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C4H8O2 Butyric acid 88.05243 C23H38N7O17P3S Acetyl-CoA 809.1258 439161 PubChem-compound 937 ChemSpider Butyryl-CoA 388353 ChemSpider 259 ChemSpider NADH ReactionCatalysis3743 ACTIVATION ReactionCatalysis3744 ACTIVATION 439153 PubChem-compound SMILES O Acetoacetyl-CoA fatty acid oxidation (Butanoate) ReactionCatalysis3741 ACTIVATION ReactionCatalysis3742 ACTIVATION 1.0 ReactionCatalysis3740 ACTIVATION CHEBI:57371 ChEBI NAD ATP BioCyc 3-ketoacyl-CoA thiolase 1.0 Short-chain-fatty-acid--CoA ligase 6816 PubChem-compound CHEBI:15846 ChEBI 102680-35-3 CAS PW001019 PathWhiz PW001017 PathWhiz HMDB01206 HMDB 1.0 CHEBI:15380 ChEBI 5742 ChemSpider 5280381 PubChem-compound 1038 PubChem-compound C25H40N7O19P3S Succinyl-CoA 867.1312 265 PubChem-compound 264 PubChem-compound C00332 KEGG Compound 440045 PubChem-compound HMDB59597 HMDB C25H40N7O17P3S Crotonoyl-CoA 835.1414 HMDB00902 HMDB CHEBI:16908 ChEBI Butyric acid Acetyl-CoA CHEBI:30772 ChEBI 1010 ChemSpider 107-92-6 CAS SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS 260 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCSC(=O)CCC(O)=O HMDB01423 HMDB Hydrogen Ion P76082 UniProt CHEBI:5086 ChEBI Adenosine triphosphate 4444072 ChemSpider 58-68-4 CAS SMILES C\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 Reduced electron-transfer flavoprotein 1.0 C00001 KEGG Compound C00246 KEGG Compound CPD-1083 BioCyc C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1.0 Fatty acid oxidation complex subunit alpha an oxidized electron-transfer flavoprotein  SMILES C[C@@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N fatty acid oxidation (hexanoate) SubPathway C21H28N7O14P2 NAD 664.11694 P21151 UniProt C00010 KEGG Compound 3-ketoacyl-CoA thiolase_ C00136 KEGG Compound 3-ketoacyl-CoA thiolase Short-chain-fatty-acid--CoA ligase HMDB01088 HMDB SubPathwayInteraction2087 SubPathwayReaction SubPathway2087Reaction C25H40N7O18P3S Acetoacetyl-CoA 851.13635 C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound 2,3-dehydroadipyl-CoA hydratase P76503 UniProt P77399 UniProt H Hydrogen Ion 1.007825 C25H42N7O17P3S Butyryl-CoA 837.15704 388307 ChemSpider 56-65-5 CAS 53-84-9 CAS C00024 KEGG Compound ReactionCatalysis3732 ACTIVATION P38135 UniProt 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 1.0 2-METHYL-3-HYDROXY-BUTYRYL-COA BioCyc 5682 ChemSpider Reduced electron-transfer flavoprotein SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Fatty acid oxidation complex subunit alpha_ Water 2871-66-1 CAS SMILES CC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N FadJ component of anaerobic fatty acid oxidation complex CO-A BioCyc 72-89-9 CAS CPD-12174 BioCyc CHEBI:15452 ChEBI SMILES CCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 389056 ChemSpider Coenzyme A 1.0 C21H36N7O16P3S Coenzyme A 767.11523 C03561 KEGG Compound 604-98-8 CAS HMDB00538 HMDB ACETOACETYL-COA BioCyc 1.0 CHEBI:15422 ChEBI 6557 ChemSpider SMILES CCCC(O)=O SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS 388299 ChemSpider Fatty acid oxidation complex subunit alpha HMDB01166 HMDB 2140-48-9 CAS 439214 PubChem-compound 1.0 C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 3-ketoacyl-CoA thiolase_ 2,3-dehydroadipyl-CoA hydratase 1.0 962 PubChem-compound C00877 KEGG Compound 392413 ChemSpider 2.0 Crotonoyl-CoA C25H42N7O18P3S 3-Hydroxybutyryl-CoA 853.152 5893 PubChem-compound HMDB02111 HMDB HMDB01022 HMDB C00080 KEGG Compound Reaction3758 false Adenosine triphosphate + Butyric acid + Coenzyme A → Adenosine triphosphate + Butyryl-CoA LEFT_TO_RIGHT SMP01035 SMPDB 1420-36-6 CAS SMP01033 SMPDB CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Succinyl-CoA HMDB02009 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Fatty acid oxidation complex subunit alpha_ C00091 KEGG Compound 1.0 HMDB01487 HMDB CHEBI:15345 ChEBI 444493 PubChem-compound HMDB00039 HMDB acetyl-CoA C-acyltransferase HMDB01484 HMDB B7L9A7 UniProt an oxidized electron-transfer flavoprotein  Reaction3770 false Acetoacetyl-CoA + Coenzyme A → Acetyl-CoA + Succinyl-CoA LEFT_TO_RIGHT ACETYL-COA BioCyc H2O Water 18.010565 NADH BioCyc 3-METHYLBENZYLSUCCINYL-COA BioCyc NAD BioCyc 3-Hydroxybutyryl-CoA CHEBI:15351 ChEBI CHEBI:15473 ChEBI 85-61-0 CAS Reaction3769 false 3-Hydroxybutyryl-CoA + NAD → Acetoacetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT Reaction3768 false Crotonoyl-CoA → 3-Hydroxybutyryl-CoA + Water LEFT_TO_RIGHT Reaction3767 false 3-Hydroxybutyryl-CoA → Crotonoyl-CoA LEFT_TO_RIGHT 1.0 Reaction3766 true Butyryl-CoA + Hydrogen Ion + an oxidized electron-transfer flavoprotein  → Crotonoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT 1.0 Short-chain- fatty-acid-- CoA ligase 2,3- dehydroadipyl- CoA hydratase 2,3- dehydroadipyl- CoA hydratase Fatty acid oxidation complex subunit alpha_ Fatty acid oxidation complex subunit alpha 3-ketoacyl-CoA thiolase_ 3-ketoacyl-CoA thiolase Butyric acid CoA ATP ATP Butyryl-CoA H + Crotonoyl-CoA H 2 O 3- Hydroxybutyryl- CoA NAD NADH H + Acetoacetyl-CoA 3- Hydroxybutyryl- CoA CoA Acetyl-CoA Succinyl-CoA an oxidized electron- transfer flavoprotein Reduced electron- transfer flavoprotein fatty acid oxidation (hexanoate)
C4H8O2 Butyric acid 88.05243 C23H38N7O17P3S Acetyl-CoA 809.1258 439161 PubChem-compound 937 ChemSpider Butyryl-CoA 388353 ChemSpider 259 ChemSpider NADH ReactionCatalysis3743 ACTIVATION ReactionCatalysis3744 ACTIVATION 439153 PubChem-compound SMILES O Acetoacetyl-CoA fatty acid oxidation (Butanoate) ReactionCatalysis3741 ACTIVATION ReactionCatalysis3742 ACTIVATION 1.0 ReactionCatalysis3740 ACTIVATION CHEBI:57371 ChEBI NAD ATP BioCyc 3-ketoacyl-CoA thiolase 1.0 Short-chain-fatty-acid--CoA ligase 6816 PubChem-compound CHEBI:15846 ChEBI 102680-35-3 CAS PW001019 PathWhiz PW001017 PathWhiz HMDB01206 HMDB 1.0 CHEBI:15380 ChEBI 5742 ChemSpider 5280381 PubChem-compound 1038 PubChem-compound C25H40N7O19P3S Succinyl-CoA 867.1312 265 PubChem-compound 264 PubChem-compound C00332 KEGG Compound 440045 PubChem-compound HMDB59597 HMDB C25H40N7O17P3S Crotonoyl-CoA 835.1414 HMDB00902 HMDB CHEBI:16908 ChEBI Butyric acid Acetyl-CoA CHEBI:30772 ChEBI 1010 ChemSpider 107-92-6 CAS SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS 260 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCSC(=O)CCC(O)=O HMDB01423 HMDB Hydrogen Ion P76082 UniProt CHEBI:5086 ChEBI Adenosine triphosphate 4444072 ChemSpider 58-68-4 CAS SMILES C\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 Reduced electron-transfer flavoprotein 1.0 C00001 KEGG Compound C00246 KEGG Compound CPD-1083 BioCyc C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1.0 Fatty acid oxidation complex subunit alpha an oxidized electron-transfer flavoprotein  SMILES C[C@@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N C21H28N7O14P2 NAD 664.11694 P21151 UniProt C00010 KEGG Compound 3-ketoacyl-CoA thiolase_ C00136 KEGG Compound 3-ketoacyl-CoA thiolase Short-chain-fatty-acid--CoA ligase HMDB01088 HMDB SubPathwayInteraction2087 SubPathwayReaction SubPathway2087Reaction C25H40N7O18P3S Acetoacetyl-CoA 851.13635 C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound 2,3-dehydroadipyl-CoA hydratase P76503 UniProt P77399 UniProt H Hydrogen Ion 1.007825 C25H42N7O17P3S Butyryl-CoA 837.15704 388307 ChemSpider 56-65-5 CAS 53-84-9 CAS C00024 KEGG Compound ReactionCatalysis3732 ACTIVATION P38135 UniProt 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 1.0 2-METHYL-3-HYDROXY-BUTYRYL-COA BioCyc 5682 ChemSpider Reduced electron-transfer flavoprotein SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Fatty acid oxidation complex subunit alpha_ Water 2871-66-1 CAS SMILES CC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N FadJ component of anaerobic fatty acid oxidation complex CO-A BioCyc 72-89-9 CAS CPD-12174 BioCyc CHEBI:15452 ChEBI SMILES CCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 389056 ChemSpider Coenzyme A 1.0 C21H36N7O16P3S Coenzyme A 767.11523 C03561 KEGG Compound 604-98-8 CAS HMDB00538 HMDB ACETOACETYL-COA BioCyc 1.0 CHEBI:15422 ChEBI 6557 ChemSpider SMILES CCCC(O)=O SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS 388299 ChemSpider Fatty acid oxidation complex subunit alpha HMDB01166 HMDB 2140-48-9 CAS 439214 PubChem-compound 1.0 C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 3-ketoacyl-CoA thiolase_ 2,3-dehydroadipyl-CoA hydratase 1.0 962 PubChem-compound C00877 KEGG Compound 392413 ChemSpider 2.0 fatty acid oxidation (hexanoate) SubPathway Crotonoyl-CoA C25H42N7O18P3S 3-Hydroxybutyryl-CoA 853.152 5893 PubChem-compound HMDB02111 HMDB HMDB01022 HMDB C00080 KEGG Compound Reaction3758 false Adenosine triphosphate + Butyric acid + Coenzyme A → Adenosine triphosphate + Butyryl-CoA LEFT_TO_RIGHT http://identifiers.org/smpdb/SMP01035 SMPDB 1420-36-6 CAS http://identifiers.org/smpdb/SMP01033 SMPDB CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Succinyl-CoA HMDB02009 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Fatty acid oxidation complex subunit alpha_ C00091 KEGG Compound 1.0 HMDB01487 HMDB CHEBI:15345 ChEBI 444493 PubChem-compound HMDB00039 HMDB acetyl-CoA C-acyltransferase HMDB01484 HMDB B7L9A7 UniProt an oxidized electron-transfer flavoprotein  Reaction3770 false Acetoacetyl-CoA + Coenzyme A → Acetyl-CoA + Succinyl-CoA LEFT_TO_RIGHT ACETYL-COA BioCyc H2O Water 18.010565 NADH BioCyc 3-METHYLBENZYLSUCCINYL-COA BioCyc NAD BioCyc 3-Hydroxybutyryl-CoA CHEBI:15351 ChEBI CHEBI:15473 ChEBI 85-61-0 CAS Reaction3769 false 3-Hydroxybutyryl-CoA + NAD → Acetoacetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT Reaction3768 false Crotonoyl-CoA → 3-Hydroxybutyryl-CoA + Water LEFT_TO_RIGHT Reaction3767 false 3-Hydroxybutyryl-CoA → Crotonoyl-CoA LEFT_TO_RIGHT 1.0 Reaction3766 true Butyryl-CoA + Hydrogen Ion + an oxidized electron-transfer flavoprotein  → Crotonoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT 1.0 fadK paaF paaF fadJ fadB fadI fadA Butyric acid Coenzyme A Adenosine triphosphate Adenosine triphosphate Butyryl-CoA Hydrogen Ion Crotonoyl-CoA Water 3- Hydroxybutyryl- CoA NAD NADH Hydrogen Ion Acetoacetyl-CoA 3- Hydroxybutyryl- CoA Coenzyme A Acetyl-CoA Succinyl-CoA an oxidized electron- transfer flavoprotein Reduced electron- transfer flavoprotein fatty acid oxidation (hexanoate)