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6022 PubChem-compound C00556 KEGG Compound 2.0 Phosphocarrier protein HPr C23H38N7O17P3S Acetyl-CoA 809.1258 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 937 ChemSpider 439162 PubChem-compound ReactionCoupledTransportCatalysis172 ACTIVATION 1.0 HMDB00131 HMDB 46173312 PubChem-compound HMDB01341 HMDB Glucose-specific phosphotransferase enzyme IIA component 439278 PubChem-compound 2.0 439153 PubChem-compound 1.0 SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(C)C(=O)C2=CC=CC=C2C1=O)=C(\C)CCC=C(C)C 1.0 58238 ChemSpider CHEBI:16389 ChEBI HMDB01112 HMDB C6H14O12P2 Fructose 1,6-bisphosphate 339.99606 CHEBI:16027 ChEBI NAD Pyruvate kinase I ATP BioCyc HMDB00263 HMDB HMDB01473 HMDB PTS system glucose-specific EIICB component 1.2.4.1 false 1.2.4.1 Coenzyme A + NAD + Pyruvic acid → Acetyl-CoA + Carbon dioxide + NADH LEFT_TO_RIGHT Glycerophosphoryl diester phosphodiesterase 45479636 PubChem-compound P0AA04 UniProt 1.0 Glyceraldehyde-3-phosphate dehydrogenase A HMDB01206 HMDB Anaerobic glycerol-3-phosphate dehydrogenase subunit C Fructose-1,6-bisphosphatase class 1 6-phosphofructokinase II 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Fructose-bisphosphate aldolase class 1 5742 ChemSpider 6-phosphofructokinase I Fructose 1,6-bisphosphate 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HMDB59597 HMDB P0AD61 UniProt 5858 ChemSpider HMDB00243 HMDB HMDB00124 HMDB C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 HMDB00126 HMDB P0A9B2 UniProt 709 ChemSpider C00221 KEGG Compound Acetyl-CoA 704 ChemSpider Fructose-1,6-bisphosphatase class 2 1010 ChemSpider Anaerobic glycerol-3-phosphate dehydrogenase subunit A 2.7.1.30 false 2.7.1.30 Adenosine triphosphate + Glycerol → Adenosine diphosphate + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Glycerol 1.1.1.94 false 1.1.1.94 Glycerol 3-phosphate + Ubiquinone-1 → Dihydroxyacetone phosphate + Ubiquinol-1 LEFT_TO_RIGHT Glycerol kinase 1.1.5.3 false 1.1.5.3 Glycerol 3-phosphate + menaquinone-8 → Dihydroxyacetone phosphate + Menaquinol 8 LEFT_TO_RIGHT 488-69-7 CAS 4.0 Reaction3447 false glycerophosphoserine + Water → Benzyl alcohol + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(O)C2=CC=CC=C2C(O)=C1C)=C(\C)CCC=C(C)C C3H7O6P D-Glyceraldehyde 3-phosphate 169.99803 138-08-9 CAS BiologicalState109 2.0 1.0 HMDB01423 HMDB C00116 KEGG Compound SubPathwayInteraction1404 SubPathwayReaction SubPathway1404Reaction Hydrogen Ion C3H8O10P2 Glyceric acid 1,3-biphosphate 265.95926 Glycerol-3-phosphate dehydrogenase [NAD(P)+] C00111 KEGG Compound Uncharacterized protein yggF Enolase Cytosol C00236 KEGG Compound Glycerol uptake facilitator protein C00597 KEGG Compound glucose PTS permease C00354 KEGG Compound Adenosine triphosphate Glucose-6-phosphate isomerase P10908 UniProt C00009 KEGG Compound 4307 ChemSpider 1.0 C00008 KEGG Compound SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 C00001 KEGG Compound 3-Phosphoglyceric acid CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound C00002 KEGG Compound 1031 ChemSpider Phosphocarrier protein HPr HMDB01429 HMDB Menaquinol 8 C51H74O2 Menaquinol 8 718.5689 2.0 388411 ChemSpider 388538 ChemSpider C21H28N7O14P2 NAD 664.11694 447920 PubChem-compound C00011 KEGG Compound C00010 KEGG Compound FRUCTOSE-6P BioCyc 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT Glycerol-3-phosphate transporter 562 TAXONOMY CHEBI:17138 ChEBI H Hydrogen Ion 1.007825 D-Glyceraldehyde 3-phosphate 388308 ChemSpider C00022 KEGG Compound Unknown 56-65-5 CAS Glyceric acid 1,3-biphosphate 53-84-9 CAS C00020 KEGG Compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 1.0 Unknown 62713 ChemSpider C00024 KEGG Compound P0A796 UniProt Phosphoglycerate kinase P0A799 UniProt 2.0 Phosphatase ybhA P21829 UniProt 1.0 SMILES [NH3+]C(COP([O-])(=O)OCC(O)CO)C([O-])=O Phosphoenolpyruvate synthase C00399 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Unknown Benzyl alcohol Water AMP BioCyc 492-61-5 CAS PTS system glucose-specific EIICB component 753 PubChem-compound GLYCEROL BioCyc Glycerophosphoryl diester phosphodiesterase_ 648 ChemSpider SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O P13033 UniProt PHOSPHO-ENOL-PYRUVATE BioCyc P0A858 UniProt HMDB00538 HMDB 1.0 24.0 SMILES OC(=O)C(=C)OP(O)(O)=O 64689 PubChem-compound C3H7O7P 3-Phosphoglyceric acid 185.99294 668 PubChem-compound 7732-18-5 CAS 1.0 P0A991 UniProt SMILES COC1=C(O)C(C)=C(CC=C(C)C)C(O)=C1OC 591-59-3 CAS 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 triosephosphate isomerase 1.0 Triosephosphate isomerase P0A6S7 UniProt P06999 UniProt P0AER0 UniProt Transport420 false Phosphate (←), Glycerol 3-phosphate (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C10H16N5O13P3 Adenosine triphosphate 506.99576 DPG BioCyc DIHYDROXY-ACETONE-PHOSPHATE BioCyc 4.0 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 1.0 445557 PubChem-compound P0A6T1 UniProt P0A993 UniProt 2-Phospho-D-glyceric acid SMILES CC(=O)C(O)=O 663 ChemSpider P0A996 UniProt C3H7O7P 2-Phospho-D-glyceric acid 185.99294 C00074 KEGG Compound CHEBI:17050 ChEBI SMILES OCC(=O)COP(O)(O)=O HMDB01967 HMDB HMDB00516 HMDB 4.0 Transport421 false Glycerol (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 962 PubChem-compound Beta-D-Glucose 1.0 724 PubChem-compound 5800 ChemSpider CO2 Carbon dioxide 43.98983 Phosphate Ubiquinone-1 733 ChemSpider C00080 KEGG Compound 4.0 Periplasmic Space C00085 KEGG Compound Pyruvate kinase I C01172 KEGG Compound 729 PubChem-compound Glycerol 3-phosphate 14265-44-2 CAS CHEBI:44897 ChEBI PYRUVATE BioCyc 58-64-0 CAS Glyceraldehyde-3-phosphate dehydrogenase A Fructose-1,6-bisphosphatase class 1 Anaerobic glycerol-3-phosphate dehydrogenase subunit C glycerol metabolism V (glycerophosphoserine) G3P BioCyc GLYCEROL-3P BioCyc Fructose-bisphosphate aldolase class 1 ReactionCatalysis2902 ACTIVATION C00093 KEGG Compound 2.0 1.0 444493 PubChem-compound 6083 PubChem-compound 2-PG BioCyc Glucose-specific phosphotransferase enzyme IIA component PW000918 PathWhiz ACETYL-COA BioCyc Anaerobic glycerol-3-phosphate dehydrogenase subunit A 60.0 C7H8O Benzyl alcohol 108.05752 H2O Water 18.010565 SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O Fructose-1,6-bisphosphatase class 2 4.0 393165 ChemSpider NADH BioCyc NAD BioCyc SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 1.0 P37689 UniProt Carbon dioxide Glycerol-3-phosphate dehydrogenase [NAD(P)+] 1.0 Glycerol uptake facilitator protein 100-51-6 CAS SMILES OCC(O)CO 2.0 Uncharacterized protein yggF Enolase 980 ChemSpider CHEBI:15903 ChEBI P0A6P9 UniProt 820-11-1 CAS SMILES OC[C@@H](O)COP(O)(O)=O TransportCatalysis363 ACTIVATION glycerol-3-phosphate dehydrogenase (anaerobic) 244 PubChem-compound P08194 UniProt 2.0 SMILES OCC1=CC=CC=C1 NADH phosphoenolpyruvate synthetase enolase SMILES O 4.0 pyruvate kinase 56-81-5 CAS C10H14N5O7P Adenosine monophosphate 347.06308 C6H12O6 Beta-D-Glucose 180.06339 Glucose-6-phosphate isomerase HMDB00807 HMDB P62707 UniProt glycerophosphoserine C6H13O9P Beta-D-glucose 6-phosphate 260.02972 1005 PubChem-compound 34-DIMETHYLBENZYL-ALCOHOL BioCyc 643-13-0 CAS 1.0 1981-49-3 CAS Dihydroxyacetone phosphate glycerol channel GlpF 1.0 6816 PubChem-compound glycerophosphoryl diester phosphodiesterase, periplasmic C3H7O6P Dihydroxyacetone phosphate 169.99803 glycerol kinase Pyruvic acid CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 4.0 ReactionCatalysis2542 ACTIVATION TransportCatalysis364 ACTIVATION 1.0 C6H13NO8P glycerophosphoserine 258.03842 1.0 1038 PubChem-compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 GO:0005829 GENE ONTOLOGY ReactionCatalysis3405 ACTIVATION ReactionCatalysis3409 ACTIVATION ReactionCatalysis3406 ACTIVATION Adenosine monophosphate 274 ChemSpider CHEBI:16905 ChEBI HMDB00902 HMDB CHEBI:16908 ChEBI 1.0 O4P Phosphate 94.95342 C14H18O4 Ubiquinone-1 250.12051 Ubiquinol-1 GO:0070258 GENE ONTOLOGY Glycerol ReactionCatalysis3416 ACTIVATION ReactionCatalysis3417 ACTIVATION CHEBI:15946 ChEBI Phosphoglycerate kinase 5376507 PubChem-compound 1.0 683 PubChem-compound 58-68-4 CAS SMILES [O-]P([O-])([O-])=O CHEBI:61931 ChEBI C6H13O9P Fructose 6-phosphate 260.02972 124-38-9 CAS PW000779 PathWhiz P0A6F3 UniProt CHEBI:17835 ChEBI 5.3.1.1 false 5.3.1.1 D-Glyceraldehyde 3-phosphate ↔ Dihydroxyacetone phosphate REVERSIBLE SMILES COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O P69783 UniProt Inner Membrane ReactionCatalysis2622 ACTIVATION ReactionCatalysis2621 ACTIVATION Glycerol P69786 UniProt ReactionCatalysis2624 ACTIVATION C3H9O6P Glycerol 3-phosphate 172.01367 ReactionCatalysis2623 ACTIVATION ReactionCatalysis2626 ACTIVATION ReactionCatalysis2625 ACTIVATION ReactionCatalysis2628 ACTIVATION ReactionCatalysis2627 ACTIVATION 57-04-5 CAS CHEBI:44027 ChEBI Glycerol 3-phosphate C3H8O3 Glycerol 92.04734 69507 PubChem-compound Beta-D-glucose 6-phosphate SMP00802 SMPDB ReactionCatalysis2629 ACTIVATION SMILES O=C=O Glycerophosphoryl diester phosphodiesterase ReactionCatalysis2633 ACTIVATION ReactionCatalysis2632 ACTIVATION ReactionCatalysis2634 ACTIVATION Fructose 6-phosphate C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound Triosephosphate isomerase CHEBI:15978 ChEBI GO:0005620 GENE ONTOLOGY ReactionCatalysis2631 ACTIVATION Beta-D-Glucose 6-phosphate 1.0 ReactionCatalysis2630 ACTIVATION SMP00935 SMPDB 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 6-phosphofructokinase II 6-phosphofructokinase I phosphoglycerate mutase P09394 UniProt 6-phosphofructokinase-1 Adenosine diphosphate Glyceraldehyde 3-phosphate dehydrogenase C3H5O6P Phosphoenolpyruvic acid 167.98238 fructose bisphosphate aldolase fructose-1,6-bisphosphatase C10H15N5O10P2 Adenosine diphosphate 427.02942 phosphoglucose isomerase HMDB03391 HMDB fructose 1,6-bisphosphatase 2 Fructose-1,6-bisphosphatase 1 Phosphoenolpyruvic acid 1.0 menaquinone-8 CHEBI:17987 ChEBI CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 10.0 Glycerol kinase 5682 ChemSpider CHEBI:1146900 ChEBI Phosphate CO-A BioCyc 72-89-9 CAS HMDB03498 HMDB Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(COP(O)(O)=O)C(=O)OP(O)(O)=O 1.0 1.0 439427 PubChem-compound CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 388299 ChemSpider HMDB02012 HMDB P23538 UniProt 2.7.9.2 false 2.7.9.2 Adenosine monophosphate + 2 Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid + Water LEFT_TO_RIGHT P21599 UniProt 127-17-3 CAS 1.0 CHEBI:17719 ChEBI 2.7.1.40 false 2.7.1.40 Adenosine diphosphate + Hydrogen Ion + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid LEFT_TO_RIGHT HMDB01058 HMDB FRUCTOSE-16-DIPHOSPHATE BioCyc C51H72O2 menaquinone-8 716.5532 Reaction2638 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 1.0 4.2.1.11 false 4.2.1.11 2-Phospho-D-glyceric acid → Phosphoenolpyruvic acid + Water LEFT_TO_RIGHT CHEBI:16526 ChEBI HMDB03119 HMDB SMILES O[C@H]1[C@H](O)[C@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O Glycerol-3-phosphate transporter TCA cycle SubPathway 1.0 1.0 CHEBI:16761 ChEBI Glycerol 3-phosphate 1.0 2.7.2.3 false 2.7.2.3 Adenosine diphosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + Adenosine triphosphate LEFT_TO_RIGHT Reaction2637 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 4.1.2.13 false 4.1.2.13 Fructose 1,6-bisphosphate ↔ D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate REVERSIBLE 1.2.1.12 false 1.2.1.12 D-Glyceraldehyde 3-phosphate + NAD + Phosphate → Glyceric acid 1,3-biphosphate + Hydrogen Ion + NADH LEFT_TO_RIGHT 3.1.3.11 false 3.1.3.11 Fructose 6-phosphate + Phosphate → Fructose 1,6-bisphosphate + Water LEFT_TO_RIGHT Reaction2633 false Adenosine triphosphate + Fructose 6-phosphate → Adenosine diphosphate + Fructose 1,6-bisphosphate + Hydrogen Ion LEFT_TO_RIGHT 5.3.1.9 false 5.3.1.9 Beta-D-glucose 6-phosphate → Fructose 6-phosphate LEFT_TO_RIGHT P0A9C0 UniProt Unknown Unknown 392413 ChemSpider SMILES OC(COP(O)(O)=O)C(O)=O glycerol-3-phosphate dehydrogenase (aerobic) C14H20O4 Ubiquinol-1 252.13615 Phosphatase ybhA P0A9C9 UniProt C00631 KEGG Compound 1.0 5893 PubChem-compound HMDB02111 HMDB 1.0 Pyruvate dehydrogenase complex CHEBI:32816 ChEBI CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Phosphoenolpyruvate synthase CHEBI:16108 ChEBI 17989-41-2 CAS HMDB01270 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 60.0 Unknown SMILES OC[C@@H](OP(O)(O)=O)C(O)=O Phosphate 1.0 280 PubChem-compound 2.0 1.0 HMDB01487 HMDB 4462 PubChem-compound CHEBI:17522 ChEBI Glycerophosphoryl diester phosphodiesterase_ 2.0 SMILES OC(COP(O)(O)=O)C=O 10.0 P21437 UniProt 727-81-1 CAS 2.0 GAP BioCyc HMDB00045 HMDB 1060 PubChem-compound 1061 PubChem-compound C00661 KEGG Compound CHEBI:15351 ChEBI 13860335 ChemSpider 85-61-0 CAS P0AB71 UniProt CHEBI:61684 ChEBI Glycerol-3- phosphate transporter Glycerol uptake facilitator protein Glucose-6- phosphate isomerase Fructose-1,6- bisphosphatase class 2 Fructose-1,6- bisphosphatase class 1 Uncharacterized protein yggF Phosphatase ybhA 6- phosphofructokinase I 6- phosphofructokinase II Glyceraldehyde- 3-phosphate dehydrogenase A Phosphoglycerate kinase 2,3- bisphosphoglycerate- independent phosphoglycerate mutase 2,3- bisphosphoglycerate- dependent phosphoglycerate mutase Enolase Phosphoenolpyruvate synthase Pyruvate kinase I Pyruvate kinase II Unknown Unknown Unknown Unknown Fructose- bisphosphate aldolase class 1 Fructose- bisphosphate aldolase class 2 Triosephosphate isomerase Glycerol kinase Glycerol-3- phosphate dehydrogenase [NAD(P)+] Anaerobic glycerol-3- phosphate dehydrogenase subunit A Anaerobic glycerol-3- phosphate dehydrogenase subunit B Anaerobic glycerol-3- phosphate dehydrogenase subunit C Phosphocarrier protein HPr Phosphocarrier protein HPr PTS system glucose- specific EIICB component Glucose- specific phosphotransferase enzyme IIA component P i P i Glycerol 3-phosphate Glycerol 3-phosphate Glycerol Glycerol Beta-D-glucose 6-phosphate Fructose 6-phosphate P i Fructose 1,6- bisphosphate H 2 O ATP Fructose 1,6- bisphosphate ADP H + D- Glyceraldehyde 3-phosphate NAD P i Glyceric acid 1,3-biphosphate NADH H + ADP ATP 3- Phosphoglyceric acid 2-Phospho-D- glyceric acid 2-Phospho-D- glyceric acid Phosphoenolpyruvic acid H 2 O AMP P i H + ATP H 2 O Pyruvic acid ADP H + ATP Pyruvic acid CoA NAD Acetyl-CoA CO 2 NADH D- Glyceraldehyde 3-phosphate Dihydroxyacetone phosphate D- Glyceraldehyde 3-phosphate Glycerol ATP H + ADP Glycerol 3-phosphate glycerophosphoserine H 2 O H + Benzyl alcohol Ubiquinone-1 Dihydroxyacetone phosphate Ubiquinol-1 menaquinone-8 Menaquinol 8 Dihydroxyacetone phosphate Beta-D-Glucose 6-phosphate Beta-D-Glucose 6-phosphate Magnesium Glycerophosphoryl diester phosphodiesterase TCA cycle Glycerophosphoryl diester phosphodiesterase_ Calcium Magnesium
6022 PubChem-compound C00556 KEGG Compound 2.0 Phosphocarrier protein HPr C23H38N7O17P3S Acetyl-CoA 809.1258 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 937 ChemSpider 439162 PubChem-compound ReactionCoupledTransportCatalysis172 ACTIVATION 1.0 HMDB00131 HMDB 46173312 PubChem-compound HMDB01341 HMDB Glucose-specific phosphotransferase enzyme IIA component 439278 PubChem-compound 2.0 439153 PubChem-compound 1.0 SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(C)C(=O)C2=CC=CC=C2C1=O)=C(\C)CCC=C(C)C 1.0 58238 ChemSpider CHEBI:16389 ChEBI HMDB01112 HMDB C6H14O12P2 Fructose 1,6-bisphosphate 339.99606 CHEBI:16027 ChEBI NAD Pyruvate kinase I ATP BioCyc HMDB00263 HMDB HMDB01473 HMDB PTS system glucose-specific EIICB component 1.2.4.1 false 1.2.4.1 Coenzyme A + NAD + Pyruvic acid → Acetyl-CoA + Carbon dioxide + NADH LEFT_TO_RIGHT Glycerophosphoryl diester phosphodiesterase 45479636 PubChem-compound P0AA04 UniProt 1.0 Glyceraldehyde-3-phosphate dehydrogenase A HMDB01206 HMDB Anaerobic glycerol-3-phosphate dehydrogenase subunit C Fructose-1,6-bisphosphatase class 1 6-phosphofructokinase II 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Fructose-bisphosphate aldolase class 1 5742 ChemSpider 6-phosphofructokinase I Fructose 1,6-bisphosphate 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HMDB59597 HMDB P0AD61 UniProt 5858 ChemSpider HMDB00243 HMDB HMDB00124 HMDB C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 HMDB00126 HMDB P0A9B2 UniProt 709 ChemSpider C00221 KEGG Compound Acetyl-CoA 704 ChemSpider Fructose-1,6-bisphosphatase class 2 1010 ChemSpider Anaerobic glycerol-3-phosphate dehydrogenase subunit A 2.7.1.30 false 2.7.1.30 Adenosine triphosphate + Glycerol → Adenosine diphosphate + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Glycerol 1.1.1.94 false 1.1.1.94 Glycerol 3-phosphate + Ubiquinone-1 → Dihydroxyacetone phosphate + Ubiquinol-1 LEFT_TO_RIGHT Glycerol kinase 1.1.5.3 false 1.1.5.3 Glycerol 3-phosphate + menaquinone-8 → Dihydroxyacetone phosphate + Menaquinol 8 LEFT_TO_RIGHT 488-69-7 CAS 4.0 Reaction3447 false glycerophosphoserine + Water → Benzyl alcohol + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(O)C2=CC=CC=C2C(O)=C1C)=C(\C)CCC=C(C)C C3H7O6P D-Glyceraldehyde 3-phosphate 169.99803 138-08-9 CAS BiologicalState109 Escherichia coli, Inner Membrane 2.0 1.0 HMDB01423 HMDB C00116 KEGG Compound SubPathwayInteraction1404 SubPathwayReaction SubPathway1404Reaction Hydrogen Ion C3H8O10P2 Glyceric acid 1,3-biphosphate 265.95926 Glycerol-3-phosphate dehydrogenase [NAD(P)+] C00111 KEGG Compound Uncharacterized protein yggF Enolase Cytosol C00236 KEGG Compound Glycerol uptake facilitator protein C00597 KEGG Compound glucose PTS permease C00354 KEGG Compound Adenosine triphosphate Glucose-6-phosphate isomerase P10908 UniProt C00009 KEGG Compound 4307 ChemSpider 1.0 C00008 KEGG Compound SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 C00001 KEGG Compound 3-Phosphoglyceric acid CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound C00002 KEGG Compound 1031 ChemSpider Phosphocarrier protein HPr HMDB01429 HMDB Menaquinol 8 C51H74O2 Menaquinol 8 718.5689 2.0 388411 ChemSpider 388538 ChemSpider C21H28N7O14P2 NAD 664.11694 447920 PubChem-compound C00011 KEGG Compound C00010 KEGG Compound FRUCTOSE-6P BioCyc 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT Glycerol-3-phosphate transporter 562 TAXONOMY CHEBI:17138 ChEBI H Hydrogen Ion 1.007825 D-Glyceraldehyde 3-phosphate 388308 ChemSpider C00022 KEGG Compound Unknown 56-65-5 CAS Glyceric acid 1,3-biphosphate 53-84-9 CAS C00020 KEGG Compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 1.0 Unknown 62713 ChemSpider C00024 KEGG Compound P0A796 UniProt Phosphoglycerate kinase P0A799 UniProt 2.0 Phosphatase ybhA P21829 UniProt 1.0 SMILES [NH3+]C(COP([O-])(=O)OCC(O)CO)C([O-])=O Phosphoenolpyruvate synthase C00399 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Unknown Benzyl alcohol Water AMP BioCyc 492-61-5 CAS PTS system glucose-specific EIICB component 753 PubChem-compound GLYCEROL BioCyc Glycerophosphoryl diester phosphodiesterase_ 648 ChemSpider SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O P13033 UniProt PHOSPHO-ENOL-PYRUVATE BioCyc P0A858 UniProt HMDB00538 HMDB 1.0 24.0 SMILES OC(=O)C(=C)OP(O)(O)=O 64689 PubChem-compound C3H7O7P 3-Phosphoglyceric acid 185.99294 668 PubChem-compound 7732-18-5 CAS 1.0 P0A991 UniProt SMILES COC1=C(O)C(C)=C(CC=C(C)C)C(O)=C1OC 591-59-3 CAS 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 triosephosphate isomerase 1.0 Triosephosphate isomerase P0A6S7 UniProt P06999 UniProt P0AER0 UniProt Transport420 false Phosphate (←), Glycerol 3-phosphate (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C10H16N5O13P3 Adenosine triphosphate 506.99576 DPG BioCyc DIHYDROXY-ACETONE-PHOSPHATE BioCyc 4.0 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 1.0 445557 PubChem-compound P0A6T1 UniProt P0A993 UniProt 2-Phospho-D-glyceric acid SMILES CC(=O)C(O)=O 663 ChemSpider P0A996 UniProt C3H7O7P 2-Phospho-D-glyceric acid 185.99294 C00074 KEGG Compound CHEBI:17050 ChEBI SMILES OCC(=O)COP(O)(O)=O HMDB01967 HMDB HMDB00516 HMDB 4.0 Transport421 false Glycerol (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 962 PubChem-compound Beta-D-Glucose 1.0 724 PubChem-compound 5800 ChemSpider CO2 Carbon dioxide 43.98983 Phosphate Ubiquinone-1 733 ChemSpider C00080 KEGG Compound 4.0 Periplasmic Space C00085 KEGG Compound Pyruvate kinase I C01172 KEGG Compound 729 PubChem-compound Glycerol 3-phosphate 14265-44-2 CAS CHEBI:44897 ChEBI PYRUVATE BioCyc 58-64-0 CAS Glyceraldehyde-3-phosphate dehydrogenase A Fructose-1,6-bisphosphatase class 1 Anaerobic glycerol-3-phosphate dehydrogenase subunit C glycerol metabolism V (glycerophosphoserine) G3P BioCyc GLYCEROL-3P BioCyc Fructose-bisphosphate aldolase class 1 ReactionCatalysis2902 ACTIVATION C00093 KEGG Compound 2.0 1.0 444493 PubChem-compound 6083 PubChem-compound 2-PG BioCyc Glucose-specific phosphotransferase enzyme IIA component PW000918 PathWhiz ACETYL-COA BioCyc Anaerobic glycerol-3-phosphate dehydrogenase subunit A 60.0 C7H8O Benzyl alcohol 108.05752 H2O Water 18.010565 SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O Fructose-1,6-bisphosphatase class 2 4.0 393165 ChemSpider NADH BioCyc NAD BioCyc SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 1.0 P37689 UniProt Carbon dioxide Glycerol-3-phosphate dehydrogenase [NAD(P)+] 1.0 Glycerol uptake facilitator protein 100-51-6 CAS SMILES OCC(O)CO 2.0 Uncharacterized protein yggF Enolase 980 ChemSpider CHEBI:15903 ChEBI P0A6P9 UniProt 820-11-1 CAS SMILES OC[C@@H](O)COP(O)(O)=O TransportCatalysis363 ACTIVATION glycerol-3-phosphate dehydrogenase (anaerobic) 244 PubChem-compound P08194 UniProt 2.0 SMILES OCC1=CC=CC=C1 NADH phosphoenolpyruvate synthetase enolase SMILES O 4.0 pyruvate kinase 56-81-5 CAS C10H14N5O7P Adenosine monophosphate 347.06308 C6H12O6 Beta-D-Glucose 180.06339 Glucose-6-phosphate isomerase HMDB00807 HMDB P62707 UniProt glycerophosphoserine C6H13O9P Beta-D-glucose 6-phosphate 260.02972 1005 PubChem-compound 34-DIMETHYLBENZYL-ALCOHOL BioCyc 643-13-0 CAS 1.0 1981-49-3 CAS Dihydroxyacetone phosphate glycerol channel GlpF 1.0 6816 PubChem-compound glycerophosphoryl diester phosphodiesterase, periplasmic C3H7O6P Dihydroxyacetone phosphate 169.99803 glycerol kinase Pyruvic acid CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 4.0 ReactionCatalysis2542 ACTIVATION TransportCatalysis364 ACTIVATION 1.0 C6H13NO8P glycerophosphoserine 258.03842 1.0 1038 PubChem-compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 GO:0005829 GENE ONTOLOGY ReactionCatalysis3405 ACTIVATION ReactionCatalysis3409 ACTIVATION ReactionCatalysis3406 ACTIVATION Adenosine monophosphate 274 ChemSpider CHEBI:16905 ChEBI HMDB00902 HMDB CHEBI:16908 ChEBI 1.0 O4P Phosphate 94.95342 C14H18O4 Ubiquinone-1 250.12051 Ubiquinol-1 GO:0070258 GENE ONTOLOGY Glycerol ReactionCatalysis3416 ACTIVATION ReactionCatalysis3417 ACTIVATION TCA cycle SubPathway CHEBI:15946 ChEBI Phosphoglycerate kinase 5376507 PubChem-compound 1.0 683 PubChem-compound 58-68-4 CAS SMILES [O-]P([O-])([O-])=O CHEBI:61931 ChEBI C6H13O9P Fructose 6-phosphate 260.02972 124-38-9 CAS PW000779 PathWhiz P0A6F3 UniProt CHEBI:17835 ChEBI 5.3.1.1 false 5.3.1.1 D-Glyceraldehyde 3-phosphate ↔ Dihydroxyacetone phosphate REVERSIBLE SMILES COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O P69783 UniProt Inner Membrane ReactionCatalysis2622 ACTIVATION ReactionCatalysis2621 ACTIVATION Glycerol P69786 UniProt ReactionCatalysis2624 ACTIVATION C3H9O6P Glycerol 3-phosphate 172.01367 ReactionCatalysis2623 ACTIVATION ReactionCatalysis2626 ACTIVATION ReactionCatalysis2625 ACTIVATION ReactionCatalysis2628 ACTIVATION ReactionCatalysis2627 ACTIVATION 57-04-5 CAS CHEBI:44027 ChEBI Glycerol 3-phosphate C3H8O3 Glycerol 92.04734 69507 PubChem-compound Beta-D-glucose 6-phosphate http://identifiers.org/smpdb/SMP00802 SMPDB ReactionCatalysis2629 ACTIVATION SMILES O=C=O Glycerophosphoryl diester phosphodiesterase ReactionCatalysis2633 ACTIVATION ReactionCatalysis2632 ACTIVATION ReactionCatalysis2634 ACTIVATION Fructose 6-phosphate C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound Triosephosphate isomerase CHEBI:15978 ChEBI GO:0005620 GENE ONTOLOGY ReactionCatalysis2631 ACTIVATION Beta-D-Glucose 6-phosphate 1.0 ReactionCatalysis2630 ACTIVATION http://identifiers.org/smpdb/SMP00935 SMPDB 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 6-phosphofructokinase II 6-phosphofructokinase I phosphoglycerate mutase P09394 UniProt 6-phosphofructokinase-1 Adenosine diphosphate Glyceraldehyde 3-phosphate dehydrogenase C3H5O6P Phosphoenolpyruvic acid 167.98238 fructose bisphosphate aldolase fructose-1,6-bisphosphatase C10H15N5O10P2 Adenosine diphosphate 427.02942 phosphoglucose isomerase HMDB03391 HMDB fructose 1,6-bisphosphatase 2 Fructose-1,6-bisphosphatase 1 Phosphoenolpyruvic acid 1.0 menaquinone-8 CHEBI:17987 ChEBI CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 10.0 Glycerol kinase 5682 ChemSpider CHEBI:1146900 ChEBI Phosphate CO-A BioCyc 72-89-9 CAS HMDB03498 HMDB Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(COP(O)(O)=O)C(=O)OP(O)(O)=O 1.0 1.0 439427 PubChem-compound CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 388299 ChemSpider HMDB02012 HMDB P23538 UniProt 2.7.9.2 false 2.7.9.2 Adenosine monophosphate + 2 Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid + Water LEFT_TO_RIGHT P21599 UniProt 127-17-3 CAS 1.0 CHEBI:17719 ChEBI 2.7.1.40 false 2.7.1.40 Adenosine diphosphate + Hydrogen Ion + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid LEFT_TO_RIGHT HMDB01058 HMDB FRUCTOSE-16-DIPHOSPHATE BioCyc C51H72O2 menaquinone-8 716.5532 Reaction2638 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 1.0 4.2.1.11 false 4.2.1.11 2-Phospho-D-glyceric acid → Phosphoenolpyruvic acid + Water LEFT_TO_RIGHT CHEBI:16526 ChEBI HMDB03119 HMDB SMILES O[C@H]1[C@H](O)[C@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O Glycerol-3-phosphate transporter 1.0 1.0 CHEBI:16761 ChEBI Glycerol 3-phosphate 1.0 2.7.2.3 false 2.7.2.3 Adenosine diphosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + Adenosine triphosphate LEFT_TO_RIGHT Reaction2637 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 4.1.2.13 false 4.1.2.13 Fructose 1,6-bisphosphate ↔ D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate REVERSIBLE 1.2.1.12 false 1.2.1.12 D-Glyceraldehyde 3-phosphate + NAD + Phosphate → Glyceric acid 1,3-biphosphate + Hydrogen Ion + NADH LEFT_TO_RIGHT 3.1.3.11 false 3.1.3.11 Fructose 6-phosphate + Phosphate → Fructose 1,6-bisphosphate + Water LEFT_TO_RIGHT Reaction2633 false Adenosine triphosphate + Fructose 6-phosphate → Adenosine diphosphate + Fructose 1,6-bisphosphate + Hydrogen Ion LEFT_TO_RIGHT 5.3.1.9 false 5.3.1.9 Beta-D-glucose 6-phosphate → Fructose 6-phosphate LEFT_TO_RIGHT P0A9C0 UniProt Unknown Unknown 392413 ChemSpider SMILES OC(COP(O)(O)=O)C(O)=O glycerol-3-phosphate dehydrogenase (aerobic) C14H20O4 Ubiquinol-1 252.13615 Phosphatase ybhA P0A9C9 UniProt C00631 KEGG Compound 1.0 5893 PubChem-compound HMDB02111 HMDB 1.0 Pyruvate dehydrogenase complex CHEBI:32816 ChEBI CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Phosphoenolpyruvate synthase CHEBI:16108 ChEBI 17989-41-2 CAS HMDB01270 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 60.0 Unknown SMILES OC[C@@H](OP(O)(O)=O)C(O)=O Phosphate 1.0 280 PubChem-compound 2.0 1.0 HMDB01487 HMDB 4462 PubChem-compound CHEBI:17522 ChEBI Glycerophosphoryl diester phosphodiesterase_ 2.0 SMILES OC(COP(O)(O)=O)C=O 10.0 P21437 UniProt 727-81-1 CAS 2.0 GAP BioCyc HMDB00045 HMDB 1060 PubChem-compound 1061 PubChem-compound C00661 KEGG Compound CHEBI:15351 ChEBI 13860335 ChemSpider 85-61-0 CAS P0AB71 UniProt CHEBI:61684 ChEBI