(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=CC([O-])=NC3=O)[C@]([H])(O)[C@]2([H])O)O[C@]([H])(CO)[C@@]1([H])O SMILES [H][C@@](O)(CCCCCCCCCCC)CC(=O)O[C@@]1([H])[C@]([H])(O)[C@@]([H])(CO[C@]2([H])O[C@]([H])(CO[C@@]3(C[C@@]([H])(O[C@@]4(C[C@@]([H])(O)[C@@]([H])(O)[C@]([H])(O4)[C@]([H])(O)CO)C(O)=O)[C@@]([H])(O)[C@]([H])(O3)[C@]([H])(O)CO)C(O)=O)[C@@]([H])(OP(O)(O)=O)[C@]([H])(OC(=O)C[C@]([H])(O)CCCCCCCCCCC)[C@@]2([H])N=C(O)C[C@@]([H])(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@]([H])(OP(O)(O)=O)[C@]1([H])N=C(O)C[C@]([H])(O)CCCCCCCCCCC D-arabinose 5-phosphate isomerase SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1OP(O)(O)=O P0A9V1 UniProt 3-deoxy-D-manno-octulosonate 8-phosphate synthase D-arabinose 5-phosphate isomerase 2 980 ChemSpider lipid A disaccharide synthase P0A715 UniProt C27H54NO8P PE(12:0/10:0) 551.3587 Adenosine diphosphate Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1.0 PE(12:0/10:0) UDP-α-D-galactose galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate 30572 ChemSpider galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate CPD-535 BioCyc C2H4O2 Acetic acid 60.02113 P04951 UniProt glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate 1.0 lipid A-core 1.0 Cytidine triphosphate 64-19-7 CAS P24205 UniProt SMILES O Lipopolysaccharide export system protein lptA 2.7.-.- false 2.7.-.- PE(12:0/10:0) + a-Kdo-(2->4)-a-Kdo-(2->6)-lipid IVA → 1,2-Diacyl-sn-glycerol (didodecanoyl, n-C12:0) + phosphoethanolamine-Kdo2-lipid A LEFT_TO_RIGHT 1.0 CHEBI:9803 ChEBI Pyrophosphate lipid IVA (KDO)2-lipid A 3-deoxy-D-manno-octulosonate 8-phosphate 1.0 3-deoxy-D-manno-octulosonate P37747 UniProt CMP-3-deoxy-α-D-manno-octulosonate 439709 PubChem-compound UDP lipid A disaccharide C31H51N3O19P2 UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine 831.2603 CHEBI:58466 ChEBI C29H50N3O18P2 UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine 790.2565 CHEBI:58223 ChEBI C43H77N3O20P2 UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine 1017.4576 C84H148N2O37P2 a-Kdo-(2->4)-a-Kdo-(2->6)-lipid IVA 1838.9269 C34H64NO12P 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate 709.4177 1005 PubChem-compound alpha-Kdo-(2→6)-lipid IVA 5961 PubChem-compound heptosyl-Kdo2-lipid A 1.0 C96H176N2O38P2 (KDO)2-(lauroyl)-lipid IVA 2027.1376 (heptosyl)2-Kdo2-lipid A P45395 UniProt glucosyl-(heptosyl)2-Kdo2-lipid A D-fructose-6-phosphate aminotransferase Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase 1.0 2-dehydro-3-deoxyphosphooctonate aldolase 643-13-0 CAS 528-04-1 CAS 1.0 CHEBI:61506 ChEBI P0ACC7 UniProt 6816 PubChem-compound CHEBI:61507 ChEBI UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 4.0 CHEBI:61502 ChEBI lipopolysaccharide biosynthesis ADP BioCyc C9H14N2O12P2 UDP 404.0022 C68H127N2O20P lipid A disaccharide 1322.872 1.0 C68H126N2O23P2 lipid IVA 1400.8226 C110H196N2O39P2 (KDO)2-lipid A 2231.2922 C8H12O11P 3-deoxy-D-manno-octulosonate 8-phosphate 315.01337 C8H13O8 3-deoxy-D-manno-octulosonate 237.06158 P60752 UniProt C17H26N3O15P CMP-3-deoxy-α-D-manno-octulosonate 543.11017 C76H137N2O30P2 alpha-Kdo-(2→6)-lipid IVA 1619.8759 C117H208N2O45P2 heptosyl-Kdo2-lipid A 2423.3557 1.0 C126H225N2O49P2 (heptosyl)2-Kdo2-lipid A 2612.4678 C130H230N2O56P2 glucosyl-(heptosyl)2-Kdo2-lipid A 2777.472 1038 PubChem-compound C04256 KEGG Compound 1,2-Diacyl-sn-glycerol (didodecanoyl, n-C12:0) GO:0005829 GENE ONTOLOGY CHEBI:61999 ChEBI fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase CHEBI:61997 ChEBI CHEBI:61998 ChEBI Protein gutQ 1.0 393240 ChemSpider C130H229N2O59P3 glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate 2855.4238 ADP-L-glycero-beta-D-manno-heptose C137H241N2O65P3 glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate 3047.487 C137H240N2O68P4 glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate 3125.439 Fructose 6-phosphate 1.0 C15H22N2O17P2 UDP-α-D-galactose 564.04047 PW000831 PathWhiz C143H250N2O73P4 galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate 3287.4917 C149H260N2O78P4 galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate 3449.5444 C155H270N2O83P4 galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate 3611.5974 CHEBI:15713 ChEBI 1.0 C162H296N2O89P4 lipid A-core 3817.765 O4P Phosphate 94.95342 Acetic acid 4.0 CHEBI:58368 ChEBI GO:0070258 GENE ONTOLOGY Lipopolysaccharide 1,3-galactosyltransferase CHEBI:15946 ChEBI CHEBI:61524 ChEBI SMP00851 SMPDB 1.0 mannose PTS permease PW000785 PathWhiz D-Fructose C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc P69797 UniProt C9H15N2O15P3 Uridine triphosphate 483.96854 L-Glutamic acid Mannose permease IID component SMILES [O-]P([O-])([O-])=O 1.0 C6H13O9P Fructose 6-phosphate 260.02972 Hydrogen Ion C17H27N3O17P2 Uridine diphosphate-N-acetylglucosamine 607.08154 1.0 C9H13N2O9P Uridine 5'-monophosphate 324.03586 phosphoethanolamine-Kdo2-lipid A PW000893 PathWhiz a holo-[acyl-carrier protein] SMP00912 SMPDB lipid A-core CHEBI:58540 ChEBI Inner Membrane N-Acetyl-glucosamine 1-phosphate Lipopolysaccharide export system permease protein lptG ReactionCatalysis2987 ACTIVATION ReactionCatalysis2986 ACTIVATION C8H16NO9P N-Acetyl-glucosamine 1-phosphate 301.05627 ReactionCatalysis2989 ACTIVATION ReactionCatalysis2988 ACTIVATION GLN BioCyc GLT BioCyc SMILES [H][C@@](COC(=O)CCCCCCCCCCC)(COP(O)(=O)OCCN)OC(=O)CCCCCCCCC 69507 PubChem-compound Mannose permease IIC component 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate (KDO)2-(lauroyl)-lipid IVA 1.0 UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine SMP00807 SMPDB UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine a-Kdo-(2->4)-a-Kdo-(2->6)-lipid IVA a holo-[acyl-carrier protein] P0ADC1 UniProt ReactionCatalysis2996 ACTIVATION Uridine diphosphate-N-acetylglucosamine ReactionCatalysis2995 ACTIVATION O7P2 Pyrophosphate 173.91193 Uridine 5'-monophosphate ReactionCatalysis2998 ACTIVATION ReactionCatalysis2997 ACTIVATION Uridine diphosphate glucose Fructose 6-phosphate ReactionCatalysis2999 ACTIVATION 5957 PubChem-compound C9H16N3O14P3 Cytidine triphosphate 482.9845 1.0 ReactionCatalysis2990 ACTIVATION 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase ReactionCatalysis2992 ACTIVATION Uridine triphosphate ReactionCatalysis2991 ACTIVATION SMILES CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)C(OCC2OC(OP([O-])([O-])=O)C(NC(=O)CC(O)CCCCCCCCCCC)C(OC(=O)CC(O)CCCCCCCCCCC)C2O)OC(COC2(CC(OC3(CC(O)C(O)C(O3)C(CO)OP([O-])(=O)OCC[N+])C([O-])=O)C(O)C(O2)C(O)CO)C([O-])=O)C1OP([O-])([O-])=O ReactionCatalysis2994 ACTIVATION 8.0 ReactionCatalysis2993 ACTIVATION Lipopolysaccharide core biosynthesis protein rfaG Lipopolysaccharide core heptosyltransferase rfaQ CHEBI:15873 ChEBI Phosphoethanolamine transferase eptB P25741 UniProt P25740 UniProt SMILES OCC(=O)[C@H](O)[C@H](O)COP(O)(O)=O Cytidine monophosphate Adenosine diphosphate C3H5O6P Phosphoenolpyruvic acid 167.98238 CHEBI:58439 ChEBI C10H15N5O10P2 Adenosine diphosphate 427.02942 C06251 KEGG Compound P0ADC6 UniProt GO:0005615 GENE ONTOLOGY 4151-19-3 CAS P25742 UniProt Lipopolysaccharide export system ATP-binding protein lptB Phosphoenolpyruvic acid C9H14N3O8P Cytidine monophosphate 323.05185 Lipopolysaccharide export system permease protein lptF (3R)-3-hydroxymyristoyl-[acp] 1.0 1.0 Lipopolysaccharide heptosyltransferase 1 Lipopolysaccharide core heptose(I) kinase rfaP Adenosine triphosphate ADP-heptose--LPS heptosyltransferase 2 Lipopolysaccharide 1,6-galactosyltransferase Lipopolysaccharide 1,2-N-acetylglucosaminetransferase CPD-8587 BioCyc 3-deoxy-manno-octulosonate cytidylyltransferase HMDB00095 HMDB Lipopolysaccharide core heptose(II) kinase rfaY SMILES N[C@H]1[C@@H](O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O C06025 KEGG Compound CHEBI:1146900 ChEBI CHEBI:28645 ChEBI myristoyl-[acp] 46173153 PubChem-compound CHEBI:60364 ChEBI 14000-31-8 CAS CHEBI:60365 ChEBI Phosphate P10441 UniProt CO-A BioCyc 1.0 72-89-9 CAS C06026 KEGG Compound C06398 KEGG Compound Lipid A export ATP-binding/permease protein msbA Coenzyme A 1.0 C21H36N7O16P3S Coenzyme A 767.11523 dodecanoyl-[acp]  P0ABZ4 UniProt P31120 UniProt Water CHEBI:15422 ChEBI Arabinose 5-phosphate isomerase UDP-2,3-diacylglucosamine hydrolase 6557 ChemSpider 13137-52-5 CAS 1.0 outer membrane lipopolysaccharide transport and assembly complex - LptD subunit Phosphoglucosamine mutase SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N P43341 UniProt outer membrane lipopolysaccharide transport and assembly complex - LptE subunit ReactionCatalysis3008 ACTIVATION ReactionCatalysis3009 ACTIVATION ReactionCatalysis3006 ACTIVATION ReactionCatalysis3007 ACTIVATION ReactionCatalysis3000 ACTIVATION ReactionCatalysis3001 ACTIVATION ReactionCatalysis3004 ACTIVATION 439217 PubChem-compound ReactionCatalysis3005 ACTIVATION ReactionCatalysis3002 ACTIVATION ReactionCatalysis3003 ACTIVATION C5H9NO4 L-Glutamic acid 147.05316 CHEBI:61494 ChEBI 33032 PubChem-compound 3.0 1.0 HMDB00082 HMDB UDP-N-ACETYL-D-GLUCOSAMINE BioCyc CHEBI:16761 ChEBI 1.0 ReactionCatalysis3010 ACTIVATION ReactionCoupledTransport164 false D-Fructose + HPr - phosphorylated → Fructose 6-phosphate + HPr LEFT_TO_RIGHT CHEBI:15366 ChEBI 389248 ChemSpider C17H25N5O16P2 ADP-L-glycero-beta-D-manno-heptose 617.07825 1.0 392413 ChemSpider HMDB00290 HMDB UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase CHEBI:16695 ChEBI 1.0 HMDB02111 HMDB 1.0 171 ChemSpider 1.0 CHEBI:15377 ChEBI CHEBI:17677 ChEBI CHEBI:15378 ChEBI SMILES [H+] SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O ARABINOSE-5P BioCyc C27H52O5 1,2-Diacyl-sn-glycerol (didodecanoyl, n-C12:0) 456.38147 C5H11O8P D-Arabinose 5-phosphate 230.01915 CHEBI:71573 ChEBI 1.0 P21645 UniProt 1.0 ReactionCatalysis3554 ACTIVATION P0AC75 UniProt ReactionCatalysis5851 ACTIVATION 1.0 HMDB01367 HMDB 2.0 Lipid-A-disaccharide synthase SMILES N[C@@H](CCC(N)=O)C(O)=O 1.0 SMILES N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OP(O)(O)=O D-Arabinose 5-phosphate 1.0 P17169 UniProt SMILES [H][C@@](O)(CO)[C@]1([H])O[C@]([H])(OP(O)(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=CC(O)=NC3=O)[C@]([H])(O)[C@]2([H])O)[C@]([H])(O)[C@@]1([H])O HMDB00288 HMDB 1061 PubChem-compound 63-39-8 CAS 1.0 Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase PTS system mannose-specific EIIAB component CHEBI:15351 ChEBI HMDB00042 HMDB 1.0 SMILES OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O HMDB01254 HMDB HMDB00285 HMDB 176 PubChem-compound HMDB00286 HMDB P69801 UniProt phosphoethanolamine-Kdo2-lipid A P69805 UniProt 85-61-0 CAS