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1.0 C23H38N7O17P3S Acetyl-CoA 809.1258 65113 PubChem-compound 78303-19-2 CAS 17220833 ChemSpider 937 ChemSpider NADH 439153 PubChem-compound 3Z-dodecenoyl-CoA SMILES O C10H14N5O7P Adenosine monophosphate 347.06308 1.0 C33H58N7O17P3S Lauroyl-CoA 949.2823 CHEBI:16027 ChEBI NAD PW001020 PathWhiz ATP BioCyc PW001021 PathWhiz ReactionCatalysis3756 ACTIVATION Reaction3784 false (S)-3-Hydroxydodecanoyl-CoA + NAD → 3-Oxododecanoyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT 3-ketoacyl-CoA thiolase Reaction3783 false (2E)-Dodecenoyl-CoA → (S)-3-Hydroxydodecanoyl-CoA + Water LEFT_TO_RIGHT ReactionCatalysis3757 ACTIVATION 1.0 Reaction3782 false 3Z-dodecenoyl-CoA → (2E)-Dodecenoyl-CoA LEFT_TO_RIGHT Short-chain-fatty-acid--CoA ligase Reaction3781 true Hydrogen Ion + Lauroyl-CoA + an oxidized electron-transfer flavoprotein  → (2E)-Dodecenoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT ReactionCatalysis3755 ACTIVATION 6816 PubChem-compound ReactionCatalysis3758 ACTIVATION ReactionCatalysis3759 ACTIVATION CHEBI:15846 ChEBI Reaction3785 false 3-Oxododecanoyl-CoA + Coenzyme A → Acetyl-CoA + Tetradecanoyl-CoA LEFT_TO_RIGHT Lauroyl-CoA HMDB01206 HMDB 1.0 5742 ChemSpider 440604 PubChem-compound 1038 PubChem-compound 440603 PubChem-compound HMDB59597 HMDB Adenosine monophosphate C12H24O2 Dodecanoic acid 200.17763 HMDB00902 HMDB CHEBI:16908 ChEBI 5858 ChemSpider fatty acid oxidation (laurate) Acetyl-CoA 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS 45266564 PubChem-compound 1.0 C33H52N7O17P3S (2E)-Dodecenoyl-CoA 943.23535 1.0 HMDB01423 HMDB CHEBI:15521 ChEBI Hydrogen Ion P76082 UniProt CHEBI:5086 ChEBI HMDB04257 HMDB Adenosine triphosphate LAUROYLCOA-CPD BioCyc 58-68-4 CAS SMILES CCCCCCCCCCCC(O)=O Reduced electron-transfer flavoprotein CHEBI:15532 ChEBI 1.0 C00001 KEGG Compound CHEBI:57330 ChEBI C00004 KEGG Compound TETRADECANOYL-COA BioCyc C00003 KEGG Compound C00002 KEGG Compound C05263 KEGG Compound Fatty acid oxidation complex subunit alpha C05262 KEGG Compound CHEBI:27868 ChEBI Tetradecanoyl-CoA an oxidized electron-transfer flavoprotein  C35H62N7O17P3S Tetradecanoyl-CoA 977.3136 3130-72-1 CAS 389502 ChemSpider 389501 ChemSpider HMDB01521 HMDB C02679 KEGG Compound C21H28N7O14P2 NAD 664.11694 P21151 UniProt C00010 KEGG Compound 3-ketoacyl-CoA thiolase_ 1.0 3-ketoacyl-CoA thiolase Short-chain-fatty-acid--CoA ligase 3893 PubChem-compound C33H56N7O17P3S 3Z-dodecenoyl-CoA 947.2666 C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound 2,3-dehydroadipyl-CoA hydratase P76503 UniProt HMDB03936 HMDB HMDB03937 HMDB fatty acid oxidation (myristate) SubPathway P77399 UniProt H Hydrogen Ion 1.007825 (2E)-Dodecenoyl-CoA HMDB03712 HMDB 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS C00024 KEGG Compound 3-Oxododecanoyl-CoA ReactionCatalysis3735 ACTIVATION C33H58N7O18P3S (S)-3-Hydroxydodecanoyl-CoA 965.27716 C33H56N7O18P3S 3-Oxododecanoyl-CoA 963.26154 1.0 (S)-3-Hydroxydodecanoyl-CoA SubPathwayInteraction2090 SubPathwayReaction SubPathway2090Reaction P38135 UniProt 72059-49-5 CAS 58623 ChemSpider 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 1.0 5682 ChemSpider Reduced electron-transfer flavoprotein SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Fatty acid oxidation complex subunit alpha_ AMP BioCyc Water SMILES CCCCCCCC\C=C/CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H](C(O)[C@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 FadJ component of anaerobic fatty acid oxidation complex CO-A BioCyc 16061154 PubChem-compound 72-89-9 CAS Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 C02593 KEGG Compound CHEBI:27668 ChEBI SMILES CCCCCCCCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 SMILES CCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 HMDB00538 HMDB CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Fatty acid oxidation complex subunit alpha 7732-18-5 CAS 388299 ChemSpider 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 1.0 26330706 ChemSpider SMILES CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 C01832 KEGG Compound C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 3-ketoacyl-CoA thiolase_ 2,3-dehydroadipyl-CoA hydratase 1.0 165436 PubChem-compound CHEBI:30805 ChEBI HMDB00638 HMDB 962 PubChem-compound 143-07-7 CAS 392413 ChemSpider 2.0 2152-91-2 CAS 145018 ChemSpider C03221 KEGG Compound 5893 PubChem-compound 1.0 HMDB02111 HMDB C00080 KEGG Compound Dodecanoic acid SMP01036 SMPDB SMP01037 SMPDB CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] 1.0 C02944 KEGG Compound CPD-7221 BioCyc SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB03571 HMDB CPD-7222 BioCyc Fatty acid oxidation complex subunit alpha_ 1.0 HMDB01487 HMDB 444493 PubChem-compound 6083 PubChem-compound acetyl-CoA C-acyltransferase 6244-92-4 CAS SMILES CCCCCCCCC\C=C\C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(=O)([O-])[O-])N1C=NC2=C1N=CN=C2N B7L9A7 UniProt an oxidized electron-transfer flavoprotein  ACETYL-COA BioCyc H2O Water 18.010565 NADH BioCyc NAD BioCyc 3756 ChemSpider HMDB00045 HMDB 1066-12-2 CAS CHEBI:15351 ChEBI 6.2.1.- false 6.2.1.- Adenosine triphosphate + Coenzyme A + Dodecanoic acid → Adenosine monophosphate + Lauroyl-CoA LEFT_TO_RIGHT 85-61-0 CAS SMILES CCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Short-chain- fatty-acid-- CoA ligase Fatty acid oxidation complex subunit alpha_ Fatty acid oxidation complex subunit alpha 2,3- dehydroadipyl- CoA hydratase 2,3- dehydroadipyl- CoA hydratase 3-ketoacyl-CoA thiolase_ 3-ketoacyl-CoA thiolase Dodecanoic acid CoA ATP AMP Lauroyl-CoA H + (2E)- Dodecenoyl- CoA 3Z- dodecenoyl- CoA H 2 O (S)-3- Hydroxydodecanoyl- CoA NAD NADH H + 3- Oxododecanoyl- CoA CoA Acetyl-CoA Tetradecanoyl- CoA an oxidized electron- transfer flavoprotein Reduced electron- transfer flavoprotein fatty acid oxidation (myristate)
1.0 C23H38N7O17P3S Acetyl-CoA 809.1258 65113 PubChem-compound 78303-19-2 CAS 17220833 ChemSpider 937 ChemSpider NADH 439153 PubChem-compound 3Z-dodecenoyl-CoA SMILES O C10H14N5O7P Adenosine monophosphate 347.06308 1.0 C33H58N7O17P3S Lauroyl-CoA 949.2823 CHEBI:16027 ChEBI NAD PW001020 PathWhiz ATP BioCyc PW001021 PathWhiz ReactionCatalysis3756 ACTIVATION Reaction3784 false (S)-3-Hydroxydodecanoyl-CoA + NAD → 3-Oxododecanoyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT 3-ketoacyl-CoA thiolase Reaction3783 false (2E)-Dodecenoyl-CoA → (S)-3-Hydroxydodecanoyl-CoA + Water LEFT_TO_RIGHT ReactionCatalysis3757 ACTIVATION 1.0 Reaction3782 false 3Z-dodecenoyl-CoA → (2E)-Dodecenoyl-CoA LEFT_TO_RIGHT Short-chain-fatty-acid--CoA ligase Reaction3781 true Hydrogen Ion + Lauroyl-CoA + an oxidized electron-transfer flavoprotein  → (2E)-Dodecenoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT ReactionCatalysis3755 ACTIVATION 6816 PubChem-compound ReactionCatalysis3758 ACTIVATION ReactionCatalysis3759 ACTIVATION CHEBI:15846 ChEBI Reaction3785 false 3-Oxododecanoyl-CoA + Coenzyme A → Acetyl-CoA + Tetradecanoyl-CoA LEFT_TO_RIGHT Lauroyl-CoA HMDB01206 HMDB 1.0 5742 ChemSpider 440604 PubChem-compound 1038 PubChem-compound 440603 PubChem-compound HMDB59597 HMDB Adenosine monophosphate C12H24O2 Dodecanoic acid 200.17763 HMDB00902 HMDB CHEBI:16908 ChEBI 5858 ChemSpider fatty acid oxidation (laurate) Acetyl-CoA 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS 45266564 PubChem-compound 1.0 C33H52N7O17P3S (2E)-Dodecenoyl-CoA 943.23535 1.0 HMDB01423 HMDB CHEBI:15521 ChEBI Hydrogen Ion P76082 UniProt CHEBI:5086 ChEBI HMDB04257 HMDB Adenosine triphosphate LAUROYLCOA-CPD BioCyc 58-68-4 CAS SMILES CCCCCCCCCCCC(O)=O Reduced electron-transfer flavoprotein CHEBI:15532 ChEBI 1.0 C00001 KEGG Compound CHEBI:57330 ChEBI C00004 KEGG Compound TETRADECANOYL-COA BioCyc C00003 KEGG Compound C00002 KEGG Compound C05263 KEGG Compound Fatty acid oxidation complex subunit alpha C05262 KEGG Compound CHEBI:27868 ChEBI Tetradecanoyl-CoA an oxidized electron-transfer flavoprotein  C35H62N7O17P3S Tetradecanoyl-CoA 977.3136 3130-72-1 CAS 389502 ChemSpider 389501 ChemSpider HMDB01521 HMDB C02679 KEGG Compound C21H28N7O14P2 NAD 664.11694 P21151 UniProt C00010 KEGG Compound 3-ketoacyl-CoA thiolase_ 1.0 3-ketoacyl-CoA thiolase Short-chain-fatty-acid--CoA ligase 3893 PubChem-compound C33H56N7O17P3S 3Z-dodecenoyl-CoA 947.2666 C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound 2,3-dehydroadipyl-CoA hydratase P76503 UniProt HMDB03936 HMDB HMDB03937 HMDB P77399 UniProt H Hydrogen Ion 1.007825 (2E)-Dodecenoyl-CoA HMDB03712 HMDB 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS C00024 KEGG Compound 3-Oxododecanoyl-CoA ReactionCatalysis3735 ACTIVATION C33H58N7O18P3S (S)-3-Hydroxydodecanoyl-CoA 965.27716 C33H56N7O18P3S 3-Oxododecanoyl-CoA 963.26154 1.0 (S)-3-Hydroxydodecanoyl-CoA SubPathwayInteraction2090 SubPathwayReaction SubPathway2090Reaction P38135 UniProt 72059-49-5 CAS 58623 ChemSpider 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 1.0 5682 ChemSpider Reduced electron-transfer flavoprotein SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Fatty acid oxidation complex subunit alpha_ AMP BioCyc Water SMILES CCCCCCCC\C=C/CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H](C(O)[C@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 FadJ component of anaerobic fatty acid oxidation complex CO-A BioCyc 16061154 PubChem-compound 72-89-9 CAS Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 C02593 KEGG Compound CHEBI:27668 ChEBI SMILES CCCCCCCCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 SMILES CCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 HMDB00538 HMDB CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Fatty acid oxidation complex subunit alpha 7732-18-5 CAS 388299 ChemSpider 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 1.0 26330706 ChemSpider SMILES CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 C01832 KEGG Compound C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 3-ketoacyl-CoA thiolase_ 2,3-dehydroadipyl-CoA hydratase 1.0 165436 PubChem-compound CHEBI:30805 ChEBI HMDB00638 HMDB 962 PubChem-compound 143-07-7 CAS 392413 ChemSpider 2.0 2152-91-2 CAS 145018 ChemSpider C03221 KEGG Compound 5893 PubChem-compound 1.0 HMDB02111 HMDB C00080 KEGG Compound Dodecanoic acid http://identifiers.org/smpdb/SMP01036 SMPDB http://identifiers.org/smpdb/SMP01037 SMPDB CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] fatty acid oxidation (myristate) SubPathway 1.0 C02944 KEGG Compound CPD-7221 BioCyc SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB03571 HMDB CPD-7222 BioCyc Fatty acid oxidation complex subunit alpha_ 1.0 HMDB01487 HMDB 444493 PubChem-compound 6083 PubChem-compound acetyl-CoA C-acyltransferase 6244-92-4 CAS SMILES CCCCCCCCC\C=C\C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(=O)([O-])[O-])N1C=NC2=C1N=CN=C2N B7L9A7 UniProt an oxidized electron-transfer flavoprotein  ACETYL-COA BioCyc H2O Water 18.010565 NADH BioCyc NAD BioCyc 3756 ChemSpider HMDB00045 HMDB 1066-12-2 CAS CHEBI:15351 ChEBI 6.2.1.- false 6.2.1.- Adenosine triphosphate + Coenzyme A + Dodecanoic acid → Adenosine monophosphate + Lauroyl-CoA LEFT_TO_RIGHT 85-61-0 CAS SMILES CCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N fadK fadJ fadB paaF paaF fadI fadA Dodecanoic acid Coenzyme A Adenosine triphosphate Adenosine monophosphate Lauroyl-CoA Hydrogen Ion (2E)- Dodecenoyl- CoA 3Z- dodecenoyl- CoA Water (S)-3- Hydroxydodecanoyl- CoA NAD NADH Hydrogen Ion 3- Oxododecanoyl- CoA Coenzyme A Acetyl-CoA Tetradecanoyl- CoA an oxidized electron- transfer flavoprotein Reduced electron- transfer flavoprotein fatty acid oxidation (myristate)