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Vitamin B12 transporter BtuB Protein tonB Biopolymer transport protein exbB Biopolymer transport protein exbD Vitamin B12 transporter BtuB Protein tonB Biopolymer transport protein exbB Biopolymer transport protein exbD Cob(I)yrinic acid a,c-diamide adenosyltransferase Bifunctional adenosylcobalamin biosynthesis protein cobU Bifunctional adenosylcobalamin biosynthesis protein cobU Nicotinate- nucleotide-- dimethylbenzimidazole phosphoribosyltransferase Cobalamin synthase Alpha-ribazole phosphatase Cob(I)yrinic acid a,c-diamide adenosyltransferase Vitamin B12-binding protein Vitamin B12 import system permease protein BtuC Vitamin B12-binding protein Cobinamide Cobinamide Cyanocobalamin Cyanocobalamin Cobinamide ATP Adenosyl cobinamide Triphosphate ATP ADP H + adenosylcobinamide phosphate GTP H + PP i Adenosylcobinamide- GDP Dimethylbenzimidazole nicotinate β-D- ribonucleotide H + Nicotinic acid N1-(5- Phospho-a-D- ribosyl)-5,6- dimethylbenzimidazole Adenosylcobinamide- GDP H + GMP adenosylcobalamin 5'-phosphate H 2 O P i coenzyme B12 Cobalamin ATP PPPi ATP H 2 O ADP P i H + Cobinamide ATP H 2 O ADP P i H + Cyanocobalamin Vitamin B12 import ATP-binding protein BtuD Vitamin B12 import system permease protein BtuC Vitamin B12 import ATP-binding protein BtuD
btuB tonB exbB exbD btuB tonB exbB exbD btuR cobU cobU cobT cobS cobC btuR btuF btuC btuF Cobinamide Cobinamide Cyanocobalamin Cyanocobalamin Cobinamide Adenosine triphosphate Adenosyl cobinamide Triphosphate Adenosine triphosphate Adenosine diphosphate Hydrogen Ion adenosylcobinamide phosphate Guanosine triphosphate Hydrogen Ion Pyrophosphate Adenosylcobinamide- GDP Dimethylbenzimidazole nicotinate β-D- ribonucleotide Hydrogen Ion Nicotinic acid N1-(5- Phospho-a-D- ribosyl)-5,6- dimethylbenzimidazole Adenosylcobinamide- GDP Hydrogen Ion GMP adenosylcobalamin 5'-phosphate Water Phosphate coenzyme B12 Cobalamin Adenosine triphosphate PPPi Adenosine triphosphate Water Adenosine diphosphate Phosphate Hydrogen Ion Cobinamide Adenosine triphosphate Water Adenosine diphosphate Phosphate Hydrogen Ion Cyanocobalamin btuD btuC btuD