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388358 ChemSpider 388356 ChemSpider 6022 PubChem-compound 1.0 Phosphocarrier protein HPr GDP-mannose 4,6-dehydratase 937 ChemSpider Galactose-1-phosphate uridylyltransferase 16500 PubChem-compound HMDB00250 HMDB HMDB01341 HMDB 1.0 Reaction3311 false Chitin + Water → Chitin + N-Acetyl-D-glucosamine LEFT_TO_RIGHT Glucose-specific phosphotransferase enzyme IIA component 3.2.1.14 false 3.2.1.14 Chitin + Water → Chitin + Chitobiose LEFT_TO_RIGHT 1.0 1.0 1.0 C00446 KEGG Compound alpha-D-glucose-1-phosphate 1.0 3.2.1.52 false 3.2.1.52 Chitobiose + Water → 2 N-Acetyl-D-glucosamine LEFT_TO_RIGHT ATP BioCyc PTS system mannose-specific EIIAB component Probable bifunctional chitinase/lysozyme Glucose-1-phosphate adenylyltransferase C8H16NO9P N-Acetyl-D-Glucosamine 6-Phosphate 301.05627 H4N Ammonium 18.034374 C15H26N2O12 Chitobiose 426.14856 PTS system glucose-specific EIICB component C14830 KEGG Compound 559142 ChemSpider Mannose-6-phosphate isomerase 2.7.1.59 false 2.7.1.59 Adenosine triphosphate + N-Acetyl-D-glucosamine → Adenosine diphosphate + Hydrogen Ion + N-Acetyl-D-Glucosamine 6-Phosphate LEFT_TO_RIGHT 3.5.99.6 false 3.5.99.6 Glucosamine 6-phosphate + Water → Ammonium + β-D-fructofuranose 6-phosphate LEFT_TO_RIGHT 3.5.1.25 false 3.5.1.25 N-Acetyl-D-Glucosamine 6-Phosphate + Water → Acetic acid + Glucosamine 6-phosphate LEFT_TO_RIGHT 4.2.1.126 false 4.2.1.126 MurNAc-6-P + Water → D-Lactic acid + N-Acetylglucosamine 6-phosphate LEFT_TO_RIGHT C6H13O9P alpha-D-glucose-1-phosphate 260.02972 P0AA04 UniProt SMILES [Na+].[Na+].[H][C@]1(COP([O-])(=O)OP(O)(=O)OC2([H])O[C@]([H])(CO)[C@]([H])(O)[C@]([H])(O)[C@@]2([H])O)OC([H])(N2C=CC([O-])=NC2=O)[C@]([H])(O)[C@]1([H])O ReactionCatalysis5142 ACTIVATION D-LACTATE BioCyc 5742 ChemSpider 1.0 Probable bifunctional chitinase/lysozyme N-acetylglucosamine-6-phosphate deacetylase CHEBI:16474 ChEBI ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc HMDB59597 HMDB 17216232 ChemSpider Glucosamine 6-phosphate MurNAc-6-P 1.0 53477679 PubChem-compound α-D-glucose 6-phosphate 133-89-1 CAS 439174 PubChem-compound C00461 KEGG Compound SMILES C[C@@H](O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C([O-])=O 10326-41-7 CAS 1010 ChemSpider N-acetylmuramic acid PTS permease C01674 KEGG Compound P00946 UniProt HMDB41827 HMDB PPI BioCyc P76535 UniProt SMILES C[C@@H](O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@@H](O)[C@@H]1NC(C)=O)C([O-])=O BiologicalState109 C15H22N2Na2O17P2 UDP-galactose 610.0189 BiologicalState108 CHEBI:17029 ChEBI 1.0 C6H13O9P Galactose 1-phosphate 260.02972 C16H25N5O15P2 ADP-glucose 589.0822 1.0 C10H16N5O14P3 Guanosine triphosphate 522.99066 HMDB00215 HMDB 388319 ChemSpider Hydrogen Ion HMDB00217 HMDB C8H16NO9P N-Acetylglucosamine 6-phosphate 301.05627 C00352 KEGG Compound Cytosol Glucosamine-6-phosphate deaminase 2.0 SubPathwayInteraction1765 SubPathway1765Reaction SubPathwayReaction C00357 KEGG Compound 1.0 glucose PTS permease P0A6V1 UniProt Reaction3354 false UDP-galactose + alpha-D-glucose-1-phosphate → Galactose 1-phosphate + Uridine diphosphate glucose LEFT_TO_RIGHT Chitin ReactionCoupledTransport114 false HPr - phosphorylated + alpha-D-mannose → HPr + α-D-mannose 6-phosphate LEFT_TO_RIGHT 2.0 ReactionCatalysis3268 ACTIVATION ReactionCatalysis3269 ACTIVATION ReactionCatalysis3267 ACTIVATION HMDB01311 HMDB HMDB00221 HMDB 3616-42-0 CAS C00008 KEGG Compound C00006 KEGG Compound ReactionCoupledTransportCatalysis148 ACTIVATION ReactionCatalysis3272 ACTIVATION Hydrogen Ion CHEBI:18009 ChEBI C00001 KEGG Compound C11H18NO8 MurNAc 292.1038 CHEBI:18361 ChEBI C00005 KEGG Compound C00002 KEGG Compound Phosphocarrier protein HPr N-acetylglucosamine-6-phosphate deacetylase C6H12O6 Alpha-D-Glucose 180.06339 ReactionCatalysis3275 ACTIVATION ReactionCatalysis3273 ACTIVATION ReactionCatalysis3274 ACTIVATION 2.7.7.27 false 2.7.7.27 Adenosine triphosphate + alpha-D-glucose-1-phosphate → ADP-glucose + Pyrophosphate LEFT_TO_RIGHT 5.4.2.2 false 5.4.2.2 α-D-glucose 6-phosphate → α-D-glucose 1-phosphate LEFT_TO_RIGHT C11H17NO11P MurNAc-6-P 370.05557 Chitobiose C01342 KEGG Compound C00256 KEGG Compound C00498 KEGG Compound SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)C(=O)N1 C6H14NO8P Glucosamine 6-phosphate 259.04572 C00013 KEGG Compound Glucosamine-6-phosphate deaminase C00140 KEGG Compound NAD(P) BioCyc GDP-L-fucose synthase D-GLUCOSAMINE-6-P BioCyc ReactionCoupledTransport133 false Alpha-D-Glucose + HPr - phosphorylated → HPr + α-D-glucose 6-phosphate LEFT_TO_RIGHT 1.0 562 TAXONOMY H Hydrogen Ion 1.007825 N-acetylglucosamine-6-phosphate deacetylase C00029 KEGG Compound ReactionCoupledTransportCatalysis167 ACTIVATION glucose-1-phosphate adenylyltransferase 56-65-5 CAS 1.0 ReactionCoupledTransportCatalysis161 ACTIVATION Galactose 1-phosphate ReactionCoupledTransportCatalysis160 ACTIVATION C00267 KEGG Compound Guanosine triphosphate Reaction3363 false GDP-4-dehydro-6-deoxy-α-D-mannose + Hydrogen Ion + NADPH → GDP-β-L-fucose + NADP LEFT_TO_RIGHT ACET BioCyc 2.7.1.69 false 2.7.1.69 HPr - phosphorylated + N-Acetyl-D-glucosamine → HPr + N-Acetyl-D-Glucosamine 6-Phosphate LEFT_TO_RIGHT Reaction3362 false Guanosine diphosphate mannose → GDP-4-dehydro-6-deoxy-α-D-mannose + Water LEFT_TO_RIGHT Reaction3361 false Guanosine triphosphate + Hydrogen Ion + α-D-mannose 1-phosphate → Guanosine diphosphate mannose + Pyrophosphate LEFT_TO_RIGHT 5.4.2.8 false 5.4.2.8 α-D-mannose 6-phosphate ↔ α-D-mannose 1-phosphate REVERSIBLE 2.7.1.- false 2.7.1.- HPr - phosphorylated + MurNAc → HPr + MurNAc-6-P LEFT_TO_RIGHT 1.0 4.0 1.0 1.0 15642 ChemSpider 577-76-4 CAS C00033 KEGG Compound 4.0 2.0 Water 123912 PubChem-compound PTS system glucose-specific EIICB component SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 1.0 C00044 KEGG Compound P0AF18 UniProt 2140-58-1 CAS Mannose permease IID component Mannose permease IIC component SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 1.0 HMDB00538 HMDB 389821 ChemSpider 399508 ChemSpider SMILES CC(O)=O 7732-18-5 CAS C28H49N3O16 Chitin 683.3113 110443 ChemSpider Phosphomannomutase Mannose-1-phosphate guanylyltransferase ADP-glucose 53477726 PubChem-compound 492-62-6 CAS 14-N-ACETYL-BETA-D-GLUCOSAMINYLN1 BioCyc C10H16N5O13P3 Adenosine triphosphate 506.99576 HMDB00645 HMDB GDP-mannose 4,6-dehydratase 1.0 P24174 UniProt P24175 UniProt CHEBI:7212 ChEBI SMILES C[C@@H](O)C(O)=O N-Acetyl-D-Glucosamine 6-Phosphate P0A759 UniProt HMDB02817 HMDB 1.0 962 PubChem-compound N-Acetyl-D-Glucosamine 6-Phosphate N-Acetyl-D-glucosamine PW000941 PathWhiz SMILES OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O N-Acetylglucosamine 6-phosphate 5800 ChemSpider SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O P75959 UniProt C00080 KEGG Compound 1746-32-3 CAS CHEBI:42111 ChEBI α-D-glucose 1-phosphate SMILES OCC1OC(O)C(O)C(O)C1O SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O 58-64-0 CAS 22833609 PubChem-compound GTP BioCyc 71358 ChemSpider SMILES C[C@@H]1OC(OP(O)(=O)OP(O)(=O)OCC2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@H](O)C1=O P75949 UniProt C00096 KEGG Compound 2255-14-3 CAS Acetic acid 644102 PubChem-compound SMILES [H][C@]1(COP([O-])(=O)OP(O)(=O)O[C@@]2([H])O[C@]([H])(C)C(=O)[C@]([H])(O)[C@]2([H])O)O[C@@]([H])(N2C=NC3=C2NC(=N)N=C3[O-])[C@]([H])(O)[C@]1([H])O Glucose-specific phosphotransferase enzyme IIA component SMILES CC1OC(OP([O-])(=O)OP([O-])(=O)OCC2OC(C(O)C2O)N2C=NC3=C2NC(N)=NC3=O)C(O)C(O)C1O Phosphoglucomutase-1 22833512 PubChem-compound 1.0 18396 PubChem-compound H2O Water 18.010565 α-D-mannose 6-phosphate Ammonium 6.0 1.0 SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O N-acetylmuramic acid 6-phosphate etherase CHEBI:57273 ChEBI 1.0 102029-88-9 CAS 1.0 CHEBI:57634 ChEBI MurNAc CHEBI:58601 ChEBI CHEBI:58721 ChEBI GDP-4-DEHYDRO-6-L-DEOXYGALACTOSE BioCyc ReactionCatalysis2924 ACTIVATION 17215925 ChemSpider C2H4O2 Acetic acid 60.02113 C16H21N5O15P2 GDP-4-dehydro-6-deoxy-α-D-mannose 585.05206 α-D-mannose 1-phosphate C16H23N5O15P2 GDP-β-L-fucose 587.0677 64-19-7 CAS SMILES O 21252321 PubChem-compound Pyrophosphate N-acetylmuramic acid 6-phosphate etherase SMP00958 SMPDB Reaction5171 false Guanosine diphosphate mannose → GDP-4-Dehydro-6-L-deoxygalactose LEFT_TO_RIGHT GALACTOSE-1P BioCyc CHEBI:58225 ChEBI C3H6O3 D-Lactic acid 90.03169 ADP BioCyc P32055 UniProt ALPHA-D-GALACTOSYL-13-BETA-D-GALACTOS BioCyc N-ACETYL-D-GLUCOSAMINE-6-P BioCyc 53-59-8 CAS CHEBI:15820 ChEBI 1038 PubChem-compound Alpha-D-Glucose GO:0005829 GENE ONTOLOGY 1.0 1.0 CHITOBIOSE BioCyc 55423 ChemSpider N-Acetyl-D-glucosamine Pyrophosphate NADPH 6830 PubChem-compound GO:0070258 GENE ONTOLOGY NADP C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 C8H15NO6 N-Acetyl-D-glucosamine 221.08994 1.0 mannose PTS permease alpha-D-mannose α-D-mannose 6-phosphate NADPH BioCyc HMDB06557 HMDB 218 ChemSpider SMP00906 SMPDB 1.0 C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc P69797 UniProt Mannose permease IID component galactose-1-phosphate uridylyltransferase Amino sugar and nucleotide sugar metabolism II 1398-61-4 CAS 1.0 GDP-MANNOSE BioCyc PTS system N-acetylglucosamine-specific EIICBA component β-D-fructofuranose 6-phosphate Galactose-1-phosphate uridylyltransferase 2.0 P69783 UniProt 1.0 Inner Membrane SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O P69786 UniProt SMILES CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O 1.0 SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 1.0 PW000887 PathWhiz 1.0 Mannose permease IIC component 53-57-6 CAS 1.0 P77272 UniProt C6H11O9P β-D-fructofuranose 6-phosphate 258.01517 P09148 UniProt CHEBI:16955 ChEBI CHEBI:28938 ChEBI Mannose-6-phosphate isomerase C6H11O9P α-D-glucose 6-phosphate 258.01517 α-D-glucose 1-phosphate alpha-D-glucose-1-phosphate O7P2 Pyrophosphate 173.91193 Uridine diphosphate glucose 17372 ChemSpider 5957 PubChem-compound CHEBI:15751 ChEBI CHEBI:15873 ChEBI C6H11O9P α-D-mannose 6-phosphate 258.01517 CHEBI:15996 ChEBI 5.3.1.8 false 5.3.1.8 α-D-mannose 6-phosphate ↔ β-D-fructofuranose 6-phosphate REVERSIBLE C6H12O6 alpha-D-mannose 180.06339 CHEBI:57964 ChEBI GDP-β-L-fucose GDP-4-dehydro-6-deoxy-α-D-mannose P13656 UniProt 440996 PubChem-compound α-D-mannose 1-phosphate 1.0 Adenosine triphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 P36871 UniProt CHEBI:17925 ChEBI Beta-hexosaminidase P09323 UniProt N-acetyl-D-glucosamine kinase HMDB03362 HMDB CHEBI:58409 ChEBI HMDB01062 HMDB SMILES N[C@H]1[C@@H](O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O 2.0 14000-31-8 CAS PTS system N-acetylmuramic acid-specific EIIBC component 5675 ChemSpider N-acetyl-D-glucosamine kinase Phosphoglucomutase-1 N-acetylglucosamine PTS permease Adenosine diphosphate 14798-03-9 CAS α-D-glucose 6-phosphate CHEBI:15784 ChEBI 1.0 HMDB03345 HMDB CHEBI:15422 ChEBI β-D-fructofuranose 6-phosphate HMDB01163 HMDB 1.0 Beta-hexosaminidase 439217 PubChem-compound 439219 PubChem-compound Water SMILES [NH4+] CHEBI:17973 ChEBI UDP-galactose N-acetylmuramic acid 6-phosphate etherase starch and sucrose metabolism SubPathway GDP-L-fucose synthase CHEBI:28729 ChEBI SMILES CC(=O)N[C@H]1C(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O SMILES CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(O)=O)[C@@H]1O CHEBI:16761 ChEBI CHEBI:506227 ChEBI C16H23N5O15P2 GDP-4-Dehydro-6-L-deoxygalactose 587.0666 PTS system N-acetylglucosamine-specific EIICBA component GDP-4-Dehydro-6-L-deoxygalactose 1.0 CHEBI:15366 ChEBI C16H25N5O16P2 Guanosine diphosphate mannose 605.07715 Glucose-1-phosphate adenylyltransferase PTS system N-acetylmuramic acid-specific EIIBC component SMILES CC(=O)NC1[C@H](O)OC(CO)[C@@H](COC[C@@H]2OC(CO)[C@@H](COC[C@@H]3OC(CO)[C@@H](O)[C@H](O)C3NC(C)=O)[C@H](O)C2NC(C)=O)[C@@H]1O HMDB02111 HMDB 1.0 171 ChemSpider D-Lactic acid CHEBI:15377 ChEBI glucosamine-6-phosphate deaminase CHEBI:15378 ChEBI SMILES [H+] 6569 ChemSpider HMDB01391 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound HMDB01273 HMDB ReactionCatalysis3317 ACTIVATION 3123-67-9 CAS 1.0 ReactionCatalysis3318 ACTIVATION 79025 PubChem-compound 61503 PubChem-compound CHEBI:60332 ChEBI P0AC88 UniProt SMILES NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@H]3O)C2=NC=N1 16741146 PubChem-compound SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 2.0 SMILES CC(=O)N[C@H]1[C@@H](O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O 2.0 1.0 1.0 SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O MurNAc-6-P ReactionCatalysis3329 ACTIVATION ReactionCatalysis3323 ACTIVATION 86-01-1 CAS 1.0 HMDB03556 HMDB PTS system mannose-specific EIIAB component Guanosine diphosphate mannose HMDB00042 HMDB HMDB01254 HMDB Phosphomannomutase 176 PubChem-compound HMDB00286 HMDB Mannose-1-phosphate guanylyltransferase SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O P69801 UniProt 1.0 1.0 ReactionCatalysis3330 ACTIVATION P69805 UniProt ReactionCatalysis3331 ACTIVATION SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O ADP-D-GLUCOSE BioCyc 7512-17-6 CAS ReactionCatalysis3332 ACTIVATION N-acetylmuramic acid 6-phosphate etherase N- acetylglucosamine- 6-phosphate deacetylase Glucosamine- 6-phosphate deaminase N-acetyl-D- glucosamine kinase Beta- hexosaminidase Probable bifunctional chitinase/lysozyme Probable bifunctional chitinase/lysozyme Phosphoglucomutase- 1 Glucose-1- phosphate adenylyltransferase Galactose-1- phosphate uridylyltransferase Mannose-6- phosphate isomerase Phosphomannomutase Mannose-1- phosphate guanylyltransferase GDP-mannose 4,6-dehydratase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase Phosphocarrier protein HPr Phosphocarrier protein HPr Glucose- specific phosphotransferase enzyme IIA component PTS system N-acetylmuramic acid-specific EIIBC component Phosphocarrier protein HPr Phosphocarrier protein HPr PTS system N- acetylglucosamine- specific EIICBA component Phosphocarrier protein HPr Glucose- specific phosphotransferase enzyme IIA component Phosphocarrier protein HPr MurNAc-6-P H 2 O D-Lactic acid N- Acetylglucosamine 6-phosphate N-Acetyl-D- Glucosamine 6-Phosphate H 2 O Acetic acid Glucosamine 6-phosphate H 2 O Ammonium β-D- fructofuranose 6-phosphate N-Acetyl-D- glucosamine ATP ADP H + H 2 O Chitobiose Chitin H 2 O Chitin Chitin H 2 O Chitin α-D-glucose 6-phosphate α-D-glucose 1-phosphate ATP ADP-glucose PP i UDP-galactose Uridine diphosphate glucose Galactose 1-phosphate α-D-mannose 6-phosphate α-D-mannose 1-phosphate GTP H + Guanosine diphosphate mannose PP i H 2 O GDP-4- dehydro-6- deoxy-α-D- mannose NADPH H + NADP GDP-β-L-fucose GDP-4- Dehydro-6-L- deoxygalactose MurNAc N-Acetyl-D- glucosamine Alpha-D-Glucose alpha-D-mannose PTS system mannose- specific EIIAB component Phosphocarrier protein HPr starch and sucrose metabolism Phosphocarrier protein HPr PTS system glucose- specific EIICB component Mannose permease IID component Mannose permease IIC component
388358 ChemSpider 388356 ChemSpider 6022 PubChem-compound 1.0 Phosphocarrier protein HPr GDP-mannose 4,6-dehydratase 937 ChemSpider Galactose-1-phosphate uridylyltransferase 16500 PubChem-compound HMDB00250 HMDB HMDB01341 HMDB 1.0 Reaction3311 false Chitin + Water → Chitin + N-Acetyl-D-glucosamine LEFT_TO_RIGHT Glucose-specific phosphotransferase enzyme IIA component 3.2.1.14 false 3.2.1.14 Chitin + Water → Chitin + Chitobiose LEFT_TO_RIGHT 1.0 1.0 1.0 C00446 KEGG Compound alpha-D-glucose-1-phosphate 1.0 3.2.1.52 false 3.2.1.52 Chitobiose + Water → 2 N-Acetyl-D-glucosamine LEFT_TO_RIGHT ATP BioCyc PTS system mannose-specific EIIAB component Probable bifunctional chitinase/lysozyme Glucose-1-phosphate adenylyltransferase C8H16NO9P N-Acetyl-D-Glucosamine 6-Phosphate 301.05627 H4N Ammonium 18.034374 C15H26N2O12 Chitobiose 426.14856 PTS system glucose-specific EIICB component C14830 KEGG Compound 559142 ChemSpider Mannose-6-phosphate isomerase 2.7.1.59 false 2.7.1.59 Adenosine triphosphate + N-Acetyl-D-glucosamine → Adenosine diphosphate + Hydrogen Ion + N-Acetyl-D-Glucosamine 6-Phosphate LEFT_TO_RIGHT 3.5.99.6 false 3.5.99.6 Glucosamine 6-phosphate + Water → Ammonium + β-D-fructofuranose 6-phosphate LEFT_TO_RIGHT 3.5.1.25 false 3.5.1.25 N-Acetyl-D-Glucosamine 6-Phosphate + Water → Acetic acid + Glucosamine 6-phosphate LEFT_TO_RIGHT 4.2.1.126 false 4.2.1.126 MurNAc-6-P + Water → D-Lactic acid + N-Acetylglucosamine 6-phosphate LEFT_TO_RIGHT C6H13O9P alpha-D-glucose-1-phosphate 260.02972 P0AA04 UniProt SMILES [Na+].[Na+].[H][C@]1(COP([O-])(=O)OP(O)(=O)OC2([H])O[C@]([H])(CO)[C@]([H])(O)[C@]([H])(O)[C@@]2([H])O)OC([H])(N2C=CC([O-])=NC2=O)[C@]([H])(O)[C@]1([H])O ReactionCatalysis5142 ACTIVATION D-LACTATE BioCyc 5742 ChemSpider 1.0 Probable bifunctional chitinase/lysozyme N-acetylglucosamine-6-phosphate deacetylase CHEBI:16474 ChEBI ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc HMDB59597 HMDB 17216232 ChemSpider Glucosamine 6-phosphate MurNAc-6-P 1.0 53477679 PubChem-compound α-D-glucose 6-phosphate 133-89-1 CAS 439174 PubChem-compound C00461 KEGG Compound SMILES C[C@@H](O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C([O-])=O 10326-41-7 CAS 1010 ChemSpider N-acetylmuramic acid PTS permease C01674 KEGG Compound P00946 UniProt HMDB41827 HMDB PPI BioCyc P76535 UniProt SMILES C[C@@H](O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@@H](O)[C@@H]1NC(C)=O)C([O-])=O BiologicalState109 Escherichia coli, Inner Membrane C15H22N2Na2O17P2 UDP-galactose 610.0189 BiologicalState108 Escherichia coli, Cytosol CHEBI:17029 ChEBI 1.0 C6H13O9P Galactose 1-phosphate 260.02972 C16H25N5O15P2 ADP-glucose 589.0822 1.0 C10H16N5O14P3 Guanosine triphosphate 522.99066 HMDB00215 HMDB 388319 ChemSpider Hydrogen Ion HMDB00217 HMDB C8H16NO9P N-Acetylglucosamine 6-phosphate 301.05627 C00352 KEGG Compound Cytosol Glucosamine-6-phosphate deaminase 2.0 SubPathwayInteraction1765 SubPathway1765Reaction SubPathwayReaction C00357 KEGG Compound 1.0 glucose PTS permease P0A6V1 UniProt Reaction3354 false UDP-galactose + alpha-D-glucose-1-phosphate → Galactose 1-phosphate + Uridine diphosphate glucose LEFT_TO_RIGHT Chitin ReactionCoupledTransport114 false HPr - phosphorylated + alpha-D-mannose → HPr + α-D-mannose 6-phosphate LEFT_TO_RIGHT 2.0 ReactionCatalysis3268 ACTIVATION ReactionCatalysis3269 ACTIVATION ReactionCatalysis3267 ACTIVATION HMDB01311 HMDB HMDB00221 HMDB 3616-42-0 CAS C00008 KEGG Compound C00006 KEGG Compound ReactionCoupledTransportCatalysis148 ACTIVATION ReactionCatalysis3272 ACTIVATION Hydrogen Ion CHEBI:18009 ChEBI C00001 KEGG Compound C11H18NO8 MurNAc 292.1038 CHEBI:18361 ChEBI C00005 KEGG Compound C00002 KEGG Compound Phosphocarrier protein HPr N-acetylglucosamine-6-phosphate deacetylase C6H12O6 Alpha-D-Glucose 180.06339 ReactionCatalysis3275 ACTIVATION ReactionCatalysis3273 ACTIVATION ReactionCatalysis3274 ACTIVATION 2.7.7.27 false 2.7.7.27 Adenosine triphosphate + alpha-D-glucose-1-phosphate → ADP-glucose + Pyrophosphate LEFT_TO_RIGHT 5.4.2.2 false 5.4.2.2 α-D-glucose 6-phosphate → α-D-glucose 1-phosphate LEFT_TO_RIGHT C11H17NO11P MurNAc-6-P 370.05557 Chitobiose C01342 KEGG Compound C00256 KEGG Compound C00498 KEGG Compound SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)C(=O)N1 C6H14NO8P Glucosamine 6-phosphate 259.04572 C00013 KEGG Compound Glucosamine-6-phosphate deaminase C00140 KEGG Compound NAD(P) BioCyc GDP-L-fucose synthase D-GLUCOSAMINE-6-P BioCyc ReactionCoupledTransport133 false Alpha-D-Glucose + HPr - phosphorylated → HPr + α-D-glucose 6-phosphate LEFT_TO_RIGHT 1.0 562 TAXONOMY H Hydrogen Ion 1.007825 N-acetylglucosamine-6-phosphate deacetylase C00029 KEGG Compound ReactionCoupledTransportCatalysis167 ACTIVATION glucose-1-phosphate adenylyltransferase 56-65-5 CAS 1.0 ReactionCoupledTransportCatalysis161 ACTIVATION Galactose 1-phosphate ReactionCoupledTransportCatalysis160 ACTIVATION C00267 KEGG Compound Guanosine triphosphate Reaction3363 false GDP-4-dehydro-6-deoxy-α-D-mannose + Hydrogen Ion + NADPH → GDP-β-L-fucose + NADP LEFT_TO_RIGHT ACET BioCyc 2.7.1.69 false 2.7.1.69 HPr - phosphorylated + N-Acetyl-D-glucosamine → HPr + N-Acetyl-D-Glucosamine 6-Phosphate LEFT_TO_RIGHT Reaction3362 false Guanosine diphosphate mannose → GDP-4-dehydro-6-deoxy-α-D-mannose + Water LEFT_TO_RIGHT Reaction3361 false Guanosine triphosphate + Hydrogen Ion + α-D-mannose 1-phosphate → Guanosine diphosphate mannose + Pyrophosphate LEFT_TO_RIGHT 5.4.2.8 false 5.4.2.8 α-D-mannose 6-phosphate ↔ α-D-mannose 1-phosphate REVERSIBLE 2.7.1.- false 2.7.1.- HPr - phosphorylated + MurNAc → HPr + MurNAc-6-P LEFT_TO_RIGHT 1.0 4.0 1.0 1.0 15642 ChemSpider 577-76-4 CAS C00033 KEGG Compound 4.0 2.0 Water 123912 PubChem-compound PTS system glucose-specific EIICB component SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 1.0 C00044 KEGG Compound P0AF18 UniProt 2140-58-1 CAS Mannose permease IID component Mannose permease IIC component SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 1.0 HMDB00538 HMDB 389821 ChemSpider 399508 ChemSpider SMILES CC(O)=O 7732-18-5 CAS C28H49N3O16 Chitin 683.3113 110443 ChemSpider Phosphomannomutase Mannose-1-phosphate guanylyltransferase ADP-glucose 53477726 PubChem-compound 492-62-6 CAS 14-N-ACETYL-BETA-D-GLUCOSAMINYLN1 BioCyc C10H16N5O13P3 Adenosine triphosphate 506.99576 HMDB00645 HMDB GDP-mannose 4,6-dehydratase 1.0 P24174 UniProt P24175 UniProt CHEBI:7212 ChEBI SMILES C[C@@H](O)C(O)=O N-Acetyl-D-Glucosamine 6-Phosphate P0A759 UniProt HMDB02817 HMDB 1.0 962 PubChem-compound N-Acetyl-D-Glucosamine 6-Phosphate N-Acetyl-D-glucosamine PW000941 PathWhiz SMILES OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O N-Acetylglucosamine 6-phosphate 5800 ChemSpider SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O P75959 UniProt C00080 KEGG Compound 1746-32-3 CAS CHEBI:42111 ChEBI α-D-glucose 1-phosphate SMILES OCC1OC(O)C(O)C(O)C1O SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O 58-64-0 CAS 22833609 PubChem-compound GTP BioCyc 71358 ChemSpider SMILES C[C@@H]1OC(OP(O)(=O)OP(O)(=O)OCC2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@H](O)C1=O P75949 UniProt C00096 KEGG Compound 2255-14-3 CAS Acetic acid 644102 PubChem-compound SMILES [H][C@]1(COP([O-])(=O)OP(O)(=O)O[C@@]2([H])O[C@]([H])(C)C(=O)[C@]([H])(O)[C@]2([H])O)O[C@@]([H])(N2C=NC3=C2NC(=N)N=C3[O-])[C@]([H])(O)[C@]1([H])O Glucose-specific phosphotransferase enzyme IIA component SMILES CC1OC(OP([O-])(=O)OP([O-])(=O)OCC2OC(C(O)C2O)N2C=NC3=C2NC(N)=NC3=O)C(O)C(O)C1O Phosphoglucomutase-1 22833512 PubChem-compound 1.0 18396 PubChem-compound H2O Water 18.010565 α-D-mannose 6-phosphate Ammonium 6.0 1.0 SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O N-acetylmuramic acid 6-phosphate etherase CHEBI:57273 ChEBI 1.0 102029-88-9 CAS 1.0 CHEBI:57634 ChEBI MurNAc CHEBI:58601 ChEBI CHEBI:58721 ChEBI GDP-4-DEHYDRO-6-L-DEOXYGALACTOSE BioCyc ReactionCatalysis2924 ACTIVATION 17215925 ChemSpider C2H4O2 Acetic acid 60.02113 C16H21N5O15P2 GDP-4-dehydro-6-deoxy-α-D-mannose 585.05206 α-D-mannose 1-phosphate C16H23N5O15P2 GDP-β-L-fucose 587.0677 64-19-7 CAS SMILES O 21252321 PubChem-compound Pyrophosphate N-acetylmuramic acid 6-phosphate etherase http://identifiers.org/smpdb/SMP00958 SMPDB Reaction5171 false Guanosine diphosphate mannose → GDP-4-Dehydro-6-L-deoxygalactose LEFT_TO_RIGHT GALACTOSE-1P BioCyc CHEBI:58225 ChEBI C3H6O3 D-Lactic acid 90.03169 ADP BioCyc P32055 UniProt ALPHA-D-GALACTOSYL-13-BETA-D-GALACTOS BioCyc N-ACETYL-D-GLUCOSAMINE-6-P BioCyc 53-59-8 CAS CHEBI:15820 ChEBI 1038 PubChem-compound Alpha-D-Glucose GO:0005829 GENE ONTOLOGY 1.0 1.0 CHITOBIOSE BioCyc 55423 ChemSpider N-Acetyl-D-glucosamine Pyrophosphate NADPH 6830 PubChem-compound GO:0070258 GENE ONTOLOGY NADP C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 C8H15NO6 N-Acetyl-D-glucosamine 221.08994 1.0 mannose PTS permease alpha-D-mannose α-D-mannose 6-phosphate NADPH BioCyc HMDB06557 HMDB 218 ChemSpider http://identifiers.org/smpdb/SMP00906 SMPDB 1.0 C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc P69797 UniProt Mannose permease IID component galactose-1-phosphate uridylyltransferase Amino sugar and nucleotide sugar metabolism II 1398-61-4 CAS 1.0 GDP-MANNOSE BioCyc PTS system N-acetylglucosamine-specific EIICBA component β-D-fructofuranose 6-phosphate Galactose-1-phosphate uridylyltransferase 2.0 P69783 UniProt 1.0 Inner Membrane SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O P69786 UniProt SMILES CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O 1.0 SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 1.0 PW000887 PathWhiz 1.0 Mannose permease IIC component 53-57-6 CAS 1.0 P77272 UniProt C6H11O9P β-D-fructofuranose 6-phosphate 258.01517 P09148 UniProt CHEBI:16955 ChEBI CHEBI:28938 ChEBI Mannose-6-phosphate isomerase C6H11O9P α-D-glucose 6-phosphate 258.01517 α-D-glucose 1-phosphate alpha-D-glucose-1-phosphate O7P2 Pyrophosphate 173.91193 Uridine diphosphate glucose 17372 ChemSpider 5957 PubChem-compound CHEBI:15751 ChEBI CHEBI:15873 ChEBI C6H11O9P α-D-mannose 6-phosphate 258.01517 CHEBI:15996 ChEBI 5.3.1.8 false 5.3.1.8 α-D-mannose 6-phosphate ↔ β-D-fructofuranose 6-phosphate REVERSIBLE C6H12O6 alpha-D-mannose 180.06339 CHEBI:57964 ChEBI GDP-β-L-fucose GDP-4-dehydro-6-deoxy-α-D-mannose P13656 UniProt 440996 PubChem-compound α-D-mannose 1-phosphate 1.0 Adenosine triphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 P36871 UniProt CHEBI:17925 ChEBI Beta-hexosaminidase P09323 UniProt N-acetyl-D-glucosamine kinase HMDB03362 HMDB CHEBI:58409 ChEBI HMDB01062 HMDB SMILES N[C@H]1[C@@H](O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O 2.0 14000-31-8 CAS PTS system N-acetylmuramic acid-specific EIIBC component 5675 ChemSpider N-acetyl-D-glucosamine kinase Phosphoglucomutase-1 N-acetylglucosamine PTS permease Adenosine diphosphate 14798-03-9 CAS α-D-glucose 6-phosphate CHEBI:15784 ChEBI 1.0 HMDB03345 HMDB CHEBI:15422 ChEBI β-D-fructofuranose 6-phosphate HMDB01163 HMDB 1.0 Beta-hexosaminidase 439217 PubChem-compound 439219 PubChem-compound Water SMILES [NH4+] CHEBI:17973 ChEBI UDP-galactose N-acetylmuramic acid 6-phosphate etherase GDP-L-fucose synthase CHEBI:28729 ChEBI SMILES CC(=O)N[C@H]1C(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O SMILES CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(O)=O)[C@@H]1O CHEBI:16761 ChEBI CHEBI:506227 ChEBI C16H23N5O15P2 GDP-4-Dehydro-6-L-deoxygalactose 587.0666 PTS system N-acetylglucosamine-specific EIICBA component GDP-4-Dehydro-6-L-deoxygalactose 1.0 starch and sucrose metabolism SubPathway CHEBI:15366 ChEBI C16H25N5O16P2 Guanosine diphosphate mannose 605.07715 Glucose-1-phosphate adenylyltransferase PTS system N-acetylmuramic acid-specific EIIBC component SMILES CC(=O)NC1[C@H](O)OC(CO)[C@@H](COC[C@@H]2OC(CO)[C@@H](COC[C@@H]3OC(CO)[C@@H](O)[C@H](O)C3NC(C)=O)[C@H](O)C2NC(C)=O)[C@@H]1O HMDB02111 HMDB 1.0 171 ChemSpider D-Lactic acid CHEBI:15377 ChEBI glucosamine-6-phosphate deaminase CHEBI:15378 ChEBI SMILES [H+] 6569 ChemSpider HMDB01391 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound HMDB01273 HMDB ReactionCatalysis3317 ACTIVATION 3123-67-9 CAS 1.0 ReactionCatalysis3318 ACTIVATION 79025 PubChem-compound 61503 PubChem-compound CHEBI:60332 ChEBI P0AC88 UniProt SMILES NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@H]3O)C2=NC=N1 16741146 PubChem-compound SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 2.0 SMILES CC(=O)N[C@H]1[C@@H](O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O 2.0 1.0 1.0 SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O MurNAc-6-P ReactionCatalysis3329 ACTIVATION ReactionCatalysis3323 ACTIVATION 86-01-1 CAS 1.0 HMDB03556 HMDB PTS system mannose-specific EIIAB component Guanosine diphosphate mannose HMDB00042 HMDB HMDB01254 HMDB Phosphomannomutase 176 PubChem-compound HMDB00286 HMDB Mannose-1-phosphate guanylyltransferase SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O P69801 UniProt 1.0 1.0 ReactionCatalysis3330 ACTIVATION P69805 UniProt ReactionCatalysis3331 ACTIVATION SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O ADP-D-GLUCOSE BioCyc 7512-17-6 CAS ReactionCatalysis3332 ACTIVATION