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Chorismate-- pyruvate lyase Octaprenyl- diphosphate synthase 4- hydroxybenzoate octaprenyltransferase 3-octaprenyl- 4- hydroxybenzoate carboxy-lyase 2- octaprenylphenol hydroxylase 3- demethylubiquinone- 9 3- methyltransferase 2-octaprenyl- 6- methoxyphenol hydroxylase Ubiquinone/menaquinone biosynthesis methyltransferase ubiE 2-octaprenyl- 3-methyl-6- methoxy-1,4- benzoquinol hydroxylase 3- demethylubiquinone- 9 3- methyltransferase Chorismate Pyruvic acid 4- Hydroxybenzoic acid Farnesyl pyrophosphate Isopentenyl pyrophosphate PP i Octaprenyl diphosphate Octaprenyl diphosphate PP i 3-Octaprenyl- 4- hydroxybenzoate H + CO 2 2- Octaprenylphenol H + NADPH O 2 NADP H 2 O 2-Octaprenyl- 6- hydroxyphenol S- Adenosylmethionine H + S- Adenosylhomocysteine 2-methoxy-6- (all-trans- octaprenyl)phenol H + NADPH O 2 H 2 O NADP 2-methoxy-6-all trans- octaprenyl-2- methoxy-1,4- benzoquinol S- Adenosylmethionine S- Adenosylhomocysteine H + 6-Methoxy-3- methyl-2-all- trans- octaprenyl- 1,4- benzoquinol O 2 H 2 O 3- demethylubiquinol- 8 S- Adenosylmethionine H + S- Adenosylhomocysteine Ubiquinol 8 Magnesium Magnesium Manganese Zinc Zinc Reduced acceptor oxidized electron acceptor Chorismate Biosynthesis Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis Oxidative Phosphorylation
ubiC ispB ubiA ubiD ubiI ubiG ubiH ubiE ubiF ubiG Chorismate Pyruvic acid 4- Hydroxybenzoic acid Farnesyl pyrophosphate Isopentenyl pyrophosphate Pyrophosphate Octaprenyl diphosphate Octaprenyl diphosphate Pyrophosphate 3-Octaprenyl- 4- hydroxybenzoate Hydrogen Ion Carbon dioxide 2- Octaprenylphenol Hydrogen Ion NADPH Oxygen NADP Water 2-Octaprenyl- 6- hydroxyphenol S- Adenosylmethionine Hydrogen Ion S- Adenosylhomocysteine 2-methoxy-6- (all-trans- octaprenyl)phenol Hydrogen Ion NADPH Oxygen Water NADP 2-methoxy-6-all trans- octaprenyl-2- methoxy-1,4- benzoquinol S- Adenosylmethionine S- Adenosylhomocysteine Hydrogen Ion 6-Methoxy-3- methyl-2-all- trans- octaprenyl- 1,4- benzoquinol Oxygen Water 3- demethylubiquinol- 8 S- Adenosylmethionine Hydrogen Ion S- Adenosylhomocysteine Ubiquinol 8 Reduced acceptor oxidized electron acceptor Chorismate Biosynthesis Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis Oxidative Phosphorylation