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Isocitrate lyase Isocitrate lyase Malate synthase G Citrate synthase monomer Aconitate hydratase 2 Uncharacterized protein ybhJ Aconitate hydratase 1 Malate dehydrogenase Hydroxypropanedioic acid Citric acid H 2 O cis-Aconitic acid Isocitric acid Succinic acid Glyoxylic acid H 2 O Acetyl-CoA CoA H + L-Malic acid trans-Aconitic acid Oxalacetic acid H 2 O Acetyl-CoA CoA H + H 2 O Isocitric acid NAD Oxalacetic acid NADH H + Magnesium Magnesium Aconitate hydratase 1 Aconitate hydratase 2
aceA aceA glcB gltA acnB ybhJ acnA mdh Hydroxypropanedioic acid Citric acid Water cis-Aconitic acid Isocitric acid Succinic acid Glyoxylic acid Water Acetyl-CoA Coenzyme A Hydrogen Ion L-Malic acid trans-Aconitic acid Oxalacetic acid Water Acetyl-CoA Coenzyme A Hydrogen Ion Water Isocitric acid NAD Oxalacetic acid NADH Hydrogen Ion acnA acnB