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HMDB00254 HMDB CHEBI:16136 ChEBI 6022 PubChem-compound HMDB00257 HMDB Hydrogen sulfide ReactionCoupledTransportCatalysis179 ACTIVATION 937 ChemSpider CYS BioCyc HMDB00250 HMDB 123991 PubChem-compound HMDB00251 HMDB S2O3 BioCyc 4.0 HMDB01341 HMDB 1.0 18779926 PubChem-compound 50 ChemSpider 1.0 CHEBI:17359 ChEBI 2-Aminoacrylic acid Taurine import ATP-binding protein TauB C00320 KEGG Compound ethanesulfonate ATP BioCyc Betaine aldehyde ReactionCoupledTransportCatalysis183 ACTIVATION Alpha-ketoglutarate-dependent taurine dioxygenase H4N Ammonium 18.034374 2.0 3.0 14808-79-8 CAS 559142 ChemSpider P38038 UniProt 1.0 HMDB01448 HMDB 5742 ChemSpider C00576 KEGG Compound CHEBI:17561 ChEBI CHEBI:16474 ChEBI 952 ChemSpider Sulfite reductase [NADPH] flavoprotein alpha-component 1.0 HMDB59597 HMDB BETAINE_ALDEHYDE BioCyc 3.1.3.7 false 3.1.3.7 Phosphoadenosine phosphosulfate + Water ↔ Adenosine phosphosulfate + Phosphate REVERSIBLE HMDB00243 HMDB 1.0 HMDB01453 HMDB 4.0 P55734 UniProt Cysteine synthase B Sulfate/thiosulfate import ATP-binding protein cysA 7418-61-3 CAS C00224 KEGG Compound HMDB00240 HMDB 1010 ChemSpider CHEBI:15033 ChEBI 1.0 Adenylyl-sulfate kinase HMDB41827 HMDB PPI BioCyc 5666-16-0 CAS BiologicalState109 HMDB00574 HMDB Ammonium Hydrogen Ion 2.0 HMDB00217 HMDB Cytosol 2.0 Phosphoadenosine phosphosulfate reductase Sulfite reductase [NADPH] hemoprotein beta-component Adenosine triphosphate SUC BioCyc FMNH2 HMDB00208 HMDB C00009 KEGG Compound HMDB00221 HMDB C00008 KEGG Compound C00007 KEGG Compound C00006 KEGG Compound 5755 ChemSpider P0AG78 UniProt CHEBI:18009 ChEBI Phosphoadenosine phosphosulfate C00001 KEGG Compound CHEBI:18361 ChEBI Thiosulfate sulfurtransferase glpE C00005 KEGG Compound CHEBI:18367 ChEBI Taurine CHEBI:16189 ChEBI 1032 ChemSpider C00245 KEGG Compound 1.0 C00002 KEGG Compound 1031 ChemSpider 2.5.1.47 false 2.5.1.47 Hydrogen sulfide + O-Acetylserine ↔ Acetic acid + Hydrogen Ion + L-Cysteine REVERSIBLE 1.8.1.2 false 1.8.1.2 5 Hydrogen Ion + 3 NADPH + Sulfite → Hydrogen sulfide + NADP + 3 Water LEFT_TO_RIGHT 4.0 APS BioCyc P0A6V5 UniProt 2.8.1.1 false 2.8.1.1 Cyanide + Thiosulfate → Hydrogen Ion + Sulfite + Thiocyanate LEFT_TO_RIGHT 559060 ChemSpider 1.14.11.17 false 1.14.11.17 Oxoglutaric acid + Oxygen + Taurine → Aminoacetaldehyde + Carbon dioxide + Hydrogen Ion + Succinic acid + Sulfite LEFT_TO_RIGHT 1.8.4.8 false 1.8.4.8 Phosphoadenosine phosphosulfate + reduced thioredoxin → Adenosine 3',5'-diphosphate + Hydrogen Ion + Sulfite + oxidized thioredoxin LEFT_TO_RIGHT 3-mercaptopyruvate sulfurtransferase 1.0 HMDB01429 HMDB HMDB03609 HMDB 1.14.14.5 false 1.14.14.5 ethanesulfonate + FMNH2 + Oxygen → Betaine aldehyde + Flavin Mononucleotide + Hydrogen Ion + Sulfite + Water LEFT_TO_RIGHT 1.0 Reaction3466 false L-Cysteine → 2-Aminoacrylic acid + Hydrogen Ion + Hydrogen sulfide LEFT_TO_RIGHT HMDB01520 HMDB C3H5NO2 2-Aminoacrylic acid 87.03203 C5H12NO Betaine aldehyde 102.09189 1068 ChemSpider C00011 KEGG Compound C01342 KEGG Compound glycolysis and pyruvate dehydrogenase SubPathway Aliphatic sulfonates import ATP-binding protein SsuB CHEBI:17123 ChEBI Sulfate adenylyltransferase subunit 2 Taurine-binding periplasmic protein C00013 KEGG Compound NAD(P) BioCyc sulfate / thiosulfate / selenate / selenite ABC transporter CysAUWSbp Sulfate 562 TAXONOMY H2S Hydrogen sulfide 33.98772 CHEBI:16048 ChEBI H Hydrogen Ion 1.007825 1.0 SubPathwayInteraction1437 SubPathway1437Reaction SubPathwayReaction 3'(2'),5'-bisphosphate nucleotidase cysQ C00022 KEGG Compound 56-65-5 CAS 5653 ChemSpider C00026 KEGG Compound 1054 ChemSpider Thiosulfate sulfurtransferase PspE ACET BioCyc 482-67-7 CAS 1.0 2.0 C02218 KEGG Compound CHEBI:16094 ChEBI 52-90-4 CAS C00033 KEGG Compound C5H9NO4 O-Acetylserine 147.05316 SMILES CCS([O-])(=O)=O 328-50-7 CAS SMILES [O-]S([S-])(=O)=O Water SMILES OC(=O)CCC(O)=O tryptophanase / L-cysteine desulfhydrase ReactionCatalysis2813 ACTIVATION C00283 KEGG Compound Protein malY ReactionCatalysis2814 ACTIVATION C10H14N5O10PS Adenosine phosphosulfate 427.0199 SMILES NCCS(O)(=O)=O SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 10238 PubChem-compound C00042 KEGG Compound Cysteine synthase A L-Cysteine CHEBI:61909 ChEBI SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Sulfate adenylyltransferase subunit 1 1.0 P0A853 UniProt SMILES C#[N-] HMDB00538 HMDB SO3 BioCyc C10H15N5O13P2S Phosphoadenosine phosphosulfate 506.98624 P0AAI1 UniProt 140102 ChemSpider C00177 KEGG Compound SMILES [O-]S([O-])(=O)=O SMILES CC(O)=O P0ABK5 UniProt C00054 KEGG Compound C00053 KEGG Compound 7732-18-5 CAS 1.0 C00059 KEGG Compound Putative aliphatic sulfonates transport permease protein ssuC SMILES [S-]C#N Sulfate transport system permease protein cysW 2-iminopropanoate Adenosine phosphosulfate C00061 KEGG Compound Tryptophanase P16676 UniProt P75851 UniProt P75853 UniProt C17H23N4O9P FMNH2 458.12027 1.0 146-17-8 CAS C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:18022 ChEBI 1.0 10214 PubChem-compound O-Acetylserine 485-84-7 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H]1O SMILES CC(=O)C(O)=O Taurine transport system permease protein tauC SMILES [O-]S([O-])=O Transport429 false Taurine (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT HMDB01967 HMDB 962 PubChem-compound 5800 ChemSpider Taurine import ATP-binding protein TauB CO2 Carbon dioxide 43.98983 Phosphate Alpha-ketoglutarate-dependent taurine dioxygenase C00080 KEGG Compound CHEBI:77456 ChEBI SMILES O=O Periplasmic Space Oxoglutaric acid Sulfate-binding protein 1.0 sulfur metabolism (ethanesulfonate) 1.0 14265-44-2 CAS PYRUVATE BioCyc 58-64-0 CAS 9322 PubChem-compound Putative aliphatic sulfonates-binding protein 1.0 C00094 KEGG Compound ACETYLSERINE BioCyc PW000925 PathWhiz 644102 PubChem-compound C3H7NO2S L-Cysteine 121.01975 Taurine SMILES NCC=O P17846 UniProt C00097 KEGG Compound 1.0 22833512 PubChem-compound Sulfite reductase [NADPH] flavoprotein alpha-component H2O Water 18.010565 Cysteine synthase B 57-12-5 CAS 393046 ChemSpider 14265-45-3 CAS 2.0 977 PubChem-compound Cystathionine beta-lyase metC P06721 UniProt Carbon dioxide Sulfite reductase [NADPH] hemoprotein beta-component 110510 ChemSpider P17854 UniProt Phosphoadenosine phosphosulfate reductase Sulfate transport system permease protein cysT Adenosine diphosphate cystathionine-β-lyase / L-cysteine desulfhydrase bifunctional β-cystathionase, PLP-dependent and regulator of maltose regulon 1.0 SMILES CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2 Sulfate-binding protein 17215925 ChemSpider C2H4O2 Acetic acid 60.02113 SMP00942 SMPDB Reaction2902 true 2-Aminoacrylic acid → 2-iminopropanoate LEFT_TO_RIGHT 249 PubChem-compound Reaction2903 true 2-iminopropanoate + Hydrogen Ion + Water → Ammonium + Pyruvic acid LEFT_TO_RIGHT SMILES N[C@@H](CS)C(O)=O 2.0 O4S Sulfate 95.95173 5975 PubChem-compound C2H5NO Aminoacetaldehyde 59.037113 Succinic acid Taurine CNS Thiocyanate 57.975143 64-19-7 CAS Thiosulfate sulfurtransferase glpE Thiosulfate SMILES O 2.0 Pyrophosphate 5147-00-2 CAS TransportCatalysis372 ACTIVATION 3717105 PubChem-compound 1123 PubChem-compound P16701 UniProt Sulfate/thiosulfate import ATP-binding protein cysA ethanesulfonate P16703 UniProt 1.0 Sulfate adenylyltransferase subunit 2 Sulfite Taurine-binding periplasmic protein 1.0 244 ChemSpider P22255 UniProt 51 PubChem-compound 89874 ChemSpider Adenosine 3',5'-diphosphate Pyruvic acid P0A6J1 UniProt ADP BioCyc C10H15N5O10P2 Adenosine 3',5'-diphosphate 427.02942 C3H4O3 Pyruvic acid 88.016045 O3S Sulfite 79.95682 1.0 1.0 53-59-8 CAS SMILES CC(=O)OC[C@H](N)C(O)=O 1038 PubChem-compound 1.0 SMILES CC(=N)C([O-])=O C2H5O3S ethanesulfonate 108.99649 Thiocyanate GO:0005829 GENE ONTOLOGY FMN BioCyc P23256 UniProt SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](O)[C@H]1O 274 ChemSpider C5H6O5 Oxoglutaric acid 146.02153 391 ChemSpider 1.0 CHEBI:15710 ChEBI 4.0 445395 PubChem-compound Sulfate O4P Phosphate 94.95342 taurine ABC transporter NADPH 5862 PubChem-compound Acetic acid GO:0070258 GENE ONTOLOGY 1948-56-7 CAS NADP C21H30N7O17P3 NADPH 745.0911 3-5-ADP BioCyc 302-04-5 CAS C21H29N7O17P3 NADP 744.08325 Thiosulfate sulfurtransferase PspE Sulfate transport system permease protein cysT Alkanesulfonate monooxygenase oxidized thioredoxin NADPH BioCyc reduced thioredoxin 1053-73-2 CAS PW000785 PathWhiz CPD-6641 BioCyc 4.0 218 ChemSpider Sulfate transport system permease protein cysW C3H4NO2 2-iminopropanoate 86.02475 P0AEB0 UniProt Cysteine synthase A SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O Oxygen CHEBI:30915 ChEBI 124-38-9 CAS Hydrogen Ion HSCN BioCyc HMDB02084 HMDB 9799 ChemSpider Inner Membrane CHEBI:15891 ChEBI SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 6971051 PubChem-compound 159296 PubChem-compound 7783-06-4 CAS Flavin Mononucleotide C17H21N4O9P Flavin Mononucleotide 456.1046 CHEBI:17709 ChEBI 53-57-6 CAS CHEBI:15741 ChEBI SMILES O=C=O CHEBI:28938 ChEBI 1110 PubChem-compound SMP00807 SMPDB C2H7NO3S Taurine 125.01466 O7P2 Pyrophosphate 173.91193 P21156 UniProt 1117 PubChem-compound 1.0 5957 PubChem-compound P37610 UniProt GO:0005620 GENE ONTOLOGY O3S2 Thiosulfate 111.92889 Tryptophanase C4H6O4 Succinic acid 118.02661 3'-phospho-adenylylsulfate reductase Aminoacetaldehyde sulfite reductase sulfate adenylyltransferase adenylylsulfate kinase reduced thioredoxin HMDB03276 HMDB Adenosine diphosphate Cyanide O-acetylserine sulfhydrylase A C10H15N5O10P2 Adenosine diphosphate 427.02942 CHN Cyanide 27.010899 2.0 Taurine transport system permease protein tauC CHEBI:17985 ChEBI SMILES NC(=C)C(O)=O CHEBI:17621 ChEBI Adenosine triphosphate 3.0 1085 ChemSpider CPD-8587 BioCyc Adenylyl-sulfate kinase CHEBI:17981 ChEBI 1099 PubChem-compound SMILES C[N+](C)(C)CC=O CHEBI:17980 ChEBI oxidized thioredoxin 5.0 1091 ChemSpider 1.0 14000-31-8 CAS Phosphate 1084 PubChem-compound Inner membrane protein YgaP CHEBI:17514 ChEBI 1.0 5675 ChemSpider Putative aliphatic sulfonates-binding protein 1078 ChemSpider SMILES S HMDB03011 HMDB ReactionCoupledTransport149 false ethanesulfonate + Adenosine triphosphate + Water → ethanesulfonate + Adenosine diphosphate + Hydrogen Ion + Phosphate LEFT_TO_RIGHT 14798-03-9 CAS ReactionCoupledTransport145 false Adenosine triphosphate + Sulfate + Water → Adenosine diphosphate + Hydrogen Ion + Phosphate + Sulfate LEFT_TO_RIGHT CHEBI:17628 ChEBI 2.7.7.4 false 2.7.7.4 Adenosine triphosphate + Hydrogen Ion + Sulfate → Adenosine phosphosulfate + Pyrophosphate LEFT_TO_RIGHT 2.7.1.25 false 2.7.1.25 Adenosine phosphosulfate + Adenosine triphosphate → Adenosine diphosphate + Hydrogen Ion + Phosphoadenosine phosphosulfate LEFT_TO_RIGHT 1.0 Water NH42SO4 BioCyc 2.0 CHEBI:15422 ChEBI P80645 UniProt 643976 PubChem-compound C00979 KEGG Compound 2.0 aliphatic sulfonate ABC transporter 3-mercaptopyruvate sulfurtransferase Cystathionine beta-lyase metC 9821 ChemSpider O2 Oxygen 31.98983 1.0 127-17-3 CAS 1.0 SMILES [NH4+] 107-35-7 CAS CHEBI:16526 ChEBI Q47537 UniProt 1.0 8961 ChemSpider Q47539 UniProt Q47538 UniProt CHEBI:16761 ChEBI 7782-44-7 CAS Aliphatic sulfonates import ATP-binding protein SsuB 1.0 P31142 UniProt CHEBI:15366 ChEBI 3'(2'),5'-bisphosphate nucleotidase cysQ 2-KETOGLUTARATE BioCyc C01847 KEGG Compound 1.0 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](OP(O)(O)=O)[C@H]1O HMDB01142 HMDB 1.0 HMDB02111 HMDB PAPS BioCyc SMILES CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=C(N2)C(=O)NC(=O)N1 110-15-6 CAS cysteine synthase B alkanesulfonate monooxygenase, FMNH2-dependent thiosulfate sulfurtransferase 4.0 171 ChemSpider Inner membrane protein YgaP CHEBI:32816 ChEBI CHEBI:15377 ChEBI CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Protein malY Putative aliphatic sulfonates transport permease protein ssuC HMDB00061 HMDB 5886 PubChem-compound ReactionCatalysis3437 ACTIVATION 1.0 ReactionCatalysis3435 ACTIVATION 1.0 ReactionCatalysis3436 ACTIVATION 2.0 280 PubChem-compound ReactionCatalysis3439 ACTIVATION HMDB01003 HMDB 16741146 PubChem-compound 1.0 Sulfate adenylyltransferase subunit 1 1.0 1.0 P23857 UniProt HS BioCyc FMNH2 BioCyc ReactionCatalysis3446 ACTIVATION ReactionCatalysis3447 ACTIVATION ReactionCatalysis3440 ACTIVATION ReactionCatalysis3441 ACTIVATION ReactionCatalysis3444 ACTIVATION ReactionCatalysis3445 ACTIVATION ReactionCatalysis3442 ACTIVATION ReactionCatalysis3443 ACTIVATION HMDB01377 HMDB 1060 PubChem-compound HMDB01134 HMDB 1061 PubChem-compound C01755 KEGG Compound 14383-50-7 CAS HMDB01252 HMDB HMDB00042 HMDB 1.0 Alkanesulfonate monooxygenase 176 PubChem-compound P23845 UniProt 8.0 ReactionCatalysis3450 ACTIVATION 1.0 Taurine-binding periplasmic protein Taurine transport system permease protein tauC Taurine import ATP-binding protein TauB Sulfate adenylyltransferase subunit 2 Sulfate adenylyltransferase subunit 1 Adenylyl- sulfate kinase 3'(2'),5'- bisphosphate nucleotidase cysQ Phosphoadenosine phosphosulfate reductase Alpha- ketoglutarate- dependent taurine dioxygenase Thiosulfate sulfurtransferase glpE Thiosulfate sulfurtransferase PspE 3- mercaptopyruvate sulfurtransferase Membrane protein Sulfite reductase [NADPH] flavoprotein alpha-component Sulfite reductase [NADPH] hemoprotein beta-component Protein malY Cystathionine beta-lyase metC Cysteine synthase B Cysteine synthase A Tryptophanase Alkanesulfonate monooxygenase Sulfate-binding protein Sulfate transport system permease protein cysW Sulfate transport system permease protein cysT Sulfate/thiosulfate import ATP-binding protein cysA Putative aliphatic sulfonates- binding protein Putative aliphatic sulfonates transport permease protein ssuC Aliphatic sulfonates import ATP-binding protein SsuB Taurine Taurine ATP H + Sulfate Adenosine phosphosulfate PP i ATP Phosphoadenosine phosphosulfate ADP H + H 2 O P i Adenosine phosphosulfate Sulfite H + Adenosine 3',5'- diphosphate Oxoglutaric acid O 2 Sulfite Succinic acid CO 2 H + Aminoacetaldehyde Cyanide Thiosulfate Thiocyanate Sulfite H + NADPH H + H 2 O NADP Hydrogen sulfide O-Acetylserine L-Cysteine Acetic acid H + H + Hydrogen sulfide 2-Aminoacrylic acid 2- iminopropanoate H 2 O H + Ammonium Pyruvic acid ethanesulfonate O 2 FMNH2 H + H 2 O Flavin Mononucleotide Sulfite Betaine aldehyde ATP H 2 O Sulfate ADP P i H + ATP H 2 O ethanesulfonate H + P i ADP Magnesium Pyridoxal 5'-phosphate reduced thioredoxin oxidized thioredoxin glycolysis and pyruvate dehydrogenase Cysteine synthase B Cysteine synthase A Pyridoxal 5'-phosphate
HMDB00254 HMDB CHEBI:16136 ChEBI 6022 PubChem-compound HMDB00257 HMDB Hydrogen sulfide ReactionCoupledTransportCatalysis179 ACTIVATION 937 ChemSpider CYS BioCyc HMDB00250 HMDB 123991 PubChem-compound HMDB00251 HMDB S2O3 BioCyc 4.0 HMDB01341 HMDB 1.0 18779926 PubChem-compound 50 ChemSpider 1.0 CHEBI:17359 ChEBI 2-Aminoacrylic acid Taurine import ATP-binding protein TauB C00320 KEGG Compound ethanesulfonate ATP BioCyc Betaine aldehyde ReactionCoupledTransportCatalysis183 ACTIVATION Alpha-ketoglutarate-dependent taurine dioxygenase H4N Ammonium 18.034374 2.0 3.0 14808-79-8 CAS 559142 ChemSpider P38038 UniProt 1.0 HMDB01448 HMDB 5742 ChemSpider C00576 KEGG Compound CHEBI:17561 ChEBI CHEBI:16474 ChEBI 952 ChemSpider Sulfite reductase [NADPH] flavoprotein alpha-component 1.0 HMDB59597 HMDB BETAINE_ALDEHYDE BioCyc 3.1.3.7 false 3.1.3.7 Phosphoadenosine phosphosulfate + Water ↔ Adenosine phosphosulfate + Phosphate REVERSIBLE HMDB00243 HMDB 1.0 HMDB01453 HMDB 4.0 P55734 UniProt Cysteine synthase B Sulfate/thiosulfate import ATP-binding protein cysA 7418-61-3 CAS C00224 KEGG Compound HMDB00240 HMDB 1010 ChemSpider CHEBI:15033 ChEBI 1.0 Adenylyl-sulfate kinase HMDB41827 HMDB PPI BioCyc 5666-16-0 CAS BiologicalState109 Escherichia coli, Inner Membrane HMDB00574 HMDB Ammonium Hydrogen Ion 2.0 HMDB00217 HMDB Cytosol 2.0 Phosphoadenosine phosphosulfate reductase Sulfite reductase [NADPH] hemoprotein beta-component Adenosine triphosphate SUC BioCyc FMNH2 HMDB00208 HMDB C00009 KEGG Compound HMDB00221 HMDB C00008 KEGG Compound C00007 KEGG Compound C00006 KEGG Compound 5755 ChemSpider P0AG78 UniProt CHEBI:18009 ChEBI Phosphoadenosine phosphosulfate C00001 KEGG Compound CHEBI:18361 ChEBI Thiosulfate sulfurtransferase glpE C00005 KEGG Compound CHEBI:18367 ChEBI Taurine CHEBI:16189 ChEBI 1032 ChemSpider C00245 KEGG Compound 1.0 C00002 KEGG Compound 1031 ChemSpider 2.5.1.47 false 2.5.1.47 Hydrogen sulfide + O-Acetylserine ↔ Acetic acid + Hydrogen Ion + L-Cysteine REVERSIBLE 1.8.1.2 false 1.8.1.2 5 Hydrogen Ion + 3 NADPH + Sulfite → Hydrogen sulfide + NADP + 3 Water LEFT_TO_RIGHT 4.0 APS BioCyc P0A6V5 UniProt 2.8.1.1 false 2.8.1.1 Cyanide + Thiosulfate → Hydrogen Ion + Sulfite + Thiocyanate LEFT_TO_RIGHT 559060 ChemSpider 1.14.11.17 false 1.14.11.17 Oxoglutaric acid + Oxygen + Taurine → Aminoacetaldehyde + Carbon dioxide + Hydrogen Ion + Succinic acid + Sulfite LEFT_TO_RIGHT 1.8.4.8 false 1.8.4.8 Phosphoadenosine phosphosulfate + reduced thioredoxin → Adenosine 3',5'-diphosphate + Hydrogen Ion + Sulfite + oxidized thioredoxin LEFT_TO_RIGHT 3-mercaptopyruvate sulfurtransferase 1.0 HMDB01429 HMDB HMDB03609 HMDB 1.14.14.5 false 1.14.14.5 ethanesulfonate + FMNH2 + Oxygen → Betaine aldehyde + Flavin Mononucleotide + Hydrogen Ion + Sulfite + Water LEFT_TO_RIGHT 1.0 Reaction3466 false L-Cysteine → 2-Aminoacrylic acid + Hydrogen Ion + Hydrogen sulfide LEFT_TO_RIGHT HMDB01520 HMDB C3H5NO2 2-Aminoacrylic acid 87.03203 C5H12NO Betaine aldehyde 102.09189 1068 ChemSpider C00011 KEGG Compound C01342 KEGG Compound Aliphatic sulfonates import ATP-binding protein SsuB CHEBI:17123 ChEBI Sulfate adenylyltransferase subunit 2 Taurine-binding periplasmic protein C00013 KEGG Compound NAD(P) BioCyc sulfate / thiosulfate / selenate / selenite ABC transporter CysAUWSbp Sulfate 562 TAXONOMY H2S Hydrogen sulfide 33.98772 CHEBI:16048 ChEBI H Hydrogen Ion 1.007825 1.0 SubPathwayInteraction1437 SubPathway1437Reaction SubPathwayReaction 3'(2'),5'-bisphosphate nucleotidase cysQ C00022 KEGG Compound 56-65-5 CAS 5653 ChemSpider C00026 KEGG Compound 1054 ChemSpider Thiosulfate sulfurtransferase PspE ACET BioCyc 482-67-7 CAS 1.0 2.0 C02218 KEGG Compound CHEBI:16094 ChEBI 52-90-4 CAS C00033 KEGG Compound C5H9NO4 O-Acetylserine 147.05316 SMILES CCS([O-])(=O)=O 328-50-7 CAS SMILES [O-]S([S-])(=O)=O Water SMILES OC(=O)CCC(O)=O tryptophanase / L-cysteine desulfhydrase ReactionCatalysis2813 ACTIVATION C00283 KEGG Compound Protein malY ReactionCatalysis2814 ACTIVATION C10H14N5O10PS Adenosine phosphosulfate 427.0199 SMILES NCCS(O)(=O)=O SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 10238 PubChem-compound C00042 KEGG Compound Cysteine synthase A L-Cysteine CHEBI:61909 ChEBI SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Sulfate adenylyltransferase subunit 1 1.0 P0A853 UniProt SMILES C#[N-] HMDB00538 HMDB SO3 BioCyc C10H15N5O13P2S Phosphoadenosine phosphosulfate 506.98624 P0AAI1 UniProt 140102 ChemSpider C00177 KEGG Compound SMILES [O-]S([O-])(=O)=O SMILES CC(O)=O P0ABK5 UniProt C00054 KEGG Compound C00053 KEGG Compound 7732-18-5 CAS 1.0 C00059 KEGG Compound Putative aliphatic sulfonates transport permease protein ssuC SMILES [S-]C#N Sulfate transport system permease protein cysW 2-iminopropanoate Adenosine phosphosulfate C00061 KEGG Compound Tryptophanase P16676 UniProt P75851 UniProt P75853 UniProt C17H23N4O9P FMNH2 458.12027 1.0 146-17-8 CAS C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:18022 ChEBI 1.0 10214 PubChem-compound O-Acetylserine 485-84-7 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H]1O SMILES CC(=O)C(O)=O Taurine transport system permease protein tauC SMILES [O-]S([O-])=O Transport429 false Taurine (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT HMDB01967 HMDB 962 PubChem-compound 5800 ChemSpider Taurine import ATP-binding protein TauB CO2 Carbon dioxide 43.98983 Phosphate Alpha-ketoglutarate-dependent taurine dioxygenase C00080 KEGG Compound CHEBI:77456 ChEBI SMILES O=O Periplasmic Space Oxoglutaric acid Sulfate-binding protein 1.0 sulfur metabolism (ethanesulfonate) 1.0 14265-44-2 CAS PYRUVATE BioCyc 58-64-0 CAS 9322 PubChem-compound Putative aliphatic sulfonates-binding protein 1.0 C00094 KEGG Compound ACETYLSERINE BioCyc PW000925 PathWhiz 644102 PubChem-compound C3H7NO2S L-Cysteine 121.01975 Taurine SMILES NCC=O P17846 UniProt C00097 KEGG Compound 1.0 22833512 PubChem-compound Sulfite reductase [NADPH] flavoprotein alpha-component H2O Water 18.010565 Cysteine synthase B 57-12-5 CAS 393046 ChemSpider 14265-45-3 CAS 2.0 977 PubChem-compound Cystathionine beta-lyase metC P06721 UniProt Carbon dioxide Sulfite reductase [NADPH] hemoprotein beta-component 110510 ChemSpider P17854 UniProt Phosphoadenosine phosphosulfate reductase Sulfate transport system permease protein cysT Adenosine diphosphate cystathionine-β-lyase / L-cysteine desulfhydrase bifunctional β-cystathionase, PLP-dependent and regulator of maltose regulon 1.0 SMILES CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2 Sulfate-binding protein 17215925 ChemSpider C2H4O2 Acetic acid 60.02113 http://identifiers.org/smpdb/SMP00942 SMPDB Reaction2902 true 2-Aminoacrylic acid → 2-iminopropanoate LEFT_TO_RIGHT 249 PubChem-compound Reaction2903 true 2-iminopropanoate + Hydrogen Ion + Water → Ammonium + Pyruvic acid LEFT_TO_RIGHT SMILES N[C@@H](CS)C(O)=O 2.0 O4S Sulfate 95.95173 5975 PubChem-compound C2H5NO Aminoacetaldehyde 59.037113 Succinic acid Taurine CNS Thiocyanate 57.975143 64-19-7 CAS Thiosulfate sulfurtransferase glpE Thiosulfate SMILES O 2.0 Pyrophosphate 5147-00-2 CAS TransportCatalysis372 ACTIVATION 3717105 PubChem-compound 1123 PubChem-compound P16701 UniProt Sulfate/thiosulfate import ATP-binding protein cysA ethanesulfonate P16703 UniProt 1.0 Sulfate adenylyltransferase subunit 2 Sulfite Taurine-binding periplasmic protein 1.0 244 ChemSpider P22255 UniProt 51 PubChem-compound 89874 ChemSpider Adenosine 3',5'-diphosphate Pyruvic acid P0A6J1 UniProt ADP BioCyc C10H15N5O10P2 Adenosine 3',5'-diphosphate 427.02942 C3H4O3 Pyruvic acid 88.016045 O3S Sulfite 79.95682 1.0 1.0 53-59-8 CAS SMILES CC(=O)OC[C@H](N)C(O)=O 1038 PubChem-compound 1.0 SMILES CC(=N)C([O-])=O C2H5O3S ethanesulfonate 108.99649 Thiocyanate GO:0005829 GENE ONTOLOGY FMN BioCyc P23256 UniProt SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](O)[C@H]1O 274 ChemSpider C5H6O5 Oxoglutaric acid 146.02153 391 ChemSpider 1.0 CHEBI:15710 ChEBI 4.0 445395 PubChem-compound Sulfate O4P Phosphate 94.95342 taurine ABC transporter NADPH 5862 PubChem-compound Acetic acid GO:0070258 GENE ONTOLOGY 1948-56-7 CAS NADP C21H30N7O17P3 NADPH 745.0911 3-5-ADP BioCyc 302-04-5 CAS C21H29N7O17P3 NADP 744.08325 Thiosulfate sulfurtransferase PspE glycolysis and pyruvate dehydrogenase SubPathway Sulfate transport system permease protein cysT Alkanesulfonate monooxygenase oxidized thioredoxin NADPH BioCyc reduced thioredoxin 1053-73-2 CAS PW000785 PathWhiz CPD-6641 BioCyc 4.0 218 ChemSpider Sulfate transport system permease protein cysW C3H4NO2 2-iminopropanoate 86.02475 P0AEB0 UniProt Cysteine synthase A SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O Oxygen CHEBI:30915 ChEBI 124-38-9 CAS Hydrogen Ion HSCN BioCyc HMDB02084 HMDB 9799 ChemSpider Inner Membrane CHEBI:15891 ChEBI SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 6971051 PubChem-compound 159296 PubChem-compound 7783-06-4 CAS Flavin Mononucleotide C17H21N4O9P Flavin Mononucleotide 456.1046 CHEBI:17709 ChEBI 53-57-6 CAS CHEBI:15741 ChEBI SMILES O=C=O CHEBI:28938 ChEBI 1110 PubChem-compound http://identifiers.org/smpdb/SMP00807 SMPDB C2H7NO3S Taurine 125.01466 O7P2 Pyrophosphate 173.91193 P21156 UniProt 1117 PubChem-compound 1.0 5957 PubChem-compound P37610 UniProt GO:0005620 GENE ONTOLOGY O3S2 Thiosulfate 111.92889 Tryptophanase C4H6O4 Succinic acid 118.02661 3'-phospho-adenylylsulfate reductase Aminoacetaldehyde sulfite reductase sulfate adenylyltransferase adenylylsulfate kinase reduced thioredoxin HMDB03276 HMDB Adenosine diphosphate Cyanide O-acetylserine sulfhydrylase A C10H15N5O10P2 Adenosine diphosphate 427.02942 CHN Cyanide 27.010899 2.0 Taurine transport system permease protein tauC CHEBI:17985 ChEBI SMILES NC(=C)C(O)=O CHEBI:17621 ChEBI Adenosine triphosphate 3.0 1085 ChemSpider CPD-8587 BioCyc Adenylyl-sulfate kinase CHEBI:17981 ChEBI 1099 PubChem-compound SMILES C[N+](C)(C)CC=O CHEBI:17980 ChEBI oxidized thioredoxin 5.0 1091 ChemSpider 1.0 14000-31-8 CAS Phosphate 1084 PubChem-compound Inner membrane protein YgaP CHEBI:17514 ChEBI 1.0 5675 ChemSpider Putative aliphatic sulfonates-binding protein 1078 ChemSpider SMILES S HMDB03011 HMDB ReactionCoupledTransport149 false ethanesulfonate + Adenosine triphosphate + Water → ethanesulfonate + Adenosine diphosphate + Hydrogen Ion + Phosphate LEFT_TO_RIGHT 14798-03-9 CAS ReactionCoupledTransport145 false Adenosine triphosphate + Sulfate + Water → Adenosine diphosphate + Hydrogen Ion + Phosphate + Sulfate LEFT_TO_RIGHT CHEBI:17628 ChEBI 2.7.7.4 false 2.7.7.4 Adenosine triphosphate + Hydrogen Ion + Sulfate → Adenosine phosphosulfate + Pyrophosphate LEFT_TO_RIGHT 2.7.1.25 false 2.7.1.25 Adenosine phosphosulfate + Adenosine triphosphate → Adenosine diphosphate + Hydrogen Ion + Phosphoadenosine phosphosulfate LEFT_TO_RIGHT 1.0 Water NH42SO4 BioCyc 2.0 CHEBI:15422 ChEBI P80645 UniProt 643976 PubChem-compound C00979 KEGG Compound 2.0 aliphatic sulfonate ABC transporter 3-mercaptopyruvate sulfurtransferase Cystathionine beta-lyase metC 9821 ChemSpider O2 Oxygen 31.98983 1.0 127-17-3 CAS 1.0 SMILES [NH4+] 107-35-7 CAS CHEBI:16526 ChEBI Q47537 UniProt 1.0 8961 ChemSpider Q47539 UniProt Q47538 UniProt CHEBI:16761 ChEBI 7782-44-7 CAS Aliphatic sulfonates import ATP-binding protein SsuB 1.0 P31142 UniProt CHEBI:15366 ChEBI 3'(2'),5'-bisphosphate nucleotidase cysQ 2-KETOGLUTARATE BioCyc C01847 KEGG Compound 1.0 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](OP(O)(O)=O)[C@H]1O HMDB01142 HMDB 1.0 HMDB02111 HMDB PAPS BioCyc SMILES CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=C(N2)C(=O)NC(=O)N1 110-15-6 CAS cysteine synthase B alkanesulfonate monooxygenase, FMNH2-dependent thiosulfate sulfurtransferase 4.0 171 ChemSpider Inner membrane protein YgaP CHEBI:32816 ChEBI CHEBI:15377 ChEBI CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Protein malY Putative aliphatic sulfonates transport permease protein ssuC HMDB00061 HMDB 5886 PubChem-compound ReactionCatalysis3437 ACTIVATION 1.0 ReactionCatalysis3435 ACTIVATION 1.0 ReactionCatalysis3436 ACTIVATION 2.0 280 PubChem-compound ReactionCatalysis3439 ACTIVATION HMDB01003 HMDB 16741146 PubChem-compound 1.0 Sulfate adenylyltransferase subunit 1 1.0 1.0 P23857 UniProt HS BioCyc FMNH2 BioCyc ReactionCatalysis3446 ACTIVATION ReactionCatalysis3447 ACTIVATION ReactionCatalysis3440 ACTIVATION ReactionCatalysis3441 ACTIVATION ReactionCatalysis3444 ACTIVATION ReactionCatalysis3445 ACTIVATION ReactionCatalysis3442 ACTIVATION ReactionCatalysis3443 ACTIVATION HMDB01377 HMDB 1060 PubChem-compound HMDB01134 HMDB 1061 PubChem-compound C01755 KEGG Compound 14383-50-7 CAS HMDB01252 HMDB HMDB00042 HMDB 1.0 Alkanesulfonate monooxygenase 176 PubChem-compound P23845 UniProt 8.0 ReactionCatalysis3450 ACTIVATION 1.0